Replacement of murine by human CD4 and introduction of HLA-DR17 in mice: A triple-transgenic animal model to study human MHC II-CD4 interaction in situ

Journal of Experimental Animal Science

Volumn 39, Issue 4, 1999, Pages 122-135

  Laub, Rüdiger ^a,c   Dorsch, Martina ^b   Wedekind, Dirk ^b   Meyer, Dorothea ^a   Schröder, Sabine ^a   Ermann, Jörg ^a   Lehmann, Jörg ^a   Mähler, Michael ^b   Emmrich, Frank ^a   Hedrich, Hans J ^b  

^a Institute of Clinical Immunology and Transfusion Medicine   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

CD4; MHC class II; Monoclonal antibodies; T cell activation; Transgenic mice

Indexed keywords

CD4 ANTIGEN; EPITOPE; HLA DR ANTIGEN; HLA DR17 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; PRIMER DNA; UNCLASSIFIED DRUG;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BETA CHAIN; BREEDING; FEMALE; FLOW CYTOMETRY; GENE AMPLIFICATION; GENE EXPRESSION; GENOTYPE; HUMAN CELL; INBRED STRAIN; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROGENY; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TRANSGENE; TRANSGENIC ANIMAL;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 13044283049     PISSN: 09398600     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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