Lipoic Acid-Dependent Oxidative Catabolism of α-Keto Acids in Mitochondria Provides Evidence for Branched-Chain Amino Acid Catabolism in Arabidopsis

Plant Physiology

Volumn 134, Issue 2, 2004, Pages 838-848

  Taylor, Nicolas L ^a   Heazlewood, Joshua L ^a   Day, David A ^a   Millar, A Harvey ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CROPS; DETOXIFICATION; ENZYMES; MASS SPECTROMETRY; OXIDATION;

CATABOLISM; MITOCHRONDRIA;

PLANTS (BOTANY);

ARABIDOPSIS; ORYZA SATIVA; PISUM; PISUM SATIVUM;

EID: 1342287231     PISSN: 00320889     EISSN: None     Source Type: Journal    
DOI: 10.1104/pp.103.035675     Document Type: Article

References (45)

1. Anderson MD, Che P, Song J, Nikolau BJ, Wurtele ES (1998) 3-Methylcrotonyl-coenzyme A carboxylase is a component of the mitochondrial leucine catabolic pathway in plants. Plant Physiol 118: 1127-1138
2. Aubert S, Alban C, Bligny R, Douce R (1996) Induction of beta-methylcrotonyl-coenzyme A carboxylase in higher plant cells during carbohydrate starvation: evidence for a role of MCCase in leucine catabolism. FEBS Lett 383: 175-180
3. Che P, Wurtele ES, Nikolau BJ (2002) Metabolic and environmental regulation of 3-methylcrotonyl-coenzyme A carboxylase expression in Arabidopsis. Plant Physiol 129: 625-637
4. Chew O, Whelan J (2003) Dual targeting ability of targeting signals is dependent on the nature of the mature protein. Funct Plant Biol 30: 805-812
5. Daschner K, Couee I, Binder S (2001) The mitochondrial isovaleryl-coenzyme A dehydrogenase of Arabidopsis oxidizes intermediates of leucine and valine catabolism. Plant Physiol 126: 601-612
6. Diebold R, Schuster J, Daschner K, Binder S (2002) The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins. Plant Physiol 129: 540-550
7. Dieuaide M, Couee I, Pradet A, Raymond P (1993) Effects of glucose starvation on the oxidation of fatty acids by maize root tip mitochondria and peroxisomes: evidence for mitochondrial fatty acid beta-oxidation and acyl-CoA dehydrogenase activity in a higher plant. Biochem J 296: 199-207
8. Dry IB, Wiskich JT (1987) 2-Oxoglutarate dehydrogenase and pyruvate dehydrogenase activities in plant mitochondria interaction via a common coenzyme A pool. Arch Biochem Biophys 257: 92-99
9. Eden A, Benvenisty N (1999) Involvement of branched-chain amino acid aminotransferase (Bcat1/Eca39) in apoptosis. FEBS Lett 457: 255-261
10. Fujiki Y, Ito M, Itoh T, Nishida I, Watanabe A (2002) Activation of the promoters of Arabidopsis genes for the branched-chain alpha-keto acid dehydrogenase complex in transgenic tobacco BY-2 cells under sugar starvation. Plant Cell Physiol 43: 275-280
11. Fujiki Y, Ito M, Nishida I, Watanabe A (2001) Leucine and its keto acid enhance the coordinated expression of genes for branched-chain amino acid catabolism in Arabidopsis under sugar starvation. FEBS Lett 499: 161-165
12. Fujiki Y, Sato T, Ito M, Watanabe A (2000) Isolation and characterization of cDNA clones for the E1β and E2 subunits of the branched-chain α-ketoacid dehydrogenase complex in Arabidopsis. J Biol Chem 275: 6007-6013
13. Gerhardt B (1992) Fatty acid degradation in plants. Prog Lipid Res 31: 417-446
14. Germain V, Rylott EL, Larson TR, Sherson SM, Bechtold N, Carde JP, Bryce JH, Graham IA, Smith SM (2001) Requirement for 3-ketoacyl-CoA thiolase-2 in peroxisome development, fatty acid beta-oxidation and breakdown of triacylglycerol in lipid bodies of Arabidopsis seedlings. Plant J 28: 1-12
15. Graham IA, Eastmond PJ (2002) Pathways of straight and branched chain fatty acid catabolism in higher plants. Prog Lipid Res 41: 156-181
16. Heazlewood JL, Howell KA, Whelan J, Millar AH (2003) Towards the analysis of the rice mitochondrial proteome. Plant Physiol 132: 230-242
17. Heazlewood JL, Tonti-Filippini JS, Gout AM, Day DA, Whelan JM, Millar AH (2004) Experimental analysis of the Arabidopsis mitochondrial proteome highlights signalling and regulatory components, provides assessment of targeting prediction programs and points to plant specific mitochondrial proteins. Plant Cell 16: 241-256
18. Johnston ML, Luethy MH, Miernyk JA, Randall DD (1997) Cloning and molecular analyses of the Arabidopsis thaliana plastid pyruvate dehydrogenase subunits. Biochim Biophys Acta 1321: 200-206
19. Jones SM, Yeaman SJ (1986) Oxidative decarboxylation of 4-methylthio-2-oxobutyrate by branched-chain 2-oxo acid dehydrogenase complex. Biochem J 237: 621-623
20. Kruft V, Eubel H, Jansch L, Werhahn W, Braun HP (2001) Proteomic approach to identify novel mitochondrial proteins in Arabidopsis. Plant Physiol 127: 1694-1710
21. Lawand S, Dorne AJ, Long D, Coupland G, Mache R, Carol P (2002) Arabidopsis A BOUT DE SOUFFLE, which is homologous with mammalian carnitine acyl carrier, is required for postembryonic growth in the light. Plant Cell 14: 2161-2173
22. Lawson JE, Behal RH, Reed LJ (1991) Disruption and mutagenesis of the Saccharomyces cerevisiae PDX1 gene encoding the protein X component of the pyruvate dehydrogenase complex. Biochemistry 30: 2834-2839
23. Lutziger I, Oliver DJ (2001) Characterization of two cDNAs encoding mitochondrial lipoamide dehydrogenase from Arabidopsis. Plant Physiol 127: 615-623
24. Masterson C, Wood C (2001) Mitochondrial and peroxisomal beta-oxidation capacities of organs from a non-oilseed plant. Proc R Soc Lond B Biol Sci 268: 1949-1953
25. Miernyk JA, Thomas DR, Wood C (1991) Partial purification and characterisation of the mitochondrial and peroxisomal isozymes of enoylcoenzyme A hydratase from germinating pea seedlings. Plant Physiol 95: 564-569
26. Millar AH, Hill SA, Leaver CJ (1999a) Plant mitochondrial 2-oxoglutarate dehydrogenase complex: purification and characterization in potato. Biochem J 343: 327-334
27. Millar AH, Leaver CJ, Hill SA (1999b) Characterization of the dihydrolipoamide acetyltransferase of the mitochondrial pyruvate dehydrogenase complex from potato and comparisons with similar enzymes in diverse plant species. Eur J Biochem 264: 973-981
28. Millar AH, Sweetlove LJ, Giege P, Leaver CJ (2001) Analysis of the Arabidopsis mitochondrial proteome. Plant Physiol 127: 1711-1727
29. Mooney BP, Henzl MT, Miernyk JA, Randall DD (2000) The dihydrolipoyl acyltransferase (BCE2) subunit of the plant branched-chain alpha-ketoacid dehydrogenase complex forms a 24-mer core with octagonal symmetry. Protein Sci 9: 1334-1339
30. Mooney BP, Miernyk JA, Randall DD (1998) Nucleotide sequence of a cDNA encoding the E1α subunit of the branched chain a-keto acid dehydrogenase complex from Arabidopsis thaliana (accession no. AF077955) (PGR98-168). Plant Physiol 118: 711
31. Mooney BP, Miernyk JA, Randall DD (2002) The complex fate of alpha-ketoacids. Annu Rev Plant Biol 53: 357-375
32. Ogier de Baulny H, Saudubray JM (2002) Branched-chain organic acidurias. Semin Nenatol 7: 65-74
33. Peeters N, Small I (2001) Dual targeting to mitochondria and chloroplasts. Biochim Biophys Acta 1541: 54-63
34. Perham RN, Jones DD, Chauhan HJ, Howard MJ (2002) Substrate channelling in 2-oxo acid dehydrogenase multienzyme complexes. Biochem Soc Trans 30: 47-51
35. Poulsen LL, Wedding RT (1970) Purification and properties of the alpha-ketoglutarate dehydrogenase complex of cauliflower mitochondria. J Biol Chem 245: 5709-5717
36. Randall DD, Rubin PM, Fenko M (1977) Plant pyruvate dehydrogenase complex purification, characterization and regulation by metabolites and phosphorylation. Biochim Biophys Acta 485: 336-349
37. Reed LJ (1974) Multienzyme complexes. Ace Chem Res 7: 40-46
38. Reed LJ (1981) Regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle. Curr Top Cell Regul 18: 95-106
39. Schuldiner O, Eden A, Ben-Yosef T, Yanuka O, Simchen G, Benvenisty N (1996) ECA39, a conserved gene regulated by c-Myc in mice, is involved in G1/S cell cycle regulation in yeast. Proc Natl Acad Sci USA 93: 7143-7148
40. Sweetlove LJ, Heazlewood JL, Herald V, Holtzapffel R, Day DA, Leaver CJ, Millar AH (2002) The impact of oxidative stress on Arabidopsis mitochondria. Plant J 32: 891-904
41. Taylor NL, Day DA, Millar AH (2002) Environmental stress causes oxidative damage to plant mitochondria leading to inhibition of glycine decarboxylase. J Biol Chem 277: 42663-42668
42. Thelen JJ, Muszynski MG, David NR, Luethy MH, Elthon TE, Miernyk JA, Randall DD (1999) The dihydrolipoamide S-acetyltransferase subunit of the mitochondrial pyruvate dehydrogenase complex from maize contains a single lipoyl domain. J Biol Chem 274: 21769-21775
43. Tsukamoto T, Hata S, Yokota S, Miura S, Fujiki Y, Hijikata M, Miyazawa S, Hashimoto T, Osumi T (1994) Characterization of the signal peptide at the amino terminus of the rat peroxisomal 3-ketoacyl-CoA thiolase precursor. J Biol Chem 269: 6001-6010
44. Yeaman SJ (1989) The 2-oxo acid dehydrogenase complexes: recent advances. Biochem J 257: 625-632
45. Zolman BK, Monroe-Augustus M, Thompson B, Hawes JW, Krukenberg KA, Matsuda SP, Bartel B (2001) chy1, an Arabidopsis mutant with impaired β-oxidation, is defective in a peroxisomal beta-hydroxyisobutyryl-CoA hydrolase. J Biol Chem 276: 31037-31046