Augmentation of the Development of Behavioral Tolerance to Cannabinoid Administration through Pavlovian Conditioning

Neuropsychobiology

Volumn 49, Issue 2, 2004, Pages 94-100

  Hill, Matthew N ^a   Gorzalka, Boris B ^a   Choi, Joyce W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cannabinoid; HU 210; Pavlovian conditioning; Tolerance; Withdrawal

Indexed keywords

CANNABINOID RECEPTOR AGONIST; DEXANABINOL; PLACEBO;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDITIONED REFLEX; CONTROLLED STUDY; DRUG EFFECT; DRUG TOLERANCE; FEMALE; INSTRUMENTAL CONDITIONING; LOCOMOTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES COMPARISON; STATE DEPENDENT LEARNING; WITHDRAWAL REFLEX;

ANIMALS; BEHAVIOR, ANIMAL; CANNABINOIDS; CONDITIONING, CLASSICAL; DRUG TOLERANCE; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; MOTOR ACTIVITY; PLACEBOS; RANDOM ALLOCATION; RATS; TETRAHYDROCANNABINOL; TIME FACTORS;

EID: 1342291014     PISSN: 0302282X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000076417     Document Type: Article

References (28)

1. Gaoni Y, Mechoulam R: Isolation, structure and partial synthesis of an active constituent of hashish. J Am Chem Soc 1964;86:1646-1647.
2. Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI: Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 1990;346:561-564.
3. 2 receptors. Pharmacol Ther 1997;74:129-180.
4. Herkenham M, Lynn AB, Little MD, Johnson MR, Melvin LS, de Costa BR, Rice KC: Cannabinoid receptor localization in the brain. Proc Natl Acad Sci USA 1990;87:1932-1936.
5. Munro S, Thomas KL, Abu-Shaar M: Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993;365:61-65.
6. Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, Gibson D, Mandelbaum A, Etinger A, Mechoulam R: Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 1992;258:1946-1949.
7. 8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor. Neuropharmacology 1990;29:161-165.
8. Ottani A, Giulianni D: HU-210: A potent tool for investigations of the cannabinoid system. CNS Drug Rev 2001;7:131-145.
9. 8-THC-dimethylheptyl in mice and dogs. Pharmacol Biochem Behav 1989;32:661-666.
10. Dewey WL: Cannabinoid pharmacology. Pharmacol Rev 1986;38:151-178.
11. Rodriguez de Fonesca F, Gorriti MA, Fernandez-Ruiz JJ, Palomo T, Ramos JA: Downregulation of rat cannabinoid binding sites after chronic delta 9-tetrahydrocannabinol treatment. Pharmacol Biochem Behav 1994;47:33-40.
12. Romero J, Berrendero F, Manzaneres J, Perez A, Corchero J, Fuentes JA, Fernandez-Ruiz JJ, Ramos JA: Time course of the cannabinoid receptor down-regulation in the adult rat brain caused by repeated exposure to delta9-tetrahydrocannabinol. Synapse 1998;30:298-308.
13. Zhuang S, Kittler J, Grigorenko EV, Kirby MT, Sim LJ, Hampson RE, Childers SR, Deadwyler SA: Effects of long-term exposure to delta9-THC on expression of cannabinoid receptor (CB1) mRNA in different rat brain regions. Brain Res Mol Brain Res 1998;62:141-149.
14. Abood ME, Sauss C, Fan F, Tilton CL, Martin BR: Development of behavioral tolerance to delta9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain. Pharmacol Biochem Behav 1993;46:575-579.
15. Rubino T, Massi P, Patrini G, Venier I, Giagnoni G, Parolaro D: Chronic CP-55,940 alters cannabinoid receptor mRNA in the rat brain: An in situ hybridization study. Neuroreport 1994;5:2493-2496.
16. Siegel S, MacRae J: Environmental specificity of tolerance. Trends Neurosci 1984;7:140-143.
17. Smith JB: Situational specificity of tolerance to decreased operant responding by morphine and 1-nantradol. Psychopharmacology 1991;103:115-120.
18. Ten Ham M: Tolerance to the effects of delta9-THC on shuttle box performance and body temperature. Pharmacol Biochem Behav 1977;6:183-185.
19. Costa B, Giagnoni G, Colleoni M: Precipitated and spontaneous withdrawal in rats tolerant to anandamide. Psychopharmacology 2000;149:121-128.
20. Gonzalez S, Bisogno T, Wenger T, Manzaneres J, Milone A, Berrendero F, DiMarzo V, Ramos JA, Fernandez-Ruiz JJ: Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. Biochem Biophys Res Commun 2000;270:260-266.
21. Valle FP, Gorzalka BB: Open field sex differences prior to puberty in rats. Bull Psychonom Soc 1980;16:429-431.
22. 1- tetrahydrocannabinol and other cannabinoids with emphasis on man. Pharmacol Rev 1986;38:21-43.
23. Creasey WA: Drug Disposition in Humans. New York, Oxford University Press, 1979.
24. Ameri A: The effects of cannabinoids on the brain. Prog Neurobiol 1999;58:315-348.
25. DiMarzo V, Berrendero F, Bisogno T, Gonzalez S, Cavaliere P, Romero J, Cebeira M, Ramos JA, Fernandez-Ruiz JJ: Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of delta9-tetrahydrocannabinol-tolerant rats. J Neurochem 2000;74:1627-1635.
26. Glass M, Brotchie JM, Maneuf YP: Modulation of neurotransmission by cannabinoids in the basal ganglia. Eur J Neurosci 1997;9:199-203.
27. DiMarzo V, Melck D, Bisogno T, De Petrocellis L: Endocannabinoids: Endogenous cannabinoid receptor ligands with neuromodulatory action. Trends Neurosci 1998;21:521-528.
28. Schultz W, Dayan P, Montague PR: A neural substrate of prediction and reward. Science 1997;275:1593-1599.