An attempt of identifying MS-associated loci as a follow-up of a genomic linkage study in the Italian population

Journal of NeuroVirology

Volumn 6, Issue SUPPL. 2, 2000, Pages

  D'Alfonso, Sandra ^a   Nisticò, Lorenza ^b   Bocchio, Daniela ^a   Bomprezzi, Roberto ^c   Marrosu, Maria Giovanna ^d   Murru, Maria Rita ^d   Lai, Marina ^d   Massacesi, Luca ^e   Ballerini, Clara ^e   Repice, Anna ^e   Salvetti, Marco ^c   Montesperelli, Chiara ^c   Ristori, Giovanni ^c   Trojano, Maria ^f   Liguori, Maria ^f   Gambi, Domenico ^g   Quattrone, Aldo ^h   Tosi, Roberto ^b   Momigliano Richiardi, Patricia ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b CNR   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY OF CAGLIARI   (Italy)

^e UNIVERSITY OF FLORENCE   (Italy)

^f UNIVERSITY OF BARI   (Italy)

^g UNIVERSITY OF CHIETI   (Italy)

^h UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

Association study; Candidate regions; Italian families; Microsatellites; Multiple sclerosis

Indexed keywords

MARKER; MICROSATELLITE DNA;

CHROMOSOME 19Q; CONFERENCE PAPER; DNA DETERMINATION; GENE LOCUS; GENETIC LINKAGE; HUMAN; ITALY; MULTIPLE SCLEROSIS; POPULATION GENETICS; PRIORITY JOURNAL;

ALLELES; CHROMOSOMES, HUMAN, PAIR 19; FAMILY HEALTH; FOLLOW-UP STUDIES; HISTOCOMPATIBILITY TESTING; HLA-DR ANTIGENS; HUMANS; ITALY; LINKAGE (GENETICS); MICROSATELLITE REPEATS; MULTIPLE SCLEROSIS;

EID: 12944293174     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (13)

1. Ashworth LK, Batzer MA, Brandriff B, Branscomb E, de Jong P, Garcia E, Games JA, Gordon LA, Lamerdin JE, Lennon G, Mohrenweiser, AA Olsen, Slezak T, Carrano AV. (1995). An integrated metric physical map of human chromosome 19. Nat Genet 11: 422-427.
2. Barcellos LF, Thomson G, Carrington M, Schafer J, Begovich AB, Lin P, Xu XH, Min BQ, Marti D, Klitz W (1997). Chromosome 19 single-locus and multilocus haplotype associations with multiple sclerosis. Evidence of a new susceptibility locus in Caucasian and Chinese patients. JAMA 278: 1256-1261.
3. D'Alfonso S, Nistico' L, Zavattari P, Marrosu M, Murru R, Lai M, Massacesi L, Ballerini C, Gestri D, Salvetti M, Ristori G, Bomprezzi R, Trojano M, Liguori M, Gambi D, Quattrone A, Fruci D, Cucca F, Momigliano Richiardi P, Tosi R (1999). Linkage analysis of Multiple Sclerosis with candidate region markers in Sardinian and Continental Italian families. Eur J Hum Genet 7: 377-385.
4. Dib C, Faure S, Fizames C, Samson D, Drouot N, Vignal A, Millasseau P, Marc S, Hazan J, Seboun E, Lathrop M, Gyapay G, Morissette J, Weissenbach J (1996). A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 380: 152-154.
5. Ebers GC, Kukay K, Bulman DE, Sadovnick AD, Rice G, Anderson A, Armstrong H, Cousin K, Bell RB, Hader W, Paty DW, Hashimoto S, Oger J, Duquette P, Warren S, Gray T, O'Connor P, Nath A, Auty A, Metz L, Francis G, Paulseth JE, Murray TJ, Pryse-Phillips W, Nelson R, Freedman M, Brunet D, Bouchard JP, Hinds D, Risch N. (1996). A full genome screen in multiple sclerosis. Nat Genet 13: 472-476.
6. Haines JL for The Multiple Sclerosis Genetics Group (1996). A complete genomic screen for multiple sclerosis underscores a role for the major histocompatibility complex. Nat Genet 13: 469-471.
7. Kaneda Y, Hayes H, Uchida T, Yoshida MG, Okada Y (1987). Regional assignment of five genes on human chromosome 19. Chromosome 95: 8-12.
8. Marrosu MG, Murru MR, Costa G, Cucca F, Sotgiu S, Rosati G, Muntoni F (1997). Multiple sclerosis in Sardinia is associated and in linkage disequilibrium with HLA-DR3 and DR4 alleles. Am J Hum Genet 61: 454-457.
9. Martin ER, Kaplan NL, Weir BS (1997). Tests for linkage and association in nuclear families. Am J Hum Genet 61: 439-448.
10. Rasko JEJ, Battini J-L, Gottschalk RJ, Mazo I, Miller AD (1999). The RD114/simian type D retrovirus receptor is a neutral amino acid transporter. Proc Natl Acad Sci 96: 2129-2134.
11. Sawcer S, Jones HB, Feakes R et al. (1996). A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat Genet 13: 464-468.
12. Spielman RS, McGinnis RE, Ewens WJ (1993). Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52: 506-516.
13. Thompson EA, Neel JV (1997). Allelic disequilibrium and allele frequency distribution as a function of social and demographic history. Am J Hum Genet 60: 197-204.