Modeling evolutionary landscapes: Mutational stability, topology, and superfunnels in sequence space

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 19, 1999, Pages 10689-10694

  Bornberg Bauer, Erich ^a,c   Chan, Hue Sun ^b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF TORONTO   (Canada)

^c European Media Laboratory   (Germany)

Author keywords

Fitness landscapes; Folding funnels; Lattice protein models; Neutral mutations; Thermodynamic stability

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; EVOLUTION; MATHEMATICAL MODEL; MUTATION; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STABILITY; THERMOSTABILITY;

ALGORITHMS; EVOLUTION, MOLECULAR; MODELS, GENETIC; MODELS, THEORETICAL; MUTATION; PROTEIN CONFORMATION; THERMODYNAMICS;

EID: 13044269058     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.19.10689     Document Type: Article

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