메뉴 건너뛰기




Volumn 7, Issue 1, 2005, Pages 98-105

Increased adiposity and reduced adipose tissue mRNA expression of uncoupling protein-2 in first-degree relatives of type 2 diabetic patients: Evidence for insulin stimulation of UCP-2 and UCP-3 gene expression in adipose tissue

Author keywords

Obesity; Relatives; Type 2 diabetes; UCP 2

Indexed keywords

INSULIN; MESSENGER RNA; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

EID: 12744253819     PISSN: 14628902     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2005.00365.x     Document Type: Article
Times cited : (15)

References (20)
  • 1
    • 0023851885 scopus 로고
    • Reduced rate of energy expenditure as a risk factor for body-weight gain
    • Ravussin E, Lillioja S, Knowler WC et al. Reduced rate of energy expenditure as a risk factor for body-weight gain. N Engl J Med 1988; 318: 467-472.
    • (1988) N. Engl. J. Med. , vol.318 , pp. 467-472
    • Ravussin, E.1    Lillioja, S.2    Knowler, W.C.3
  • 2
    • 0025292829 scopus 로고
    • The response to long-term overfeeding in identical twins
    • Bouchard C, Tremblay A, Despres JP et al. The response to long-term overfeeding in identical twins. N Engl J Med 1990; 322: 1477-1482.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1477-1482
    • Bouchard, C.1    Tremblay, A.2    Despres, J.P.3
  • 3
    • 0021198714 scopus 로고
    • Increased level of mRNA for the uncoupling protein in brown adipose tissue of rats during thermogenesis induced by cold exposure or norepinephrine infusion
    • Bouillaud F, Ricquier D, Mory G, Thibault J. Increased level of mRNA for the uncoupling protein in brown adipose tissue of rats during thermogenesis induced by cold exposure or norepinephrine infusion. J Biol Chem 1984; 259: 11583-11586.
    • (1984) J. Biol. Chem. , vol.259 , pp. 11583-11586
    • Bouillaud, F.1    Ricquier, D.2    Mory, G.3    Thibault, J.4
  • 4
    • 0031019249 scopus 로고    scopus 로고
    • Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia
    • Fleury C, Neverova M, Collins S et al. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat Genet 1997; 15: 269-272.
    • (1997) Nat. Genet. , vol.15 , pp. 269-272
    • Fleury, C.1    Neverova, M.2    Collins, S.3
  • 5
    • 0030988140 scopus 로고    scopus 로고
    • Uncoupling protein-3: A new member of the mitochondrial carrier family with tissue-specific expression
    • Boss O, Samec S, Paoloni-Giacobino A et al. Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett 1997; 408: 39-42.
    • (1997) FEBS Lett. , vol.408 , pp. 39-42
    • Boss, O.1    Samec, S.2    Paoloni-Giacobino, A.3
  • 6
    • 0031737797 scopus 로고    scopus 로고
    • Expression of mRNAs encoding uncoupling proteins in human skeletal muscle: Effects of obesity and diabetes
    • Bao S, Kennedy A, Wojciechowski B, Wallace P, Ganaway E, Garvey WT. Expression of mRNAs encoding uncoupling proteins in human skeletal muscle: effects of obesity and diabetes. Diabetes 1998; 47: 1935-1940.
    • (1998) Diabetes , vol.47 , pp. 1935-1940
    • Bao, S.1    Kennedy, A.2    Wojciechowski, B.3    Wallace, P.4    Ganaway, E.5    Garvey, W.T.6
  • 7
    • 0031809715 scopus 로고    scopus 로고
    • mRNA expression of the long and short forms of uncoupling protein-3 in obese and lean humans
    • Millet L, Vidal H, Larrouy D, Andreelli F, Laville M, Langin D. mRNA expression of the long and short forms of uncoupling protein-3 in obese and lean humans. Diabetologia 1998; 41: 829-832.
    • (1998) Diabetologia , vol.41 , pp. 829-832
    • Millet, L.1    Vidal, H.2    Larrouy, D.3    Andreelli, F.4    Laville, M.5    Langin, D.6
  • 8
    • 0031844583 scopus 로고    scopus 로고
    • Reduced gene expression of UCP2 but not UCP3 in skeletal muscle of human obese subjects
    • Nordfors L, Hoffstedt J, Nyberg B et al. Reduced gene expression of UCP2 but not UCP3 in skeletal muscle of human obese subjects. Diabetologia 1998; 41: 935-939.
    • (1998) Diabetologia , vol.41 , pp. 935-939
    • Nordfors, L.1    Hoffstedt, J.2    Nyberg, B.3
  • 9
    • 0031816020 scopus 로고    scopus 로고
    • Uncoupling protein-2 gene: Reduced mRNA expression in intraperitoneal adipose tissue of obese humans
    • Oberkofler H, Liu YM, Esterbauer H, Hell E, Krempler F, Patsch W. Uncoupling protein-2 gene: reduced mRNA expression in intraperitoneal adipose tissue of obese humans. Diabetologia 1998; 41: 940-946.
    • (1998) Diabetologia , vol.41 , pp. 940-946
    • Oberkofler, H.1    Liu, Y.M.2    Esterbauer, H.3    Hell, E.4    Krempler, F.5    Patsch, W.6
  • 11
    • 0031437096 scopus 로고    scopus 로고
    • Increased uncoupling protein-2 and -3 mRNA expression during fasting in obese and lean humans
    • Millet L, Vidal H, Andreelli F et al. Increased uncoupling protein-2 and -3 mRNA expression during fasting in obese and lean humans. J Clin Invest 1997; 100: 2665-2670.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2665-2670
    • Millet, L.1    Vidal, H.2    Andreelli, F.3
  • 12
    • 0032714213 scopus 로고    scopus 로고
    • Lack of skeletal muscle uncoupling protein 2 and 3 mRNA induction during fasting in type-2 diabetic subjects
    • Vidal H, Langin D, Andreelli F, Millet L, Larrouy D, Laville M. Lack of skeletal muscle uncoupling protein 2 and 3 mRNA induction during fasting in type-2 diabetic subjects. Am J Physiol 1999; 277: E830-E837.
    • (1999) Am. J. Physiol. , vol.277
    • Vidal, H.1    Langin, D.2    Andreelli, F.3    Millet, L.4    Larrouy, D.5    Laville, M.6
  • 13
    • 0032947454 scopus 로고    scopus 로고
    • Screening for variants of the uncoupling protein 2 gene in Japanese patients with non-insulin-dependent diabetes mellitus
    • Shiinoki T, Suehiro, T, Ikeda Y et al. Screening for variants of the uncoupling protein 2 gene in Japanese patients with non-insulin-dependent diabetes mellitus. Metabolism 1999; 48: 581-584.
    • (1999) Metabolism , vol.48 , pp. 581-584
    • Shiinoki, T.1    Suehiro, T.2    Ikeda, Y.3
  • 14
    • 9844232617 scopus 로고    scopus 로고
    • Mutational analysis of the coding region of the uncoupling protein 2 gene in obese NIDDM patients: Impact of a common amino acid polymorphism on juvenile and maturity onset forms of obesity and insulin resistance
    • Urhammer SA, Dalgaard LT, Sorensen TI et al. Mutational analysis of the coding region of the uncoupling protein 2 gene in obese NIDDM patients: impact of a common amino acid polymorphism on juvenile and maturity onset forms of obesity and insulin resistance. Diabetologia 1997; 40: 1227-1230.
    • (1997) Diabetologia , vol.40 , pp. 1227-1230
    • Urhammer, S.A.1    Dalgaard, L.T.2    Sorensen, T.I.3
  • 15
    • 0030731492 scopus 로고    scopus 로고
    • Uncoupling protein 2 region on chromosome 11q13 is not linked to markers of obesity in familial type 2 diabetes
    • Elbein SC, Leppert M, Hasstedt S. Uncoupling protein 2 region on chromosome 11q13 is not linked to markers of obesity in familial type 2 diabetes. Diabetes 1997; 46: 2105-2107.
    • (1997) Diabetes , vol.46 , pp. 2105-2107
    • Elbein, S.C.1    Leppert, M.2    Hasstedt, S.3
  • 16
    • 0029115771 scopus 로고
    • Relationship between sex hormones, body composition and metabolic risk parameters in premenopausal women
    • Pedersen SB, Borglum JD, Brixen K, Richelsen B. Relationship between sex hormones, body composition and metabolic risk parameters in premenopausal women. Eur J Endocrinol 1995; 133: 200-206.
    • (1995) Eur. J. Endocrinol. , vol.133 , pp. 200-206
    • Pedersen, S.B.1    Borglum, J.D.2    Brixen, K.3    Richelsen, B.4
  • 17
    • 0029589658 scopus 로고
    • Growth hormone treatment of obese premenopausal women: Effects on isolated adipocyte metabolism
    • Pedersen SB, Børglum JD, Jørgensen JOL, Richelsen B. Growth hormone treatment of obese premenopausal women: Effects on isolated adipocyte metabolism. Endocrinol Metab 1995; 2: 251-258.
    • (1995) Endocrinol. Metab. , vol.2 , pp. 251-258
    • Pedersen, S.B.1    Børglum, J.D.2    Jørgensen, J.O.L.3    Richelsen, B.4
  • 18
    • 0028151418 scopus 로고
    • Monitoring mRNA expression by polymerase chain reaction: The 'primer-dropping' method
    • Wong H, Anderson WD, Cheng T, Riabowol KT. Monitoring mRNA expression by polymerase chain reaction: the 'primer-dropping' method. Anal Biochem 1994; 223: 251-258.
    • (1994) Anal. Biochem. , vol.223 , pp. 251-258
    • Wong, H.1    Anderson, W.D.2    Cheng, T.3    Riabowol, K.T.4
  • 20
    • 0034800518 scopus 로고    scopus 로고
    • Insulin and contraction directly stimulate UCP2 and UCP3 mRNA expression in rat skeletal muscle in vitro
    • Pedersen SB, Lund S, Buhl ES, Richelsen B. Insulin and contraction directly stimulate UCP2 and UCP3 mRNA expression in rat skeletal muscle in vitro. Biochem Biophys Res Commun 2001; 283: 19-25.
    • (2001) Biochem. Biophys. Res. Commun. , vol.283 , pp. 19-25
    • Pedersen, S.B.1    Lund, S.2    Buhl, E.S.3    Richelsen, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.