High dose of Garcinia cambogia is effective in suppressing fat accumulation in developing male Zucker obese rats, but highly toxic to the testis

Food and Chemical Toxicology

Volumn 43, Issue 3, 2005, Pages 411-419

  Saito, M ^a   Ueno, M ^a   Ogino, S ^a   Kubo, K ^a   Nagata, J ^a   Takeuchi, M ^b  

^a NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^b Sapporo General Pathology Laboratory   (Japan)

Author keywords

( ) hydroxycitric acid; Epididymal fat accumulation; Garcinia cambogia; Testicular toxicity; Testis; Zucker obese rat

Indexed keywords

GARCINIA CAMBOGIA EXTRACT; GARCINIA CAMBOGIA POWDER S; HYDROXYCITRIC ACID; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DIET; DRUG POTENCY; DRUG SAFETY; EPIDIDYMIS; EXAMINATION; FEEDING; GARCINIA CAMBOGIA; HISTOPATHOLOGY; LIPID STORAGE; MALE; NONHUMAN; OBESITY; OBSERVATION; RAT; REPRODUCTIVE TOXICITY; TESTIS ATROPHY;

ADIPOSE TISSUE; ANIMALS; ANTI-OBESITY AGENTS; ATP CITRATE (PRO-S)-LYASE; CITRATES; DOSE-RESPONSE RELATIONSHIP, DRUG; GARCINIA CAMBOGIA; LEPTIN; LIVER; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; PLANT EXTRACTS; RANDOM ALLOCATION; RATS; RATS, ZUCKER; TESTIS; TESTOSTERONE; WEIGHT GAIN;

GARCINIA; GARCINIA CAMBOGIA;

EID: 12844285659     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2004.11.008     Document Type: Article

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