Parabrachial neurons mediate dorsal periaqueductal gray evoked respiratory responses in the rat

Journal of Applied Physiology

Volumn 96, Issue 3, 2004, Pages 1146-1154

  Hayward, Linda F ^a   Castellanos, Mabelin ^a   Davenport, Paul W ^a  

^a University of Florida College of Veterinary Medicine   (United States)

Author keywords

Control of breathing; Dorsal periaqueductal gray; Hypertension; Hyperventilation; Lateral parabrachial nucleus

Indexed keywords

GLUTAMATE RECEPTOR ANTAGONIST; KYNURENIC ACID; MUSCIMOL; URETHAN;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN NERVE CELL; BRAIN REGION; BREATHING; BREATHING RATE; CELL ACTIVATION; CELL FUNCTION; CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTROSTIMULATION; EVOKED RESPONSE; EXHALATION; HEART RATE; INHALATION; MALE; MEDULLA OBLONGATA; NERVE CONDUCTION; NERVE PROJECTION; NONHUMAN; PARABRACHIAL NUCLEUS; PARAMETER; PERIAQUEDUCTAL GRAY MATTER; PONS; PRIORITY JOURNAL; RAT; RAT STRAIN; RECEPTOR BLOCKING;

ANIMALS; BLOOD PRESSURE; BRACHIAL PLEXUS; EVOKED POTENTIALS; HEART RATE; MALE; MUSCIMOL; PERIAQUEDUCTAL GRAY; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY MECHANICS;

EID: 1342283029     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00903.2003     Document Type: Article

References (46)

1. Bandler R, Keay KA, Floyd N, and Price J. Central circuits mediating patterned autonomic activity during active vs. passive emotional coping. Brain Res Bull 53: 95-104, 2000.
2. Bandler R, Prineas S, and McCulloch B. Further localization of midbrain neurones mediating the defense reaction in the cat by microinjections of excitatory amino acids. Neurosci Lett 56: 311-316, 1985.
3. Bandler R and Shipley MT. Columnar organization in the midbrain periaqueductal gray: modules for emotional expression? Trends Neurosci 17: 379-389, 1994.
4. Bandler R and Tork I. Midbrain periaqueductal grey region in the cat has afferent and efferent connections with solitary tract nuclei. Neurosci Lett 74: 1-6, 1987.
5. Bassal M and Bianchi AL. Inspiratory onset or termination induced by electrical stimulation of the brain. Respir Physiol 50: 23-40, 1982.
6. Behbehani M. Functional characteristics of the midbrain periaqueductal gray. Prog Neurobiol 46: 575-605, 1995.
7. Brandao M, Anseloni VZ, Pandossio JE, De Araujo JE, and Castilho VM. Neurochemical mechanisms of defensive behavior in the dorsal midbrain. Neurosci Biobehav Rev 23: 863-875, 1999.
8. Carrive P and Bandler R. Control of extracranial and hindlimb blood flow by the periaqueductal grey of the cat. Exp Brain Res 84: 599-606, 1991.
9. Carrive P and Bandler R. Viscerotopic organization of neurons subserving hypotensive reactions within the midbrain periaqueductal grey: a correlative functional and anatomical study. Brain Res 541: 206-215, 1991.
10. Carrive P, Bandler R, and Dampney RAL. Viscerotopic control of regional vascular beds by discrete groups of neurons within the midbrain periaqueductal gray. Brain Res 493: 385-390, 1989.
11. Chamberlin NL and Saper CB. Topographic organization of cardiovascular responses to electrical and glutamate microstimulation of the parabrachial nucleus of the rat. J Comp Neurol 326: 245-262, 1992.
12. Chamberlin NL and Saper CB. Topographical organization of respiratory responses to glutamate microstimulation of the parabrachial nucleus in the rat. J Neurosci 14: 6500-6510, 1994.
13. Darlington DN and Ward DG. Rostral pontine and caudal mesencephalic control of arterial pressure and iliac, celiac, and renal vascular resistance. I. Anatomic regions. Brain Res 361: 284-300, 1985.
14. Farkas E, Jansen ASP, and Loewy AD. Periaqueductal gray matter projection to vagal preganglionic neurons and the nucleus tractus solitarius. Brain Res 764: 257-261, 1997.
15. Farkas E, Jansen ASP, and Loewy AD. Periaqueductal gray matter input to cardiac-related sympathetic premotor neurons. Brain Res 792: 179-192, 1998.
16. Fendt M. Differential regions of the periaqueductal gray are involved in the expression and conditioned inhibition of fear-potentiated startle. Eur J Neurosci 10: 3876-3884, 1998.
17. Fontes M, Tagawa T, Polson JW, Cavanagh SJ, and Dampney RAL. Descending pathways mediating cardiovascular response from dorsomedial hypothalamic nucleus. Am J Physiol Heart Circ Physiol 280: H2891-H2901, 2001.
18. Fung ML and St. John WM. Separation of multiple functions in ventilatory control of pneumotaxic mechanisms. Respir Physiol 96: 83-98, 1994.
19. Fung ML, Wang W, and St. John WM. Involvement of pontile NMDA receptors in inspiratory termination in rat. Respir Physiol 96: 177-188, 1994.
20. 2-adrenoreceptor modulation of arterial chemoreflex in the caudal solitary nucleus of the rat. Am J Physiol Regul Integr Comp Physiol 281: R1464-R1473, 2001.
21. Hayward L and Castellanos M. Increased Fos expression in select lateral parabrachial subnuclei following chemical versus electrical stimulation of the dorsal periaqueductal gray in rats. Brain Res 974: 153-166, 2003.
22. Hayward L, Swartz CL, and Davenport PW. Respiratory response to activation or disinhibition of the dorsal periaqueductal gray in rats. J Appl Physiol 94: 913-922, 2003.
23. Hayward LF and Felder RB. Lateral parabrachial nucleus modulates baroreflex regulation of sympathetic activity. Am J Physiol Regul Integr Comp Physiol 274: R1274-R1282, 1998.
24. Holstege G, Kerstens L, Moes MC, and Vanderhorst VGJM. Evidence for a periaqueductal gray-nucleus retroambiguus-spinal cord pathway in the rat. Neuroscience 80: 587-598, 1997.
25. Huang ZG, Subramanian SH, Balnave RJ, Turman AB, and Chow CM. Roles of periaqueductal gray and nucleus tractus solitarius in cardiorespiratory function in the rat brainstem. Respir Physiol 120: 185-195, 2000.
26. Jansen A, Farkas E, Sams JM, and Loewy AD. Local connections between the columns of the periaqueductal gray matter: a case for intrinsic neuromodulation. Brain Res 784: 329-336, 1998.
27. Krout K, Jansen ASP, and Loewy AD. Periaqueductal gray matter projection to the parabrachial nucleus in rat. J Comp Neurol 401: 437-454, 1998.
28. Lara JP, Parkes MJ, Silva-Carvhalo L, Izzo P, Dawid-Milner MS, and Spyer KM. Cardiovascular and respiratory effects of stimulation of cell bodies of the parabrachial nuclei in the anesthetized rat. J Physiol 477: 321-329, 1994.
29. Len W and Chan JY. GABAergic neurotransmission at the nucleus tractus solitarii in the suppression of reflex bradycardia by parabrachial nucleus. Synapse 42: 27-39, 2001.
30. Len W, Chan SH, and Chan JY. Parabrachial nucleus induces suppression of baroreflex bradycardia by the release of glutamate in the rostral ventrolateral medulla of the rat. J Biomed Sci 7: 401-411, 2000.
31. Ling L, Karius DR, and Speck DF. Role of N-methyl-D-aspartate receptors in the pontine pneumotaxic mechanism in the cat. J Appl Physiol 76: 1138-1143, 1994.
32. Lovick T. Inhibitory modulation of cardiovascular defense response by the ventrolateral periaqueductal gray matter in rats. Exp Brain Res 89: 133-139, 1992.
33. Lovick T. Integrated activity of cardiovascular and pain regulatory systems: role in adaptive behavioral responses. Prog Neurobiol 40: 631-644, 1993.
34. Lui K, Solomon NP, and Luschei ES. Midbrain regions for eliciting vocalization by electrical stimulation in anesthetized dogs. Ann Otol Rhinol Laryngol 107: 977-986, 1998.
35. Miura M and Takayama K. Circulatory and respiratory responses to glutamate stimulation of the lateral parabrachial nucleus of the cat. J Auton Nerv Syst 32: 121-134, 1991.
36. Mraovitch S, Kumada M, and Reis DJ. Role of the nucleus parabrachialis in cardiovascular regulation in cat. Brain Res 232: 57-75, 1982.
37. Nakai M and Maeda M. Systemic and regional haemodynamic responses elicited by microinjection of N-methyl-D-aspartate into the lateral periaqueductal gray matter in anesthetized rats. Neuroscience 58: 777-783, 1994.
38. Nosaka S, Murata K, Inui K, and Murase S. Arterial baroreflex inhibition by midbrain periaqueductal grey in anesthetized rats. Pflügers Arch 424: 266-275, 1993.
39. Nosaka SI, Murata K, Murase S, and Murata K. A prejunctional mechanism in midbrain periaqueductal gray inhibition of vagal bradycardia in rats. Am J Physiol Regul Integr Comp Physiol 270: R373-R382, 1996.
40. Paxinos G and Watson C. The Rat Brain in Stereotaxic Coordinates. New York: Academic, 1998.
41. Saleh TM and Connell BJ. Modulation of the cardiac baroreflex following reverse blockade of the parabrachial nucleus in the rat. Brain Res 767: 201-207, 1997.
42. St. John W. Neurogenesis of patterns of automatic ventilatory activity. Prog Neurobiol 56: 97-117, 1998.
43. Van Der Plas J, Maes FW, and Bohus B. Electrophysiological analysis of midbrain periaqueductal gray influence on cardiovascular neruons in the ventrolateral medulla oblongata. Brain Res Bull 38: 447-456, 1995.
44. Verberne AJ and Guyenet PG. Midbrain central gray: influence on medullary sympathoexcitatory neurons and the baroreflex in rats. Am J Physiol Regul Integr Comp Physiol 263: R24-R33, 1992.
45. Zhang S, Davis PJ, Bandler R, and Carrive P. Brainstem integration of vocalization: role of the midbrain periaqueductal gray. J Neurophysiol 72: 1337-1356, 1994.
46. Zidichouski JA and Jhamandas JH. Electrophysiological characterization of excitatory amino acid responses in rat lateral parabrachial neurons in vitro. Brain Res 611: 313-321, 1994.