Studies on in vivo gene transfer in pituitary tumors using herpes-derived and adenoviral vectors

Brain Research Bulletin

Volumn 65, Issue 1, 2005, Pages 17-22

  Carri, Néstor G ^a   Sosa, Yolanda E ^b   Brown, Oscar A ^b   Albariño, César ^c   Romanowski, Víctor ^c,d   Goya, Rodolfo G ^b  

^a Instituto Multidisciplinario de Biologia Celular   (Argentina)

^b FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

^c FACULTAD DE CIENCIAS EXACTAS   (Argentina)

^d UNIVERSIDAD NACIONAL DE QUILMES   (Argentina)

Author keywords

Gene therapy; Intrapituitary injection; Prolactinomas; Viral vectors; Virus distribution

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; GROWTH HORMONE; HERPESVIRUS VECTOR; PROLACTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DENSITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GROWTH HORMONE BLOOD LEVEL; HYPOPHYSIS TUMOR; NONHUMAN; PLAQUE FORMING CELL; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PROLACTINOMA; RAT; REPORTER GENE; SUICIDE GENE THERAPY; TRANSGENE;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; CELL COUNT; CELL DEATH; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESTRADIOL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, TRANSGENIC, SUICIDE; GENETIC VECTORS; GROWTH HORMONE; HERPESVIRUS 1, HUMAN; INDOLES; PITUITARY GLAND; PITUITARY NEOPLASMS; PROLACTIN; PROLACTINOMA; RATS; RATS, SPRAGUE-DAWLEY; STEREOTAXIC TECHNIQUES; THYMIDINE KINASE;

EID: 13244294186     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2004.10.008     Document Type: Article

References (19)

1. F. Bolognani, C. Albariño, V. Romanowski, N.G. Carri, and R.G. Goya In vitro and in vivo herpetic vector-mediated gene transfer in the pituitary gland: impact on hormone secretion Eur. J. Endocr. 145 2001 497 503
2. M.G. Castro, S. Goverdhana, J. Hu, N. Jovel, X. Yuan, and P.R. Lowenstein Gene therapy for pituitary tumors: from preclinical models to clinical implementation Front. Neuroendocrinol. 24 2003 62 77
3. M.G. Castro, R.G. Goya, Y.E. Sosa, J. Rowe, A.T. Larregina, A.E. Morelli, and P.R. Lowenstein Expression of transgenes in normal and neoplastic anterior pituitary cells using recombinant adenoviruses: long term expression, cell cycle dependency, and effects on hormone secretion Endocrinology 138 1997 2184 2194
4. A.T. Dobson, T.P. Margolis, F. Sedarati, J.G. Stevens, and L.T. Feldman A latent nonpathogenic HSV-1-derived vector stably expresses beta-galactosidase in mouse neurons Neuron 5 1990 353 360
5. R.G. Goya, D.K. Sarkar, O.A. Brown, and C.B. Hereñú Potential of gene therapy for the treatment of pituitary tumors Curr. Gene Ther. 4 2004 79 87
6. R.G. Goya, J. Rowe, Y.E. Sosa, P. Tomasec, P.R. Lowenstein, and M.G. Castro Use of recombinant herpes simplex virus type I vectors for gene transfer into tumour and normal anterior pituitary cells Mol. Cell Endocrinol. 139 1998 199 207
7. Guidelines on Handling and Training of Laboratory Animals. The Biological Council Animal Research and Welfare Panel (Eds.), UFAW, Pert, 1992.
8. P.A. Johnson, A. Miyanohara, F. Levine, T. Cahill, and T. Friedmann Cytotoxicity of a replication-defective mutant of HSV type 1 J. Virol. 66 1992 2952 2965
9. E.J. Lee, L.M. Anderson, B. Thimmapaya, and J.L. Jameson Targeted expression of toxic genes directed by pituitary hormone promoters: a potential strategy for adenovirus-mediated gene therapy of pituitary tumors J. Clin. Endocrinol. Metab. 84 1999 786 794
10. E.J. Lee, F. Martinson, T. Kotlar, B. Thimmapaya, and J.L. Jameson Adenovirus-mediated targeted expression of toxic genes to adrenocorticotropin- producing pituitary tumors using the proopiomelanocortin promoter J. Clin. Endocrinol. Metab. 86 2001 3400 3409
11. E.J. Lee, B. Thimmapaya, and J.L. Jameson Stereotactic injection of adenoviral vectors that target gene expression to specific pituitary1 cell types: implications for gene therapy Neurosurgery 46 2000 1461 1469
12. G. Le Gal La Salle, J.J. Robert, S. Berrard, V. Ridoux, L.D. Stratford-Perricaudet, M. Perricaudet, and J. Mallet An adenovirus vector for gene transfer into neurons and glia in the brain Science 259 1993 988 990
13. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates, San Diego 1986 Academic Press
14. J.R. Smith-Arica, J.C. Williams, D. Stone, J. Smith, P.R. Lowenstein, and M.G. Castro Switching on and off transgene expression within lactotrophic cells in the anterior pituitary gland in vivo Endocrinology 142 2001 2521 2532
15. T.D. Southgate, S. Windeatt, J. Smith-Arica, C.A. Gerdes, M.J. Perone, I. Morris, J.R. Davis, D. Klatzmann, P.R. Lowenstein, and M.G. Castro Transcriptional targeting to anterior pituitary lactotrophic cells using recombinant adenovirus vectors in vitro and in vivo in normal and estrogen/sulpiride-induced hyperplastic anterior pituitaries Endocrinology 141 2000 3493 3505
16. L.D. Stratford-Perricaudet, I. Makeh, M. Perricaudet, and P. Briand Widespread long-term gene transfer to mouse skeletal muscles and heart J. Clin. Invest. 90 1992 626 630
17. P. Tomasec, D. Bain, M.G. Castro, C.M. Preston, and P.R. Lowenstein Herpes simplex virus temperature-sensitive mutant tsK as a vector for neuronal gene transfer P.R. Lowenstein L.W. Enquist Protocols for Gene Transfer in Neuroscience: Towards Gene Therapy of Neurological Disorders 1996 John Wiley & Sons Chichester 169 186
18. P. Tomasec, C.M. Preston, E.A. Linton, I. Ahmed, P.R. Lowenstein, and M.G. Castro Generation of a recombinant herpes simplex virus type 1 expressing the rat corticotropin-releasing hormone precursor: endoproteolytic processing, intracellular targeting and biological activity Neuroendocrinology 70 1999 439 450
19. S. Windeatt, T.D. Southgate, R.A. Dewey, F. Bolognani, M.J. Perone, A.T. Larregina, T.C. Maleniak, I.D. Morris, R.G. Goya, D. Klatzmann, P.R. Lowenstein, and M.G. Castro Adenovirus-mediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas J. Clin. Endocrinol. Metab. 85 2000 1296 1305