Prognostic effect of insertion/deletion polymorphism of the ACE gene on renal and cardiovascular clinical outcomes in Chinese patients with type 2 diabetes

Diabetes Care

Volumn 28, Issue 2, 2005, Pages 348-354

  Wang, Ying ^a   Ng, Maggie C Y ^a   Wing, Yee So ^a   Tong, Peter C Y ^a   Ma, Ronald C W ^a   Chun, Chung Chow ^a   Cockram, Clive S ^a   Chan, Juliana C N ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; AGAR GEL ELECTROPHORESIS; AGED; ALLELE; ARTICLE; CEREBROVASCULAR ACCIDENT; CHINESE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE DELETION; GENE INSERTION; HEART FAILURE; HETEROZYGOTE DETECTION; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MULTIPLE REGRESSION; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYMERASE CHAIN REACTION; PROGNOSIS; REGRESSION ANALYSIS; REVASCULARIZATION;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; FEMALE; FOLLOW-UP STUDIES; GENE DELETION; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; PROGNOSIS; RISK FACTORS;

EID: 12844253012     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.28.2.348     Document Type: Article

References (38)

1. Peach MJ: Renin-angiotensin system: biochemistry and mechanisms of action. Physiol Rev 57:313-370, 1977
2. Corvol P, Williams TA, Soubrier F: Peptidyl dipeptidase A: angiotensin l-converting enzyme. Methods Enzyrnol 248:283-305, 1995
3. Ehlers MR, Fox EA, Strydom DJ, Riordan JF: Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme. Proc Natl Acad Sci U S A 86:7741-7745, 1989
4. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F: An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86:1343-1346, 1990
5. O'Donnell CJ, Lindpainmer K, Larson MG, Rao VS, Ordovas JM, Schaefer EJ, Myers RH, Levy D: Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study. Circulation 97:1766-1772, 1998
6. Dudley CR, Keavney B, Stratton IM, Turner RC, Ratcliffe PJ: U.K. Prospective Diabetes Study. XV: relationship of renin-angiotensin system gene polymorphisms with microalbuminuria in NIDDM. Kidney Int 48:1907-1911, 1995
7. Fujisawa T, Ikegami H, Shen GQ, Yamato E, Takekawa K, Nakagawa Y, Hamada Y, Ueda H, Rakugi H, Higaki J: Angiotensin I-converting enzyme gene polymorphism is associated with myocardial infarction, but not with retinopathy or nephropathy, in NIDDM. Diabetes Care 18:983-985, 1995
8. Fava S, Azzopardi J, Ellard S, Hattersley AT: ACE gene polymorphism as a prognostic indicator in patients with type 2 diabetes and established renal disease. Diabetes Care 24:2115-2120, 2001
9. Solini A, Dalla Vestra M, Saller A, Nosadini R, Crepaldi G, Fioretto P: The angiotensin-converting enzyme DD genotype is associated with glomerulopathy lesions in type 2 diabetes. Diabetes 51:251-255, 2002
10. Ringel J, Beige J, Kunz R, Distler A, Sharma AM: Genetic variants of the reninangiotensin system, diabetic nephropathy and hypertension. Diabetologia 40:193-199, 1997
11. Gutierrez C, Vendrell J, Pastor R, Llor C, Aguilar C, Broch M, Richart C: Angiotensin I-converting enzyme and angiotensinogen gene polymorphisms in non-insulin-dependent diabetes mellitus: lack of relationship with diabetic nephropathy and retinopathy in a Caucasian Mediterranean population. Metabolism 46:976-980, 1997
12. Young RP, Chan JC, Critchley JA, Poon E, Nicholls G, Cockram CS: Angiotensinogen T235 and ACE insertion/deletion polymorphisms associated with albuminuria in Chinese type 2 diabetic patients. Diabetes Care 21:431-437, 1998
13. Wong TY, Chan JC, Poon E, Li PK: Lack of association of angiotensin-converting enzyme (DD/II) and angiotensinogen M235T gene polymorphism with renal function among Chinese patients with type II diabetes. Am J Kidney Dis 33:1064-1070, 1999
14. Piwernetz K, Home PD, Snorgaard O, Antsiferov M, Staehr-Johansen K, Krans M, for the Diabetes Care Monitoring Group of the St. Vincent Declaration Steering Committee: Monitoring the targets of the St. Vincent Declaration and the implementation of quality management in diabetes care: the diabetes care initiative. Diabet Med 10:371-377, 1993
15. Mogensen CE, Vestbo E, Poulsen PL, Christiansen C, Damsgaard EM, Eiskjær H, FrØland A, Hansen KW, Nielsen S, Pedersen MM: Microalbuminuria and potential confounders. Diabetes Care 18: 572-581, 1995
16. Laakso M, Pyorala K: Age of onset and type of diabetes. Diabetes Care 8:114-117, 1985
17. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502, 1972
18. Maguire GA, Price CP: A continuous monitoring spectrophotometric method for the measurement of angiotensin-converting enzyme in human serum. Ann Clin Biochem 22:204-210, 1985
19. Cambien F, Poirier O, Lecerf L, Evans A, Cambou JP, Arveiler D, Luc G, Bard JM, Bara L, Ricard S, Tiret L, Amouyel P, Alhenc-Gelas F, Soubrier F: Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 359: 641-644, 1992
20. Tarnow L, Gluud C, Parving HH: Diabetic nephropathy and the insertion/deletion polymorphism of the angiotensin-converting enzyme gene. Nephrol Dial Transplant 13:1125-1130, 1998
21. Parving H-H, Østerby R, Ritz E: Diabetic nephropathy. In The Kidney. 6th ed. Brenner BM, Levine S, eds. Philadelphia, WB Saunders, 2000, p. 1731-1773
22. Seaquist ER, Goetz FC, Rich S, Barbosa J: Familial clustering of diabetic kidney disease: evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med 320: 1161-1165, 1989
23. Tiret L, Rigat B, Visvikis S, Breda C, Corvol P, Cambien F, Soubrier F: Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet 51: 197-205, 1992
24. Hall JE, Guyton AC, Jackson TE, Coleman TG, Lohmeier TE, Trippodo NC: Control of glomerular filtration rate by renin-angiotensin system. Am J Physiol 233:F366-F372, 1977
25. Soubrier F, Wei L, Hubert C, Clauser E, Alhenc-Gelas F, Corvol P: Molecular biology of the angiotensin I converting enzyme: II. Structure-function: gene polymorphism and clinical implications. J Hypertens 11: 599-604, 1993
26. Lieberman J, Sastre A: Serum angiotensin-converting enzyme: elevations in diabetes mellitus. Ann Intern Med 93:825-826, 1980
27. Chan JC, Nicholls MG, Cheung CK, Law LK, Swaminathan R, Cockram CS: Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM. Diabetes Care 18:1001-1006, 1995
28. Zatz R, Dunn BR, Meyer TW, Anderson S, Rennke HG, Brenner BM: Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. J Clin Invest 77:1925-1930, 1986
29. Ravid M, Brosh D, Levi Z, Bar-Dayan Y, Ravid D, Rachmani R: Use of enalapril to attenuate decline in renal function in normotensive, normoalbuminuric patients with type 2 diabetes mellitus: a randomized, controlled trial. Ann Intern Med 128: 982-988, 1998
30. Fuller JH, Stevens LK, Wang SL: Risk factors for cardiovascular mortality and morbidity: the WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia 44 (Suppl. 2):S54-S64, 2001
31. Thomas GN, Young RP, Tomlinson B, Woo KS, Sanderson JE, Critchley JA: Renin-angiotensin-aldosterone system gene polymorphisms and hypertension in Hong Kong Chinese. Clin Exp Hypertens 22:87-97, 2000
32. Takahashi K, Nakamura H, Kubota I, Takahashi N, Tomoike H: Association of ACE gene polymorphisms with coronary artery disease in a northern area of Japan. Jpn Heart J 36:557-564, 1995
33. Frost D, Pfohl M, Clemens P, Haring HU, Beischer W: Evaluation of the insertion/deletion ACE gene polymorphism as a risk factor for carotid artery imima-media thickening and hypertension in young type 1 diabetic patients. Diabetes Care 21: 836-840, 1998
34. Lindpaintner K, Pfeffer MA, Kreutz R, Stampfer MJ, Grodstein F, LaMotte F, Buring J, Hennekens CH: A prospective evaluation of an angictensin- converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med 332:706-711, 1995
35. Harrap SB, Tzourio C, Cambien F, Poirier O, Raoux S, Chalmers J. Chapman N, Colman S, Leguennec S, MacMahon S, Neal B, Ohkubo T, Woodward M: The ACE gene I/D polymorphism is not associated with the blood pressure and cardiovascular benefits of ACE inhibition. Hypertension 42:297-303, 2003
36. Ko YL, Ko YS, Wang SM, Chu PH, Teng MS, Cheng NJ, Chen WJ, Hsu TS, Kuo CT, Chiang CW, Lee YS: Angiotensinogen and angiotensin-I converting enzyme gene polymorphisms and the risk of coronary artery disease in Chinese. Hum Genet 100:210-214, 1997
37. Sanderson JE, Yu CM, Young RP, Shum IO, Wei S, Arumanayagam M, Woo KS: Influence of gene polymorphisms of the renin-angiotensin system on clinical outcome in heart failure among the Chinese. Am Heart J 137:653-637, 1999
38. Cambien F, Costerotisse O, Tiret L, Poirier O, Lecerf L, Gonzales MF, Evans A, Arveiler D, Cambou JP, Luc G, Rakotovao R, Ducimetiere P, Soubrier F, Alhenc-Gelas F: Plasma level and gene polymorphism of angiotensin-converting enzyme in relation to myocardial infarction. Circulation 90:669-676, 1994