Anti-inflammatory effect of erythromycin on histamine-induced otitis media with effusion in guinea pigs

Journal of Laryngology and Otology

Volumn 118, Issue 2, 2004, Pages 97-101

  Aktan, Bülent ^a,b   Gundogdu, Cemal ^a   Ucuncu, Harun ^a   Unal, Bunyami ^a   Sütbeyaz, Yavuz ^a   Altas, Sare ^a  

^a ATATURK UNIVERSITY   (Turkey)

^b ATATÜRK UNIVERSITY   (Turkey)

Author keywords

Erythromycin; Guinea Pigs; Otitis Media with Effusion

Indexed keywords

ERYTHROMYCIN; HISTAMINE; METHYLPREDNISOLONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL ANIMAL; EXPERIMENTAL MODEL; GUINEA PIG; MIDDLE EAR; NEUTROPHIL CHEMOTAXIS; NONHUMAN; SAMPLE; SECRETORY OTITIS MEDIA; STATISTICAL SIGNIFICANCE; TEMPORAL BONE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ERYTHROMYCIN; GLUCOCORTICOIDS; GUINEA PIGS; HISTAMINE; METHYLPREDNISOLONE; NEUTROPHIL INFILTRATION; OTITIS MEDIA WITH EFFUSION; RANDOM ALLOCATION; TEMPORAL BONE; VASODILATION;

EID: 1342322708     PISSN: 00222151     EISSN: None     Source Type: Journal    
DOI: 10.1258/002221504772784522     Document Type: Article

References (29)

1. Boisvert P, Wasserman SI, Schiff M, Ryan AF. Histamine-induced middle ear effusion and mucosal histopathology in the guinea pig. Ann Otol Rhinol Laryngol 1985;94:212-6
2. Skoner DP, Stillwagon PK, Casselbrandt ML, Tanner EP, Doyle WJ, Fireman P. Inflammatory mediators in chronic otitis media with effusion. Arch Otolaryngol Head Neck Surg 1988;114:1131-3
3. Goldie P, Hellstrom S, Idahl LA. Middle ear effusion induced by various inflammatory mediators and neuropeptides. An experimental study in the rat. Acta Otolaryngol 1989;108:246-52
4. Rhee CK, Jung TT, Miller S, Weeks D. Experimental otitis media with effusion induced by platelet activating factor. Ann Otol Rhinol Laryngol 1993;102:600-5
5. Chambers HF. Protein synthesis inhibitors and miscellaneous antibacterial agents. In: Hardman JG, Limbird LE, eds. The Pharmacological Basis of Therapeutics. 10 edn. New York: McGraw-Hill, 2001:1239-71
6. Takahashi Y, Shimizu T, Sakakura Y. Effects of indomethacin, dexamethasone and erythromycin on endotoxin-induced intraepithelial mucus production of rat nasal epithelium. Ann Otol Rhinol Laryngol 1997;106:683-7
7. Sugiura Y, Ohashi Y, Nakai Y. Roxythromycin stimulates the mucociliary activity of the Eustachian tube and modulates neutrophil activity in the healthy guinea pig. Acta Otolaryngol (Suppl) 1997;531:34-8
8. Enomoto F, Ichikawa G, Nagaoka I, Yamashita T. Effect of erythromycin on otitis media with effusion in experimental rat model. Acta Oto-Laryngol Suppl 1998;539:57-60
9. Ianaro A, Ialenti A, Maffia P, Sautebin L, Rombola L, Carnuccio R, et al. Anti-inflammatory activity of macrolide antibiotics. J Pharmacol Exp Ther 2000;292:156-63
10. Iino Y, Sugita K, Toriyama M, Kudo K. Erythromycin therapy for otitis media with effusion in sinobronchial syndrome. Arch Otolaryngol Head Neck Surg 1993;119:648-51
11. Fujii T, Kadota J, Kawakami K, Iida K, Shirai R, Kaseda M, et al. Long term effect of erythromycin therapy in patients with chronic pseudomonas aeruginosa infection. Thorax 1995;50:1246-52
12. Ernstson S, Sundberg L. Erythromycin in the treatment of otitis media with effusion. J Laryngol Otol 1984;98:767-9
13. Sterio DC. The unbiased estimation of number and sizes of arbitrary particles using the dissector. J Microsc 1984;134:127-36
14. Unal B, Bradley PM, Sahin B, Canan S, Aslan H, Kaplan S. Estimation of numerical density and mean synaptic height in chick hippocampus 24 and 48 hours after passive avoidance training. Brain Res Dev Brain Res 2002;136:135-44
15. Cruz-Orive LM, Weibel ER. Recent stereological methods for cell biology: a brief survey. Am J Physiol 1990;258:L148-56
16. Gundersen HJ. Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. J Microsc 1986;143:3-45
17. Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Moller A, Nielsen K, et al. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 1988;96:379-94
18. Gundersen HJG, Jensen EB. The efficiency of systematic sampling in stereology and its prediction. J Microsc 1987;147:229-63
19. Norlander T, Forsgren K, Kumlien J, Stierna P, Carlsoo B. Cellular regeneration and recovery of the maxillary sinus mucosa. An experimental study in rabbits. Acta OtoLaryngol Suppl 1992;492:33-7
20. Polosukhin VV. Ultrastructure of the blood and lymphatic capillaries of the respiratory tissue during inflammation and endobronchial laser therapy. Ultrastruct Pathol 2000;24:183-9
21. Knipping S, Holzhausen HJ, Mir Salim PA, Berghaus A. Chronic rhinosinusitis in hypogammaglobulinemia. A morphological study. HNO 2002;50:644-8
22. Engelke W, Schwarzwaller W, Behnsen A, Jacobs HG. Subantroscopic laterobasal sinus floor augmentation (SALSA): an up-to-5-year clinical study. Int J Oral Maxillofac Implants 2003;18:135-43
23. Fagerland JA, Hagemoser WA, Ireland WP. Ultrastructure and stereology of leukocytes and platelets of normal foxes and a fox with a Chediak-Higashi-like syndrome. Vet Pathol 1987;24:164-9
24. Norlander T, Westrin KM, Stierna P. The inflammatory response of the sinus and nasal mucosa during sinusitis: implications for research and therapy. Acta Otolaryngol Suppl 1994;515:38-44
25. Suzuki H, Takahashi Y, Wataya H, Ikeda K, Nakabayashi S, Shimomura A, et al. Mechanism of neutrophil recruitment induced by IL-8 in chronic sinusitis. J Allergy Clin Immunol 1996;98:659-70
26. Lundberg C, Engquist S. Localization of bacteria and the cause of tissue destruction in maxillary sinusitis. Acta OtoLaryngol Suppl 1984;407:30-2
27. Suzuki H, Asada Y, Ikeda K, Oshima T, Takasaka T. Inhibitory effect of erythromycin on interleukin-8 secretion from exudative cells in the nasal discharge of patients with chronic sinusitis. Laryngoscope 1999;109:407-10
28. Kadota J, Sakito O, Kohno S, Sawa H, Mukae H, Oda H, et al. A mechanism of erythromycin treatment in patients with diffuse panbronchiolitis. Am Rev Respir Dis 1993;147:153-9
29. Tamaoki J, Chiyotani A, Sasaki N, Takeyama K, Takizawa K. Effect of erythromycin on ciliary motility in rabbit airway epithelium in vitro. J Antimicrobial Chemother 1992;29:173-8