The effect of herbal medicine Silybum marianum (L.) Gaertn. seed extract on galactose induced cataract formation in rat

Journal of Medicinal Plants

Volumn 3, Issue 12, 2004, Pages 58-63

  Huseini, H Fallah ^a   Zaree, A B ^b   Zarch, A Babaei ^c   Heshmat, R ^d  

^a Institute of Medicinal Plants Iran   (Iran)

^b BAQIYATALLAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antioxidant; Cataract; Galactose; Herbal medicine; Silymarin

Indexed keywords

ANTIOXIDANT; GALACTOSE; GLUTATHIONE; SILYBUM MARIANUM EXTRACT; SILYMARIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CATARACT; CATARACTOGENESIS; CELL MEMBRANE; CONTROLLED STUDY; HERBAL MEDICINE; MALE; NONHUMAN; PLANT SEED; RAT; SILYBUM MARIANUM;

EID: 12744273048     PISSN: 2717204X     EISSN: 27172058     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Taylor HR and Keeffe JE. World blindness: a 21st century perspective. Br J. Ophthalmol. 2001; 85(3): 261-6.
2. Roodhooft JM. Leading causes of blindness worldwide. Bull Soc Belge. Ophtalmol. 2002; 283: 19-25.
3. Harding JJ. Recent studies of risk factors and protective factors for cataract. Opin Ophthalmol. 1997; 8(1): 46-9.
4. West SK and Valmadrid CT. Epidemiology of risk factors for age-related cataract. Surv Ophthalmol. 1995; 39(4): 323-34.
5. Rotimi C, Daniel H, Zhou J, Obisesan A, Chen G, Chen Y and Amoah A. Prevalence and determinants of diabetic retinopathy and cataracts in West African type 2 diabetes patients. Ethn Dis. 2003; 13(2 Suppl 2): S110-7.
6. Boileau TW, Bray TM and Bomser JA. Ultraviolet radiation modulates nuclear factor kappa B activation in human lens epithelial cells. Biochem. Mol. Toxicol. 2003; 17(2): 108-13.
7. Giblin FJ. Glutathione: a vital lens antioxidant. J. Ocul. Pharmacol. Ther. 2000; 16(2): 121-35.
8. Srivastava SK, Lal AK, Ansari NH. Defense system of the lens against oxidative damage: effect of oxidative challenge on cataract formation in glutathione peroxidase deficient-acatalasemic mice. Exp. Eye. Res. 1980; 31(4): 425-33.
9. Richer S. Antioxidants and the eye. Int. Ophthalmol. Clin. 2000; 40(4): 1-16.
10. Wu SY and Leske MC. Antioxidants and cataract formation: a summary review. Int. Ophthalmol. Clin. 2000 Fall; 40(4):71-81. Exp. Eye. Res. 1999; 68(6): 747-55.
11. Wu SY and Leske MC. Antioxidants and cataract formation: a summary review. Int. Ophthalmol. Clin. 2000 Fall; 40(4):71-81. Exp. Eye. Res. 1999; 68(6): 747-55.
12. Ohta Y, Torii H, Yamasaki T, Niwa T, Majima Y and Ishiguro I. Preventive action of vitamin E-containing liposomes on cataractogenesis in young adult rats fed a 25% galactose diet. J. Ocul. Pharmacol. Ther. 1997; 13(6): 537-50.
13. Vogle G. Studies on pharmacodynamics, site and mechanism of action of silymarin the antihepatotoxic principale from silybum marianum (L.) Gaert. Arzneim Forsch. 1979; 25: 179-185.
14. Campos R, Garrido A. Silybin dihemsuccinate protects against glutathioine depletion and lipid peroxidation induced by acetaminophen on rat liver. Plant. Meidca. 1998; 55: 417-429.
15. Muzes G, Deak M. Effect of the bioflavonoids silybumarin on the in vitro activity and expression of superoxide dismutase (SOD) enzyme. Acta. Physiol. Hungarica. 1991; 78: 3-9.
16. Gupta SK, Joshi S, Tandon R, Mathur P. Topical aspirin provides protection against galactosemic cataract. Indian. J. Ophthalmol. 1997; 45(4): 221-5.
17. Skottova N, Krecman V, Walterova D and Ulrichova J. Effect of silymarin on serum cholesterol levels in rats. Acta. Univ. Palacki. Olomuc. Fac. Med. 1998; 141: 87-90.
18. Sedlak J and Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem. 1968; 25(1): 192-205.
19. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarburic acid reaction. Anal Biochem. 1979; 95: 351-358.
20. Gerster H. Antioxidant protection of the ageing macula. Age Ageing, 1991; 20: 60-69.
21. Niki E. Antioxidants in relation to lipid peroxidation. Chem. Phys. Lipids. 1987; 44: 227-253.
22. Gerster H. Antioxidant vitamins in cataract prevention. Z. Ernahrungswiss 1989; 28: 56-75.
23. Palla S, Kamala K, Bhanuprakash GR. Effect of curcumin on galactose-induced cataractogenesis in rats. Molecular Vision 2003; 9: 223-230.
24. Ohta Y, Yamasaki T, Niwa T, Goto H, Majima Y. Ishiguro I. Cataract development in 12-month-old rats fed a 25% galactose diet and its relation to osmotic stress and oxidative damage. Ophthalmic Res. 1999; 31(5): 321-31.