Ultraviolet radiation modulates nuclear factor kappa B activation in human lens epithelial cells

Journal of Biochemical and Molecular Toxicology

Volumn 17, Issue 2, 2003, Pages 108-113

  Boileau, Thomas W M ^a   Bray, Tammy M ^b   Bomser, Joshua A ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b OREGON STATE UNIVERSITY   (United States)

Author keywords

Cataract; Human lens epithelial cells; Nuclear factor kappa B; Ultraviolet radiation

Indexed keywords

I KAPPA B; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; NUCLEAR PROTEIN; PROTEIN P50; REGULATOR PROTEIN; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CATARACT; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; EPITHELIUM CELL; EYE DISEASE; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; LENS EPITHELIUM; MODULATION; PROTEIN PHOSPHORYLATION; RADIATION DOSE; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET C RADIATION; ULTRAVIOLET RADIATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPITHELIAL CELLS; HUMANS; LENS, CRYSTALLINE; NF-KAPPA B; PHOSPHORYLATION; TRANSLOCATION, GENETIC; ULTRAVIOLET RAYS;

EID: 0038324459     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbt.10067     Document Type: Article

References (37)

1. Balasubramanian D. Ultraviolet radiation and cataract. J Ocul Pharmacol Ther 2000;16:285-297.
2. Taylor HR, West SK, Rosenthal FS, Munoz B, Newland HS, Abbey H, Emmett EA. Effect of ultraviolet radiation on cataract formation. N Engl J Med 1988;319:1429-1433.
3. Taylor HR. Epidemiology of age-related cataract. Eye 1999;13:445-448.
4. Linetsky M, Ortwerth BJ. The generation of hydrogen peroxide by the UVA irradiation of human lens proteins. Photochem Photobiol. 1995;62:87-93.
5. Linetsky M, James HL, Ortwerth BJ. The generation of superoxide anion by the UVA irradiation of human lens proteins. Exp Eye Res 1996;63:67-74.
6. Zigman S, McDaniel T, Schultz JB, Reddan J, Meydani M. Damage to cultured lens epithelial cells of squirrels and rabbits by UV-A (99.9%) plus UV-B (0.1%) radiation and alpha tocopherol protection. Mol Cell Biochem 1995;143:35-46.
7. Sidjanin D, Zigman S, Reddan J. DNA damage and repair in rabbit lens epithelial cells following UVA radiation. Curr Eye Res 1993;12:773-781.
8. Rafferty NS, Zigman S, McDaniel T, Scholz DL. Near-UV radiation disrupts filamentous actin in lens epithelial cells. Cell Motil Cytoskeleton 1993;26:40-48.
9. Zigman S. Lens UVA photobiology, J Ocul Pharmacol Ther 2000;16:161-165.
10. Zigman S, McDaniel T, Schultz J, Reddan J. Effects of intermittent UVA exposure on cultured lens epithelial cells. Curr Eye Res 2000;20:95-100.
11. Linetsky M, Ortwerth BJ. Quantitation of the reactive oxygen species generated by the UVA irradiation of ascorbic acid-glycated lens proteins. Photochem Photobiol 1996;63:649-655.
12. Thannickal VJ, Fanburg BL. Reactive oxygen species in cell signaling. Am J Physiol Lung Cell Mol Physiol 2000;279:L1005-L1028.
13. Sauer H, Wartenberg M, Hescheler J. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 2001;11:173-186.
14. Hancock JT, Desikan R, Neill SJ. Role of reactive oxygen species in cell signalling pathways. Biochem Soc Trans 2001;29:345-350.
15. Lavrovsky Y, Chatterjee B, Clark RA, Roy AK. Role of redox-regulated transcription factors in inflammation, aging and age-related diseases. Exp Gerontol. 2000;35:521-532.
16. Barkett M, Gilmore TD. Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene 1999;18: 6910-6924.
17. Baeuerle PA, Henkel T. Function and activation of NF-κB in the immune system. Annual Rev Immunol 1994;12:141-179.
18. Dudek EJ, Shang F, Taylor A. H(2)O(2)-mediated oxidative stress activates NF-kappa B in lens epithelial cells. Free Radic Biol Med 2001;31:651-658.
19. Vile GF, Tanew-Ilitschew A, Tyrrell RM. Activation of NF-kappa B in human skin fibroblasts by the oxidative stress generated by UVA radiation. Photochem Photobiol 1995;62:463-468.
20. Nakano H, Gasparro FP, Uitto J. UVA-340 as energy source, mimicking natural sunlight, activates the transcription factor AP-1 in cultured fibroblasts: Evidence for involvement of protein kinase-C. Photochem Photobiol 2001;74:274-282.
21. Djavaheri-Mergny M, Gras MP, Mergny JL, Dubertret L. UV-A-induced decrease in nuclear factor-kappaB activity in human keratinocytes. Biochem J 1999;338:607-613.
22. Ibaraki N, Chen SC, Lin LR, Okamoto H, Pipas JM, Reddy VN. Human lens epithelial cell line. Exp Eye Res 1998;67:577-585.
23. Bomser JA. Selective induction of mitogen-activated protein kinases in human lens epithelial cells by ultraviolet radiation. J Biochem Mol Toxicol 2002;16:33-40.
24. McCarty C, Taylor HR. Light and risk for age-related eye diseases. In: Taylor A, editor. Nutritional and Environmental Influences on the Eye. New York: CRC Press; 1999. pp. 135-150.
25. Sliney DH. UV radiation ocular exposure dosimetry. J Photochem Photobiol B 1995;31:69-77.
26. Staal FJ, Anderson MT, Herzenberg LA. Redox regulation of activation of NF-kappa B transcription factor complex: Effects of N-acetylcysteine. Methods Enzymol 1995;252:168-174.
27. Pahl HL. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 1999;18:6853-6866.
28. Dumont A, Hehner SP, Hofmann TG, Ueffing M, Droge W, Schmitz ML. Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB. Oncogene 1999;18:747-757.
29. Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998;281:1680-1683.
30. Li N, Karin M. Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. Proc Natl Acad Sci USA 1998;95:13012-13017.
31. Shaulian E, Karin M. AP-1 in cell proliferation and survival. Oncogene 2001;20:2390-2400.
32. Djavaheri-Mergny M, Mergny JL, Bertrand F, Santus R, Maziere C, Dubertret L, Maziere JC. Ultraviolet-A induces activation of AP-1 in cultured human keratinocytes. FEBS Lett 1996;384:92-96.
33. Djavaheri-Mergny M, Dubertret L. UV-A-induced AP-1 activation requires the Raf/ERK pathway in human NCTC 2544 keratinocytes. Exp Dermatol 2001;10:204-210.
34. Baldwin AS Jr. Series introduction: The transcription factor NF-kappaB and human disease. J Clin Invest 2001;107:3-6.
35. Singh DP, Sueno T, Kikuchi T, Guru SC, Yu S, Horwitz J, Chylack LT Jr., Shinohara T. Antibodies to a microbial peptide sharing sequence homology with betaA3-crystallin damage lens epithelial cells in vitro and in vivo. Autoimmunity 1999;29:311-322.
36. Singh DP, Guru SC, Kikuchi T, Abe T, Shinohara T. Autoantibodies against beta-crystallins induce lens epithelial cell damage and cataract formation in mice. J Immunol 1995;155:993-999.
37. Angunawela, II. The role of autoimmune phenomena in the pathogenesis of cataract. Immunology 1987;61:363-368.