Synthesis and screening of small molecule libraries active in binding to DNA

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 22, 1997, Pages 11833-11838

  Shipps Jr , Gerald W ^a,b,d   Pryor, Kent E ^a,b   Xian, Jun ^c   Skyler, David A ^a   Davidson, Eric H ^c   Rebek Jr , Julius ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^d NeoGenesis Pharmaceuticals Inc   (United States)

Author keywords

Combinatorial chemistry; Diversity; DNA binding; Gel shift assay; Ureas

Indexed keywords

TRANSCRIPTION FACTOR; UREA DERIVATIVE;

ARTICLE; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DNA BINDING; SYNTHESIS; TRANSCRIPTION REGULATION;

DNA; DNA-BINDING PROTEINS; INTERCALATING AGENTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; UREA; XANTHENES;

EID: 12644264317     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.22.11833     Document Type: Article

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