Fitting the two-stage model of carcinogenesis to nested case-control data on the Colorado Plateau uranium miners: Dependence on data assumptions

Radiation and Environmental Biophysics

Volumn 42, Issue 4, 2004, Pages 257-263

  Haylock, Richard G E ^a   Muirhead, Colin R ^a  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

RADON;

ARTICLE; CANCER SUSCEPTIBILITY; CASE CONTROL STUDY; CELL DIFFERENTIATION; CELL GROWTH; CELL TRANSFORMATION; CIGARETTE SMOKING; COHORT ANALYSIS; CONTROLLED STUDY; HUMAN; LUNG CARCINOMA; MAJOR CLINICAL STUDY; MINER; MODEL; OCCUPATIONAL HAZARD; RADIATION EXPOSURE; RISK ASSESSMENT; VULNERABLE POPULATION;

CASE-CONTROL STUDIES; COCARCINOGENESIS; COHORT STUDIES; COLORADO; HUMANS; LUNG NEOPLASMS; MALE; MINING; MODELS, BIOLOGICAL; NEOPLASMS, RADIATION-INDUCED; OCCUPATIONAL EXPOSURE; RADON; SMOKING; URANIUM;

EID: 1342266242     PISSN: 0301634X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00411-003-0213-8     Document Type: Article

References (16)

1. BEIR (1999) VI Report. Health effects of exposure to indoor radon (1999) Advisory Committee on the Biological Effects of Ionizing Radiations. National Acadamy Press, ISBN 0-309-056454-4
2. Hornung RW, Meinhardt T (1987) Qualitative risk assessment of lung cancer in US uranium miners. Health Phys 32:417-420
3. Hornung RW, Deddens JA, Roscoe RJ (1998) Modifiers of lung cancer risk in uranium miners from the Colorado Plateau. Health Phys 74:12-21
4. Moolgavkar SH, Luebeck EG (1990) Two-event model for carcinogenesis: biological, mathematical, and statistical considerations. Risk Anal 10:323-341
5. Moolgavkar SH, Luebeck EG, Krewski D, Zielinski JM (1993) Radon, cigarette smoke, and lung cancer: a re-analysis of the Colorado Plateau uranium miners' data. Epidemiology 4:204-217
6. Luebeck EG, Heidenreich WF, Hazelton WD, Paretzke HG, Moolgavkar SH (1999) Biologically based analysis of the data for the Colorado uranium miners cohort: Age, dose and dose-rate effects. Radiat Res 152:339-351
7. Berry G (1983) The analysis of mortality by the subject-years method. Biometrics 39:173-184
8. Liddell FDK, McDonald JC, Thomas DC (1977) Methods of cohort analysis: appraisal by application to asbestos mining (with discussion). J R Statist Soc A 140:469-491
9. Mantel N (1973) Synthetic retrospective studies and related topics. Biometrics 29:479-486
10. Langholz B, Thomas D, Xiang A, Stram D (1999) Latency analysis in epidemiological studies of occupational exposures: application to the Colorado plateau uranium miners cohort. Am J Ind Med 35:246-256
11. Leenhouts HP (1999) Radon-induced lung cancer in smokers and non-smokers: risk implications using a two-mutation carcinogenesis model. Radiat Environ Biophys 38:57-71
12. Stram DO, Langholz B, Huberman M, Thomas D (1999) Correcting for exposure measurement error in a reanalysis of lung cancer mortality for the Colorado plateau uranium miners cohort. Health Phys 77:265-275
13. Little MP, Haylock RGE, Muirhead CR (2002) Modeling lung tumour risk in radon-exposed uranium miners using generalisations of the two-mutation model of Moolgavkar, Venzon and Knudson. Int J Radiat Biol 78:49-68
14. Little MP (1995) Are two mutations sufficient to cause cancer? Some generalisations of the two-mutation model of carcinogenesis of Moolgavkar, Venson and Knudson, and of the multistage model of Armitage and Doll. Biometrics 51:1278-1291
15. Nag Fortran Numerical Library Mark 19 for OpenVMS (1999) NAG Ltd, Oxford, UK
16. Moolgavkar SH, Knudson AG (1981) Mutation and cancer: a model for human carcinogenesis. J Natl Cancer Inst 66:1037-105