Direct coupling of pyrroles with carbonyl compounds: Short enantioselective synthesis of (S)-ketorolac

Angewandte Chemie - International Edition

Volumn 44, Issue 4, 2005, Pages 609-612

  Baran, Phil S ^a   Richter, Jeremy M ^a   Lin, David W ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

C C coupling; Copper; Enantioselectivity; Heterocycles; Total synthesis

Indexed keywords

CARBONYLATION; DRUG PRODUCTS; ESTERS; SYNTHESIS (CHEMICAL);

ANTI-INFLAMMATORY DRUGS; CARBONYL COMPOUNDS; PYRROLES;

AROMATIC HYDROCARBONS;

AMIDE; CARBONYL DERIVATIVE; ESTER; KETONE; KETOROLAC; LACTAM; LACTONE; PYRROLE DERIVATIVE;

ARTICLE; CRYSTALLOGRAPHY; CYCLIZATION; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE;

KETOROLAC; PYRROLES; STEREOISOMERISM;

EID: 13244269968     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200462048     Document Type: Article

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