SCOPUS 정보 검색 플랫폼

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 61, Issue , 1996, Pages 551-558

The role of presenilin 1 in the genetics of Alzheimer's disease

(14) Clark, R F a Hutton, M b Talbot, C a Wragg, M a Lendon, C a Busfield, F a Han, S W a Perez Tur, J b Adams, M c Fuldner, R c Roberts, G d Karran, E d Hardy, J b Goate, A a

a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE (United States)

b MAYO CLINIC (United States)

c J CRAIG VENTER INSTITUTE (United States)

d GLAXOSMITHKLINE (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; CONFERENCE PAPER; GENE MUTATION; GENETICS; HUMAN; PATHOGENESIS; PRIORITY JOURNAL; RISK FACTOR; ALTERNATIVE RNA SPLICING; ARTICLE; GENE EXPRESSION; GENE MAPPING; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; NONHUMAN; PROTEIN FUNCTION;

PRESENILIN 1; PRESENILIN 2;

EID: 12644298659 PISSN: 00917451 EISSN: None Source Type: Book Series
DOI: 10.1101/sqb.1996.061.01.055 Document Type: Conference Paper

Times cited : (9)

References (65)

1
- 0029664568
- Mutation analysis of presenilin 1 gene in Alzheimer's disease
- Boteva, K., M. Vitek, H. Mitsuda, H. de Silva, P.-T. Xu, G. Small, and J.R, Gilbert. 1996. Mutation analysis of presenilin 1 gene in Alzheimer's disease. Lancet 347: 130.
- (1996) Lancet , vol.347 , pp. 130
- Boteva, K.¹ Vitek, M.² Mitsuda, H.³ De Silva, H.⁴ Xu, P.-T.⁵ Small, G.⁶ Gilbert, J.R.⁷

2
- 16144367382
- Presenilin 1 polymorphism and Alzheimer's disease
- Bouras, C., P. Giannakouplos, J. Shioi, N. Tezapsidis, and N. Robakis. 1996. Presenilin 1 polymorphism and Alzheimer's disease. Lancet 347: 1185.
- (1996) Lancet , vol.347 , pp. 1185
- Bouras, C.¹ Giannakouplos, P.² Shioi, J.³ Tezapsidis, N.⁴ Robakis, N.⁵

3
- 0028812820
- Mutations of the presenilin 1 gene in families with early-onset Alzheimer's disease
- Campion, D., J.-M. Flaman, A. Brice, D. Hannequin, B. Dubois, C. Martin, V. Moreau, F. Charbonnier, O. Didierjean, S. Tardieu, C. Penet, M. Puel, F. Pasquier, F. Le Doze, G. Bellis, A. Calenda, R. Heilig, M. Martinez, J. Mallet, M. Bellis, F. Clerget-Darpoux, Y. Agid, and T. Frebourg. 1995. Mutations of the presenilin 1 gene in families with early-onset Alzheimer's disease. Hum. Mol. Genet. 4: 2373.
- (1995) Hum. Mol. Genet. , vol.4 , pp. 2373
- Campion, D.¹ Flaman, J.-M.² Brice, A.³ Hannequin, D.⁴ Dubois, B.⁵ Martin, C.⁶ Moreau, V.⁷ Charbonnier, F.⁸ Didierjean, O.⁹ Tardieu, S.¹⁰ Penet, C.¹¹ Puel, M.¹² Pasquier, F.¹³ Le Doze, F.¹⁴ Bellis, G.¹⁵ Calenda, A.¹⁶ Heilig, R.¹⁷ Martinez, M.¹⁸ Mallet, J.¹⁹ Bellis, M.²⁰ more..

4
- 0026075602
- Early onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene
- Chartier-Harlin, M.-C., F. Crawford, H. Houlden, A. Warren, D. Hughes, L. Fidani, A. Goate, M. Rossor, P. Roques, J. Hardy, and M. Mullan. 1991. Early onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene. Nature 353: 844.
- (1991) Nature , vol.353 , pp. 844
- Chartier-Harlin, M.-C.¹ Crawford, F.² Houlden, H.³ Warren, A.⁴ Hughes, D.⁵ Fidani, L.⁶ Goate, A.⁷ Rossor, M.⁸ Roques, P.⁹ Hardy, J.¹⁰ Mullan, M.¹¹

5
- 0028099612
- Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation
- Citron, M., C. Vigo-Pelfrey, D.B. Teplow, C. Miller, D. Schenk, J. Johnston, B. Winblad, N. Venizelos, L. Lannfelt, D.J. Selkoe. 1994. Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation. Proc. Natl. Acad. Sci. 91: 11993.
- (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 11993
- Citron, M.¹ Vigo-Pelfrey, C.² Teplow, D.B.³ Miller, C.⁴ Schenk, D.⁵ Johnston, J.⁶ Winblad, B.⁷ Venizelos, N.⁸ Lannfelt, L.⁹ Selkoe, D.J.¹⁰

6
- 0029125478
- A yeast artificial chromosome contig from human chromosome 14q24 spanning the Alzheimer's disease locus, AD3
- Clark, R.F., M. Cruts, K. Korenblat, C. He, C. Talbot, C. Van Broeckhoven, and A. M. Goate. 1995a. A yeast artificial chromosome contig from human chromosome 14q24 spanning the Alzheimer's disease locus, AD3. Hum. Mol. Genet. 4: 1347.
- (1995) Hum. Mol. Genet. , vol.4 , pp. 1347
- Clark, R.F.¹ Cruts, M.² Korenblat, K.³ He, C.⁴ Talbot, C.⁵ Van Broeckhoven, C.⁶ Goate, A.M.⁷

7
- 0029115555
- The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families
- Clark, R.F., M. Hutton, R.A. Fuldner, S. Froelich, E. Karran, C. Talbot, R. Crook, C. Lendon, G. Prihar, C. He, K. Korenblat, A. Martinez, M. Wragg, F. Busfield, M. I. Behrens, A. Myers, J. Norton, J.C. Morris, N. Mehta, C. Pearson, S. Lincoln, M. Baker, K. Duff, C. Zehr, J. Perez-Tur, H. Houlden, A. Ruiz, J. Ossa, F. Lapera, M. Arcos, L. Madrigal, J. Collinge, C. Humphreys, T. Asworth, S. Sarner, N. Fox, R. Harvey, A. Kennedy, P. Roques, R.T. Cline, C.A. Philips, J.C. Venter, L. Forsell, K. Axelman, L. Lilius, J. Johnston, R. Cowburn, M. Viitanen, B. Winblad, K. Kosik, M. Haltia, M. Poyhonen, D. Dickson, D. Mann, D. Neary, J. Snowden, P. Lantos, L. Lannfelt, M. Rossor, G.W. Roberts, M.D. Adams, J. Hardy, and A.M. Goate. 1995b. The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Nat. Genet. 11: 219.
- (1995) Nat. Genet. , vol.11 , pp. 219
- Clark, R.F.¹ Hutton, M.² Fuldner, R.A.³ Froelich, S.⁴ Karran, E.⁵ Talbot, C.⁶ Crook, R.⁷ Lendon, C.⁸ Prihar, G.⁹ He, C.¹⁰ Korenblat, K.¹¹ Martinez, A.¹² Wragg, M.¹³ Busfield, F.¹⁴ Behrens, M.I.¹⁵ Myers, A.¹⁶ Norton, J.¹⁷ Morris, J.C.¹⁸ Mehta, N.¹⁹ Pearson, C.²⁰ more..

8
- 0027194791
- Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
- Corder, E.H., A.M. Saunders, W.J. Strittmatter, D.E. Schmechel, P.C. Gaskell, G.W. Small, A.D. Roses, J.L. Haines, and M.A. Pericak-Vance. 1993. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261: 921.
- (1993) Science , vol.261 , pp. 921
- Corder, E.H.¹ Saunders, A.M.² Strittmatter, W.J.³ Schmechel, D.E.⁴ Gaskell, P.C.⁵ Small, G.W.⁶ Roses, A.D.⁷ Haines, J.L.⁸ Pericak-Vance, M.A.⁹

9
- 0028305380
- Protective effect of apolipoprotein e type 2 allele for late onset Alzheimer disease
- Corder, E.H., A.M. Saunders, N.J. Risen, W.J. Strittmatter, D.E. Schmechel, P.C. Gaskel, Jr., J.B. Rimmler, P.A. Locke, P.M. Conneally, K.E. Schmader, G.W. Small, A. D. Roses, J.L. Haines, and M.A. Pericak-Vance. 1994. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat. Genet. 7: 180.
- (1994) Nat. Genet. , vol.7 , pp. 180
- Corder, E.H.¹ Saunders, A.M.² Risen, N.J.³ Strittmatter, W.J.⁴ Schmechel, D.E.⁵ Gaskel Jr., P.C.⁶ Rimmler, J.B.⁷ Locke, P.A.⁸ Conneally, P.M.⁹ Schmader, K.E.¹⁰ Small, G.W.¹¹ Roses, A.D.¹² Haines, J.L.¹³ Pericak-Vance, M.A.¹⁴

10
- 0029149641
- Genetic and physical characterization of the early-onset Alzheimer's disease AD3 locus on chromosome 14q24.3
- Cruts, M., H. Backhovens, J. Theuns, R.F. Clark, D. Le Paslier, J. Weissenbach, A.M. Goate, J.-J. Martin, and C. Van Broeckhoven. 1995a. Genetic and physical characterization of the early-onset Alzheimer's disease AD3 locus on chromosome 14q24.3. Hum. Mol. Genet. 4: 1355.
- (1995) Hum. Mol. Genet. , vol.4 , pp. 1355
- Cruts, M.¹ Backhovens, H.² Theuns, J.³ Clark, R.F.⁴ Le Paslier, D.⁵ Weissenbach, J.⁶ Goate, A.M.⁷ Martin, J.-J.⁸ Van Broeckhoven, C.⁹

11
- 0028861041
- Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3
- Cruts, M., H. Backhovens, S.-Y. Wang, G. Van Gassen, J. Theuns, C. De Jonghe, A. Wehnert, J. De Voecht, G. De Winter, P. Cras, M. Bruyland, N. Datson, J. Weissenbach, J.T. den Dunnen, J-J. Martin, L. Hendriks, and C. Van Broeckhoven. 1995b. Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3. Hum. Mol. Genet. 4: 2363.
- (1995) Hum. Mol. Genet. , vol.4 , pp. 2363
- Cruts, M.¹ Backhovens, H.² Wang, S.-Y.³ Van Gassen, G.⁴ Theuns, J.⁵ De Jonghe, C.⁶ Wehnert, A.⁷ De Voecht, J.⁸ De Winter, G.⁹ Cras, P.¹⁰ Bruyland, M.¹¹ Datson, N.¹² Weissenbach, J.¹³ Den Dunnen, J.T.¹⁴ Martin, J.-J.¹⁵ Hendriks, L.¹⁶ Van Broeckhoven, C.¹⁷

12
- 0025295039
- Cleavage of amyloid beta peptide during constitutive processing of its precursor
- Esch, F.S., P.S. Keim, E.C. Beattie, R.W. Blacher, A. Culwell, T. Oltersdorf, D. McClure, and P.J. Ward. 1990. Cleavage of amyloid beta peptide during constitutive processing of its precursor. Science 248: 1122.
- (1990) Science , vol.248 , pp. 1122
- Esch, F.S.¹ Keim, P.S.² Beattie, E.C.³ Blacher, R.W.⁴ Culwell, A.⁵ Oltersdorf, T.⁶ McClure, D.⁷ Ward, P.J.⁸

13
- 0026879836
- Screening for mutations in the open reading frame and promoter of the β-amyloid precursor protein gene in familial Alzheimer's disease: Identification of a further family with APP717 Val→ Ile
- Fidani, L., K. Rooke, M.-C. Chartier-Harlin, D. Hughes, R. Tanzi, M. Mullan, P. Roques, M. Rossor, J. Hardy, and A.M. Goate. 1992. Screening for mutations in the open reading frame and promoter of the β-amyloid precursor protein gene in familial Alzheimer's disease: Identification of a further family with APP717 Val→ Ile. Hum. Mol. Genet. 1: 165.
- (1992) Hum. Mol. Genet. , vol.1 , pp. 165
- Fidani, L.¹ Rooke, K.² Chartier-Harlin, M.-C.³ Hughes, D.⁴ Tanzi, R.⁵ Mullan, M.⁶ Roques, P.⁷ Rossor, M.⁸ Hardy, J.⁹ Goate, A.M.¹⁰

14
- 0028985574
- Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
- Games, D., D. Adams, R. Alessandrini, R. Barbour, P. Berthelette, C. Blackwell, T. Carr, J. Clemens, T. Donaldson, F. Gillespie, T. Guido, S. Hagopian, K. Johnson-Wood, K. Khan, M. Lee, P. Leibowitz, T. Lieberburg, S. Little, E. Masliah, M. Montoya-Zavala, L. Mucke, L. Paganini, E. Penniman, M. Power, D. Schenk, P. Seubert, B. Snyder, F. Soriano, H. Tan, J. Vitale, S. Wadsworth, B. Wolozin, and J. Zhao. 1995. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373: 523.
- (1995) Nature , vol.373 , pp. 523
- Games, D.¹ Adams, D.² Alessandrini, R.³ Barbour, R.⁴ Berthelette, P.⁵ Blackwell, C.⁶ Carr, T.⁷ Clemens, J.⁸ Donaldson, T.⁹ Gillespie, F.¹⁰ Guido, T.¹¹ Hagopian, S.¹² Johnson-Wood, K.¹³ Khan, K.¹⁴ Lee, M.¹⁵ Leibowitz, P.¹⁶ Lieberburg, T.¹⁷ Little, S.¹⁸ Masliah, E.¹⁹ Montoya-Zavala, M.²⁰ more..

15
- 0026088977
- Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
- Goate, A.M., M.-C. Chartier Harlin, M. Mullan, J. Brown, F. Crawford, L. Fidani, L. Giuffra, A. Haynes, N. Irving, L. James, R. Mant, P. Newton, K. Rooke, P. Roques, C. Talbot, M. Pericak-Vance, A. Roses, R. Williamson, M. Rossor, M. Owen, and J. Hardy. 1991. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349: 704.
- (1991) Nature , vol.349 , pp. 704
- Goate, A.M.¹ Chartier Harlin, M.-C.² Mullan, M.³ Brown, J.⁴ Crawford, F.⁵ Fidani, L.⁶ Giuffra, L.⁷ Haynes, A.⁸ Irving, N.⁹ James, L.¹⁰ Mant, R.¹¹ Newton, P.¹² Rooke, K.¹³ Roques, P.¹⁴ Talbot, C.¹⁵ Pericak-Vance, M.¹⁶ Roses, A.¹⁷ Williamson, R.¹⁸ Rossor, M.¹⁹ Owen, M.²⁰ Hardy, J.²¹ more..

16
- 0023132387
- Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease
- Goldgaber, D., M.I. Lerman, O.W. McBride, U. Saffiotti, and D.C. Gajdusek. 1987. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science 235: 877.
- (1987) Science , vol.235 , pp. 877
- Goldgaber, D.¹ Lerman, M.I.² McBride, O.W.³ Saffiotti, U.⁴ Gajdusek, D.C.⁵

17
- 0028961402
- Apotipoprotein e genotypes and Alzheimer's disease in a community study of elderly African Americans
- Hendrie, H.C., K.S. Hall, S. Hui, F.W. Unverzagt, C.E. Yu, D.K. Lahiri, A. Sahota, M. Farlow, B. Musick, C.A. Class, A. Brashear, V. E. Burdine, B.O. Osuntokun, A.O. Ogunniyi, O. Gureje, O. Baiyewu, and G.D. Schellenberg. 1995. Apotipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann. Neurol. 37: 118.
- (1995) Ann. Neurol. , vol.37 , pp. 118
- Hendrie, H.C.¹ Hall, K.S.² Hui, S.³ Unverzagt, F.W.⁴ Yu, C.E.⁵ Lahiri, D.K.⁶ Sahota, A.⁷ Farlow, M.⁸ Musick, B.⁹ Class, C.A.¹⁰ Brashear, A.¹¹ Burdine, V.E.¹² Osuntokun, B.O.¹³ Ogunniyi, A.O.¹⁴ Gureje, O.¹⁵ Baiyewu, O.¹⁶ Schellenberg, G.D.¹⁷

18
- 0026879650
- Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the β-amyloid precursor protein gene
- Hendriks, L., C. van Duijn, P. Cras, M. Cruts, W. Van Hul, F. van Harskamp, A. Warren, M. McGinnis, S. Antonorakis, and C. Van Broeckhoven. 1992. Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the β-amyloid precursor protein gene. Nat. Genet. 1: 218.
- (1992) Nat. Genet. , vol.1 , pp. 218
- Hendriks, L.¹ Van Duijn, C.² Cras, P.³ Cruts, M.⁴ Van Hul, W.⁵ Van Harskamp, F.⁶ Warren, A.⁷ McGinnis, M.⁸ Antonorakis, S.⁹ Van Broeckhoven, C.¹⁰

19
- 0017734459
- The genetics of Alzheimer's disease: Associations with hematologic malignancy and Down syndrome
- Heston, L. and A. Mastri. 1977. The genetics of Alzheimer's disease: Associations with hematologic malignancy and Down syndrome. Arch. Gen. Psychiatry 34: 976.
- (1977) Arch. Gen. Psychiatry , vol.34 , pp. 976
- Heston, L.¹ Mastri, A.²

20
- 16144367382
- Presenilin 1 polymorphism and Alzheimer's disease
- Higuchi, S., T. Muramatsu, S. Matsushita, H. Arai, and H. Sasaki. 1996. Presenilin 1 polymorphism and Alzheimer's disease. Lancet 347: 1185.
- (1996) Lancet , vol.347 , pp. 1185
- Higuchi, S.¹ Muramatsu, T.² Matsushita, S.³ Arai, H.⁴ Sasaki, H.⁵

21
- 9344237637
- A complete analysis of the presenilin 1 gene in a series of families with Alzheimer's disease with a mean age of onset below 60 years: Identification of further mutations
- Hutton, M., F. Busfield, M. Wragg, R. Crook, J. Perez-Tur, R.F. Clark, G. Prihar, C. Talbot, H. Phillips, K. Wright, M. Baker, C. Lendon, K. Duff, A. Martinez, H. Houlden, J.C. Morris, N. Fox, R. Harvey, A. Kennedy, P. Roques, P. Lantos, A. Nichols, E. Karran, G. Roberts, J.C. Venter, M. Adams, R.T. Cline, C.A. Philips, R. Fuldner, M. Rossor, J. Hardy, and A.M. Goate. 1996. A complete analysis of the presenilin 1 gene in a series of families with Alzheimer's disease with a mean age of onset below 60 years: Identification of further mutations. NeuroReport 7: 801.
- (1996) NeuroReport , vol.7 , pp. 801
- Hutton, M.¹ Busfield, F.² Wragg, M.³ Crook, R.⁴ Perez-Tur, J.⁵ Clark, R.F.⁶ Prihar, G.⁷ Talbot, C.⁸ Phillips, H.⁹ Wright, K.¹⁰ Baker, M.¹¹ Lendon, C.¹² Duff, K.¹³ Martinez, A.¹⁴ Houlden, H.¹⁵ Morris, J.C.¹⁶ Fox, N.¹⁷ Harvey, R.¹⁸ Kennedy, A.¹⁹ Roques, P.²⁰ more..

22
- 0026686822
- Molecular and prospective phenotypic characterization of a pedigree with familial Alzheimer's disease and a missense mutation in codon 717 of the β-amyloid precursor protein gene
- Karlinsky, H., G. Vaula, J.L. Haines, J. Ridgley, C. Bergeron, M. Mortilla, R.G. Tupler, M.E. Percy, Y. Robitaille, N.E. Noldy, T. Yip, R.E. Tanzi, J.F. Gusella, R. Becker, J.M. Berg, D.R. Crapper-McLachlan, and P.M. St. George-Hyslop. 1992. Molecular and prospective phenotypic characterization of a pedigree with familial Alzheimer's disease and a missense mutation in codon 717 of the β-amyloid precursor protein gene. Neurology 42: 1445.
- (1992) Neurology , vol.42 , pp. 1445
- Karlinsky, H.¹ Vaula, G.² Haines, J.L.³ Ridgley, J.⁴ Bergeron, C.⁵ Mortilla, M.⁶ Tupler, R.G.⁷ Percy, M.E.⁸ Robitaille, Y.⁹ Noldy, N.E.¹⁰ Yip, T.¹¹ Tanzi, R.E.¹² Gusella, J.F.¹³ Becker, R.¹⁴ Berg, J.M.¹⁵ Crapper-McLachlan, D.R.¹⁶ St George-Hyslop, P.M.¹⁷

23
- 16144367382
- Presenilin 1 polymorphism and Alzheimer's disease
- Kehoe, P., J. Williams, S. Lovestone, G. Wilcock, and M. J. Owen. 1996. Presenilin 1 polymorphism and Alzheimer's disease. Lancet 347: 1185.
- (1996) Lancet , vol.347 , pp. 1185
- Kehoe, P.¹ Williams, J.² Lovestone, S.³ Wilcock, G.⁴ Owen, M.J.⁵

24
- 13344282063
- Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells
- Kovacs, D.M., H.J. Fausett, K.J. Page, T.-W. Kim, R.D. Moir, D.E. Merriam, R.D. Hollister, O.G. Hallmark, R. Mancini, K.M. Felsenstein, B.T. Hyman, R.E. Tanzi, and W. Wasco. 1996. Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nat. Med. 2: 224.
- (1996) Nat. Med. , vol.2 , pp. 224
- Kovacs, D.M.¹ Fausett, H.J.² Page, K.J.³ Kim, T.-W.⁴ Moir, R.D.⁵ Merriam, D.E.⁶ Hollister, R.D.⁷ Hallmark, O.G.⁸ Mancini, R.⁹ Felsenstein, K.M.¹⁰ Hyman, B.T.¹¹ Tanzi, R.E.¹² Wasco, W.¹³

25
- 0029116848
- Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene
- Levitan, D. and I. Greenwald. 1995. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377: 351.
- (1995) Nature , vol.377 , pp. 351
- Levitan, D.¹ Greenwald, I.²

26
- 0025296269
- Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type
- Levy, E., M.D. Carman, I.J. Fernandez Madrid, M.D. Power, I. Lieberburg, S.G. van Duinen, G.T. Bots, W. Luyendijk, and B. Frangione. 1990. Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Science 248: 1124.
- (1990) Science , vol.248 , pp. 1124
- Levy, E.¹ Carman, M.D.² Fernandez Madrid, I.J.³ Power, M.D.⁴ Lieberburg, I.⁵ Van Duinen, S.G.⁶ Bots, G.T.⁷ Luyendijk, W.⁸ Frangione, B.⁹

27
- 0029150716
- A familial Alzheimer's disease locus on chromosome 1
- Levy-Lahad, E., E.M. Wijsman, E. Nemens, L. Anderson, K.A.B. Goddard, J.L. Weber, T.D. Bird, and G.D. Schellenberg. 1995a. A familial Alzheimer's disease locus on chromosome 1. Science 269: 970.
- (1995) Science , vol.269 , pp. 970
- Levy-Lahad, E.¹ Wijsman, E.M.² Nemens, E.³ Anderson, L.⁴ Goddard, K.A.B.⁵ Weber, J.L.⁶ Bird, T.D.⁷ Schellenberg, G.D.⁸

28
- 0029087026
- Candidate gene for the chromosome 1 familial Alzheimer's disease locus
- Levy-Lahad, E., W. Wasco, P. Poorkaj, D.M. Romano, J. Oshima, W.H. Pettingell, C. Yu, P.D. Jondro, S.D. Schmidt, K. Wang, A.C. Crowley, Y-H. Fu, S.Y. Guenette, D. Galas, E. Nemens, E.M. Wijsman, T.D. Bird, G.D. Schellenberg, and R.E. Tanzi. 1995b. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269: 973.
- (1995) Science , vol.269 , pp. 973
- Levy-Lahad, E.¹ Wasco, W.² Poorkaj, P.³ Romano, D.M.⁴ Oshima, J.⁵ Pettingell, W.H.⁶ Yu, C.⁷ Jondro, P.D.⁸ Schmidt, S.D.⁹ Wang, K.¹⁰ Crowley, A.C.¹¹ Fu, Y.-H.¹² Guenette, S.Y.¹³ Galas, D.¹⁴ Nemens, E.¹⁵ Wijsman, E.M.¹⁶ Bird, T.D.¹⁷ Schellenberg, G.D.¹⁸ Tanzi, R.E.¹⁹

29
- 0028816355
- Apolipoprotein e and Alzheimer's disease: Ethnic variation in genotypic risk
- Maestre, G., R. Ottmann, Y. Stern, B. Gurland, M. Chun, M-X. Tang, M. Shelanski, B. Tycko, and R. Mayeux. 1995. Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotypic risk. Ann. Neurol. 37: 254.
- (1995) Ann. Neurol. , vol.37 , pp. 254
- Maestre, G.¹ Ottmann, R.² Stern, Y.³ Gurland, B.⁴ Chun, M.⁵ Tang, M.-X.⁶ Shelanski, M.⁷ Tycko, B.⁸ Mayeux, R.⁹

30
- 0027339923
- The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease
- Mayeux, R., Y. Stern, R. Ottman, T.K. Tatemichi, M. Tang, G. Maestre, C. Nagai, B. Tycko, and H. Ginsberg. 1993. The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease. Ann. Neurol. 34: 752.
- (1993) Ann. Neurol. , vol.34 , pp. 752
- Mayeux, R.¹ Stern, Y.² Ottman, R.³ Tatemichi, T.K.⁴ Tang, M.⁵ Maestre, G.⁶ Nagai, C.⁷ Tycko, B.⁸ Ginsberg, H.⁹

31
- 0026907151
- A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid
- Mullan, M., F. Crawford, K. Axelman, H. Houlden, L. Lilius, B. Winblad, and L. Lannfelt. 1992a. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid. Nat. Genet, 1: 345.
- (1992) Nat. Genet , vol.1 , pp. 345
- Mullan, M.¹ Crawford, F.² Axelman, K.³ Houlden, H.⁴ Lilius, L.⁵ Winblad, B.⁶ Lannfelt, L.⁷

32
- 0027024651
- A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the al-antichymotrypsin gene
- Mullan, M., H. Houlden, M. Windelspecht, L. Fidani, C. Lombardi, P. Diaz, M. Rossor, R. Crook, J. Hardy, K. Duff, and F. Crawford. 1992b. A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the al-antichymotrypsin gene. Nat. Genet. 2: 340.
- (1992) Nat. Genet. , vol.2 , pp. 340
- Mullan, M.¹ Houlden, H.² Windelspecht, M.³ Fidani, L.⁴ Lombardi, C.⁵ Diaz, P.⁶ Rossor, M.⁷ Crook, R.⁸ Hardy, J.⁹ Duff, K.¹⁰ Crawford, F.¹¹

33
- 0025950987
- A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease
- Murrell, J., M. Farlow, B. Ghetti, and M. Benson. 1991. A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science 254: 97.
- (1991) Science , vol.254 , pp. 97
- Murrell, J.¹ Farlow, M.² Ghetti, B.³ Benson, M.⁴

34
- 0025971426
- Apolipoprotein e immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt Jacob disease
- Namba, Y., M. Tomonaga, H. Kawasaki, E. Otomo, and K. Ikeda. 1989. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt Jacob disease. Brain Res. 541: 163.
- (1989) Brain Res. , vol.541 , pp. 163
- Namba, Y.¹ Tomonaga, M.² Kawasaki, H.³ Otomo, E.⁴ Ikeda, K.⁵

35
- 0025754007
- Mis-sense mutation Val→Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease
- Naruse, S., S. Igarashi, H. Kobayashi, K. Aoki, T. Inuzuka, K. Kaneko, T. Shimizu, K. Iihara, T. Kojima, T. Miyatake, and S. Tsuji. 1991. Mis-sense mutation Val→Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease. Lancet 337: 978.
- (1991) Lancet , vol.337 , pp. 978
- Naruse, S.¹ Igarashi, S.² Kobayashi, H.³ Aoki, K.⁴ Inuzuka, T.⁵ Kaneko, K.⁶ Shimizu, T.⁷ Iihara, K.⁸ Kojima, T.⁹ Miyatake, T.¹⁰ Tsuji, S.¹¹

36
- 0020692622
- A family with histologically confirmed Alzheimer's disease
- Nee, L.E., R.J. Polinsky, R. Eldridge, H. Weingartner, S. Smallberg, and M. Ebert. 1983. A family with histologically confirmed Alzheimer's disease. Arch. Neurol. 40: 203.
- (1983) Arch. Neurol. , vol.40 , pp. 203
- Nee, L.E.¹ Polinsky, R.J.² Eldridge, R.³ Weingartner, H.⁴ Smallberg, S.⁵ Ebert, M.⁶

37
- 0027203749
- Apolipoprotein e genotype and Alzheimer's disease
- Noguchi, S., K. Murakami, and N. Yamada. 1993. Apolipoprotein E genotype and Alzheimer's disease. Lancet 342: 737.
- (1993) Lancet , vol.342 , pp. 737
- Noguchi, S.¹ Murakami, K.² Yamada, N.³

38
- 0029995855
- Presenilin 1 polymorphism and Alzheimer's disease
- Perez-Tur, J., F. Wavrantdevieze, J. Lambert, and M.-C. Chartier-Harlin. 1996. Presenilin 1 polymorphism and Alzheimer's disease. Lancet 347: 1560.
- (1996) Lancet , vol.347 , pp. 1560
- Perez-Tur, J.¹ Wavrantdevieze, F.² Lambert, J.³ Chartier-Harlin, M.-C.⁴

39
- 0029554875
- A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene
- Perez-Tur, J., S. Froelich, G. Prihar, R. Crook, M. Baker, K. Duff, M. Wragg, F. Busfield, C. Lendon, R.F. Clark, P. Roques, R.A. Fuldner, J. Johnston, R. Cowburn, C. Forsell, K. Axelman, L. Lilius, H. Houlden, E. Karran, G.W. Roberts, M. Rossor, M.D. Adams, J. Hardy, A. Goate, L. Lannfelt, and M. Hutton. 1995. A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene. NeuroReport 7: 297.
- (1995) NeuroReport , vol.7 , pp. 297
- Perez-Tur, J.¹ Froelich, S.² Prihar, G.³ Crook, R.⁴ Baker, M.⁵ Duff, K.⁶ Wragg, M.⁷ Busfield, F.⁸ Lendon, C.⁹ Clark, R.F.¹⁰ Roques, P.¹¹ Fuldner, R.A.¹² Johnston, J.¹³ Cowburn, R.¹⁴ Forsell, C.¹⁵ Axelman, K.¹⁶ Lilius, L.¹⁷ Houlden, H.¹⁸ Karran, E.¹⁹ Roberts, G.W.²⁰ more..

40
- 0025735884
- Genetic linkage studies in late onset familial Alzheimer's disease
- Pericak-Vance, M.A., J. Bebout, P. Gaskell, L. Yamaoka, W. Hung, M. Alberts, A. Walker, R. Bartlett, C. Haynes, K. Welsh, and A. Roses. 1991. Genetic linkage studies in late onset familial Alzheimer's disease. Am. J. Hum. Genet. 48: 1034.
- (1991) Am. J. Hum. Genet. , vol.48 , pp. 1034
- Pericak-Vance, M.A.¹ Bebout, J.² Gaskell, P.³ Yamaoka, L.⁴ Hung, W.⁵ Alberts, M.⁶ Walker, A.⁷ Bartlett, R.⁸ Haynes, C.⁹ Welsh, K.¹⁰ Roses, A.¹¹

41
- 0027282035
- Apolipoprotein e polymorphism and Alzheimer's disease
- Poirier, J., J. Davignon, D. Bouthillier, S. Kogan, P. Bertrand, and S. Gauthier. 1993. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 342: 697.
- (1993) Lancet , vol.342 , pp. 697
- Poirier, J.¹ Davignon, J.² Bouthillier, D.³ Kogan, S.⁴ Bertrand, P.⁵ Gauthier, S.⁶

42
- 0027374047
- Apolipoprotein e in sporadic Alzheimer's disease: Allelic variation and receptor interactions
- Rebeck, G.W., J. Reiter, D. Strickland, and B. Hyman. 1993. Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions. Neuron 11: 575.
- (1993) Neuron , vol.11 , pp. 575
- Rebeck, G.W.¹ Reiter, J.² Strickland, D.³ Hyman, B.⁴

43
- 0029101491
- Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Aizheimer's disease type 3 gene
- Rogaev, E.I., R. Sherrington, E. Rogaeva, G. Levesque, M. Ikeda, Y. Liang, H. Chi, C. Lin, K. Holman, T. Tsuda, L. Mar, S. Sorbi, B. Nacmias, S. Placentini, L. Amaducci, I. Chumakov, D. Cohen, L. Lannfelt, P. Fraser, J. Rommens, and P.H. St. George-Hyslop. 1995. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Aizheimer's disease type 3 gene. Nature 376: 775.
- (1995) Nature , vol.376 , pp. 775
- Rogaev, E.I.¹ Sherrington, R.² Rogaeva, E.³ Levesque, G.⁴ Ikeda, M.⁵ Liang, Y.⁶ Chi, H.⁷ Lin, C.⁸ Holman, K.⁹ Tsuda, T.¹⁰ Mar, L.¹¹ Sorbi, S.¹² Nacmias, B.¹³ Placentini, S.¹⁴ Amaducci, L.¹⁵ Chumakov, I.¹⁶ Cohen, D.¹⁷ Lannfelt, L.¹⁸ Fraser, P.¹⁹ Rommens, J.²⁰ St George-Hyslop, P.H.²¹ more..

44
- 0029899593
- Incomplete penetrance of FAD in a pedigree with a novel PS-1 gene mutation
- Rossor, M., N. Fox, J. Beck, T. Campbell, and J. Collinge. 1996. Incomplete penetrance of FAD in a pedigree with a novel PS-1 gene mutation. Lancet 347: 1560.
- (1996) Lancet , vol.347 , pp. 1560
- Rossor, M.¹ Fox, N.² Beck, J.³ Campbell, T.⁴ Collinge, J.⁵

45
- 0030048505
- Identification and characterization of presenilin I-467, I-463 and I-374
- Sahara, N., Y. Yahagi, H. Takagi, T. Kondo, M. Okochi, M. Usami, T. Shirasawa, and H. Mori. 1996. Identification and characterization of presenilin I-467, I-463 and I-374. FEBS Lett. 381: 7.
- (1996) FEBS Lett. , vol.381 , pp. 7
- Sahara, N.¹ Yahagi, Y.² Takagi, H.³ Kondo, T.⁴ Okochi, M.⁵ Usami, M.⁶ Shirasawa, T.⁷ Mori, H.⁸

46
- 0027327267
- Association of apolipoprotein e allele E4 with late-onset familial and sporadic Alzheimer's disease
- Saunders, A.M., W. Strittmatter, D. Schmechel, P. St. George-Hyslop, M. Pericak-Vance, S. Joo, B. Rosi, J. Gusella, D. Crapper-MacLachlan, M. Alberts, C. Hulette, B. Crain, D. Goldgaber, and A. Roses. 1993. Association of apolipoprotein E allele E4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43: 1467.
- (1993) Neurology , vol.43 , pp. 1467
- Saunders, A.M.¹ Strittmatter, W.² Schmechel, D.³ St George-Hyslop, P.⁴ Pericak-Vance, M.⁵ Joo, S.⁶ Rosi, B.⁷ Gusella, J.⁸ Crapper-MacLachlan, D.⁹ Alberts, M.¹⁰ Hulette, C.¹¹ Crain, B.¹² Goldgaber, D.¹³ Roses, A.¹⁴

47
- 0026471656
- Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14
- Schellenberg, G.D., T. Bird, E. Wijsman, H. Orr, L. Anderson, E. Nemens, J. White, L. Bonnycastle, J. Weber, M. Alonso, H. Potter, L. Heston, and G. Martin. 1992. Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. Science 258: 668.
- (1992) Science , vol.258 , pp. 668
- Schellenberg, G.D.¹ Bird, T.² Wijsman, E.³ Orr, H.⁴ Anderson, L.⁵ Nemens, E.⁶ White, J.⁷ Bonnycastle, L.⁸ Weber, J.⁹ Alonso, M.¹⁰ Potter, H.¹¹ Heston, L.¹² Martin, G.¹³

48
- 34547386383
- The extracellular concentration of amyioid β-protein (Aβ) ending at Aβ42(43) is increased in vivo by the presenilin 1/2 and amyloid β-protein precursor mutations linked to familial Alzheimer's disease
- Scheuner, D., C. Eckman, M. Jensen, X. Song, M. Citron, N. Suzuki, T. Bird, J. Hardy, M. Hutton, W. Kukull, L. Lannfelt, E. Larson, E. Levy-Lahad, E. Poskind, P. Poorkaj, G. Schellenberg, R. Tanzi, M. Vihanen, W. Wasco, D. Selkoe, and S. Younkin. 1996. The extracellular concentration of amyioid β-protein (Aβ) ending at Aβ42(43) is increased in vivo by the presenilin 1/2 and amyloid β-protein precursor mutations linked to familial Alzheimer's disease. Nat. Med. 2: 1.
- (1996) Nat. Med. , vol.2 , pp. 1
- Scheuner, D.¹ Eckman, C.² Jensen, M.³ Song, X.⁴ Citron, M.⁵ Suzuki, N.⁶ Bird, T.⁷ Hardy, J.⁸ Hutton, M.⁹ Kukull, W.¹⁰ Lannfelt, L.¹¹ Larson, E.¹² Levy-Lahad, E.¹³ Poskind, E.¹⁴ Poorkaj, P.¹⁵ Schellenberg, G.¹⁶ Tanzi, R.¹⁷ Vihanen, M.¹⁸ Wasco, W.¹⁹ Selkoe, D.²⁰ Younkin, S.²¹ more..

49
- 0029995855
- Presenilin 1 polymorphism and Alzheimer's disease
- Scott, W., J. Growdon, A. Roses, J. Haines, and M. Pericak-Vance. 1996. Presenilin 1 polymorphism and Alzheimer's disease. Lancet 347: 1186.
- (1996) Lancet , vol.347 , pp. 1186
- Scott, W.¹ Growdon, J.² Roses, A.³ Haines, J.⁴ Pericak-Vance, M.⁵

50
- 0029004341
- Cloning of a gene bearing mis-sense mutations in early-onset familial Alzheimer's disease
- Sherrington, R., E. Rogaev, Y. Liang, E. Rogaeva, G. Levesque, M. Ikeda, H. Chi, C. Lin, K. Holman, T. Tsuda, L. Mar, J-F. Foncin, A. Bruni, M. Montesi, S. Sorbi, I. Rainero, L. Pinessi, L. Nee, I. Chumakov, D. Pollen, A. Brookes, P. Sanseau, R. Polinsky, W. Wasco, H. da Silva, J. Haines, M. Pericak-Vance, R. Tanzi, A. Roses, P. Fraser, J. Rommens, and P. St. George-Hyslop. 1995. Cloning of a gene bearing mis-sense mutations in early-onset familial Alzheimer's disease. Nature 375: 754.
- (1995) Nature , vol.375 , pp. 754
- Sherrington, R.¹ Rogaev, E.² Liang, Y.³ Rogaeva, E.⁴ Levesque, G.⁵ Ikeda, M.⁶ Chi, H.⁷ Lin, C.⁸ Holman, K.⁹ Tsuda, T.¹⁰ Mar, L.¹¹ Foncin, J.-F.¹² Bruni, A.¹³ Montesi, M.¹⁴ Sorbi, S.¹⁵ Rainero, I.¹⁶ Pinessi, L.¹⁷ Nee, L.¹⁸ Chumakov, I.¹⁹ Pollen, D.²⁰ more..

51
- 0025373508
- Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing
- Sisodia, S., E. Koo, K. Beyreuther, A. Unterbeck, and D. Price. 1990. Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing. Science 248: 492.
- (1990) Science , vol.248 , pp. 492
- Sisodia, S.¹ Koo, E.² Beyreuther, K.³ Unterbeck, A.⁴ Price, D.⁵

52
- 0027205142
- APP717 and Alzheimer's disease in Italy
- Sorbi, S., B. Nacmias, P. Forleo, S. Piacentini, and L. Amaducci. 1993. APP717 and Alzheimer's disease in Italy. Nat. Genet. 4: 10.
- (1993) Nat. Genet. , vol.4 , pp. 10
- Sorbi, S.¹ Nacmias, B.² Forleo, P.³ Piacentini, S.⁴ Amaducci, L.⁵

53
- 0023103748
- The genetic defect causing familial Alzheimer's disease maps on chromosome 21
- St. George-Hyslop, P.H., R.E. Tanzi, R. Polinsky, J. Haines, L. Nee, P. Watkins, R. Myers, R. Feldman, D. Pollen, D. Drachman, J. Growdon, A. Bruni, J.-F. Foncin, D. Salmon, P. Frommelt, L. Amaducci, S. Sorbi, S. Piacantini, G. Stewart, W. Hobbes, P.M. Conneally, and J. Gusella. 1987. The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science 235: 885.
- (1987) Science , vol.235 , pp. 885
- St George-Hyslop, P.H.¹ Tanzi, R.E.² Polinsky, R.³ Haines, J.⁴ Nee, L.⁵ Watkins, P.⁶ Myers, R.⁷ Feldman, R.⁸ Pollen, D.⁹ Drachman, D.¹⁰ Growdon, J.¹¹ Bruni, A.¹² Foncin, J.-F.¹³ Salmon, D.¹⁴ Frommelt, P.¹⁵ Amaducci, L.¹⁶ Sorbi, S.¹⁷ Piacantini, S.¹⁸ Stewart, G.¹⁹ Hobbes, W.²⁰ Conneally, P.M.²¹ Gusella, J.²² more..

54
- 0027032695
- Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14
- St. George-Hyslop, P., J. Haines, E. Rogaev, M. Mortilla, G. Vaula, M. Pericak-Vance, J.-F. Foncin, M. Montesi, A. Bruni, S. Sorbi, I. Rainero, L. Pinessi, D. Pollen, R. Polinsky, L. Nee, J. Kennedy, F. Macciardi, E. Rogaeva, Y. Liang, N. Alexandrova, W. Lukiw, K. Schlumpf, R. Tanzi, T. Tsuda, L. Farrer, J.-M. Cantu, R. Duara, L. Amaducci, L. Bergamini, J. Gusella, A. Roses, and D. Crapper-McLachlan. 1992. Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. Nat. Genet. 2: 330.
- (1992) Nat. Genet. , vol.2 , pp. 330
- St George-Hyslop, P.¹ Haines, J.² Rogaev, E.³ Mortilla, M.⁴ Vaula, G.⁵ Pericak-Vance, M.⁶ Foncin, J.-F.⁷ Montesi, M.⁸ Bruni, A.⁹ Sorbi, S.¹⁰ Rainero, I.¹¹ Pinessi, L.¹² Pollen, D.¹³ Polinsky, R.¹⁴ Nee, L.¹⁵ Kennedy, J.¹⁶ Macciardi, F.¹⁷ Rogaeva, E.¹⁸ Liang, Y.¹⁹ Alexandrova, N.²⁰ more..

55
- 0027407565
- High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
- Strittmatter, W.J., A. Saunders, D. Schmechel, M. Pericak-Vance, J. Enghild, G. Salvesen, and A. Roses. 1993. High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl Acad. Sci 90: 1977.
- (1993) Proc. Natl Acad. Sci , vol.90 , pp. 1977
- Strittmatter, W.J.¹ Saunders, A.² Schmechel, D.³ Pericak-Vance, M.⁴ Enghild, J.⁵ Salvesen, G.⁶ Roses, A.⁷

56
- 0028322017
- An increased percentage of long amyloid β protein secreted by familial amyloid β protein precursor (βAPP717) mutants
- Suzuki, N., T. Cheung, X-D. Cai, A. Odaka, L. Otvos, C. Eckman, T. Golde, and S. Younkin. 1994. An increased percentage of long amyloid β protein secreted by familial amyloid β protein precursor (βAPP717) mutants. Science 264: 1336.
- (1994) Science , vol.264 , pp. 1336
- Suzuki, N.¹ Cheung, T.² Cai, X.-D.³ Odaka, A.⁴ Otvos, L.⁵ Eckman, C.⁶ Golde, T.⁷ Younkin, S.⁸

57
- 0028278060
- Protection against Alzheimer's disease with apoE epsilon 2
- Talbot, C., C. Lendon, N. Craddock, S. Shears, J.C. Morris, and A. Goate. 1994. Protection against Alzheimer's disease with apoE epsilon 2. Lancet 343: 1432.
- (1994) Lancet , vol.343 , pp. 1432
- Talbot, C.¹ Lendon, C.² Craddock, N.³ Shears, S.⁴ Morris, J.C.⁵ Goate, A.⁶

58
- 0023109592
- Amyloid beta protein gene: CDNA, mRNA distribution, and genetic linkage near the Alzheimer locus
- Tanzi, R.E., J. Gusella, P. Watkins, G. Bruns, P. St. George-Hyslop, M. Van Keuren, D. Patterson, S. Pagan, D. Kurnit, and R. Neve. 1987. Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science 235: 880.
- (1987) Science , vol.235 , pp. 880
- Tanzi, R.E.¹ Gusella, J.² Watkins, P.³ Bruns, G.⁴ St George-Hyslop, P.⁵ Van Keuren, M.⁶ Patterson, D.⁷ Pagan, S.⁸ Kurnit, D.⁹ Neve, R.¹⁰

59
- 0027031612
- Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3
- Van Broeckhoven, C., H. Backhovens, M. Cruts, G. De Winter, M. Bruyland, P. Cras, and J.-J. Martin. 1992. Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3. Nat. Genet. 2: 335.
- (1992) Nat. Genet. , vol.2 , pp. 335
- Van Broeckhoven, C.¹ Backhovens, H.² Cruts, M.³ De Winter, G.⁴ Bruyland, M.⁵ Cras, P.⁶ Martin, J.-J.⁷

60
- 0025768826
- Familial aggregation of Alzheimer's disease and related disorders: A collaborative re-analysis of casecontrol studies
- van Duijn, C.M., D. Clayton, V. Chandra, L. Fratiglioni, A. Graves, A. Heyman, A. Jorm, E. Kokmen, K. Kondo, J. Mortimer, W. Rocca, S. Shalat, H. Soininen, and A. Hofman. 1991. Familial aggregation of Alzheimer's disease and related disorders: A collaborative re-analysis of casecontrol studies. Int. J. Epidemiol. (suppl. 2) 20: S13.
- (1991) Int. J. Epidemiol. (Suppl. 2) , vol.20
- Van Duijn, C.M.¹ Clayton, D.² Chandra, V.³ Fratiglioni, L.⁴ Graves, A.⁵ Heyman, A.⁶ Jorm, A.⁷ Kokmen, E.⁸ Kondo, K.⁹ Mortimer, J.¹⁰ Rocca, W.¹¹ Shalat, S.¹² Soininen, H.¹³ Hofman, A.¹⁴

61
- 0029671219
- 2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3
- 2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science 271: 521.
- (1996) Science , vol.271 , pp. 521
- Vito, P.¹ Lacana, E.² D'Adamio, L.³

62
- 0029052710
- Familial Alzheimer's chromosome 14 mutations
- Wasco, W., W. Pettingell, P. Jondro, S. Schmidt, S. Gurubhagavatula, L. Rodes, T. DiBlasi, D. Romano, S. Guenette, D. Kovacs, J. Growdon, and R. Tanzi. 1995. Familial Alzheimer's chromosome 14 mutations. Nat. Med. 1: 848.
- (1995) Nat. Med. , vol.1 , pp. 848
- Wasco, W.¹ Pettingell, W.² Jondro, P.³ Schmidt, S.⁴ Gurubhagavatula, S.⁵ Rodes, L.⁶ DiBlasi, T.⁷ Romano, D.⁸ Guenette, S.⁹ Kovacs, D.¹⁰ Growdon, J.¹¹ Tanzi, R.¹²

63
- 0028822488
- S182 protein in Alzheimer's disease neuritic plaques
- Wisniewski, T., J. Palha, J. Ghiso, and B. Frangione. 1995. S182 protein in Alzheimer's disease neuritic plaques. Lancer 346: 1366.
- (1995) Lancer , vol.346 , pp. 1366
- Wisniewski, T.¹ Palha, J.² Ghiso, J.³ Frangione, B.⁴

64
- 0030028429
- Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease
- Wragg, M., M. Hutton, C. Talbot, F. Busfield, S.W. Han, C. Lendon, R.F. Clark, J.C. Morris, D. Edwards, E. Pfeiffer, R. Crook, G. Prihar, H. Phillips, M. Baker, M. Rossor, H. Houlden, E. Karran, G. Roberts, N. Craddock, A. Goate, and J. Hardy. 1996. Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease. Lancet 347: 509.
- (1996) Lancet , vol.347 , pp. 509
- Wragg, M.¹ Hutton, M.² Talbot, C.³ Busfield, F.⁴ Han, S.W.⁵ Lendon, C.⁶ Clark, R.F.⁷ Morris, J.C.⁸ Edwards, D.⁹ Pfeiffer, E.¹⁰ Crook, R.¹¹ Prihar, G.¹² Phillips, H.¹³ Baker, M.¹⁴ Rossor, M.¹⁵ Houlden, H.¹⁶ Karran, E.¹⁷ Roberts, G.¹⁸ Craddock, N.¹⁹ Goate, A.²⁰ Hardy, J.²¹ more..

65
- 0025925236
- The 717Val→Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups
- Yoshioka, K, T. Miki, T. Katsuya, T. Ogihara, and Y. Sakaki. 1991. The 717Val→Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups. Biochem. Biophys. Res. Commun. 178: 1141.
- (1991) Biochem. Biophys. Res. Commun. , vol.178 , pp. 1141
- Yoshioka, K.¹ Miki, T.² Katsuya, T.³ Ogihara, T.⁴ Sakaki, Y.⁵

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