A new γ-interferon-inducible promoter and splice variants of an anti-angiogenic human tRNA synthetase

Nucleic Acids Research

Volumn 32, Issue 2, 2004, Pages 719-727

  Liu, Jianming ^a   Shue, Eveline ^a   Ewalt, Karla L ^a   Schimmel, Paul ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; ERYTHROPOIETIN; GAMMA INTERFERON; INTERLEUKIN 4; LYMPHOTOXIN;

5' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME MECHANISM; EXPRESSED SEQUENCE TAG; GENE EXPRESSION; GENETIC TRANSFECTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MOLECULAR CLONING; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

5' UNTRANSLATED REGIONS; ALTERNATIVE SPLICING; ANGIOGENESIS INHIBITORS; BASE SEQUENCE; CELLS, CULTURED; DNA-BINDING PROTEINS; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HELA CELLS; HUMANS; INTERFERON REGULATORY FACTOR-1; INTERFERON TYPE II; ISOENZYMES; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; TRYPTOPHAN-TRNA LIGASE;

EID: 1342327657     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh240     Document Type: Article

References (48)

1. Schimmel,P. (1987) Aminoacyl tRNA synthetases: general scheme of structure-function relationships in the polypeptides and recognition of transfer RNAs. Annu. Rev. Biochem., 56, 125-158.
2. Moras,D. (1992) Structural and functional relationships between aminoacyl-tRNA synthetases. Trends Biochem. Sci., 17, 159-164.
3. Webster,T., Tsai,H., Kula,M., Mackie,G.A. and Schimmel,P. (1984) Specific sequence homology and three-dimensional structure of an aminoacyl transfer RNA synthetase. Science, 226, 1315-1317.
4. Ludmerer,S.W. and Schimmel,P. (1987) Gene for yeast glutamine tRNA synthetase encodes a large amino-terminal extension and provides a strong confirmation of the signature sequence for a group of the aminoacyl-tRNA synthetases. J. Biol. Chem., 262, 10801-10806.
5. Eriani,G., Delarue,M., Poch,O., Gangloff,J. and Moras,D. (1990) Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs. Nature, 347, 203-206.
6. Cusack,S., Berthet-Colominas,C., Härtlein,M., Nassar,N. and Leberman,R. (1990) A second class of synthetase structure revealed by X-ray analysis of Escherichia coli seryl-tRNA synthetase at 2.5 Å. Nature, 347, 249-255.
7. Rao,S.T. and Rossmann,M.G. (1973) Comparison of super-secondary structures in proteins. J. Mol. Biol., 76, 241-256.
8. Ruff,M., Krishnaswamy,S., Boeglin,M., Poterszman,A., Mitschler,A., Podjarny,A., Rees,B., Thierry,J.C. and Moras,D. (1991) Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp). Science, 252, 1682-1689.
9. Martinis,S.A., Plateau,P., Cavarelli,J. and Florentz,C. (1999) Aminoacyl-tRNA synthetases: a family of expanding functions. EMBO J., 18, 4591-4596.
10. Francklyn,C., Perona,J.J., Puetz,J. and Hou,Y.M. (2002) Aminoacyl-tRNA synthetases: versatile players in the changing theater of translation. RNA, 8, 1363-1372.
11. Wakasugi,K. and Schimmel,P. (1999) Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Science, 284, 147-151.
12. Wakasugi,K., Slike,B.M., Hood,J., Ewalt,K.L., Cheresh,D.A. and Schimmel,P. (2002) Induction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase. J. Biol. Chem., 277, 20124-20126.
13. Wakasugi,K., Slike,B.M., Hood,J., Otani,A., Ewalt,K.L., Friedlander,M., Cheresh,D.A. and Schimmel,P. (2002) A human aminoacyl-tRNA synthetase as a regulator of angiogenesis. Proc. Natl Acad. Sci. USA, 99, 173-177.
14. Otani,A., Slike,B.M., Dorrell,M.I., Hood,J., Kinder,K., Ewalt,K.L., Cheresh,D., Schimmel,P. and Friedlander,M. (2002) A fragment of human TrpRS as a potent antagonist of ocular angiogenesis. Proc. Natl Acad. Sci. USA, 99, 178-183.
15. Ko,Y.G., Kim,E.Y., Kim,T., Park,H., Park,H.S., Choi,E.J. and Kim,S. (2001) Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1. J. Biol. Chem., 276, 6030-6036.
16. Howard,O.M., Dong,H.F., Yang,D., Raben,N., Nagaraju,K., Rosen,A., Casciola-Rosen,L., Härtlein,M., Kron,M., Yiadom,K. et al. (2002) Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells. J. Exp. Med., 196, 781-791.
17. Ko,Y.G., Kang,Y.S., Kim,E.K., Park,S.G. and Kim,S. (2000) Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis. J. Cell Biol., 149, 567-574.
18. Akins,R.A. and Lambowitz,A.M. (1987) A protein required for splicing group 1 introns in Neurospora mitochondria is mitochondrial tyrosyl-tRNA synthetase or a derivative thereof. Cell, 50, 331-345.
19. Kämper,U., Kuck,U., Cherniack,A.D. and Lambowitz,A.M. (1992) The mitochondrial tyrosyl-tRNA synthetase of Podospora anserina is a bifunctional enzyme active in protein synthesis and RNA splicing. Mol. Cell. Biol., 12, 499-511.
20. Rho,S.B. and Martinis,S.A. (2000) The bl4 group I intron binds directly to both its protein splicing partners, a tRNA synthetase and maturase, to facilitate RNA splicing activity. RNA, 6, 1882-1894.
21. Scheinker,V.S., Beresten,S.F., Degtyarev,S.K. and Kisselev,L.L. (1979) The effect of tRNA and tryptophanyl adenylate on limited proteolysis of beef pancreas tryptophanyl-tRNA synthetase. Nucleic Acids Res., 7, 625-637.
22. Favorova,O.O., Zargarova,T.A., Rukosuyev,V.S., Beresten,S.F. and Kisselev,L.L. (1989) Molecular and cellular studies of tryptophanyl-tRNA synthetases using monoclonal antibodies. Remarkable variations in the content of tryptophanyl-tRNA synthetase in the pancreas of different mammals. Eur. J. Biochem., 184, 583-588.
23. Tolstrup,A.B., Bejder,A., Fleckner,J. and Justesen,J. (1995) Transcriptional regulation of the interferon-gamma-inducible tryptophanyl-tRNA synthetase includes alternative splicing. J. Biol. Chem., 270, 397-403.
24. Shaw,A.C., Røssel Larsen,M., Roepstorff,P., Justesen,J., Christiansen,G. and Birkelund,S. (1999) Mapping and identification of interferon gamma-regulated HeLa cell proteins separated by immobilized pH gradient two-dimensional gel electrophoresis. Electrophoresis, 20, 984-993.
25. Turpaev,K.T., Zakhariev,V.M., Sokolova,I.V., Narovlyansky,A.N., Amchenkova,A.M., Justesen,J. and Frolova,L.Y. (1996) Alternative processing of the tryptophanyl-tRNA synthetase mRNA from interferon-treated human cells. Eur. J. Biochem., 240, 732-737.
26. Aiello,L.P., Pierce,E.A., Foley,E.D., Takagi,H., Chen,H., Riddle,L., Ferrara,N., King,G.L. and Smith,L.E. (1995) Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc. Natl Acad. Sci. USA, 92, 10457-10461.
27. Shih,S.C., Robinson,G.S., Perruzzi,C.A., Calvo,A., Desai,K., Green,J.E., Ali,I.U., Smith,L.E. and Senger,D.R. (2002) Molecular profiling of angiogenesis markers. Am. J. Pathol., 161, 35-41.
28. Stark,G.R., Kerr,I.M., Williams,B.R., Silverman,R.H. and Schreiber,R.D. (1998) How cells respond to interferons. Annu. Rev. Biochem., 67, 227-264.
29. Farber,J.M. (1993) HuMig: a new human member of the chemokine family of cytokines. Biochem. Biophys. Res. Commun., 192, 223-230.
30. Strieter,R.M., Kunkel,S.L., Arenberg,D.A., Burdick,M.D. and Polverini,P.J. (1995) Interferon gamma-inducible protein 10 (IP-10), a member of the C-X-C chemokine family, is an inhibitor of angiogenesis. Biochem. Biophys. Res. Commun., 210, 51-57.
31. Bange,F.C., Flohr,T., Buwitt,U. and Böttger,E.C. (1992) An interferon-induced protein with release factor activity is a tryptophanyl-tRNA synthetase. FEBS Lett., 300, 162-166.
32. Fleckner,J., Martensen,P.M., Tolstrup,A.B., Kjeldgaard,N.O. and Justesen,J. (1995) Differential regulation of the human, interferon inducible tryptophanyl-tRNA synthetase by various cytokines in cell lines. Cytokine, 7, 70-77.
33. Barceló-Batllori,S., André,M., Servis,C., Lévy,N., Takikawa,O., Michetti,P., Reymond,M. and Felley-Bosco,E. (2002) Proteomic analysis of cytokine induced proteins in human intestinal epithelial cells: implications for inflammatory bowel diseases. Proteomics, 2, 551-560.
34. Sambrook,J., Fritsch,E.F. and Maniatis,T. (2000) Molecular Cloning: A Laboratory Manual, 3rd Edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
35. Quandt,K., Frech,K., Karas,H., Wingender,E. and Werner,T. (1995) MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res., 23, 4878-4884.
36. Frolova,L.Y., Grigorieva,A.Y., Sudomoina,M.A. and Kisselev,L.L. (1993) The human gene encoding tryptophanyl-tRNA synthetase: interferon-response elements and exon-intron organization. Gene, 128, 237-245.
37. Yuan,W., Collado-Hidalgo,A., Yufit,T., Taylor,M. and Varga,J. (1998) Modulation of cellular tryptophan metabolism in human fibroblasts by transforming growth factor-beta: selective inhibition of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA synthetase gene expression. J. Cell. Physiol., 177, 174-186.
38. Födinger,M., Fritsche-Polanz,R., Buchmayer,H., Skoupy,S., Sengoelge,G., Hörl,W.H. and Sunder-Plassmann,G. (2000) Erythropoietin-inducible immediate-early genes in human vascular endothelial cells. J. Invest. Med., 48, 137-149.
39. Matsunaga,T., Ishida,T., Takekawa,M., Nishimura,S., Adachi,M. and Imai,K. (2002) Analysis of gene expression during maturation of immature dendritic cells derived from peripheral blood monocytes. Scand. J. Immunol., 56, 593-601.
40. Ewalt,K.L. and Schimmel,P. (2002) Activation of angiogenic signaling pathways by two human tRNA synthetases. Biochemistry, 41, 13344-13349.
41. Blanco,J.C., Contursi,C., Salkowski,C.A., DeWitt,D.L., Ozato,K. and Vogel,S.N. (2000) Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon gamma-dependent cyclooxygenase 2 expression. J. Exp. Med., 191, 2131-2144.
42. Storm van's Gravesande,K., Layne,M.D., Ye,Q., Le,L., Baron,R.M., Perrella,M.A., Santambrogio,L., Silverman,E.S. and Riese,R.J. (2002) IFN regulatory factor-1 regulates IFN-gamma-dependent cathepsin S expression. J. Immunol., 168, 4488-4494.
43. Yamamoto,H., Lamphier,M.S., Fujita,T., Taniguchi,T. and Harada,H. (1994) The oncogenic transcription factor IRF-2 possesses a transcriptional repression and a latent activation domain. Oncogene, 9, 1423-1428.
44. Yang,D., Nakada-Tsukui,K., Ohtani,M., Goto,R., Yoshimura,T., Kobayashi,Y. and Watanabe,N. (2001) Identification and cloning of genes associated with the guinea pig skin delayed-type hypersensitivity reaction. J. Biochem. (Tokyo), 129, 561-568.
45. Seshaiah,P. and Andrew,D.J. (1999) WRS-85D: a tryptophanyl-tRNA synthetase expressed to high levels in the developing Drosophila salivary gland. Mol. Biol. Cell, 10, 1595-1608.
46. Gromov,P., Skovgaard,G.L., Palsdottir,H., Gromova,I., Østergaard,M. and Celis,J.E. (2003) Protein profiling of the human epidermis from the elderly reveals up-regulation of a signature of interferon-gamma-induced polypeptides that includes manganese-superoxide dismutase and the p85-beta subunit of phosphatidylinositol 3-kinase. Mol. Cell. Proteomics, 2, 70-84.
47. Aboagye-Mathiesen,G., Ebbesen,P., von der Maase,H. and Celis,J.E. (1999) Interferon gamma regulates a unique set of proteins in fresh human bladder transitional cell carcinomas. Electrophoresis, 20, 344-348.
48. Kumatori,A., Yang,D., Suzuki,S. and Nakamura,M. (2002) Cooperation of STAT-1 and IRF-1 in interferon-gamma-induced transcription of the gp91(phox) gene. J. Biol. Chem., 277, 9103-9111.