Transforming growth factor-β1 accelerates bone bonding to a blended calcium phosphate ceramic coating: A dose-response study

Journal of Biomedical Materials Research - Part A

Volumn 68, Issue 3, 2004, Pages 537-543

  Szivek, John A ^a   Nelson, Ehren R ^a   Hajdu, Steven D ^a   Yablonski, Kelly ^a   DeYoung, Don W ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Calcium phosphate ceramics (CPC); Dose response; In vivo strain analysis; Strain gauge; Transforming growth factor (TGF) 1

Indexed keywords

BONE; CALCIUM COMPOUNDS; DRUG DOSAGE; ELECTRON MICROSCOPY;

BACK SCATTERED ELECTRON MICROSCOPY; CALCIUM PHOSPHATE CERAMIC (CPE);

BIOMATERIALS;

CALCIUM PHOSPHATE CERAMIC; POLYSULFONE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BONE BONDING; BONE GROWTH; BONE REMODELING; CONTROLLED STUDY; DOG; DOSE RESPONSE; ELECTRON MICROSCOPY; EXERCISE; FEMUR; IN VIVO STUDY; MATERIAL COATING; NONHUMAN; OSSIFICATION; STRAIN GAUGE TRANSDUCER; STRESS STRAIN RELATIONSHIP; WEIGHT BEARING;

EID: 1342301646     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.a.20099     Document Type: Article

References (18)

1. Lanyon LE. Strain in sheep lumbar vertebrae recorded during life. Acta Orthop Scand 1971;42:102-112.
2. Lanyon LE, Smith RN. Bone strain in the tibia during normal quadrupedal locomotion. Acta Orthop Scand 1970;41:238-248.
3. Keller TS, Spengler DM. In Vivo strain gauge implantation in rats. J Biomech 1982;15(12):911-917.
4. Cameron JJ, Boodward SC, Pulaski EJ, Sleeman HK, Brandes G, Kulkarni RK, Leonard F. The degradation of cyanoacrylate tissue adhesives. Surgery 1965;58:424-430.
5. Leonard F, Kulkarni RK, Brandes G, Nelson J, Cameron JJ. Synthesis and degradation of poly (alkylalphacyanoacrylates). J Appl Polym Sci 1966;10:259-272.
6. Szivek JA, DeYoung DW, Anderson PL. In Vivo strain measurements collected using calcium phosphate ceramic-bonded strain gauges. J Invest Surg 1997;10(5):263-273.
7. Rabkin BA, Szivek JA, Schonfeld JE, Halloran BP. Long-term measurement of bone strain in vivo: The rat tibia. J Biomed Mater Res 2001;58(3):277-281.
8. Szivek JA, Anderson PL, Wilson DL, DeYoung DW. Development of a model for study of in vivo bone strains in normal and microgravity environments. J Appl Biomater 1995;6:203-208.
9. Szivek JA, Anderson PL, Dishongh TJ, DeYoung DW. Evaluation of factors affecting bonding rate of calcium phosphate ceramic coatings for in vivo strain gauge attachment. J Biomed Mater Res 1996;33:121-132.
10. Cordaro NM, Szivek JA, DeYoung DW. Surface enhancements accelerate bone bonding to CPC coated strain gauges. J Biomed Mater Res 2001;56:109-119.
11. Becton Dickinson Laboratory product specification sheet. Human transforming growth factor β-1. Bedford, MA; 1996.
12. Sumner DR, Turner TM, Gombotz WR, Urban RM, Galante JO. Enhancement of bone in-growth by TGF-β. J Bone Joint Surg 1995;77:1135-1147.
13. Maliniak MN, Szivek JA, DeYoung DW, Emmanual J. HA coated strain gauges for long term in vivo bone strain measurements. J Appl Biomater 1993;4:143-152.
14. Kersey RC, Szivek JA, Sacoman DM. Technical note. Symmetry of biomechanical properties in canine femora. J Appl Biomater 1994;5:99-101.
15. Battraw GA, Szivek JA, Anderson PL. Bone bonding strength of CPC coated strain gauges. J Biomed Mater Res 1999;44:32-35.
16. Battraw GA, Szivek JA, Anderson PL. Interface strength study of CPC strain gauges. J Biomed Mater Res 1998;43:462-468.
17. Szivek JA, Johnson EM, Magee FP. In vivo strain analysis of the greyhound femoral diaphysis. J Invest Surg 1992;5:91-108.
18. Ong JL, Carnes DL, Sogal S. Effect of transforming growth factor-β on osteoblast cells cultured on 3 different hydroxyapatite surfaces. Int J Oral Maxillofac Implants 1999;14:217-225.