β-thalassaemia carrier detection by ELISA: A simple screening strategy for developing countries

Journal of Clinical Laboratory Analysis

Volumn 19, Issue 1, 2005, Pages 22-25

  Ravindran, M Shyla ^a   Patel, Zareen M ^a   Khatkhatay, M Ikram ^a   Dandekar, S P ^b  

^a Genetic Research Centre India   (India)

^b KEM HOSPITAL   (India)

Author keywords

Enzyme linked immunosorbent assay; Hemoglobin A2; India, control of thalassaemia; Simple method

Indexed keywords

HEMOGLOBIN A2;

ARTICLE; BETA THALASSEMIA; BLOOD TRANSFUSION; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DEVELOPING COUNTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC COUNSELING; GENETIC RISK; HETEROZYGOTE DETECTION; HUMAN; HUMAN CELL; INDIA; MAJOR CLINICAL STUDY; MASS SCREENING; PRENATAL DIAGNOSIS; SCREENING;

BETA-THALASSEMIA; CHROMATOGRAPHY; DEVELOPING COUNTRIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEMOGLOBIN A2; HETEROZYGOTE DETECTION; HUMANS;

EID: 12844261653     PISSN: 08878013     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcla.20050     Document Type: Article

References (6)

1. Engvall E, Perlmann P. Enzyme linked immunosorbent assay, ELISA. III. Quantitation of specific antibodies by enzyme labelled anti-immunoglobulin in antigen coated tubes. J Immunol 1972;109:129-135.
2. Huisman THJ, Dozy AM. Studies on the heterogeneity of hemoglobin. J Chromatogr 1965;19:160-169.
3. Maheswari M, Arora S, Kabra M, Menon PSN. Carrier screening and prenatal diagnosis of β-thalassaemia. Indian Pediatr 1999;36:1119-1125.
4. 2: a novel method for β-thalassaemia screening in developing countries. J Immunoassay Immunochem 2004;25:135-146.
5. Grenet HE, Graver FA. Identification and quantitation of sickle cell hemoglobin with an enzyme-linked immunosorbent assay (ELISA). J Clin Lab Med 1980;96:597-605.
6. Weatherall DJ, Clegg JB. Inherited haemoglobin disorders: an increasing global health problem. Bull World Health Organ 2001;79:704-712.