Ischemia and hypoxia. An attempt to explain the different rates of retinal ganglion cell death in glaucoma;Ischämie und hypoxie: Ein erklärungsversuch zur unterschiedlichen absterberate retinaler ganglienzellen bei glaukom

Ophthalmologe

Volumn 101, Issue 11, 2004, Pages 1071-1075

  Schmidt, K G ^a   Pillunat, L E ^a   Osborne, N N ^b  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

GABA; Glutamate; Neuroprotective treatment; Neurotransmitter; Primary chronic open angle glaucoma; Receptor profile

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CELL RECEPTOR; CHOLINERGIC RECEPTOR BLOCKING AGENT; CHOLINERGIC RECEPTOR STIMULATING AGENT; GLUTAMATE RECEPTOR; GLUTAMIC ACID; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; NEUROTRANSMITTER; NEUROTRANSMITTER RECEPTOR;

CELL DEATH; CELL HYPOXIA; DEPOLARIZATION; GLAUCOMA; ISCHEMIA; NEUROPROTECTION; OPEN ANGLE GLAUCOMA; OPTIC NERVE DISEASE; RETINA GANGLION CELL; REVIEW; SENSITIVITY ANALYSIS;

ANIMALS; ANOXIA; APOPTOSIS; GLAUCOMA, OPEN-ANGLE; HUMANS; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; NEUROTRANSMITTER AGENTS; OPTIC NEUROPATHY, ISCHEMIC; RETINAL DEGENERATION; RETINAL GANGLION CELLS;

EID: 12444281772     PISSN: 0941293X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00347-004-1131-0     Document Type: Review

References (42)

1. Anderson RS, O'Brien C (1997) Psychophysical evidence for a selective loss of M ganglion cells in glaucoma. Vision Res 37:1079-1083
2. Baldridge WH (1996) Optical recordings of the effects of cholinergic ligands on neurons in the ganglion cell layer of mammalian retina. J Neurosci 16:5060-5072
3. Better B, Mulle C (1995) Review: neurotransmitter receptors. IL AMPA and kainate receptors. Neuropharmacology 34:123-139
4. Brunken WJ, Jin XT, Pis-Lopez AM (1993) The properties of the serotonergic system in the retina. In: Osborne NN, Chader GJ (eds) Progress in Retinal Research. Pergamon, Oxford, S 75-100
5. Caprioli J, Kitano S (1993) Large ganglion cells are more susceptible to excitotoxic and hypoxic injury than small cells. Invest Ophthalmol Vis Sci 34:1429-1434
6. Cazevielle C, Osborne NN (1997) Retinal neurones containing kainate receptors are influenced by exogenous kainate and ischaema is while neurones lacking these receptors are not - melatonin counteracts the effect of ischaema and kainate. Brain Res 755:91-100
7. 2+-independentexcitotoxic neurodegeneration in isolated retina, an intact neural net: a role for Cl and inhibitory transmitters. Mol Pharmacol 53:564-572
8. Dreyer EB, Pan ZH, Storm S, Lipton SA (1994) Greater sensitivity of larger retinal ganglion cells to NMDA-mediated cell death. Neuroreport 5:629-631
9. Dreyer EB, Zurakowski D, Schumer RA, Podos SM, Lipton SA (1996) Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol 114:299-305
10. Fechtner RD, Weinreb RN (1994) Mechanisms of optic nerve damage in primary open angle glaucoma. Surv Ophthalmol 39:23-42
11. Flammer J (1995) To what extent are vascular factors involved in the pathogenesis of glaucoma? In: Kaiser HJ, Flammer J, Hendrickson P (Hrsg) Ocular Blood Flow. Glaucoma meeting. Karger, Basel, S 12-39
12. Galzi JL, Changeux JP (1995) Neuronal nicotinic receptors: molecular organization and regulations. Neuropharmacology 34:563-582
13. Hessemer V, Schmidt KG (1997) Influence of the vasodilator drug isosorbide dinitrate on ocular circulation. Arch Ophthalmol 115:324-327
14. Klingmüller V, Schmidt KG, v Rückmann A, Gumbrecht S, Stein A, Koch B (2000) Farb- und Spektral-Doppler-sonographische Perfusionsmessungen in den kurzen hinteren Ziliararterien bei gesunden Probanden. In: Schmidt KG, Pillunat LE (Hrsg) Fortbildung Glaukom, Bd 3. Enke, Stuttgart, S 29-38
15. Lipton SA (1988) Spontaneous release of acetylcholine affects the physiological nicotinic responses of rat retinal ganglion cells in culture. J Neurosci 8:3857-3868
16. Lukasiewicz PD, Shields CR (1998) Different combinations of GABAA and GABAc receptors confer distinct temporal properties to retinal synaptic responses. J Neurophysiol 79:3157-3167
17. Lyden PD (1997) GABA and neuroprotection. Int Rev Neurobiol 40:47-70
18. Mori H, Mishina M (1995) Structure and function of the NMDA receptor channel. Neuropharmacology 34:1219-1237
19. Müller A, Villain M, Bonne C (1997) The release of amino acids from ischémic retina (letter). Exp Eye Res 64:291-293
20. Nguyen Legros J, Simon A, Caille I, Bloch B (1997) Immunocytochemical localization of dopamine D1 receptors in the retina of mammals. Vis Neurosci 14:545-551
21. Obrenovitch TP, Richards DA (1995) Extracellular neurotransmitter changes in cerebral ischaemia. Cerebrovasc Brain Metab Rev 7:1-54
22. Osborne NN, Ugarte M, Chao M, Chidlow G, Bae JH, Wood JPM, Nash MS (1999) Neuroprotection in relation to retinal ischemia and relevance to glaucoma. Surv Ophthalmol 43 [Suppl 1]:S102-S128
23. Osborne NN, Wood JR Chidlow G, Bae JH, Melena J, Nash MS (1999) Ganglion cell death in glaucoma: what do we really know? Br J Ophthalmol 83:980-986
24. Osborne NN, DeSantis L, Melena J, Chidlow G, Wood JPM (2000) Attenuation of ganglion cell dysfunction. Ophthal Clin North Am 13:123-130
25. Osborne NN, Chidlow G, Wood JPM, Schmidt KG, Casson R, Melena J (2001) Expectations in the treatment of retinal diseases: neuroprotection. Curr Eye Res 22:321-332
26. Otori Y, Wei JY, Barnstable CJ (1998) Neurotoxic effects of low doses of glutamate on purified rat retinal ganglion cells. Invest Ophthalmol Vis Sci 39:972-981
27. Pillunat LE, Stodtmeister R, Willmanns I (1987) Pressure compliance of the optic nerve head in low tension glaucoma. Br J Ophthalmol 71:181-187
28. Pillunat LE, Stodtmeister R, Marquardt R, Mattern A (1989) Ocular perfusion pressures in different types of glaucoma. Int Ophthalmol 13:37-42
29. Quigley HA, Sanchez RM, Dunkelberger GR, Baginski TA (1987) Chronic glaucoma selectively damages large optic nerve fibers. Invest Ophthalmol Vis Sci 28:913-920
30. Quigley HA, Nickells RW, Kerigan LA et al (1995) Retinal cell ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Invest Ophthalmol Vis Sci 36:774-786
31. Schmidt KG, Stegman DY, Serie JB et al. (1991) Ocular pulse amplitude in primary open-angle glaucoma, low tension glaucoma, and in ocular hypertensive patients before and after topical drug treatment. Invest Ophthalmol Vis Sci 32 [Suppl]:943
32. Schmidt KG, Mittag TW, Pavlovic S, Hessemer V (1996) Influence of physical exercise and nifedipine on ocular pulse amplitude. Graefes Arch Clin Exp Ophthalmol 234:527-532
33. Schmidt KG, v. Rückmann A, Geyer O, Mittag TW (1997) Einfluß des Nifedipins auf die okuläre Pulsamplitude bei Normaldruckglaukom. Klin Monatsbl Augenheilkd 210:355-359
34. Schmidt KG, v Rückmann A, Mittag TW, Hessemer V, Pillunat LE (1997) Reduced ocular pulse amplitude in low-tension glaucoma is independent of vasospasm. Eye 11:485-488
35. Schmidt KG, v Rückmann A, Pillunat LE (1998) Dorzolamide increases ocular pulse amplitude in high tension primary open angle glaucoma. Br J Ophthalmol 82:758-762
36. Schmidt KG (1999) Antiglaukomatosa und choroidale Perfusion bei primärem und experimentell induziertem Offenwinkelglaukom. In: Schmidt KG, Pillunat LE (Hrsg) Fortbildung Glaukom, Bd 1, Perfusion und Pharmakologie. Enke, Stuttgart, S 39-50
37. Schmidt KG, Klingmüller V, v Rückmann A, Koch B (2000) Retrobulbäre und chorioidale Hämodynamik bei Hochdruck- und Normaldruckglaukom. In: Schmidt KG, Pillunat LE (Hrsg) Fortbildung Glaukom, Bd 3. Enke, Stuttgart, S 103-114
38. Schmidt KG, Klingmüller V, Gouveia SM, Osborne NN, Pillunat LE (2003) Short posterior ciliary artery, central retinal artery, and choroidal hemodynamics in brimonidine-treated primary open-angle glaucoma patients. Am J Ophthalmol 136:1038-1048
39. Schmidt KG, Geyer O, Mittag TW (2004) Adenylyl and guanylyl cyclase activity in the choroid. Exp Eye Res 78:901-907
40. Shimohama S, Akaike A, Kimura J (1996) Nicotine-induced protection against glutamate cytotoxicity. Nicotinic cholinergic receptor-mediated inhibition of nitric oxide formation. Ann N Y Acad Sci 777:356-361
41. Shuaib A, Murabit MA, Kanthan R, Hewlett W, Wishart T (1996) The neuroprotective effects of gamma-vinyl GABA in transient global ischemia: a morphological study with early and delayed evaluations. Neurosci Lett 204:1-4
42. Steinsapir KD, Goldberg RA (1994)Traumaticoptic neuropathy. Surv Ophthalmol 38:487-518