A deletion causing spontaneous fracture identified from a candidate region of mouse chromosome 14

Mammalian Genome

Volumn 16, Issue 1, 2005, Pages 20-31

  Jiao, Yan ^a   Li, Xinmin ^b   Beamer, Wesley G ^c   Yan, Jian ^a   Tong, Yiai ^a   Goldowitz, Daniel ^a   Roe, Bruce ^d   Gu, Weikuan ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c JACKSON LABORATORY   (United States)

^d UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; GULONOLACTONE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE FRAGILITY; CHROMOSOME 14; CONTROLLED STUDY; ENZYME SYNTHESIS; EXAMINATION; EXON; FEMALE; FEMUR FRACTURE; GENE DELETION; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCATION; GENE LOCUS; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENOME; HIGH THROUGHPUT SCREENING; MALE; MOLECULAR CLONING; NONHUMAN; PHENOTYPE;

ANIMALS; CHROMOSOME MAPPING; FEMALE; FEMORAL FRACTURES; FRACTURES, SPONTANEOUS; GENE DELETION; IN SITU HYBRIDIZATION; L-GULONOLACTONE OXIDASE; LIVER; LUNG; MALE; MICE; MYOCARDIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPINE; SUGAR ALCOHOL DEHYDROGENASES;

ANIMALIA;

EID: 13244249687     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-004-2414-0     Document Type: Article

References (27)

1. Beamer WG, Rosen CJ, Bronson RT, Gu W-K, Donahue LR, et al. (2000) Spontaneous fracture (sfx): a mouse genetic model of defective peripubertal bone formation. Bone 27(5), 619-626
2. Brooks MB, Gu W, Barnas JL, Ray J, Ray K (2003) A line 1 insertion in the factor IX gene segregates with mild hemophilia B in dogs. Mamm Genome 14, 788-795
3. Ellender G, Gazelakis T (1996) Growth and bone remodeling in a scorbutic rat model. Aust Dent J 41(2), 97-106
4. Gu W, Acland GM, Langston AA, et al. (1998) Identification of a RAPD marker linked to progressive rod-cone degeneration in dogs. Mamm Genom 9, 740-744
5. Gu W, Brooks M, Catalfamo J, Ray J, Ray K (1999a) Two distinct mutations cause severe hemophilia B in two unrelated canine pedigrees. Thromb Haemost 82, 1270-1275
6. Gu W, Ray K, Pearce-Kelling S, Baldwin VJ, Langston AA, et al. (1999b) Evaluation of apolipoprotein H (APOH) gene as a positional candidate gene for progressive rod-cone degeneration (prcd) disease. Invest Ophthalmol Vis Sci 40, 1229-1237
7. Gu WJ, Li XM, Edderkaoui B, Strong DD, Lau KH, et al. (2002a) Constrution of a BAC contig for a 3 cM biologically significant region of mouse chromosome 1. Genetica 114(1), 1-9
8. Gu W, Li X, Lau KH, Edderkaoui B, Donahae LR, et al. (2002b) Gene expression between a congenic strain that contains a quantitative trait locus of high bone density from CAST/EiJ and its wild-type strain C57BL/ 6 J. Funct Integr Genomics 1(6), 375-386
9. Gu W, Li XM, Roe BA, Lau KH, Edderkaoui B, et al. (2003) Application of genomic resources and gene expression profiles to identify genes that regulate bone density. Curr Genomics 4, 75-102
10. Guerriero C, De Santis D, Nocini PF, Gotte P, Armato U (1995) Tissue culture of adult human osteoblasts isolated from jaw bones. Ital J Anat Embryol 100 Suppl 1, 83-93
11. Hasan L, Vogeli P, Neuenschwander S, Stoll P, Meijerink E, et al. (1999) The L-gulono-gamma-lactone oxidase gene (GULO) which is a candidate for vitamin C deficiency in pigs maps to chromosome 14. Anim Genet 30(4), 309-312
12. Horai R, Saijo S, Tanioka H, Nakae S, Sudo K, et al. (2000) Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin receptor antagonist-deficient. J Exp Med 191(2), 313-320
13. Horio F, Hayashi K, Mishima T, Takemori K, Oshima I, et al. (2001) A newly established strain of spontaneously hypertensive rat with a defect of ascorbic acid biosynthesis. Life Sci 69(16), 1879-1890
14. Kawai T, Nishikimi M, Ozawa T, Yagi K (1992) A missense mutation of L-gulono-gamma-lactone oxidase causes the inability of scurvy-prone osteogenic disorder rats to synthesize L-ascorbic acid. J Biol Chem 267, 21973-21976
15. Kawai K, Ito H, Kubota H, Takemori K, Makino S, et al. (2003) Changes in catecholamine metabolism by ascorbic acid deficiency in spontaneously hypertensive rats unable to synthesize ascorbic acid. Life Sci 72(15), 1717-1732
16. Kipp DE, McElvain M, Kimmel DB, Akhter MP, Robinson RG, et al. (1996) Scurvy results in decreased collagen synthesis and bone density in the guinea pig animal model. Bone 18(3), 281-288
17. Li X, Gu W, Masinde G, Xu S, Mohan D, et al. (2001) Genetic control of the rate of wound healing in mice. Heredity 86, 668-674
18. Li X, Masinde GI, Gu W, Wergedal J, Hamilton-Ulland M, et al. (2002) Chromosomal regions harboring genes for the work to femur failure; in mice. Funct Integr Genomics 1(6), 367-374
19. Maeda N, Hagihara H, Nakata Y, Killer S, Wilder J, et al. (2000) Aortic wall damage in mice unable to synthesize ascorbic acid. Proc Natl Acad Sci USA 97(2), 841-846
20. Nakata Y, Maeda N (2002) Vulnerable atherosclerotic plaque morphology in apolipoprotein E-deficient mice unable to make ascorbic acid. Circulation 105(12), 1485-1490
21. Nishikimi M, Kawai T, Yagi K (1992) Guinea pigs possess a highly mutated gene for L-gulono-gamma-lactone oxidase, the key enzyme for L-ascorbic acid biosynthesis missing in this species. J Biol Chem 267, 21967-21972
22. Sakamoto Y, Takano Y (2002) Morphological influence of ascorbic acid deficiency on endochondral ossification in osteogenic disorder Shionogi rat. Anat Reg 268(2), 93-104
23. Sotiriou S, Gispert S, Cheng J, Wang Y, Chen A, et al. (2002) Ascorbic-acid transporter Slc23al is essential for vitamin C transport into the brain and for perinatal survival. Nat Med 8, 514-517
24. Tong Y, Dumont Y, Shen SH, Quirion R (1997) Comparative developmental profile of the neuropeptide YY1 receptor gene and protein in the rat brain. Mol Brain Res 48, 323-332
25. Tumber A, Meikle MC, Hill PA (2000) Autocrine signals promote osteoblast survival in culture. J Endocrinol 167(3), 383-390
26. Waterston RH, et al. (2002) (Mouse Genome Sequencing Consortium) Initial sequencing and comparative analysis of the mouse genome. Nature 420, 520-562
27. Wegger I, Palludan B (1994) Vitamin C deficiency causes hematological and skeletal abnormalities during fetal development in swine. J Nutr 124(2), 241-248