Surviving severe acute respiratory distress syndrome: Utility of open-lung biopsy and large doses of dexamethasone

Annals of Thoracic Surgery

Volumn 79, Issue 2, 2005, Pages 713-715

  Deshpande, Kedar S ^a   Appel, David W ^b   Camacho, Margarita T ^c   Tanaka, Kathryn E ^c   Kvetan, Vladimir ^d  

^a Divisions Critical Care Pulmon Med   (United States)

^b Montefiore Med Ctr Albert E ^*

^c MONTEFIORE MEDICAL CENTER   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE; OXYGEN;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; BREATHING MECHANICS; CASE REPORT; DISEASE SEVERITY; DRUG MEGADOSE; DYING; EXPIRED AIR; EXTUBATION; FEMALE; HUMAN; INSPIRATORY CAPACITY; OPEN LUNG BIOPSY; OXYGENATION; PRESSURE; PRIORITY JOURNAL; SALVAGE THERAPY; TREATMENT OUTCOME;

ADULT; BIOPSY; DEXAMETHASONE; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLUCOCORTICOIDS; HUMANS; LUNG; METHYLPREDNISOLONE; REMISSION INDUCTION; SEVERE ACUTE RESPIRATORY SYNDROME;

EID: 13244299229     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2003.07.020     Document Type: Article

References (8)

1. Luce J. Corticosteroids in ARDS an evidence based review. Crit Care Clin. 18:(1):2002;79-89
2. Meduri G.U., Chinn A.J., Leeper K.V., et al. Corticosteroid rescue treatment of progressive fibroproliferation in late ARDS. Chest. 105:1994;1516-1527
3. Meduri GU, Tolley EA, Chrousos GP, et al. Prolonged methylprednisolone treatment suppresses systemic inflammation in patients with unresolving acute respiratory distress syndrome. Evidence for inadequate endogenous glucocorticoid secretion and inflammation-induced immune cell resistance to glucocorticoids. Am J Respir Crit Care Med 2002(165):983-91
4. Meduri G.U., Belenchia J.M., Estes R.J., et al. Fibroproliferative phase of ARDS clinical findings and effect of corticosteroids. Chest. 100:(4):1991;943-952
5. Williams T.J., Yarwood H. Effects of glucocorticosteroids on microvascular permeability. Am Rev Respir Dis. 141:1990;S39-43
6. Bracken M.B., Shepard M.J., Collins W.F., et al. The randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. N Engl J Med. 322:(20):1990;1405-1411
7. Luce J.M., Montgomery A.B., Marks J.D., et al. Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock. Am Rev Respir Dis. 138:1988;62-68
8. Grunze M.F., Parkinson D., Sulavik S.B., et al. Effect of corticosteroids on lung volume-pressure curves in bleomycin-induced lung injury in the rat. Exp Lung Res. 14:(2):1988;183-195