Biomimetic total synthesis of gambogin and rate acceleration of pericyclic reactions in aqueous media

Angewandte Chemie - International Edition

Volumn 44, Issue 5, 2005, Pages 756-761

  Nicolaou, K C ^a,b   Xu, Hao ^a   Wartmann, Markus ^c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Claisen rearrangement; Diels Alder reaction; Natural products; Rate acceleration; Total synthesis

Indexed keywords

ACCELERATION; CASCADES (FLUID MECHANICS); REACTION KINETICS; SYNTHESIS (CHEMICAL); WATER;

CLAISEN/DIELS-ALDER REACTIONS; GAMBOGIN; PERICYCLIC REACTIONS; RATE ACCELERATION;

BIOMIMETIC MATERIALS;

CYTOTOXIC AGENT; GAMBOGIN; GARCINA HAMBURYI EXTRACT; PHLOROGLUCINOL; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; DESILYLATION; DIELS ALDER REACTION; DRUG SYNTHESIS; GARCINA HAMBURYI; HUMAN; HUMAN CELL; LITHIATION; MEDICINAL PLANT; OXIDATION; REACTION ANALYSIS;

ALKENES; BRIDGED COMPOUNDS; CELL LINE, TUMOR; HUMANS; KINETICS; MOLECULAR MIMICRY; WATER;

EID: 13444263819     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200462211     Document Type: Article

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