Resistance to gentamicin, amikacin and ciprofloxacin among nosocomial isolates of Klebsiella pneumoniae subspecie pneumoniae producing extended spectrum β-lactamases;Resistencia a gentamicina, amikacina y ciprofloxacina en cepas hospitalarias de Klebsiella pneumoniae subespecie pneumoniae productoras de β-lactamasas de espectro extendido

Revista Medica de Chile

Volumn 132, Issue 10, 2004, Pages 1173-1178

  Díaz Q, Patricia ^a,c   Bello T, Helia ^a,c   Domínguez Y, Mariana ^a,c   Trabal F, Natalia ^a,c   Mella M, Sergio ^a   Zemelman Z, Raúl ^b,c   González R, Gerardo ^a,c  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

^b UNIVERSIDAD SAN SEBASTIÁN   (Chile)

^c Bioquímico ^*

Author keywords

Aminoglycosides; Antibiotic resistance, bacterial; Klebsiella pneumoniae

Indexed keywords

ACYLTRANSFERASE; AMIKACIN; BETA LACTAMASE; CIPROFLOXACIN; GENTAMICIN; ISOENZYME; KANAMYCIN; NEOMYCIN; TOBRAMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CHILE; CONTROLLED STUDY; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION;

AMIKACIN; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; BETA-LACTAMASES; CIPROFLOXACIN; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; GENTAMICINS; HUMANS; KLEBSIELLA PNEUMONIAE;

EID: 12544257985     PISSN: 00349887     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. BRANGER C, LESIMPLE AL, BRUNEAU B, BERRY P, LAMBERT-ZECHOVSKY N. Long-term investigation of the clonal disemination of Klebsiella pneumoniae isolates producing extended-spectrum β-lactamases in a university hospital. J Med Microbiol 1998; 47: 201-9.
2. WEST PWJ. Extended-spectrum β-lactamases-producing Klebsiella spp. Br J Biomed Sci 2000; 57: 226-33.
3. RICE L. Evolution and clinical importance of extended-spectrum β-lactamases. CHEST 2001; 119: 391-6.
4. YANG Y, BHACHECH N, BRADFORD PA, JETT BD, SAHM DF, BUSH K. Ceftazidime-resistant Klebsiella pneumoniae and Escherichia coli isolates producing TEM-10 and TEM-43 β- lactamases from St. Louis, Missouri. Antimicrob Agents Chemother 1998; 42: 1671-6.
5. ZEMELMAN R, BELLO H, DOMÍNGUEZ M, GONZÁLEZ G, MELLA S, GARCÍA A. Activity of imipenem, third-generation cephalosporins, aztreonam and ciprofloxacin against multi-resistant Gram-negative bacilli isolated from Chilean hospitals. J Antimicrob Agents 1993; 32: 413-9.
6. SPANU T, LUZZARO F, PERILLI M, AMICOSANTE G, TONIOLO A, FADDA G AND THE ITALIAN ESBL STUDY GROUP. Occurrence of extended-spectrum β-lactamases in members of the family Enterobacteriaceae in Italy: Implications for resistance to β-lactams and other antimicrobial drugs. Antimicrob Agents Chemother 2002; 46: 196-202.
7. BRADFORD PA. Extended-spectrum β-lactamases in the 21st century: Characterization, epidemiology, and detection of this important resistance threat. Clin Microbiol Rev 2001; 14: 933-51.
8. BUSH K, JACOBY GA, MEDEIROS AA. A functional classification scheme for β- lactamases and correlation with molecular structure. Antimicrob Agents chemother 1995; 39: 1211-33.
9. BENNETT PM. Integrons and gene cassettes: a genetic construction kit for bacteria. J Antimicrob Chemother 1999; 43: 1-4.
10. NAAS T, NORDMANN P. OXA-type- β-lactamases. Curr Pharm Desig 1999; 5: 865-79.
11. POIREL L, NAAS T, NICOLAS D, COLLET L, BELLAIS S, CAVALLO JD ET AL. Characterization of VIM-2, a carbapenem-hydrolyzing metallo-β-lactamase and its plasmid and integron borne gene from Pseudomonas aeruginosa clinical isolate in France. Antimicrob Agents Chemother 2000; 44: 891-7.
12. MARTÍNEZ-FREIJO P, FLUIT AC, SCHMITZ FJ, VERHOEF J, JONES ME. Many class 1 integrons comprise distinct stable structures ocurring in different species of Enterobacteriaceae isolated from widespread geografic regions in Europe. Antimicrob Agents Chemother 1999; 43: 686-9.
13. th Edition. NCCLS document M7-A5. NCCLS, Wayne, Pennsylvania, USA.
14. th Edition. NCCLS document M2-A7. NCCLS, Wayne, Pennsylvania, USA.
15. MELANO R, CORSO A, PETRONI A, CENTRÓN D, ORMAN B, PEREYRA A ET AL. Multiple antibiotic-resistance mechanisms including a novel combination of extended-spectrum β-lactamases in a Klebsiella pneumoniae clinical strain isolated in Argentina. J Antimicrob Chemother 2003; 52: 36-42.
16. IMP) in Gram-negative rods resistant to broad-spectrum β-lactams. J Clin Microbiol 1996; 34: 2904-13.
17. MAZEL D, DYCHINCO B, WEBB VA, DAVIES J. Antibiotic resistance in the ECOR collection: Integrons and identification of a novel aad gene. Antimicrob Agents Chemother 2000; 44: 1568-74.
18. VAKULENKO S, MOBASHERY S. Versatility of aminoglycosides and prospects for their future. Clin Microbiol Rev 2003; 16: 430-50.
19. REYES A, BELLO H, DOMÍNGUEZ M, MELLA S, ZEMELMAN R, GONZÁLEZ G. Prevalence and types of class 1 integrons in aminoglycoside-resistant Enterobacteriaceae from several Chilean hospitals. J Antimicrob Chemother 2003; 51: 317-21.
20. MELLA S, GARCÍA A, AGUILERA L, ZEMELMAN R. Antibióticos aminoglicósidos. Agrupación según su estructura química y actualización sobre alguna de sus propiedades. Acta Microbiológica 1993; 4: 5-13.
21. MELLA S, ACUÑA G, MUÑOZ M, PERÉZ C, LABARCA J, GONZÁLEZ G ET AL. Quinolonas: Aspectos generales sobre su estructura y clasificación. Rev Chil Infect 2000; 17: 53-66.
22. ARDANUY C, LIÑARES J, DOMÍNGUEZ MA, HERNÁNDEZ- ALLÉS S, BENEDÍ VJ, MARTÍNEZ-MARTÍNEZ L. Outer membrane profiles of clonally related Klebsiella pneumoniae isolates from clinical samples and activities of cephalosporins and carbapenems. Antimicrob Agents Chemother 1998; 42: 1636-40.
23. KIM YK, PAI H, LEE HJ, PARK SE, CHOI EH, KIM J ET AL. Bloodstream infections by extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in children: epidemiology and clinical outcome. Antimicrob Agents Chemother 2002; 46: 1481-91.
24. SHANNON K, STAPLETON P, XIANG X, JOHNSON A, BEATTIE H, EL BAKRI F ET AL. Extended-spectrum β-lactamase producing Klebsiella pneumoniae strains causing nosocomial outbreaks of infection in the United Kingdom. J Clin Microbiol 1998; 36: 3105-10.
25. SIU LK, LU PL, HSUEH PR, LIN FM, CHANG S, LUH KT ET AL. Bacteremia due to extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a pediatric oncology ward: Clinical features and identification of different plasmids carrying both SHV-5 and TEM-1 genes. J Clin Microbiol 1999; 37: 4020-7.
26. DEL SOLAR E, GARCÍA A, BELLO H, DOMÍNGUEZ M, GONZÁLEZ G, ZEMELMAN R. Mecanismos enzimáticos de resistencia a antibióticos aminoglicósidos en bacilos Gram negativos de hospitales chilenos. Rev Méd Chile 1995; 123: 293-7.
27. RUIZ J. Mechanisms of resistance to quinolones: target alteration, decreased accumulation and DNA gyrase protection. J Antimicrob Chemother. 2003; 51: 1109-17.
28. MARTÍNEZ-MARTÍNEZ L, PASCUAL A, JACOBY GA. Quinolone resistance from a transferable plasmid. Lancet 1998; 351: 797-9
29. SHAW KJ, RATHER PN, HARE RS, MILLER GH. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzimes. Microbiol Rev 1993; 57: 138-63.
30. CASIN I, BORDON F, BERTIN P, COUTROT A, PODGLAJEN I, BRASSEUR R ET AL. Aminoglycoside 6′-N-acetiltransferase variants of the Ib type with altered substrate profile in clinical isolates of Enterobacter cloacae and Citrobacter freundii. Antimicrob Agents Chemother 1998; 42: 209-15.
31. WHITE PA, MELVER CJ, RAWLINSON WD. Integrons and gene cassettes in the Enterobacteriaceae. Antimicrob Agents Chemother 2001; 45: 2658-61.
32. RAHAL JJ. Extended-spectrum β-lactamases: how big is the problem? Clin Microbiol Infect 2000; 6 (Suppl. 2): 2-6.
33. MAHGOUB S, AHMED J, GLATT AE. Completely resistant Acinetobacter baumannii strains. Infect Control Hosp Epidemiol 2002; 23: 477-9.
34. OLIVER A. Resistencia a carbapenemas y Acinetobacter baumannii. Enferm Infecc Microbiol Clin 2004; 22: 259-61.