Leydig cell tumour-induced bilateral gynaecomastia in a young man: Endocrine abnormalities

Andrologia

Volumn 37, Issue 1, 2005, Pages 36-39

  Foppiani, L ^a   Bernasconi, D ^a   Del Monte, P ^a   Marugo, A ^a   Toncini, C ^b   Marugo, M ^a  

^a GALLIERA HOSPITAL   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

17 oestradiol; Gynaecomastia; hCG testing; Hypogonadism; Leydig cell tumour

Indexed keywords

CHORIONIC GONADOTROPIN; ESTRADIOL; TESTOSTERONE;

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DISEASE COURSE; ECHOGRAPHY; ENDOCRINE DISEASE; ESTRADIOL BLOOD LEVEL; GYNECOMASTIA; HUMAN; HUMAN TISSUE; HYPOGONADISM; LEYDIG CELL TUMOR; MALE; PHYSICAL EXAMINATION; SEMEN ANALYSIS; TESTIS CARCINOMA; TESTIS SIZE; TESTOSTERONE BLOOD LEVEL; TREATMENT OUTCOME; TUMOR DIAGNOSIS;

ADULT; CHORIONIC GONADOTROPIN; ESTRADIOL; GYNECOMASTIA; HUMANS; LEYDIG CELL TUMOR; MALE; TESTICULAR NEOPLASMS;

EID: 12944333131     PISSN: 03034569     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1439-0272.2004.00648.x     Document Type: Article

References (17)

1. Anderson MS, Brogi E, Biller BM (2001) Occult Leydig cell tumor in a patient with gynecomastia. Endocr Pract 7:267-271.
2. Bercovici JP, Nahoul K, Ducasse M, Tater D, Kerlan V, Scholler R (1985) Leydig cell tumor with gynecomastia: further studies. The recovery after unilateral orchidectomy. J Clin Endocrinol Metab 61:957-962.
3. Braunstein GD (1993) Gynecomastia. N Engl J Med 328:490-495.
4. Braunstein GD (1999) Aromatase and gynecomastia. Endocr Relat Cancer 6:315-324.
5. Cheville JC (1999) Classification and pathology of testicular germ cell and sex cord-stromal tumors. Urol Clin North Am 26:595-609.
6. Duprac C, Boissiere-Veverka G, Lefebvre H, Laquerriere A, Vuillermet P, Landreat A, Ivell R, DeRoux N, Kuhn JM (2003) An oestrogen-producing seminoma responsible for gynecomastia. Horm Metab Res 35:324-329.
7. Gana BM, Windsor PM, Lang G, Macintyre J, Baxby K (1995) Leydig cell tumor. Br J Urol 75:676-678.
8. Glass AR (1994) Gynecomastia. Endocrinol Metab Clin North Am 4:825-837.
9. Ho GT, Gardner H, Mostofi K, De Wolf WC, Loughlin KR, Morgentaler A (1994) The effect of testicular nongerm cell tumors on local spermatogenesis. Fertil Steril 62:162-166.
10. Ismail AAA, Earth JH (2001) Endocrinology of gynaecomastia. Ann Clin Biochem 38:596-607.
11. Kuhn JM, Mahoudeau JA, Billaud L, Joly J, Rieu M, Gancel A, Archambeaud-Mouveroux F, Steg A, Luton JP (1987) Evaluation of diagnostic criteria for Leydig cell tumours in adult men revealed by gynecomastia. Clin Endocrinol (Oxf) 26:407-416.
12. Kuhn JM, Reznik Y, Mahoudeau JA, Courtois H, Lefebvre H, Wolf LM, Luton JP (1989) hCG test in gynaecomastia: further study. Clin Endocrinol (Oxf) 31:581-590.
13. Kuhn JM, Duranteau L, Rieu MA, Lahlou N, Roger M, Luton JP (1994) Evidence of oestradiol-induced changes in gonadotrophin secretion in men with feminizing Leydig cell tumours. Eur J Endocrinol 131:160-166.
14. Lemack GE, Poppas DP, Vaughan ED Jr (1995) Urologic causes of gynecomastia: approach to diagnosis and management. Urology 45:313-319.
15. Mati W, Lam G, Dahl C, Thorup Andersen J, Balslev E (2002) Leydig cell tumour - a rare testicular tumour. Int Urol Nephrol 33:103-105.
16. Saunders PT, Sharpe RM, Williams K, Macpherson S, Urquart H, Irvine DS, Millar MR (2001). Differential expression of estrogen receptor alpha and beta proteins in the testes and male reproductive system of human and non-human primates. Mol Hum Reprod 7:227-236.
17. Zarilli S, Lombardi G, Paesano L, Di Somma C, Colao A, Mirone V, De Rosa M (2000) Hormonal and seminal evaluation of Leydig cell tumour patients before and after orchiectomy. Andrologia 32:147-154.