Anandamide content and interaction of endocannabinoid/GABA modulatory effects in the NTS on baroreflex-evoked sympathoinhibition

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 286, Issue 3 55-3, 2004, Pages

  Seagard, Jeanne L ^a,b   Dean, Caron ^a   Patel, Sachin ^a   Rademacher, David J ^a   Hopp, Francis A ^a   Schmeling, William T ^a   Hillard, Cecilia J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Arachidonylethanolamide; Baroreceptor; CB1 receptor; SR 141716; Sympathetic activity

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ANANDAMIDE; BICUCULLINE; CANNABINOID 1 RECEPTOR; CANNABINOID DERIVATIVE; ENDOCANNABINOID; PHENYLEPHRINE; RIMONABANT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERTENSION; MALE; MECHANORECEPTOR; MICROINJECTION; MODULATION; NERVE CONDUCTION; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRESSORECEPTOR REFLEX; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; RAT; SOLITARY TRACT NUCLEUS; SYMPATHETIC NERVE;

EID: 1342304201     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00870.2003     Document Type: Article

References (54)

1. Andresen MC and Kunze DL. Nucleus tractus solitarius-gateway to neural circulatory control. Annu Rev Physiol 56: 93-116, 1994.
2. Andresen MC and Yang M. Excitatory amino acid receptors and afferent synaptic transmission in the nucleus tractus solitarius. In: Nucleus of the Solitary Tract, edited by Barraco IRA. Boca Raton, FL: CRC, 1993, p. 187-192.
3. Bisogno T, Berrendero F, Ambrosino G, Cebeira M, Ramos JA, Fernandez-Ruiz JJ, and Di Marzo V. Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function. Biochem Biophys Res Commun 256: 377-380, 1999.
4. Bonham AC and Chen CY. Glutamatergic neural transmission in the nucleus tractus solitarius: N-methyl-D-aspartate receptors. Clin Exp Pharmacol Physiol 29: 497-502, 2002.
5. Bousquet P, Feldman J, Bloch R, and Schwartz J. Evidence for a neuromodulatory role of GABA at the first synapse of the baroreceptor reflex pathway. Effects of GABA derivatives injected into the NTS. Naunyn Schmiedebergs Arch Pharmacol 319: 168-171, 1982.
6. 9-trans-tetrahydrocannabinol in anesthetized dogs. Eur J Pharmacol 22: 263-269, 1973.
7. 9-trans-tetrahydrocannabinol in anesthetized dogs. Res Commun Chem Pathol Pharmacol 6: 526-540, 1973.
8. Chen CY and Bonham AC. Non-NMDA and NMDA receptors transmit area postrema input to aortic baroreceptor neurons in NTS. Am J Physiol Heart Circ Physiol 275: H1695-H1706, 1998.
9. Cuello C and Kanazawa I. The distribution of substance P immunoreactive fibers in the rat central nervous system. J Comp Neurol 178: 129-136, 1978.
10. 1. J Comp Neurol 422: 159-171, 2000.
11. B receptor activation in the nucleus tractus solitarii of the rat. Brain Res 535: 264-270, 1990.
12. 1 cannabinoid receptor inhibits synaptic release of glutamate in rat dorsolateral striatum. J Neurophysiol 85: 468-471, 2001.
13. 1 receptor binding and mRNA levels. Drug Alcohol Depend 66: 77-84, 2002.
14. Hajos N, Katona I, Naiem SS, Mackie K, Ledent C, Mody I, and Freund TF. Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations. Eur J Neurosci 12: 3239-3249, 2000.
15. Hajosa N, Ledent C, and Freund TF. Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus. Neuroscience 106: 14, 2001.
16. Hardman HF, Domino EF, and Seevers MH. General pharmacological actions of some synthetic tetrahydrocannabinol derivatives. Pharmacol Rev 23: 295-315, 1971.
17. Head GA. Baroreflexes and cardiovascular regulation in hypertension. J Cardiovasc Pharmacol 26: S7-S16, 1995.
18. Hillard CJ. Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. Prostagladins Other Lipid Mediat 61: 3-18, 2000.
19. Hillard CJ and Jarrahian A. The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes. Chem Phys Lipids 108: 123-134, 2000.
20. Himmi T, Perrin J, Ouazzani TE, and Orsini JC. Neuronal responses to cannabinoid receptor ligands in the solitary tract nucleus. Eur J Pharmacol 359: 49-54, 1998.
21. A synaptic transmission in the hippocampus. J Neurosci 20: 2470-2479, 2000.
22. Huang CC, Lo SW, and Hsu KS. Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons. J Physiol 532: 731-748, 2001.
23. Jones RT. Cardiovascular system effects of marijuana. J Clin Pharmacol 42: 58S-63S, 2002.
24. Katona I, Sperlagh B, Magloczky Z, Santha E, Kofalvi A, Czirjak S, Mackie K, Vizi ES, and Freund TF. GABAergic interneurons are the targets of cannabinoid actions in the human hippocampus. Neuroscience 100: 797-804, 2000.
25. Lake KD, Martin BR, Kunos G, and Varga K. Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. Hypertension 29: 1204-1210, 1997.
26. Levenes C, Daniel H, Soubrie P, and Crepel F. Cannabinoids decrease excitatory synaptic transmission and impair long-term depression in rat cerebellar Purkinje cells. J Physiol 510: 867-879, 1998.
27. Manzoni OJ and Bockaert J. Cannabinoids inhibit GABAergic synaptic transmission in mice nucleus accumbens. Eur J Pharmacol 412: R3-R5, 2001.
28. McWilliam PN and Shepheard SL. A GABA-mediated inhibition of neurones in the nucleus tractus solitarius of the cat that respond to electrical stimulation of the carotid sinus nerve. Neurosci Lett 94: 321-326, 1988.
29. 9-tetrahydrocannabinol in the spontaneously hypertensive rat. Proc Soc Exp Biol Med 142: 58-60, 1973.
30. Niederhoffer N and Szabo B. Cannabinoids cause central sympathoexcitation and bradycardia in rabbits. J Pharmacol Exp Ther 294: 707-713, 2000.
31. Okada M and Bunag RD. Contrasting baroreflex effects of muscimol versus bicuculline injected into the nucleus tractus solitarius in anesthetized rats. J Cardiovasc Pharmacol 26: 363-371, 1995.
32. Patel S, Rademacher DJ, and Hillard CJ. Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity. J Pharmacol Exp Ther 306: 880-888, 2003.
33. Rademacher DJ, Patel S, Hopp FA, Dean C, Hillard CJ, and Seagard JL. Microinjection of a cannabinoid receptor antagonist into the NTS increases baroreflex duration in dogs. Am J Physiol Heart Circ Physiol 284: H1570-H1576, 2003.
34. Schlicker E and Kathmann M. Modulation of transmitter release via presynaptic cannabinoid receptors. Trends Pharmacol Sci 22: 565-572, 2001.
35. Seagard JL, Dean C, and Hopp FA. Activity-dependent role of NMDA receptors in transmission of cardiac mechanoreceptor input to the NTS. Am J Physiol Heart Circ Physiol 284: H884-H891, 2003.
36. Stark P and Dews PB. Cannabinoids. II. Cardiovascular effects. J Pharmacol Exp Ther 214: 131-138, 1980.
37. Stella N and Piomelli D. Receptor-dependent formation of endogenous cannabinoids in cortical neurons. Eur J Pharmacol 425: 189-196, 2001.
38. Sullivan JM. Mechanisms of cannabinoid-receptor-mediated inhibition of synaptic transmission in cultured hippocampal pyramidal neurons. J Neurophysiol 82: 1286-1294, 1999.
39. Sved AF. GABA-mediated neural transmission in mechanisms of cardiovascular control. In: Nucleus of the Solitary Tract, edited by Barraco IRA. Boca Raton, FL: CRC, 1994, p. 245-254.
40. B receptors in the nucleus tractus solitarius modulates the baroreceptor reflex. Brain Res 592: 37-43, 1992.
41. Sweazey RD. Distribution of aspartate and glutamate in the nucleus of the solitary tract of the lamb. Exp Brain Res 105: 241-253, 1995.
42. Szabo B, Dorner L, Pfreundtner C, Norenberg W, and Starke K. Inhibition of GABAergic inhibitory postsynaptic currents by cannabinoids in rat corpus striatum. Neuroscience 85: 395-403, 1998.
43. Szabo B, Wallmichrath I, Mathonia P, and Pfreundtner C. Cannabinoids inhibit excitatory neurotransmission in the substantia nigra pars reticulata. Neuroscience 97: 87-97, 2000.
44. Takahashi KA and Linden DJ. Cannabinoid receptor modulation of synapses received by cerebellar Purkinje cells. J Neurophysiol 83: 1167-1180, 2000.
45. Talman WT, Perrone MH, and Reis DJ. Evidence for L-glutamate as the neurotransmitter of baroreceptor afferent fibers. Science 209: 813-815, 1980.
46. Ueda N, Puffenbarger RA, Yamamoto S, and Deutsch DG. The fatty acid amide hydrolase (FAAH). Chem Phys Lipids 108: 107-121, 2000.
47. 1 cannabinoid receptor in the hypotensive action of anandamide. Eur J Pharmacol 278: 279-283, 1995.
48. Varga K, Lake KD, Huangfu D, Guyenet PG, and Kunos G. Mechanism of the hypotensive action of anandamide in anesthetized rats. Hypertension 28: 682-686, 1996.
49. Vaughan CW, Connor M, Bagley EE, and Christie MJ. Actions of cannabinoids on membrane properties and synaptic transmission in rat periaqueductal gray neurons in vitro. Mol Pharmacol 57: 288-295, 2000.
50. Vaughan CW, McGregor IS, and Christie MJ. Cannabinoid receptor activation inhibits GABAergic neurotransmission in rostral ventromedial medulla neurons in vitro. Br J Pharmacol 127: 935-940, 1999.
51. 8-tetrahydrocannabinol-dimethylheptyl in rats. J Cardiovasc Pharmacol 28: 332-336, 1996.
52. B receptor-mediated responses in the nucleus tractus solitarius are altered in acute and chronic hypertension. Hypertension 37: 619-622, 2001.
53. 9-trans-tetrahydocannabinol. J Pharm Pharmacol 26: 186-192, 1974.
54. Zhang J and Mifflin SW. Receptor subtype-specific effects of GABA agonists on neurons receiving aortic depressor nerve inputs within the nucleus of the solitary tract. J Auton Nerv Syst 10: 170-181, 1998.