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1
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0037032812
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Molecular mechanisms of axon guidance
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Dickson B.J. Molecular mechanisms of axon guidance. Science. 298:2002;1959-1964.
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Science
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Dickson, B.J.1
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2
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0029959555
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The molecular biology of axon guidance
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Tessier-Lavigne M., Goodman C.S. The molecular biology of axon guidance. Science. 274:1996;1123-1133.
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Science
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Tessier-Lavigne, M.1
Goodman, C.S.2
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6
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0031007904
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Lamina-specific connectivity in the brain: Regulation by N-cadherin, neurotrophins, and glycoconjugates
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Inoue A., Sanes J.R. Lamina-specific connectivity in the brain: regulation by N-cadherin, neurotrophins, and glycoconjugates. Science. 276:1997;1428-1431.
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Science
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Inoue, A.1
Sanes, J.R.2
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7
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0034993397
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N-cadherin regulates target specificity in the Drosophila visual system
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Lee C.H., Herman T., Clandinin T.R., Lee R., Zipursky S.L. N-cadherin regulates target specificity in the Drosophila visual system. Neuron. 30:2001;437-450.
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(2001)
Neuron
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Lee, C.H.1
Herman, T.2
Clandinin, T.R.3
Lee, R.4
Zipursky, S.L.5
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8
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0035950259
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Drosophila LAR regulates R1-R6 and R7 target specificity in the visual system
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Clandinin T.R., Lee C.H., Herman T., Lee R.C., Yang A.Y., Ovasapyan S., Zipursky S.L. Drosophila LAR regulates R1-R6 and R7 target specificity in the visual system. Neuron. 32:2001;237-248.
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(2001)
Neuron
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Clandinin, T.R.1
Lee, C.H.2
Herman, T.3
Lee, R.C.4
Yang, A.Y.5
Ovasapyan, S.6
Zipursky, S.L.7
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9
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0034671891
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Functional requirement for class I MHC in CNS development and plasticity
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Huh G.S., Boulanger L.M., Du H., Riquelme P.A., Brotz T.M., Shatz C.J. Functional requirement for class I MHC in CNS development and plasticity. Science. 290:2000;2155-2159.
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Science
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Huh, G.S.1
Boulanger, L.M.2
Du, H.3
Riquelme, P.A.4
Brotz, T.M.5
Shatz, C.J.6
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10
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0032478533
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Odorant receptors govern the formation of a precise topographic map
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Wang F., Nemes A., Mendelsohn M., Axel R. Odorant receptors govern the formation of a precise topographic map. Cell. 93:1998;47-60.
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Cell
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Wang, F.1
Nemes, A.2
Mendelsohn, M.3
Axel, R.4
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11
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0037031592
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Sidekicks synaptic adhesion molecules that promote lamina-specific connectivity in the retina
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The authors of this paper identified Sidekick (Sdk)-1 and -2, which mediate homophilic adhesion in vitro and direct laminar targeting of neurites in vivo. Sdk-1 and -2 are expressed by nonoverlapping subsets of retinal neurons; each sdk is expressed by presynaptic (amacrine and bipolar) and postsynaptic (ganglion) cells that project to a common inner plexiform (synaptic) sublamina. Sdk proteins are concentrated at synaptic sites implicating that Sdks might be determinants of lamina-specific synaptic connections.
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Yamagata M., Weiner J., Sanes J. Sidekicks synaptic adhesion molecules that promote lamina-specific connectivity in the retina. Cell. 110:2002;649-660 The authors of this paper identified Sidekick (Sdk)-1 and -2, which mediate homophilic adhesion in vitro and direct laminar targeting of neurites in vivo. Sdk-1 and -2 are expressed by nonoverlapping subsets of retinal neurons; each sdk is expressed by presynaptic (amacrine and bipolar) and postsynaptic (ganglion) cells that project to a common inner plexiform (synaptic) sublamina. Sdk proteins are concentrated at synaptic sites implicating that Sdks might be determinants of lamina-specific synaptic connections.
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(2002)
Cell
, vol.110
, pp. 649-660
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Yamagata, M.1
Weiner, J.2
Sanes, J.3
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12
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0034625260
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Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity
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Schmucker D., Clemens J.C., Shu H., Worby C.A., Xiao J., Muda M., Dixon J.E., Zipursky S.L. Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell. 101:2000;671-684.
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(2000)
Cell
, vol.101
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Schmucker, D.1
Clemens, J.C.2
Shu, H.3
Worby, C.A.4
Xiao, J.5
Muda, M.6
Dixon, J.E.7
Zipursky, S.L.8
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13
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0037461755
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Axonal targeting of olfactory receptor neurons in Drosophila is controlled by DsCam
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In this study the authors show that DsCAM is required for specific ORN classes to synapse in the correct glomeruli. DsCAM mutant ORNs frequently terminate in ectopic sites. The morphology of DsCAM mutant axon terminals was abnormal even in cognate targets. DsCAM is expressed in the ORNs and the target PNs during synapse formation. Multiple splicing forms of DsCAM RNA were detected in developing retina.
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Hummel T., Vasconcelos M.L., Clemens J.C., Fishilevich Y., Vosshall L.B., Zipursky S.L. Axonal targeting of olfactory receptor neurons in Drosophila is controlled by DsCam. Neuron. 37:2003;221-231 In this study the authors show that DsCAM is required for specific ORN classes to synapse in the correct glomeruli. DsCAM mutant ORNs frequently terminate in ectopic sites. The morphology of DsCAM mutant axon terminals was abnormal even in cognate targets. DsCAM is expressed in the ORNs and the target PNs during synapse formation. Multiple splicing forms of DsCAM RNA were detected in developing retina.
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(2003)
Neuron
, vol.37
, pp. 221-231
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Hummel, T.1
Vasconcelos, M.L.2
Clemens, J.C.3
Fishilevich, Y.4
Vosshall, L.B.5
Zipursky, S.L.6
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14
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0038697972
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The protocadherin Flamingo is required for axon target selection in the Drosophila visual system
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The authors show that the protocadherin Flamingo (Fmi) is required for R cells to choose their appropriate postsynaptic targets. Fmi protein is dynamically expressed in R1-R6 growth cones during target selection. Loss of Fmi function causes R cells frequently to select spatially inappropriate postsynaptic targets in the lamina. This suggests that Fmi-mediated interactions among R-cell growth cones within the target field regulate target selection.
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Lee R.C., Clandinin T.R., Lee C.H., Chen P.L., Meinertzhagen I.A., Zipursky S.L. The protocadherin Flamingo is required for axon target selection in the Drosophila visual system. Nat. Neurosci. 6:2003;557-563 The authors show that the protocadherin Flamingo (Fmi) is required for R cells to choose their appropriate postsynaptic targets. Fmi protein is dynamically expressed in R1-R6 growth cones during target selection. Loss of Fmi function causes R cells frequently to select spatially inappropriate postsynaptic targets in the lamina. This suggests that Fmi-mediated interactions among R-cell growth cones within the target field regulate target selection.
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(2003)
Nat. Neurosci.
, vol.6
, pp. 557-563
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Lee, R.C.1
Clandinin, T.R.2
Lee, C.H.3
Chen, P.L.4
Meinertzhagen, I.A.5
Zipursky, S.L.6
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15
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0037423919
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The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C. elegans
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The authors study the localization of a set of en passant synapses in C. elegans and discover that signals derived from guidepost cells are essential for patterning synaptic connections and for localizing specific synapses. They also identify an IgSF protein, SYG-1, that could act as the receptor of the guidepost signal. SYG-1 localizes to synapses at early stages of synapse formation. Loss-of-function syg-1 mutants display a synaptic phenotype that resembles that of mutants lacking guidepost cells.
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Shen K., Bargmann C.I. The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C. elegans. Cell. 112:2003;619-630 The authors study the localization of a set of en passant synapses in C. elegans and discover that signals derived from guidepost cells are essential for patterning synaptic connections and for localizing specific synapses. They also identify an IgSF protein, SYG-1, that could act as the receptor of the guidepost signal. SYG-1 localizes to synapses at early stages of synapse formation. Loss-of-function syg-1 mutants display a synaptic phenotype that resembles that of mutants lacking guidepost cells.
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(2003)
Cell
, vol.112
, pp. 619-630
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Shen, K.1
Bargmann, C.I.2
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16
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85030879356
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Positive and negative signals for synaptic specificity are generated by synaptic guidepost protein SYG-2 and its receptor, SYG-1
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In press.
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Shen K, Fetter RD, Bargmann CI: Positive and negative signals for synaptic specificity are generated by synaptic guidepost protein SYG-2 and its receptor, SYG-1. Cell 2004, In press.
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(2004)
Cell
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Shen, K.1
Fetter, R.D.2
Bargmann, C.I.3
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17
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0033044540
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Formation of lamina-specific synaptic connections
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Sanes J.R., Yamagata M. Formation of lamina-specific synaptic connections. Curr. Opin. Neurobiol. 9:1999;79-87.
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(1999)
Curr. Opin. Neurobiol.
, vol.9
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Sanes, J.R.1
Yamagata, M.2
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19
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0034697964
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An olfactory sensory map in the fly brain
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Vosshall L.B., Wong A.M., Axel R. An olfactory sensory map in the fly brain. Cell. 102:2000;147-159.
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(2000)
Cell
, vol.102
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Vosshall, L.B.1
Wong, A.M.2
Axel, R.3
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20
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0037194889
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Making connections in the fly visual system
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Clandinin T.R., Zipursky S.L. Making connections in the fly visual system. Neuron. 35:2002;827-841.
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(2002)
Neuron
, vol.35
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Clandinin, T.R.1
Zipursky, S.L.2
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21
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0033636065
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Afferent growth cone interactions control synaptic specificity in the Drosophila visual system
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Clandinin T.R., Zipursky S.L. Afferent growth cone interactions control synaptic specificity in the Drosophila visual system. Neuron. 28:2000;427-436.
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(2000)
Neuron
, vol.28
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Clandinin, T.R.1
Zipursky, S.L.2
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22
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0000350127
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The development of the optic lobe
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Edited by Bate M, Martinez-Arias A. Cold Spring Harbor, New York: Cold Spring Harbor Press
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Meinertzhagen IA, Hanson TE: The development of the optic lobe. In The Development of Drosophila melanogaster. Edited by Bate M, Martinez-Arias A. Cold Spring Harbor, New York: Cold Spring Harbor Press; 1993.
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(1993)
The Development of Drosophila Melanogaster
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Meinertzhagen, I.A.1
Hanson, T.E.2
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23
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0033520466
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Flamingo, a seven-pass transmembrane Cadherin, regulates planar cell polarity under the control of Frizzled
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Usui T., Shima Y., Shimada Y., Hirano S., Burgess R.W., Schwarz T.L., Takeichi M., Uemura T. Flamingo, a seven-pass transmembrane Cadherin, regulates planar cell polarity under the control of Frizzled. Cell. 98:1999;585-595.
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(1999)
Cell
, vol.98
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Usui, T.1
Shima, Y.2
Shimada, Y.3
Hirano, S.4
Burgess, R.W.5
Schwarz, T.L.6
Takeichi, M.7
Uemura, T.8
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24
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0033402725
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The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family
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Chae J., Kim M.J., Goo J.H., Collier S., Gubb D., Charlton J., Adler P.N., Park W.J. The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family. Development. 126:1999;5421-5429.
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(1999)
Development
, vol.126
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Chae, J.1
Kim, M.J.2
Goo, J.H.3
Collier, S.4
Gubb, D.5
Charlton, J.6
Adler, P.N.7
Park, W.J.8
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25
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0033636246
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Control of dendritic field formation in Drosophila: The roles of Flamingo and competition between homologous neurons
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Gao F.B., Kohwi M., Brenman J.E., Jan L.Y., Jan Y.N. Control of dendritic field formation in Drosophila: the roles of Flamingo and competition between homologous neurons. Neuron. 28:2000;91-101.
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Neuron
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Gao, F.B.1
Kohwi, M.2
Brenman, J.E.3
Jan, L.Y.4
Jan, Y.N.5
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26
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0034697954
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Drosophila dumbfounded: A myoblast attractant essential for fusion
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Ruiz-Gomez M., Coutts N., Price A., Taylor M.V., Bate M. Drosophila dumbfounded: a myoblast attractant essential for fusion. Cell. 102:2000;189-198.
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Cell
, vol.102
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Ruiz-Gomez, M.1
Coutts, N.2
Price, A.3
Taylor, M.V.4
Bate, M.5
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27
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0035164748
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Rst and its paralogue Kirre act redundantly during embryonic muscle development in Drosophila
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Strunkelnberg M., Bonengel B., Moda L.M., Hertenstein A., de Couet H.G., Ramos R.G., Fischbach K.F. Rst and its paralogue Kirre act redundantly during embryonic muscle development in Drosophila. Development. 128:2001;4229-4239.
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(2001)
Development
, vol.128
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Strunkelnberg, M.1
Bonengel, B.2
Moda, L.M.3
Hertenstein, A.4
De Couet, H.G.5
Ramos, R.G.6
Fischbach, K.F.7
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28
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0029166015
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Restricted expression of the IrreC-Rst protein is required for normal axonal projections of columnar visual neurons
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Schneider T., Reiter C., Eule E., Bader B., Lichte B., Nie Z., Schimansky T., Ramos R.G., Fischbach K.F. Restricted expression of the IrreC-Rst protein is required for normal axonal projections of columnar visual neurons. Neuron. 15:1995;259-271.
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Neuron
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Schneider, T.1
Reiter, C.2
Eule, E.3
Bader, B.4
Lichte, B.5
Nie, Z.6
Schimansky, T.7
Ramos, R.G.8
Fischbach, K.F.9
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29
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0034756046
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Unraveling the molecular make-up of the glomerular podocyte slit diaphragm
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Khoshnoodi J., Tryggvason K. Unraveling the molecular make-up of the glomerular podocyte slit diaphragm. Exp. Nephrol. 9:2001;355-359.
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Exp. Nephrol.
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Khoshnoodi, J.1
Tryggvason, K.2
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30
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0034799894
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The lin-11 LIM homeobox gene specifies olfactory and chemosensory neuron fates in C. elegans
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Sarafi-Reinach T.R., Melkman T., Hobert O., Sengupta P. The lin-11 LIM homeobox gene specifies olfactory and chemosensory neuron fates in C. elegans. Development. 128:2001;3269-3281.
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(2001)
Development
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Sarafi-Reinach, T.R.1
Melkman, T.2
Hobert, O.3
Sengupta, P.4
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31
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0032520848
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Control of neural development and function in a thermoregulatory network by the LIM homeobox gene lin-11
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Hobert O., D'Alberti T., Liu Y., Ruvkun G. Control of neural development and function in a thermoregulatory network by the LIM homeobox gene lin-11. J. Neurosci. 18:1998;2084-2096.
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J. Neurosci.
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Hobert, O.1
D'Alberti, T.2
Liu, Y.3
Ruvkun, G.4
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