Donor age affects differentiation of rat ventral mesencephalic stem cells

Neuroscience Letters

Volumn 375, Issue 2, 2005, Pages 101-106

  O'Keeffe, Gerard W ^a   Sullivan, Aideen M ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Differentiation; Expansion; Neural stem cells; Rat; Transplantation; Ventral mesencephalon

Indexed keywords

AGE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN TISSUE; CELL COUNT; CELL TYPE; CELL VOLUME; CONTROLLED STUDY; DEGENERATIVE DISEASE; DONOR; DOPAMINERGIC NERVE CELL; EMBRYO; EXAMINATION; GESTATIONAL AGE; MACROGLIA; MESENCEPHALON; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; STEM CELL TRANSPLANTATION;

AGE FACTORS; ANIMALS; ASTROCYTES; BIOLOGICAL MARKERS; BRAIN TISSUE TRANSPLANTATION; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; DOPAMINE; MESENCEPHALON; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NEURONS; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY; SPHEROIDS, CELLULAR; STEM CELLS; SUBSTANTIA NIGRA; TISSUE DONORS; VENTRAL TEGMENTAL AREA;

EID: 12744265236     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.10.083     Document Type: Article

References (18)

1. R. Barker, and A. Johnson Nigral and striatal neurons J. Cohen G.P. Wilkin Neural Cell Culture 1995 Oxford University Press Oxford 25 39
2. S.A. Bayer, K.V. Wills, L.C. Triarhou, and B. Ghetti Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse Exp. Brain Res. 105 1995 191 199
3. M.K. Carpenter, X. Cui, Z.Y. Hu, J. Jackson, S. Sherman, A. Seiger, and L.U. Wahlberg In vitro expansion of a multipotent population of human neural progenitor cells Exp. Neurol. 158 1999 265 278
4. S.Y. Chow, J. Moul, C.A. Tobias, B.T. Himes, Y. Liu, M. Obrocka, L. Hodge, A. Tessler, and I. Fischer Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord Brain Res. 874 2000 87 106
5. F. Gage Mammalian neural stem cells Science 287 2000 1433 1438
6. C. Halfpenny, T. Benn, and N. Scolding Cell transplantation, myelin repair, and multiple sclerosis Lancet Neurol. 1 2002 31 40
7. U. Lendahl, L.B. Zimmerman, and R.D. McKay CNS stem cells express a new class of intermediate filament protein Cell 60 1990 585 595
8. K. Nakashima, T. Takizawa, W. Ochiai, M. Yanagisawa, T. Hisatsune, M. Nakafuku, K. Miyazono, T. Kishimoto, R. Kageyama, and T. Taga BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis Proc. Natl. Acad. Sci. U.S.A. 98 2001 5868 5873
9. G.W. O'Keeffe, M. Hanke, J. Pohl, and A.M. Sullivan Expression of growth differentiation factor-5 in the developing and adult rat brain Dev. Brain Res. 151 2004 199 202
10. T. Ostenfeld, E. Joly, Y.T. Tai, A. Peters, M. Caldwell, E. Jauniaux, and C.N. Svendsen Regional specification of rodent and human neurospheres Dev. Brain Res. 134 2002 43 55
11. A.E. Peaire, T. Takeshima, J.M. Johnston, K. Isoe, K. Nakashima, and J.W. Commissiong Production of dopaminergic neurons for cell therapy in the treatment of Parkinson's disease J. Neurosci. Methods 124 2003 61 74
12. B.A. Reynolds, and S.S. Weiss Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system Science 255 1992 1707 1710
13. F. Rossi, and E. Cattaneo Opinion: neural stem cell therapy for neurological diseases: dreams and reality Nat. Rev. Neurosci. 3 2002 401 409
14. M. Ruhnke, H. Ungefroren, G. Zehle, M. Bader, B. Kremer, and F. Fandrich Long-term culture and differentiation of rat embryonic stem cell-like cells into neuronal, glial, endothelial, and hepatic lineages Stem Cells 21 2003 428 436
15. L. Studer, V. Tabar, and R.D. McKay Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats Nat. Neurosci. 1 1998 290 295
16. C.N. Svendsen, J.W. Fawcett, C. Bentlage, and S.B. Dunnett Increased survival of rat EGF-generated CNS precursor cells using B27 supplemented medium. Exp. Brain Res. 102 1995 407 414
17. C.N. Svendsen, and A.G. Smith New prospects for human stem-cell therapy in the nervous system Trends Neurosci. 22 1999 357 364
18. S.Y. Yung, S. Gokhan, J. Jurcsak, A.E. Molero, J.J. Abrajano, and M.F. Mehler Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ventral forebrain progenitor species Proc. Natl. Acad. Sci. U.S.A. 99 2002 16273 16278