Periaqueductal gray matter input to cardiac-related sympathetic premotor neurons

Brain Research

Volumn 792, Issue 2, 1998, Pages 179-192

  Farkas, Eszter ^a   Jansen, Arthur S P ^a   Loewy, Arthur D ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autonomic nervous system; Cardiac function; Defense reaction; Emotion; Fight or flight response; Lateral hypothalamic area; Paraventricular hypothalamic nucleus; Periaqueductal gray matter; Precommissural nucleus; Pseudorabies virus; Raphe magnus nucleus

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MICROPHOTOGRAPHY; NEUROPHYSIOLOGY; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PREMOTOR CORTEX; PRIORITY JOURNAL; RAT; SURVIVAL TIME; SYMPATHETIC TONE; THALAMUS VENTRAL NUCLEUS; TISSUE DISTRIBUTION;

ANIMALS; EMOTIONS; FEMALE; GANGLIA, SYMPATHETIC; HEART; HERPESVIRUS 1, SUID; HYPOTHALAMIC AREA, LATERAL; MALE; MOTOR NEURONS; NEURAL PATHWAYS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PERIAQUEDUCTAL GRAY; PHYTOHEMAGGLUTININS; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032507750     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00029-8     Document Type: Article

References (53)

1. Antal M., Sholomenko G.N., Moschovaskis A.K., Storm-Mathisen J., Heizman C.W., Hunziker W. The termination pattern and postsynaptic targets of rubrospinal fibers in the rat spinal cord: a light and electron microscopic study. J. Comp. Neurol. 325:1992;22-37.
2. Bacon S.J., Zagon A., Smith A.D. Electron microscopic evidence of a monosynaptic pathway between cells in the caudal raphe nuclei and sympathetic preganglionic neurons in the rat spinal cord. Exp. Brain Res. 79:1990;589-602.
3. Bandler R., Shipley M.T. Columnar organization in the midbrain periaqueductal gray: modules for emotional expression? Trends Neurosci. 17:1994;379-389.
4. Basbaum A.I., Clanton C.H., Fields H.L. Three bulbospinal pathways from the rostral medulla of the cat: an autoradiographic study of pain modulating systems. J. Comp. Neurol. 17:1978;209-224.
5. Behbehani M.M. Functional characteristics of the midbrain periaqueductal gray. Prog. Neurobiol. 46:1995;575-605.
6. Cabot J.B., Alessi V., Carroll J., Ligorio M. Spinal cord lamina V and lamina VII interneuronal projections to sympathetic preganglionic neurons. J. Comp. Neurol. 347:1994;515-530.
7. Card J.P., Rinaman L., Lynn R.B., Lee B.H., Meade R.P., Miselis R.R., Enquist L.W. Pseudorabies virus infection of the rat central nervous system: ultrastructural characterization of viral replication, transport, and pathogenesis. J. Neurosci. 13:1993;2515-2539.
8. Cameron A.A., Khan I.A., Westlund K.N., Willis W.D. The efferent projections of the periaqueductal gray in the rat: a Phaseolus vulgaris leuco-agglutinin study: II. Descending projections. J. Comp. Neurol. 351:1995;585-601.
9. Carrive P., Bandler R. Control of extracranial and hindlimb blood flow by the midbrain periaqueductal grey of the cat. Exp. Brain Res. 84:1991;599-606.
10. Carrive P., Bandler R. Viscerotopic organization of neurons subserving hypotensive reactions within the midbrain periaqueductal grey: a correlative functional and anatomical study. Brain Res. 541:1991;206-215.
11. Carrive P., Bandler R., Dampney R.A.L. Anatomical evidence that hypertension associated with the defence reaction in the cat is mediated by a direct projection from a restricted portion of the midbrain periaqueductal grey to the subretrofacial nucleus of the medulla. Brain Res. 460:1988;339-345.
12. Chen S., Aston-Jones G. Anatomical evidence for inputs to ventrolateral medullary catecholaminergic neurons from the midbrain periaqueductal gray of the rat. Neurosci. Lett. 195:1995;140-144.
13. Clark F.M., Proudfit H.K. Projections of neurons in the ventromedial medulla to pontine catecholamine cell groups involved in the modulation of nociception. Brain Res. 540:1991;105-115.
14. Craig A.D. Spinal distribution of ascending lamina I axons anterogradely labeled with Phaseolus vulgaris leuco-agglutinin (PHA-L) in the cat. J. Comp. Neurol. 313:1991;377-393.
15. Dampney R.A.L. Functional organization of central pathways regulating the cardiovascular system. Physiol. Rev. 74:1994;323-364.
16. Ennis M., Xu S.J., Rizvi T.A. Discrete subregions of the rat midbrain peraqueductal gray project to nucleus ambiguus and the periambigual region. Neuroscience. 80:1997;829-845.
17. Farkas E., Jansen A.S.P., Loewy A.D. Periaqueductal gray matter projection to vagal preganglionic neurons and the nucleus tractus solitarius. Brain Res. 764:1997;257-261.
18. Fields H.L., Heinricher M.M., Mason P. Neurotransmitters in nociceptive modulatory circuits. Ann. Rev. Neurosci. 14:1991;219-245.
19. Gerfen C.R., Sawchenko P.E. An anterograde neuroanatomical tracing method that shows the detailed morphology of neurons, their axons and terminals: immunohistochemical localization of an axonally transported plant lectin, Phaseolus vulgaris leuco-agglutinin (PHA-L). Brain Res. 290:1984;219-238.
20. Haxhiu M.A., Jansen A.S.P., Cherniack N.S., Loewy A.D. CNS innervation of airway-related parasympathetic preganglionic neurons: a transneuronal labeling study using pseudorabies virus. Brain Res. 618:1993;115-134.
21. Henderson L.A., Keay K.A., Bandler R. The ventrolateral periaqueductal gray projects to the caudal brainstem depressor regions: a functional-anatomical and physiological study. Neuroscience. 82:1998;201-221.
22. Hilton S.M., Redfern W.S. A search for brain stem cell groups integrating the defence reaction in the rat. J. Physiol. (London). 378:1986;213-228.
23. Hunsperger R.W. Affektreaktionen auf electrische Reizung im Hirnstamm der Katze. Helv. Physiol. Pharmacol. Acta (Basel). 14:1956;70-92.
24. Inui K., Murase S., Nosaka S. Facilitation of the arterial baroreflex by the ventrolateral part of the midbrain periaqueductal grey matter in rats. J. Physiol. (London). 477:1994;89-101.
25. Jansen A.S.P., Farkas E., Sams J.M., Loewy A.D. Local connections between the columns of the periaqueductal gray matter: a case for intrinsic modulation. Brain Res. 784:1998;329-336.
26. Jansen A.S.P., Loewy A.D. Neurons lying in the white matter of the upper cervical spinal cord project to the intermediolateral cell column. Neuroscience. 77:1997;889-898.
27. Jansen A.S.P., Nguyen X.V., Karpitskiy V., Mettenleiter T.C., Loewy A.D. Central command neurons of the sympathetic nervous system: basis of the fight-or-flight response. Science. 270:1995;644-646.
28. Jansen A.S.P., Wessendorf M.W., Loewy A.D. Transneuronal labeling of CNS neuropeptide and monoamine neurons after pseudorabies virus injections into the stellate ganglion. Brain Res. 683:1995;1-24.
29. Krieger J.E., Graeff F.G. Defensive behavior and hypertension induced by glutamate in the midbrain central gray of the rat. Braz. J. Med. Biol. Res. 18:1985;61-67.
30. Kwiat G.C., Basbaum A.I. The origin of brainstem noradrenergic and serotonergic projections to the spinal cord dorsal horn in the rat. Somatosen. Motor Res. 9:1992;157-173.
31. LeDoux J.E., Iwata J., Cicchetti P., Reis D.J. Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear. J. Neurosci. 8:1988;2517-2529.
32. Leung C.G., Mason P. Spectral analysis of arterial blood pressure and raphe magnus neuronal activity in anesthetized rats. Am. J. Physiol. 271:1996;R483-R489.
33. Loewy A.D., Franklin M.F., Haxhiu M.A. CNS monoamine cell groups projecting to pancreatic vagal motor neurons: a transneuronal labeling study using pseudorabies virus. Brain Res. 620:1994;323-330.
34. A.D. Loewy, Pseudorabies virus: a transneuronal tracer for neuroanatomical studies, in: M.G. Kaplitt, A.D. Loewy (Eds.), Viral Vectors, Academic Press, San Diego, CA, 1995, pp. 349-366.
35. McDougall A., Dampney R., Bandler R. Cardiovascular components of the defence reaction evoked by excitation of neuronal cell bodies in the midbrain periaqueductal gray of the cat. Neurosci. Lett. 60:1985;69-75.
36. Minson J.B., Chalmers J.P., Caon A.C., Renaud B. Separate areas of rat medulla oblongata with populations of serotonin- and adrenaline-containing neurons alter blood pressure after L-glutamate stimulation. J. Auton. Nerv. Syst. 19:1987;39-50.
37. Mouton L.J., Holstege G. The periaqueductal gray in the cat projects to lamina VIII and the medial part of lamina VII throughout the length of the spinal cord. Exp. Brain Res. 101:1994;253-264.
38. Nicholas A.P., Hancock M.B. Evidence for projections from the rostral medullary raphe onto medullary catecholamine neurons in the rat. Neurosci. Lett. 108:1990;22-28.
39. Pardini B.J., Lund D.D., Schmid P.G. Organization of the sympathetic postganglionic innervation of the rat heart. J. Auton. Nerv. Syst. 28:1989;193-202.
40. Pardini B.J., Lund D.D., Schmid P.G. Innervation patterns of the middle cervical-stellate ganglion complex in the rat. Neurosci. Lett. 117:1990;300-306.
41. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, San Diego, CA, 1997.
42. Pickering A.E., Spanswick D., Logan S.D. 5-Hydoxytryptamine evokes depolarizations and membrane potential oscillations in rat sympathetic preganglionic neurons. J. Physiol. (London). 408:1994;109-121.
43. Reis D.J., Ruggiero D.A., Morrison S.F. The C1 area of the rostral ventrolateral medulla oblongata. A critical brainstem region for control of resting and reflex integration of arterial blood pressure. Am. J. Hypertens. 2:1989;363S-374S.
44. Snowball R.K., Dampney R.A.L., Lumb B.M. Responses of neurones in the medullary raphe nuclei to inputs from visceral nociceptors and the ventrolateral periaqueductal grey in the rat. Exp. Physiol. 82:1997;485-500.
45. Strack A.M., Sawyer W.B., Platt K.B., Loewy A.D. CNS cell groups regulating the sympathetic outflow to adrenal gland as revealed by transneuronal cell body labeling with pseudorabies virus. Brain Res. 491:1989;274-296.
46. L.W. Swanson, Brain Maps, Elsevier, Amsterdam, 1992.
47. Thurston C.L., Randich A. Responses of on and off cells in the rostral ventral medulla to stimulation of vagal afferents and changes in mean arterial blood pressure in intact and cardiopulmonary deafferented rats. Pain. 62:1995;19-38.
48. Tucker D.C., Saper C.B., Ruggiero D.A., Reis D.J. Organization of central adrenergic pathways: I. Relationships of ventrolateral medullary projections to the hypothalamus and spinal cord. J. Comp. Neurol. 259:1987;591-603.
49. G. Ugolini, Transneuronal tracing with alpha-herpesviruses: a review of the methodology, in: M.G. Kaplitt, A.D. Loewy (Eds.), Viral Vectors, Academic Press, San Diego, CA, 1995, pp. 293-319.
50. Van Bockstaele E.J., Akaoka H., Aston-Jones G. Brainstem afferents to the rostral (juxtafacial) nucleus paragigantocellularis: integration of exteroceptive and interoceptive sensory inputs in the ventral tegmentum. Brain Res. 603:1993;1-18.
51. Van Bockstaele E.J., Aston-Jones G., Pieribone V.A., Ennis M., Shipley M.T. Subregions of the periaqueductal gray topographically innervate the rostral ventral medulla in the rat. J. Comp. Neurol. 309:1991;305-327.
52. Van Bockstaele E.J., Pieribone V.A., Aston-Jones G. Diverse afferents converge on the nucleus paragigantocellularis in the rat ventrolateral medulla: retrograde and anterograde tracing studies. J. Comp. Neurol. 290:1989;561-584.
53. Wilson A., Kapp B.A. Effect of lesions of the ventrolateral periaqueductal gray on the Pavlovian conditioned heart rate response in the rabbit. Behav. Neurol. Biol. 62:1994;73-76.