Immunohistochemical analysis of SOX6 expression in human brain tumors

Brain Tumor Pathology

Volumn 21, Issue 3, 2004, Pages 117-120

  Ueda, Ryo ^a   Yoshida, Kazunari ^a   Kawakami, Yutaka ^a   Kawase, Takeshi ^a   Toda, Masahiro ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Brain tumor; Neural stem progenitor cell; SOX6; Undifferentiated cell

Indexed keywords

ANTIGEN EXPRESSION; ARTICLE; ASTROCYTE; BRAIN CELL; BRAIN TUMOR; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM TUMOR; DIAGNOSTIC VALUE; EMBRYO (ANATOMY); FETUS (ANATOMY); GENE; GENE EXPRESSION REGULATION; GLIA CELL; GLIOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NEURAL STEM CELL; NEUROEPITHELIOMA; OLIGODENDROGLIA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOX6 GENE; TUMOR DIAGNOSIS; TUMOR DIFFERENTIATION; VALIDATION PROCESS;

BRAIN NEOPLASMS; CELL LINEAGE; DNA-BINDING PROTEINS; HIGH MOBILITY GROUP PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; STEM CELLS; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 13244249772     PISSN: 14337398     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02482186     Document Type: Article

References (22)

1. Holland EC (2001) Progenitor cells and glioma formation. Curr Opin Neurol 14:683-688
2. Dai C, Celestino JC, Okada Y, et al (2001) PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev 15:1913-1925
3. Fults D, Pedone C, Dai C, et al (2002) MYC expression promotes the proliferation of neural progenitor cells in culture and in vivo. Neoplasia 4:32-39
4. Holland EC, Celestino J, Dai C, et al (2000) Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat Genet 25:55-57
5. Dahlstrand J, Collins VP, Lendahl U (1992) Expression of the class VI intermediate filament nestin in human central nervous system tumors. Cancer Res 52:5334-5341
6. Tohyama T, Lee VM, Rorke LB, et al (1992) Nestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cells. Lab Invest 66:303-313
7. Ueda R, Iizuka Y, Yoshida K, et al (2004) Identification of a human glioma antigen, SOX6, recognized by patients' sera. Oncogene 23:1420-1427
8. Ueda R, Yoshida K, Kawakami Y, et al (2004) Expression of a transcriptional factor, SOX6, in human gliomas. Brain Tumor Pathol 21:35-38
9. Connor F, Wright E, Denny P, et al (1995) The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse. Nucleic Acids Res 23:3365-3372
10. Hemmati HD, Nakano I, Lazareff JA, et al (2003) Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci U S A 100:15178-15183
11. Ignatova TN, Kukekov VG, Laywell ED, et al (2002) Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia 39:193-206
12. Leung C, Lingbeek M, Shakhova O, et al (2004) Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 428:337-341
13. Toda M, Iizuka Y, Yu W, et al (2001) Expression of the neural RNA-binding protein Musashi1 in human gliomas. Glia 34:1-7
14. Kleihues P, Louis DN, Scheithauer BW, et al (2002) The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 61:215-225
15. Rao G, Pedone CA, Coffin CM, et al (2003) c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice. Neoplasia 5:198-204
16. Laudet V, Stehelin D, Clevers H (1993) Ancestry and diversity of the HMG box superfamily. Nucleic Acids Res 21:2493-2501
17. Prior HM, Walter MA (1996) SOX genes: architects of development. Mol Med 2:405-412
18. Wegner M (1999) From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 27:1409-1420
19. Dyer MA (2004) Mouse models of childhood cancer of the nervous system. J Clin Pathol 57:561-576
20. Mendelsohn G, Maksem JA (1986) Divergent differentiation in neoplasms. Pathologic, biologic, and clinical considerations. Pathol Annu 21(Pt 1):91-119
21. Valdueza JM, Westphal M, Vortmeyer A, et al (1996) Central neurocytoma: clinical, immunohistologic, and biologic findings of a human neuroglial progenitor tumor. Surg Neurol 45:49-56
22. von Deimling A, Kleihues P, Saremaslani P, et al (1991) Histogenesis and differentiation potential of central neurocytomas. Lab Invest 64:585-591