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Volumn 2, Issue 4, 1996, Pages 429-451

Endogenous and synthetic cannabinoids: Recent advances

Author keywords

2 Arachidonoyl glycerol; Anandamide; Cannabinoid receptors; Head trauma; HU 210; HU 211 9 Tetrahydrocannabinol

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ANANDAMIDE; ANTIOXIDANT; CANNABINOID; DEXANABINOL; N METHYL DEXTRO ASPARTIC ACID; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG;

EID: 12644253801     PISSN: 1080563X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-3458.1996.tb00310.x     Document Type: Article
Times cited : (16)

References (136)
  • 1
    • 0026055727 scopus 로고
    • A second messenger role for monoacylglycerols is suggested by their activating effects on the sodium pump
    • Askari A, Xie Z, Wang Y, Periyasamy S, Huang WH. A second messenger role for monoacylglycerols is suggested by their activating effects on the sodium pump. Biochim Biophys Acta 1991;1069:127-130.
    • (1991) Biochim Biophys Acta , vol.1069 , pp. 127-130
    • Askari, A.1    Xie, Z.2    Wang, Y.3    Periyasamy, S.4    Huang, W.H.5
  • 2
    • 0028564867 scopus 로고
    • Neuroprotective activity of HU-211: A novel NMDA antagonist, in global ischemia in gerbils
    • Bar-Joseph A, Berkovitch Y, Adamchik J, Biegon A. Neuroprotective activity of HU-211: A novel NMDA antagonist, in global ischemia in gerbils. Mol Chem Neuropathol 1994;23:125-135.
    • (1994) Mol Chem Neuropathol , vol.23 , pp. 125-135
    • Bar-Joseph, A.1    Berkovitch, Y.2    Adamchik, J.3    Biegon, A.4
  • 3
    • 0030041950 scopus 로고    scopus 로고
    • A novel non-psychotropic cannabinoid, HU-211, in the treatment of experimental pneumococcal meningitis
    • Bass R, Trembovler V, Engelhard D, Shohami E. A novel non-psychotropic cannabinoid, HU-211, in the treatment of experimental pneumococcal meningitis. J Inf Dis 1996;173:735-738.
    • (1996) J Inf Dis , vol.173 , pp. 735-738
    • Bass, R.1    Trembovler, V.2    Engelhard, D.3    Shohami, E.4
  • 4
    • 0028789427 scopus 로고
    • The peripheral cannabinoid receptor: Adenylate cyclase inhibition and G protein coupling
    • Bayewitch M, Avidor-Reiss T, Levy R, Barg J, Mechoulam R, Vogel Z. The peripheral cannabinoid receptor: Adenylate cyclase inhibition and G protein coupling. FEBS Lett 1995;375:143-147.
    • (1995) FEBS Lett , vol.375 , pp. 143-147
    • Bayewitch, M.1    Avidor-Reiss, T.2    Levy, R.3    Barg, J.4    Mechoulam, R.5    Vogel, Z.6
  • 5
    • 0029664402 scopus 로고    scopus 로고
    • (-)-Delta(9)-Tetrahydrocannabinol antagonizes the peripheral cannabinoid receptor-mediated inhibition of adenylyl cyclase
    • Bayewitch M, Rhee RH, Avidor-Reiss T, Breuer A, Mechoulam R, Vogel Z. (-)-Delta(9)-Tetrahydrocannabinol antagonizes the peripheral cannabinoid receptor-mediated inhibition of adenylyl cyclase. J Biol Chem 1996;271:9902-9905.
    • (1996) J Biol Chem , vol.271 , pp. 9902-9905
    • Bayewitch, M.1    Rhee, R.H.2    Avidor-Reiss, T.3    Breuer, A.4    Mechoulam, R.5    Vogel, Z.6
  • 6
    • 0029074225 scopus 로고
    • HU-211, a non-psychotropic cannabinoid, improves neurological signs and reduces brain damage, after severe forebrain ischemia in rats
    • Belayev L, Bar-Joseph A, Adamchik J, Biegon A. HU-211, a non-psychotropic cannabinoid, improves neurological signs and reduces brain damage, after severe forebrain ischemia in rats. Mol Chem Neuropathol 1995;25:19-33.
    • (1995) Mol Chem Neuropathol , vol.25 , pp. 19-33
    • Belayev, L.1    Bar-Joseph, A.2    Adamchik, J.3    Biegon, A.4
  • 7
    • 0028973635 scopus 로고
    • Post-ischemic administration of HU-211, a novel noncompetitive NMDA antagonist, protects against blood-brain barrier disruption in photochemical cortical infarction in rats: A quantitative study
    • Belayev L, Busto R, Watson B, Ginsberg MD. Post-ischemic administration of HU-211, a novel noncompetitive NMDA antagonist, protects against blood-brain barrier disruption in photochemical cortical infarction in rats: A quantitative study. Brain Res 1995;702:266-270.
    • (1995) Brain Res , vol.702 , pp. 266-270
    • Belayev, L.1    Busto, R.2    Watson, B.3    Ginsberg, M.D.4
  • 8
    • 0025755870 scopus 로고
    • Antinociceptive (aminoalkyl) indoles
    • Bell MR, D'Ambra TE, Kumar V, et al. Antinociceptive (aminoalkyl) indoles. J Med Chem 1991;34:1099-1110.
    • (1991) J Med Chem , vol.34 , pp. 1099-1110
    • Bell, M.R.1    D'Ambra, T.E.2    Kumar, V.3
  • 9
    • 0021707433 scopus 로고
    • Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • Benveniste H, Drejer J, Schousboe A, Diemer NH. Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 1984;43:1369-1374.
    • (1984) J Neurochem , vol.43 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 11
    • 0021276001 scopus 로고
    • Activation of acute phase responses by intrapreoptic injections of endogenous pyrogen in guinea pigs
    • Blatteis CM, Hunter WS, Llanos QJ, Ahokas RA, Mashburn TA Jr. Activation of acute phase responses by intrapreoptic injections of endogenous pyrogen in guinea pigs. Brain Res Bull 1984;12:689-695.
    • (1984) Brain Res Bull , vol.12 , pp. 689-695
    • Blatteis, C.M.1    Hunter, W.S.2    Llanos, Q.J.3    Ahokas, R.A.4    Mashburn Jr., T.A.5
  • 13
    • 0029889256 scopus 로고    scopus 로고
    • Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP
    • Cadas H, Gaillet S, Beltramo M, Venance L, Piomelli D. Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP. J Neurosci 1996;16:3934-3942.
    • (1996) J Neurosci , vol.16 , pp. 3934-3942
    • Cadas, H.1    Gaillet, S.2    Beltramo, M.3    Venance, L.4    Piomelli, D.5
  • 14
    • 0028938212 scopus 로고
    • Metabolism of cottonseed microsomal N-acylphosphatidylethanolamine
    • Chapman KD, Lin I, DeSouza AD. Metabolism of cottonseed microsomal N-acylphosphatidylethanolamine. Arch Biochem Biophys 1995;2:401-407.
    • (1995) Arch Biochem Biophys , vol.2 , pp. 401-407
    • Chapman, K.D.1    Lin, I.2    DeSouza, A.D.3
  • 15
    • 0028265784 scopus 로고
    • Effects of anandamide on cannabinoid receptors in rat brain membranes
    • Childers SR, Sexton T, Roy MB. Effects of anandamide on cannabinoid receptors in rat brain membranes. Biochem Pharmacol 1994;47:711-715.
    • (1994) Biochem Pharmacol , vol.47 , pp. 711-715
    • Childers, S.R.1    Sexton, T.2    Roy, M.B.3
  • 16
    • 0027309113 scopus 로고
    • NMDA receptors and AMPA/kainate receptors mediate parallel injury in cerebral cortical cultures subjected to oxygen-glucose deprivation
    • Kogure K, Hossmann A, Siesjo BK, eds. Amsterdam: Elsevier
    • Choi DW. NMDA receptors and AMPA/kainate receptors mediate parallel injury in cerebral cortical cultures subjected to oxygen-glucose deprivation, in: Kogure K, Hossmann A, Siesjo BK, eds. Progress in Brain Res. Amsterdam: Elsevier, 1993:137-143.
    • (1993) Progress in Brain Res , pp. 137-143
    • Choi, D.W.1
  • 18
    • 0027501457 scopus 로고
    • Cannabinoid structure activity relationships: Correlation of receptor binding and in vivo activities
    • Compton DR, Rice KC, De Costa BR, et al. Cannabinoid structure activity relationships: correlation of receptor binding and in vivo activities. J Pharm Exp Ther 1992;265:218-226.
    • (1992) J Pharm Exp Ther , vol.265 , pp. 218-226
    • Compton, D.R.1    Rice, K.C.2    De Costa, B.R.3
  • 19
    • 0020057377 scopus 로고
    • Alterations in the level of endogenous hypothalamic prostaglandins induced by delta-9-tetrahydrocannabinol in the rat
    • Coupar IM, Taylor DA. Alterations in the level of endogenous hypothalamic prostaglandins induced by delta-9-tetrahydrocannabinol in the rat. Br J Pharmacol 1982;76: 115-119.
    • (1982) Br J Pharmacol , vol.76 , pp. 115-119
    • Coupar, I.M.1    Taylor, D.A.2
  • 20
    • 0017419887 scopus 로고
    • Pharmacologic control of temperature regulation
    • Cox B, Lomax P. Pharmacologic control of temperature regulation. Ann Rev Pharmacol Toxicol 1977;17:341-353.
    • (1977) Ann Rev Pharmacol Toxicol , vol.17 , pp. 341-353
    • Cox, B.1    Lomax, P.2
  • 22
    • 0018971980 scopus 로고
    • The mechanism of action of Δ-9-tetrahydrocannabinol on body temperature in mice
    • Davies JA, Graham DP. The mechanism of action of Δ-9-tetrahydrocannabinol on body temperature in mice. Psychopharmacology 1980;69:299-305.
    • (1980) Psychopharmacology , vol.69 , pp. 299-305
    • Davies, J.A.1    Graham, D.P.2
  • 23
    • 0028903996 scopus 로고
    • Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization
    • Desarnaud F, Cadas H, Piomelli D. Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. J Biol Chem 1995;270:6030-6035.
    • (1995) J Biol Chem , vol.270 , pp. 6030-6035
    • Desarnaud, F.1    Cadas, H.2    Piomelli, D.3
  • 24
    • 0027180394 scopus 로고
    • Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist
    • Deutsch DG, Chin SA. Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. Biochem Pharmacol 1993;46:791-796.
    • (1993) Biochem Pharmacol , vol.46 , pp. 791-796
    • Deutsch, D.G.1    Chin, S.A.2
  • 26
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • Devane WA, Hanus L, Breuer A, et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 1992;258:1946-1949.
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hanus, L.2    Breuer, A.3
  • 27
    • 0014906101 scopus 로고
    • The effect of 1-trans-delta-9-tetrahydrocannabinol on the hypothalamo-hypophyseal-adrenal axis of rats
    • Dewey WL, Peng TC, Harris LS. The effect of 1-trans-delta-9-tetrahydrocannabinol on the hypothalamo-hypophyseal-adrenal axis of rats. Eur J Pharmacol 1970;12:382-384.
    • (1970) Eur J Pharmacol , vol.12 , pp. 382-384
    • Dewey, W.L.1    Peng, T.C.2    Harris, L.S.3
  • 28
    • 0022509199 scopus 로고
    • Cannabinoid pharmacology
    • Dewey WL. Cannabinoid pharmacology. Pharmacol Rev 1986;38:151-178.
    • (1986) Pharmacol Rev , vol.38 , pp. 151-178
    • Dewey, W.L.1
  • 29
    • 0029031421 scopus 로고
    • Anandamide, an endogenous cannabinomimetic eicosanoid: 'Killing two birds with one stone.'
    • Di Marzo V, Fontana A. Anandamide, an endogenous cannabinomimetic eicosanoid: 'Killing two birds with one stone.' Prostag Leuk Ess Fatty Acids 1995;53:1-11.
    • (1995) Prostag Leuk Ess Fatty Acids , vol.53 , pp. 1-11
    • Di Marzo, V.1    Fontana, A.2
  • 30
    • 0028589390 scopus 로고
    • Formation and inactivation of endogenous cannabinoid anandamide in central neurons
    • Di Marzo V, Fontana A, Cadas H, et al. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature 1994;372:686-691.
    • (1994) Nature , vol.372 , pp. 686-691
    • Di Marzo, V.1    Fontana, A.2    Cadas, H.3
  • 31
  • 32
    • 0027243589 scopus 로고
    • Glutamate receptor transmission and ischemic nerve cell damage: Evidence for involvement of excitotoxic mechanism
    • Kogure K, Hossman KA, Siesjo BK, eds. Amsterdam: Elsevier
    • Diemer NH, Valente E, Bruhn T, Berg M, Jorgensen MB, Johansen FF. Glutamate receptor transmission and ischemic nerve cell damage: Evidence for involvement of excitotoxic mechanism, in: Kogure K, Hossman KA, Siesjo BK, eds. Progress in Brain Res. Amsterdam: Elsevier 1993:105-123.
    • (1993) Progress in Brain Res , pp. 105-123
    • Diemer, N.H.1    Valente, E.2    Bruhn, T.3    Berg, M.4    Jorgensen, M.B.5    Johansen, F.F.6
  • 33
    • 0005937321 scopus 로고
    • Interleukins, tumor necrosis factors (cachectin), and interferons as endogenous pyrogens and mediators of fever
    • Pick E, Landy M, eds. New York: Academic Press
    • Dinarello CA. Interleukins, tumor necrosis factors (cachectin), and interferons as endogenous pyrogens and mediators of fever. In: Pick E, Landy M, eds. Lymphokines. New York: Academic Press, 1987:1-31.
    • (1987) Lymphokines , pp. 1-31
    • Dinarello, C.A.1
  • 34
    • 0029134729 scopus 로고
    • (Aminoalkyl) indoles: Structure activity relationships of novel cannabinoid mimetics
    • Eisenstat MA, Bell MR, D'Ambra TE, et al. (Aminoalkyl) indoles: Structure activity relationships of novel cannabinoid mimetics. J Med Chem 1995;38:3094-3105.
    • (1995) J Med Chem , vol.38 , pp. 3094-3105
    • Eisenstat, M.A.1    Bell, M.R.2    D'Ambra, T.E.3
  • 35
    • 0025223111 scopus 로고
    • Cannabinoids interaction with glucocorticoid receptors in rat hippocampus
    • Eldridge JC, Landfield PW. Cannabinoids interaction with glucocorticoid receptors in rat hippocampus. Brain Res 1990;534:135-141.
    • (1990) Brain Res , vol.534 , pp. 135-141
    • Eldridge, J.C.1    Landfield, P.W.2
  • 36
  • 37
    • 0027788085 scopus 로고
    • HU-211, a non-psychotropic cannabinoid, rescues cortical neurons from excitatory amino acid toxicity in culture
    • Eshhar N, Streim S, Biegon A. HU-211, a non-psychotropic cannabinoid, rescues cortical neurons from excitatory amino acid toxicity in culture. NeuroReport 1993;5:237-240.
    • (1993) NeuroReport , vol.5 , pp. 237-240
    • Eshhar, N.1    Streim, S.2    Biegon, A.3
  • 38
    • 0029165097 scopus 로고
    • Neuroprotective and antioxidant activities of HU-211, a novel NMDA receptor antagonist
    • Eshhar N, Streim S, Kohen R, Tirosh O, Biegon A. Neuroprotective and antioxidant activities of HU-211, a novel NMDA receptor antagonist. Eur J Pharmacol 1995;283:1-3.
    • (1995) Eur J Pharmacol , vol.283 , pp. 1-3
    • Eshhar, N.1    Streim, S.2    Kohen, R.3    Tirosh, O.4    Biegon, A.5
  • 39
    • 0028906566 scopus 로고
    • Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide
    • Facci L, Dal-Toso R, Romanello S, Buriani A, Skaper SD, Leon A. Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. Proc Natl Acad Scu USA 1995,92:3376-3380.
    • (1995) Proc Natl Acad Scu USA , vol.92 , pp. 3376-3380
    • Facci, L.1    Dal-Toso, R.2    Romanello, S.3    Buriani, A.4    Skaper, S.D.5    Leon, A.6
  • 40
    • 0028954055 scopus 로고
    • 3 receptors in rat nodose ganglion neurons
    • 3 receptors in rat nodose ganglion neurons. J Neurophysiol 1995;73:907-910.
    • (1995) J Neurophysiol , vol.73 , pp. 907-910
    • Fan, P.1
  • 41
    • 0024316874 scopus 로고
    • Non-psychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker
    • Feigenbaum JJ, Bergmann F, Richmond SA, et al. Non-psychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker. Proc Natl Acad Sci USA 1989;86:9584-9587.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9584-9587
    • Feigenbaum, J.J.1    Bergmann, F.2    Richmond, S.A.3
  • 42
    • 0027185227 scopus 로고
    • Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction
    • Felder CC, Briley EM, Axelrod J, Simpson JT, Mackie K, Devane WA. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc Natl Acad Sci USA 1993;90:7656-7660.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7656-7660
    • Felder, C.C.1    Briley, E.M.2    Axelrod, J.3    Simpson, J.T.4    Mackie, K.5    Devane, W.A.6
  • 44
    • 0028874888 scopus 로고
    • Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines
    • Fontana A, Di Marzo V, Cadas H, Piomelli D. Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines. Prostag Leuk Ess Fatty Acids 1995;53:301-308.
    • (1995) Prostag Leuk Ess Fatty Acids , vol.53 , pp. 301-308
    • Fontana, A.1    Di Marzo, V.2    Cadas, H.3    Piomelli, D.4
  • 45
    • 0028872268 scopus 로고
    • Low doses of anandamides inhibit pharmacological effects of delta-9-tetra-hydrocannabinol
    • Fride E, Barg J, Levy R, et al. Low doses of anandamides inhibit pharmacological effects of delta-9-tetra-hydrocannabinol. J Pharmacol Exp Ther 1995;272:699-707.
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 699-707
    • Fride, E.1    Barg, J.2    Levy, R.3
  • 46
    • 0029890308 scopus 로고    scopus 로고
    • Developmental aspects of anandamide: Ontogeny of response and effects of prenatal exposure to anandamide
    • Fride E, Mechoulam R. Developmental aspects of anandamide: Ontogeny of response and effects of prenatal exposure to anandamide. Psychoneuroendocrinology 1996;21:157-172.
    • (1996) Psychoneuroendocrinology , vol.21 , pp. 157-172
    • Fride, E.1    Mechoulam, R.2
  • 47
    • 0027467421 scopus 로고
    • Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent
    • Fride E, Mechoulam R. Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent. Eur J Pharmacol 1993;231:313-314.
    • (1993) Eur J Pharmacol , vol.231 , pp. 313-314
    • Fride, E.1    Mechoulam, R.2
  • 48
    • 0028783482 scopus 로고
    • Anandamides: Tolerance and cross-tolerance to delta(9)-tetrahydrocannabinol
    • Fride E. Anandamides: Tolerance and cross-tolerance to delta(9)-tetrahydrocannabinol. Brain Res 1995;697:83-90.
    • (1995) Brain Res , vol.697 , pp. 83-90
    • Fride, E.1
  • 49
    • 33947489961 scopus 로고
    • Isolation, structure and partial synthesis of an active constituent of hashish
    • Gaoni Y, Mechoulam R. Isolation, structure and partial synthesis of an active constituent of hashish. J Am Chem Soc 1964;86:1646-1647.
    • (1964) J Am Chem Soc , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 50
    • 0025878961 scopus 로고
    • Molecular cloning of a human cannabinoid receptor which is also expressed in testis
    • Gerard CM, Mollereau C, Vassart G, Parmentier M. Molecular cloning of a human cannabinoid receptor which is also expressed in testis. Biochem J 1991;279:129-134.
    • (1991) Biochem J , vol.279 , pp. 129-134
    • Gerard, C.M.1    Mollereau, C.2    Vassart, G.3    Parmentier, M.4
  • 52
    • 0023941585 scopus 로고
    • MK-801 is neuroprotective in gerbils when administered in the postischemic period
    • Gill R, Foster AC, Woodruff GN. MK-801 is neuroprotective in gerbils when administered in the postischemic period. Neuroscience 1988;25:847-855.
    • (1988) Neuroscience , vol.25 , pp. 847-855
    • Gill, R.1    Foster, A.C.2    Woodruff, G.N.3
  • 53
    • 0023425239 scopus 로고
    • Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in gerbil
    • Gill R, Foster AC, Woodruff GN. Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in gerbil. J Neurosci 1987;7:3329-3343.
    • (1987) J Neurosci , vol.7 , pp. 3329-3343
    • Gill, R.1    Foster, A.C.2    Woodruff, G.N.3
  • 54
    • 0027489995 scopus 로고
    • Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor
    • Hanus L, Gopher A, Almog S, Mechoulam R. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J Med Chem 1993;36:3032-3034.
    • (1993) J Med Chem , vol.36 , pp. 3032-3034
    • Hanus, L.1    Gopher, A.2    Almog, S.3    Mechoulam, R.4
  • 55
    • 0014693484 scopus 로고
    • Delta-9-tetrahydrocannabinol, neurochemical and behavioral effects in the mouse
    • Holtzman D, Lovell RA, Jaffe JH, Freedman DX. Delta-9-tetrahydrocannabinol, neurochemical and behavioral effects in the mouse. Science 1969;163:1464-1467.
    • (1969) Science , vol.163 , pp. 1464-1467
    • Holtzman, D.1    Lovell, R.A.2    Jaffe, J.H.3    Freedman, D.X.4
  • 56
    • 0025186592 scopus 로고
    • Stereochemical effects of 11-OH-delta-8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor
    • Howlett AC, Champion TM, Wilken GH, Mechoulam R. Stereochemical effects of 11-OH-delta-8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor. Neuropharmacology 1990;29:161-165.
    • (1990) Neuropharmacology , vol.29 , pp. 161-165
    • Howlett, A.C.1    Champion, T.M.2    Wilken, G.H.3    Mechoulam, R.4
  • 57
    • 0028987880 scopus 로고
    • Pharmacology of cannabinoid receptors
    • Howlett AC. Pharmacology of cannabinoid receptors. Ann Rev Pharmacol Toxicol 1995;35:607-634.
    • (1995) Ann Rev Pharmacol Toxicol , vol.35 , pp. 607-634
    • Howlett, A.C.1
  • 58
    • 0021966402 scopus 로고
    • Cannabinoid inhibition of adenylate cyclase, biochemistry of the response in neuroblastoma cell membranes
    • Howlett AC. Cannabinoid inhibition of adenylate cyclase, biochemistry of the response in neuroblastoma cell membranes. Mol Pharmacol 1985;27:429-436.
    • (1985) Mol Pharmacol , vol.27 , pp. 429-436
    • Howlett, A.C.1
  • 59
    • 0018776979 scopus 로고
    • The effects of delta-9-tetrahydrocannabinol, cannabidiol, and shock on plasma corticosterone in rats
    • Jacobs JA, Dellarco AJ, Manfredi RA, Harclerode J. The effects of delta-9-tetrahydrocannabinol, cannabidiol, and shock on plasma corticosterone in rats. J Pharm Pharmacol 1979;31:341-342.
    • (1979) J Pharm Pharmacol , vol.31 , pp. 341-342
    • Jacobs, J.A.1    Dellarco, A.J.2    Manfredi, R.A.3    Harclerode, J.4
  • 60
    • 0024441853 scopus 로고
    • Stereospecificity of the discriminative stimulus functions of the dimethylheptyl homologs of 11-OH-delta-8-tetrahydrocannabinol in rats and pigeons
    • Jarbe TUC, Hiltunen AJ, Mechoulam R. Stereospecificity of the discriminative stimulus functions of the dimethylheptyl homologs of 11-OH-delta-8-tetrahydrocannabinol in rats and pigeons. J Pharmacol Exp Ther 1989;250:1000-1005.
    • (1989) J Pharmacol Exp Ther , vol.250 , pp. 1000-1005
    • Jarbe, T.U.C.1    Hiltunen, A.J.2    Mechoulam, R.3
  • 61
    • 0003229120 scopus 로고    scopus 로고
    • Hydroxypropyl-beta-cyclodextrin increases aqueous solubility and stability of anandamide
    • Jarho P, Uritti A, Jarvinen K, Pate DW, Jarvinen T. Hydroxypropyl-beta-cyclodextrin increases aqueous solubility and stability of anandamide. Life Sci 1996;58:181-185.
    • (1996) Life Sci , vol.58 , pp. 181-185
    • Jarho, P.1    Uritti, A.2    Jarvinen, K.3    Pate, D.W.4    Jarvinen, T.5
  • 62
    • 0027221632 scopus 로고
    • Isolation, identification, and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist 1,4-dihydropyridine binding
    • Johnson DE, Heald SL, Daily RD, Janis RA. Isolation, identification, and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist 1,4-dihydropyridine binding. Prostag Lenk Ess Fatty Acids 1993;48:429-437.
    • (1993) Prostag Lenk Ess Fatty Acids , vol.48 , pp. 429-437
    • Johnson, D.E.1    Heald, S.L.2    Daily, R.D.3    Janis, R.A.4
  • 63
    • 0001535921 scopus 로고
    • The discovery of nonclasical cannabinoid analgetics
    • Mechoulam R, ed. Boca Raton: CRC Press
    • Johnson MR, Melvin LS. The discovery of nonclasical cannabinoid analgetics. in:. Mechoulam R, ed. Cannabinoids as Therapeutic Agents. Boca Raton: CRC Press 1986:121-145.
    • (1986) Cannabinoids as Therapeutic Agents , pp. 121-145
    • Johnson, M.R.1    Melvin, L.S.2
  • 64
    • 0014988355 scopus 로고
    • Corticosterone elevation mediated centrally by delta-1-tetrahydrocannabinol in rats
    • Kubena RK, Peehack JC, Barry H. Corticosterone elevation mediated centrally by delta-1-tetrahydrocannabinol in rats. Eur J Pharmacol 1971;14:89-92.
    • (1971) Eur J Pharmacol , vol.14 , pp. 89-92
    • Kubena, R.K.1    Peehack, J.C.2    Barry, H.3
  • 65
    • 0029561788 scopus 로고
    • Effects of putative cannabinoid receptor ligands, anandamide, and 2-arachidonoyl-glycerol on immune function in B6C3F1 mouse splenocytes
    • Lee M, Yang KU, Kaminski NE. Effects of putative cannabinoid receptor ligands, anandamide, and 2-arachidonoyl-glycerol on immune function in B6C3F1 mouse splenocytes. J Pharmacol Exp Ther 1995;275:529-536.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 529-536
    • Lee, M.1    Yang, K.U.2    Kaminski, N.E.3
  • 66
    • 0029044095 scopus 로고
    • Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats
    • Lichtman AH, Dimen KR, Martin BR. Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats. Psychopharmacology 1995;119:282-290.
    • (1995) Psychopharmacology , vol.119 , pp. 282-290
    • Lichtman, A.H.1    Dimen, K.R.2    Martin, B.R.3
  • 67
  • 69
    • 0027300760 scopus 로고
    • Delayed therapy of experimental ischemia with competitive N-methyl-d-aspartate antagonists in rabbits
    • Madden KP, Clark WM, Zivin JA. Delayed therapy of experimental ischemia with competitive N-methyl-d-aspartate antagonists in rabbits. Stroke 1993;24:1068-1071.
    • (1993) Stroke , vol.24 , pp. 1068-1071
    • Madden, K.P.1    Clark, W.M.2    Zivin, J.A.3
  • 70
    • 0016252190 scopus 로고
    • Effect of tetrahydrocannabinols on biosynthesis and utilization of catecholamines in the rat brain
    • Maitre L, Waldmeir PC, Baumann PA. Effect of tetrahydrocannabinols on biosynthesis and utilization of catecholamines in the rat brain. Biochem Pharmacol Suppl 1974;2:845-850.
    • (1974) Biochem Pharmacol Suppl , vol.2 , pp. 845-850
    • Maitre, L.1    Waldmeir, P.C.2    Baumann, P.A.3
  • 71
    • 0029997920 scopus 로고    scopus 로고
    • The endogenous cannabinoid receptor agonist anandamide impairs memory in rats
    • Mallet PE, Beninger RJ. The endogenous cannabinoid receptor agonist anandamide impairs memory in rats. Behav Pharmacol 1996;7:276-284.
    • (1996) Behav Pharmacol , vol.7 , pp. 276-284
    • Mallet, P.E.1    Beninger, R.J.2
  • 72
    • 0029863040 scopus 로고    scopus 로고
    • Modulation of GABAergic transmission in the globus pallidus by the synthetic cannabinoid WIN 55,212-2
    • Maneuf YP, Corssman AR, Brotchie JM. Modulation of GABAergic transmission in the globus pallidus by the synthetic cannabinoid WIN 55,212-2. Synapse 1996;22:382-385.
    • (1996) Synapse , vol.22 , pp. 382-385
    • Maneuf, Y.P.1    Corssman, A.R.2    Brotchie, J.M.3
  • 73
    • 0002866945 scopus 로고
    • Structural requirements for cannabinoid receptor probes
    • Pertwee R, ed. London: Academic Press
    • Martin BR, Thomas BF, Razdan RK. Structural requirements for cannabinoid receptor probes, in: Pertwee R, ed. Cannabinoid Receptors. London: Academic Press, 1995:35-79.
    • (1995) Cannabinoid Receptors , pp. 35-79
    • Martin, B.R.1    Thomas, B.F.2    Razdan, R.K.3
  • 74
    • 0022448676 scopus 로고
    • Cellular effects of cannabinoids
    • Martin BR. Cellular effects of cannabinoids. Pharmacol Rev 1986;38:45-74.
    • (1986) Pharmacol Rev , vol.38 , pp. 45-74
    • Martin, B.R.1
  • 75
    • 0002138596 scopus 로고
    • Molecular biology of the cannabinoid receptor
    • Pertwee R, ed. London: Academic Press
    • Matsuda LA, Bonner TI. Molecular biology of the cannabinoid receptor. in: Pertwee R, ed. Cannabinoid Receptors. London: Academic Press, 1995:117-140.
    • (1995) Cannabinoid Receptors , pp. 117-140
    • Matsuda, L.A.1    Bonner, T.I.2
  • 76
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 1990;346:561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 77
    • 0027449370 scopus 로고
    • Developmental expression of cannabinoid receptor mRNA
    • McLaughlin CR, Abood ME. Developmental expression of cannabinoid receptor mRNA. Dev Brain Res 1993;76:75-78.
    • (1993) Dev Brain Res , vol.76 , pp. 75-78
    • McLaughlin, C.R.1    Abood, M.E.2
  • 78
    • 0029012014 scopus 로고
    • Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
    • Mechoulam R, Ben-Shabat S, Hanus L, et al. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 1995;50:83-90.
    • (1995) Biochem Pharmacol , vol.50 , pp. 83-90
    • Mechoulam, R.1    Ben-Shabat, S.2    Hanus, L.3
  • 79
    • 0014208456 scopus 로고
    • A stereospecific synthesis of (-)delta-1- and (-)delta-6-tetrahydrocannabinols
    • Mechoulam R, Braun P, Gaoni Y. A stereospecific synthesis of (-)delta-1- and (-)delta-6-tetrahydrocannabinols. J Am Chem Soc 1967;89:4552-4554.
    • (1967) J Am Chem Soc , vol.89 , pp. 4552-4554
    • Mechoulam, R.1    Braun, P.2    Gaoni, Y.3
  • 81
    • 0023791260 scopus 로고
    • Enantiomeric cannabinoids: Stereospecificity of psychotropic activity
    • Mechoulam R, Feigenbaum JJ, Lander N, et al. Enantiomeric cannabinoids: Stereospecificity of psychotropic activity. Experientia 1988;44:762-764.
    • (1988) Experientia , vol.44 , pp. 762-764
    • Mechoulam, R.1    Feigenbaum, J.J.2    Lander, N.3
  • 82
    • 0002828258 scopus 로고
    • The unpaved road to the endogenous brain cannabinoid ligands, the anandamides
    • Pertwee R, ed. London: Academic Press
    • Mechoulam R, Fride E. The unpaved road to the endogenous brain cannabinoid ligands, the anandamides. in: Pertwee R, ed. Cannabinoid Receptors. London: Academic Press, 1995:233-258.
    • (1995) Cannabinoid Receptors , pp. 233-258
    • Mechoulam, R.1    Fride, E.2
  • 83
    • 0028032515 scopus 로고
    • The search for endogenous ligands of the cannabinoid receptor
    • Mechoulam R, Hanus L, Martin BR. The search for endogenous ligands of the cannabinoid receptor. Biochem Pharmacol 1994;48:1537-1544.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1537-1544
    • Mechoulam, R.1    Hanus, L.2    Martin, B.R.3
  • 84
    • 0024986448 scopus 로고
    • Synthesis of the individual, pharmacologically distinct, enantiomers of a tetrahydrocannabinol derivative
    • Mechoulam R, Lander N, Breuer A, Zahalka J. Synthesis of the individual, pharmacologically distinct, enantiomers of a tetrahydrocannabinol derivative. Tetrahedron 1990;1:315-319.
    • (1990) Tetrahedron , vol.1 , pp. 315-319
    • Mechoulam, R.1    Lander, N.2    Breuer, A.3    Zahalka, J.4
  • 85
    • 0001978419 scopus 로고
    • The pharmacohistory of Cannabis sativa
    • Mcchoulam R, ed. Boca Raton: CRC Press
    • Mcchoulam R. The pharmacohistory of Cannabis sativa. in: Mcchoulam R, ed. Cannabinoids as Therapeutic Agents. Boca Raton: CRC Press, 1986:1-20.
    • (1986) Cannabinoids as Therapeutic Agents , pp. 1-20
    • Mcchoulam, R.1
  • 86
    • 0344961529 scopus 로고
    • Strategies for cerebroprotection: Post-synaptic glutamate antagonism versus inhibition of ischemia induced glutamate release
    • Krieglstein J, Oberpichler-Schwenk H, eds. Stuttgart: Wissenschaftliche Verlagsgesellschaft
    • Meldrum BS, Moncada C, Lekieffre D, Arvin B, Smith S. Strategies for cerebroprotection: Post-synaptic glutamate antagonism versus inhibition of ischemia induced glutamate release. In: Krieglstein J, Oberpichler-Schwenk H, eds. Pharmacology of Cerebral Ischemia. Stuttgart: Wissenschaftliche Verlagsgesellschaft, 1992:115-119.
    • (1992) Pharmacology of Cerebral Ischemia , pp. 115-119
    • Meldrum, B.S.1    Moncada, C.2    Lekieffre, D.3    Arvin, B.4    Smith, S.5
  • 87
    • 0025390880 scopus 로고
    • Protection against neuronal damage by drugs acting on excitatory neurotransmission
    • Meldrum BS. Protection against neuronal damage by drugs acting on excitatory neurotransmission. Cerebrovasc Brain Metab Rev 1990;2:27-57.
    • (1990) Cerebrovasc Brain Metab Rev , vol.2 , pp. 27-57
    • Meldrum, B.S.1
  • 88
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S, Thomas KL, Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993;365:61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 89
    • 0028981424 scopus 로고
    • 45Ca] accumulation in rat brain alter closed head injury; attenuation by the novel neuroprotective agent HU-211
    • 45Ca] accumulation in rat brain alter closed head injury; attenuation by the novel neuroprotective agent HU-211. Brain Res 1995;685:1-11.
    • (1995) Brain Res , vol.685 , pp. 1-11
    • Nadler, V.1    Biegon, A.2    Beit-Yannai, E.3    Adamchik, J.4    Shohami, E.5
  • 90
    • 0027329873 scopus 로고
    • 45Ca] influx through the N-methyl-D-aspartate receptor ion channel by the non-psychoactive cannabinoid HU-211
    • 45Ca] influx through the N-methyl-D-aspartate receptor ion channel by the non-psychoactive cannabinoid HU-211. Brain Res 1993;622:79-85.
    • (1993) Brain Res , vol.622 , pp. 79-85
    • Nadler, V.1    Mechoulam, R.2    Sokolovsky, M.3
  • 91
    • 0027381303 scopus 로고
    • The non-psychotropic-cannabinoid (+)-(3S,4S)-7-hydroxy-delta-6-tetrahydrocannabinol 1,1-dimethylheptyl (HU-211) attenuates N-methyl-D-aspartate receptor-mediated neurotoxicity in primary cultures of rat forebrain
    • Nadler V, Mechoulam R, Sokolovsky M. The non-psychotropic-cannabinoid (+)-(3S,4S)-7-hydroxy-delta-6-tetrahydrocannabinol 1,1-dimethylheptyl (HU-211) attenuates N-methyl-D-aspartate receptor-mediated neurotoxicity in primary cultures of rat forebrain. Neurosci Lett 1993;162:43-45.
    • (1993) Neurosci Lett , vol.162 , pp. 43-45
    • Nadler, V.1    Mechoulam, R.2    Sokolovsky, M.3
  • 92
    • 0001933595 scopus 로고
    • Neurotoxicity of excitatory amino acids
    • McGeer EG, Olney JW, McGeer PL, eds. New York: Raven Press
    • Olney JW. Neurotoxicity of excitatory amino acids. In: McGeer EG, Olney JW, McGeer PL, eds. Kainic Acid as a Tool in Neurobiology. New York: Raven Press, 1978:37-70.
    • (1978) Kainic Acid as a Tool in Neurobiology , pp. 37-70
    • Olney, J.W.1
  • 93
    • 0028915458 scopus 로고
    • Characterization of the hypothermic effect of the synthetic cannabinoid HU-210 in the rat
    • Ovadia H, Wohlman A, Mechoulam R, Weidenfeld J. Characterization of the hypothermic effect of the synthetic cannabinoid HU-210 in the rat. Neuropharmacology 1995;34:175-180.
    • (1995) Neuropharmacology , vol.34 , pp. 175-180
    • Ovadia, H.1    Wohlman, A.2    Mechoulam, R.3    Weidenfeld, J.4
  • 94
    • 0344071659 scopus 로고
    • The involvement of the central adrenergic system in mediation of interleukin-1 induced fever
    • Bartfai T, Ottoson D, eds. Oxford: Pergamon Press
    • Ovadia H, Weidenfeld J. The involvement of the central adrenergic system in mediation of interleukin-1 induced fever, in: Bartfai T, Ottoson D, eds. Neuroimmunology of Fever. Oxford: Pergamon Press, 1992:37-44.
    • (1992) Neuroimmunology of Fever , pp. 37-44
    • Ovadia, H.1    Weidenfeld, J.2
  • 95
    • 0029133967 scopus 로고
    • Ophthalmic arachidonoylethanolamide decreases intraocular pressure in normotensive rabbits
    • Pate DW, Jarvinen K, Urtti A, Jarho P, Jarvinen T. Ophthalmic arachidonoylethanolamide decreases intraocular pressure in normotensive rabbits. Current Eye Res 1995;14:791-797.
    • (1995) Current Eye Res , vol.14 , pp. 791-797
    • Pate, D.W.1    Jarvinen, K.2    Urtti, A.3    Jarho, P.4    Jarvinen, T.5
  • 96
    • 0027442538 scopus 로고
    • Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2, and anandamide
    • Pertwee RG, Stevenson LA, Griffin G. Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2, and anandamide. Br J Pharmacol 1993;110:1483-1490.
    • (1993) Br J Pharmacol , vol.110 , pp. 1483-1490
    • Pertwee, R.G.1    Stevenson, L.A.2    Griffin, G.3
  • 97
    • 0011930239 scopus 로고
    • Effects of cannabinoids on thermoregulation: A brief review
    • Harvey DJ, Paton W, Nahas GG, eds. Oxford: IRL Press
    • Pertwee RG. Effects of cannabinoids on thermoregulation: A brief review. In: Harvey DJ, Paton W, Nahas GG, eds. Marihuana'84. Proceedings of the Oxford Symposium on Cannabis. Oxford: IRL Press, 1985;263-277.
    • (1985) Marihuana'84. Proceedings of the Oxford Symposium on Cannabis , pp. 263-277
    • Pertwee, R.G.1
  • 99
    • 0023840294 scopus 로고
    • The central neuropharmacology of psychotropic cannabinoids
    • Pertwee RG. The central neuropharmacology of psychotropic cannabinoids. Pharmacol Ther 1988;36:189-261.
    • (1988) Pharmacol Ther , vol.36 , pp. 189-261
    • Pertwee, R.G.1
  • 100
    • 0019945908 scopus 로고
    • Corticotrophin and corticosterone secretion following delta-9-tetrahydrocannabinol in intact and hypothalamic deafferentated male rats
    • Puder M, Weidenfeld J, Chowers I, Nir I, Conforti N, Siegel RA. Corticotrophin and corticosterone secretion following delta-9-tetrahydrocannabinol in intact and hypothalamic deafferentated male rats. Exp Brain Res 1982;46:85.
    • (1982) Exp Brain Res , vol.46 , pp. 85
    • Puder, M.1    Weidenfeld, J.2    Chowers, I.3    Nir, I.4    Conforti, N.5    Siegel, R.A.6
  • 101
    • 0027152254 scopus 로고
    • Antagonism of the NMDA and non-NMDA receptors in global versus focal brain ischemia
    • Kogure K, Hossman K-A, Siesjo BK, eds. Amsterdam: Elsevier
    • Pulsinelli W, Sarokin A, Buchan A. Antagonism of the NMDA and non-NMDA receptors in global versus focal brain ischemia. In: Kogure K, Hossman K-A, Siesjo BK, eds. Progress in Brain Research. Amsterdam: Elsevier, 1993:125-135.
    • (1993) Progress in Brain Research , pp. 125-135
    • Pulsinelli, W.1    Sarokin, A.2    Buchan, A.3
  • 102
    • 85050042248 scopus 로고
    • The total synthesis of cannabinoids
    • J. A. Simon, ed. New York: Wiley
    • Razdan RK. The total synthesis of cannabinoids. In: J. A. Simon, ed. The Total Synthesis of Natural Products. New York: Wiley, 1981;185-262.
    • (1981) The Total Synthesis of Natural Products , pp. 185-262
    • Razdan, R.K.1
  • 104
    • 0029011541 scopus 로고
    • The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: Role of nigrostriatal dopaminergic neurons
    • Romero J, Garcia L, Cebeira M, Zadrozny D, Fernandez-Ruiz JJ, Ramos JA. The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: Role of nigrostriatal dopaminergic neurons. Life Sci 1995;56:2033-2040.
    • (1995) Life Sci , vol.56 , pp. 2033-2040
    • Romero, J.1    Garcia, L.2    Cebeira, M.3    Zadrozny, D.4    Fernandez-Ruiz, J.J.5    Ramos, J.A.6
  • 105
    • 0029043840 scopus 로고
    • Changes in rat brain cannabinoid binding sites after acute or chronic exposure to their endogenous agonist, anandamide or to delta-9-tetrahydrocannabinol
    • Romero J, Garcia L, Fernandez-Ruiz JJ, Cebeira M, Ramos JA. Changes in rat brain cannabinoid binding sites after acute or chronic exposure to their endogenous agonist, anandamide or to delta-9-tetrahydrocannabinol. Pharmacol Biochem Behav 1995;51:731-737.
    • (1995) Pharmacol Biochem Behav , vol.51 , pp. 731-737
    • Romero, J.1    Garcia, L.2    Fernandez-Ruiz, J.J.3    Cebeira, M.4    Ramos, J.A.5
  • 106
    • 0029931386 scopus 로고    scopus 로고
    • Involvement of GABA(B) receptors in the motor inhibition produced by agonists of brain cannabinoid receptors
    • Romero J, Garcia-Palomero E, Fernandez-Ruiz JJ, Ramos JA. Involvement of GABA(B) receptors in the motor inhibition produced by agonists of brain cannabinoid receptors. Behav Pharmacol 1996;7:299-302.
    • (1996) Behav Pharmacol , vol.7 , pp. 299-302
    • Romero, J.1    Garcia-Palomero, E.2    Fernandez-Ruiz, J.J.3    Ramos, J.A.4
  • 107
    • 0014991030 scopus 로고
    • Effect of delta-9-tetrahydrocannabinol on the metabolism of norcpinephrine in rat brain
    • Schildkraut JJ, Efron DH. Effect of delta-9-tetrahydrocannabinol on the metabolism of norcpinephrine in rat brain. Psychopharmacologia 1971;20:191-196.
    • (1971) Psychopharmacologia , vol.20 , pp. 191-196
    • Schildkraut, J.J.1    Efron, D.H.2
  • 108
    • 0025676296 scopus 로고
    • N-acylated glycero-phospholipids and their derivatives
    • Schmid HH, Schmid PC, Natarajan V. N-acylated glycero-phospholipids and their derivatives. Prog Lipid Res 1990;29:1-43.
    • (1990) Prog Lipid Res , vol.29 , pp. 1-43
    • Schmid, H.H.1    Schmid, P.C.2    Natarajan, V.3
  • 109
    • 0028837562 scopus 로고
    • Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain
    • Schmid PC, Krebsbach RJ, Perry SR, Dettmer TM, Maasson JL, Schmid HHO. Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain. FEBS Lettt 1995;375: 117-120.
    • (1995) FEBS Lettt , vol.375 , pp. 117-120
    • Schmid, P.C.1    Krebsbach, R.J.2    Perry, S.R.3    Dettmer, T.M.4    Maasson, J.L.5    Schmid, H.H.O.6
  • 110
    • 0027982533 scopus 로고
    • Anandamide (arachidonoylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction
    • Schuel H, Goldstein E, Mechoulani R, Zimmerman AM, Zimmerman S. Anandamide (arachidonoylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. Proc Natl Acad Sci USA 1994;91:7678-7682.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7678-7682
    • Schuel, H.1    Goldstein, E.2    Mechoulani, R.3    Zimmerman, A.M.4    Zimmerman, S.5
  • 111
    • 0027999501 scopus 로고
    • Anandamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis
    • Schwarz H, Blanco FJ, Lotz M. Anandamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. J Neuroimmunol 1994;55:107-115.
    • (1994) J Neuroimmunol , vol.55 , pp. 107-115
    • Schwarz, H.1    Blanco, F.J.2    Lotz, M.3
  • 112
    • 0023930960 scopus 로고
    • Experimental closed head injury in rats: Mechanical, pathophysiologic and neurologic properties
    • Shapira Y, Shohami E, Sidi A, Soffer D, Freeman S, Cotev S. Experimental closed head injury in rats: Mechanical, pathophysiologic and neurologic properties. Critical Care Med 1988;16:258-265.
    • (1988) Critical Care Med , vol.16 , pp. 258-265
    • Shapira, Y.1    Shohami, E.2    Sidi, A.3    Soffer, D.4    Freeman, S.5    Cotev, S.6
  • 113
    • 0026755481 scopus 로고
    • Methyl-prednisolone does not decrease eicosanoid levels or edema in brain tissue or improve neurological outcome following head trauma in rats
    • Shapira Y, Artru A, Yadid G, Shohami E. Methyl-prednisolone does not decrease eicosanoid levels or edema in brain tissue or improve neurological outcome following head trauma in rats. J Anesth Analg 1992;75:238-244.
    • (1992) J Anesth Analg , vol.75 , pp. 238-244
    • Shapira, Y.1    Artru, A.2    Yadid, G.3    Shohami, E.4
  • 117
    • 0027176336 scopus 로고
    • Interleukin-1 augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus
    • Shintani F, Kanba S, Nakaki T, et al. Interleukin-1 augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus. J Neurosci 1993;13:3574-3581.
    • (1993) J Neurosci , vol.13 , pp. 3574-3581
    • Shintani, F.1    Kanba, S.2    Nakaki, T.3
  • 118
    • 0006701212 scopus 로고    scopus 로고
    • Cytokine production in the brain following closed head injury: TNF-α inhibition is associated with cerebroprotection
    • Shohami E, Bass R, Ben Hur T, Gallily R. Cytokine production in the brain following closed head injury: TNF-α inhibition is associated with cerebroprotection. Eur Cytokine Netw 1996;7:309.
    • (1996) Eur Cytokine Netw , vol.7 , pp. 309
    • Shohami, E.1    Bass, R.2    Ben Hur, T.3    Gallily, R.4
  • 119
    • 0028920429 scopus 로고
    • Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat
    • Shohami E, Novikov M, Bass R. Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat. Brain Res 1995;674:55-62.
    • (1995) Brain Res , vol.674 , pp. 55-62
    • Shohami, E.1    Novikov, M.2    Bass, R.3
  • 120
    • 0027250138 scopus 로고
    • A non-psychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury
    • Shohami E, Novikov M, Mechoulam R. A non-psychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury. J Neurotrauma 1993;10:109-119.
    • (1993) J Neurotrauma , vol.10 , pp. 109-119
    • Shohami, E.1    Novikov, M.2    Mechoulam, R.3
  • 121
    • 0029128197 scopus 로고
    • Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase
    • Slipetz DM, O'Neill GP, Favreau L, et al. Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase. Mol Pharmacol 1995;48:352-361.
    • (1995) Mol Pharmacol , vol.48 , pp. 352-361
    • Slipetz, D.M.1    O'Neill, G.P.2    Favreau, L.3
  • 124
    • 0028970517 scopus 로고
    • 2-Arachidonoyl-glycerol: A possible endogenous cannabinoid receptor ligand in brain
    • Sugiura T, Kondo S, Sukagawa A, et al. 2-Arachidonoyl-glycerol: A possible endogenous cannabinoid receptor ligand in brain. Biochem Biophys Res Comm 1995;215:89-97.
    • (1995) Biochem Biophys Res Comm , vol.215 , pp. 89-97
    • Sugiura, T.1    Kondo, S.2    Sukagawa, A.3
  • 127
    • 0029055851 scopus 로고
    • Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide
    • Varga K, Lake K, Martin BR, Kunos G. Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. Eur J Pharmacol 1995;278:279-283.
    • (1995) Eur J Pharmacol , vol.278 , pp. 279-283
    • Varga, K.1    Lake, K.2    Martin, B.R.3    Kunos, G.4
  • 128
    • 0029154145 scopus 로고
    • Inhibition by anandamide of gap junctions and intercellular calcium signaling in striatal astrocytes
    • Venance L, Piomelli D, Glowinski J, Giaume C. Inhibition by anandamide of gap junctions and intercellular calcium signaling in striatal astrocytes. Nature 1995;376:590-594.
    • (1995) Nature , vol.376 , pp. 590-594
    • Venance, L.1    Piomelli, D.2    Glowinski, J.3    Giaume, C.4
  • 129
    • 0027315816 scopus 로고
    • Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase
    • Vogel Z, Barg J, Levy R, Saya D, Heldman E, Mechoulam R. Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase. J Neurochem 1993;61:352-355.
    • (1993) J Neurochem , vol.61 , pp. 352-355
    • Vogel, Z.1    Barg, J.2    Levy, R.3    Saya, D.4    Heldman, E.5    Mechoulam, R.6
  • 130
    • 0028883207 scopus 로고
    • The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide
    • Wartmann M, Campbell D, Subramanian A, Burstein SH, Davis RJ. The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide. FEBS Lett 1995;359:133-136.
    • (1995) FEBS Lett , vol.359 , pp. 133-136
    • Wartmann, M.1    Campbell, D.2    Subramanian, A.3    Burstein, S.H.4    Davis, R.J.5
  • 131
    • 0028120958 scopus 로고
    • Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat
    • Weidenfeld J, Feldman S, Mechoulam R. Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat. Neuroendocrinology 1994;59:110-112.
    • (1994) Neuroendocrinology , vol.59 , pp. 110-112
    • Weidenfeld, J.1    Feldman, S.2    Mechoulam, R.3
  • 132
    • 0019494168 scopus 로고
    • Site and mode of action in indomethacin on the hypothalamo-hypophyseal-adrenal axis: A temporal study in intact, hypothalamic deafferentated and hypothalamic lesioned male rats
    • Weidenfled J, Siegel RA, Conforti N, Feldman S, Chowers I. Site and mode of action in indomethacin on the hypothalamo-hypophyseal-adrenal axis: a temporal study in intact, hypothalamic deafferentated and hypothalamic lesioned male rats. Endocrinology 1981;109:205-209.
    • (1981) Endocrinology , vol.109 , pp. 205-209
    • Weidenfled, J.1    Siegel, R.A.2    Conforti, N.3    Feldman, S.4    Chowers, I.5
  • 133
    • 0029009773 scopus 로고
    • Characterization of anandamide- and fluoroanandamide-induced antinociception and cross-tolerance to delta 9-THC after intrathecal administration to mice: Blockade of delta-9-THC-induced antinociception
    • Welch SP, Dunlow LD, Patrick GS, Razdan RK. Characterization of anandamide- and fluoroanandamide-induced antinociception and cross-tolerance to delta 9-THC after intrathecal administration to mice: Blockade of delta-9-THC-induced antinociception. J Phamacol Exp Ther 1995;273:1235-1244.
    • (1995) J Phamacol Exp Ther , vol.273 , pp. 1235-1244
    • Welch, S.P.1    Dunlow, L.D.2    Patrick, G.S.3    Razdan, R.K.4
  • 134
    • 0029044855 scopus 로고
    • Effects of anandamide (endogen cannabinoid) on anterior pituitary hormone secretion in adult ovariectomized rats
    • Wenger T, Toth BE, Martin BR. Effects of anandamide (endogen cannabinoid) on anterior pituitary hormone secretion in adult ovariectomized rats. Life Sci 1995;56:2057-2063.
    • (1995) Life Sci , vol.56 , pp. 2057-2063
    • Wenger, T.1    Toth, B.E.2    Martin, B.R.3
  • 135
    • 0028961790 scopus 로고
    • Discriminative stimulus effects of anandamide in rats
    • Wiley J, Balster R, Martin B. Discriminative stimulus effects of anandamide in rats. Eur J Pharmacol 1995;276:49-54.
    • (1995) Eur J Pharmacol , vol.276 , pp. 49-54
    • Wiley, J.1    Balster, R.2    Martin, B.3
  • 136
    • 0030070805 scopus 로고
    • HU-211, a nonpsychotropic cannabinoid, produces short- and long-term neuroprotection after optic nerve axotomy
    • Yoles E, Belkin M, Schwartz M. HU-211, a nonpsychotropic cannabinoid, produces short- and long-term neuroprotection after optic nerve axotomy. J Neurotrauma 1995;13:49-57.
    • (1995) J Neurotrauma , vol.13 , pp. 49-57
    • Yoles, E.1    Belkin, M.2    Schwartz, M.3


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