Genetic determinants of fasting and post-methionine hyperhomocysteinemia in patients with retinal vein occlusion

Thrombosis Research

Volumn 110, Issue 1, 2003, Pages 7-12

  Marcucci, Rossella ^a   Giusti, Betti ^a   Betti, Irene ^a   Evangelisti, Lucia ^a   Fedi, Sandra ^a   Sodi, Andrea ^a   Cappelli, Stefania ^a   Menchini, Ugo ^a   Abbate, Rosanna ^a   Prisco, Domenico ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Genetic polymorphisms; Homocysteine; Methionine loading; Retinal vein occlusion

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYSTATHIONINE BETA SYNTHASE; METHIONINE;

ADULT; AGED; ARTERY THROMBOSIS; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; GENETIC POLYMORPHISM; HUMAN; HYPERHOMOCYSTEINEMIA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETINA VEIN OCCLUSION; RISK FACTOR; VEIN THROMBOSIS;

EID: 12444273299     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(03)00293-7     Document Type: Article

References (33)

1. Boushey C.J., Beresford S.A., Omenn G.S., Motulsky A.G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of increasing folic acid intakes. JAMA. 274:1995;1049-1057.
2. Vine A.K. Hyperhomocysteinemia: a risk factor for central retinal vein occlusion. Am. J. Ophthalmol. 129:2000;640-644.
3. Marcucci R., Bertini L., Giusti B.et al. Thrombophilic risk factors in patients with central retinal vein occlusion. Thromb. Haemost. 86:2001;1-5.
4. Wenzler E.M., Rademakers A.J.J.M., Boers G.H.J.et al. Hyperhomocysteinemia in retinal artery and retinal vein occlusion. Am. J. Ophthalmol. 115:1993;162-167.
5. De Bruijne E.L.E., Keulen-de Vos G.H.J.C., Ouwendijik R.J.T. Ocular venous occlusion and hyperhomocysteinemia. Ann. Intern. Med. 130:1999;78.
6. Cahill M., Karabatzaki M., Meleady R.et al. Raised plasma homocysteine as a risk factor for retinal vascular occlusive disease. Br. J. Ophthalmol. 84:2000;154-157.
7. Pianka P., Almog Y., Man O.et al. Hyperhomocystinemia in patients with nonarteritic anterior ischemic optic neuropathy, central retinal artery occlusion, and central retinal vein occlusion. Ophthalmology. 107:2000;1588-1592.
8. Hansen L., Kristensen H.L., Bek T.et al. Markers of thrombophilia in retinal vein thrombosis. Acta Ophthalmol. Scand. 78:2000;523-526.
9. Salomon O., Moisseiev J., Rosenberg N.et al. Analysis of genetic polymorphisms related to thrombosis and other risk factors in patients with retinal vein occlusion. Blood Coagul. Fibrinolysis. 9:1998;617-622.
10. Larsson J., Hultberg B., Hillarp A. Hyperhomocysteinemia and the MTHFR C677T mutation in central retinal vein occlusion. Acta Ophthalmol. Scand. 78:2000;340-343.
11. Cahill M., Karabatzaki M., Donoghue C.et al. Thermolabile MTHFR genotype and retinal vascular occlusive disease. Br. J. Ophthalmol. 85:2001;88-90.
12. Brown B.A., Marx J.L., Ward T.P.et al. Homocysteine as a risk factor for retinal venous occlusive disease. Ophthalmology. 109:2002;287-290.
13. Lahey L.M., Tunc M., Kearney J.et al. Laboratory evaluation of hypercoagulable states in patients with central retinal vein occlusion who are less than 56 years of age. Ophthalmology. 109:2002;126-131.
14. Boyd S., Owens D., Gin T.et al. Plasma homocysteine, methylene tetrahydrofolate reductase C677T and factor VIII, and VWF in central retinal vein occlusion. Br. J. Ophthalmol. 85:2001;1313-1315.
15. Weger M., Stanger O., Haas A. Hyperhomocysteinemia: a risk factor for central retinal vein occlusion. Am. J. Ophthalmol. 131:2001;290-291.
16. Glueck C.J., Bell H., Vadlamani L.et al. Heritable thrombophilia and hypofibrinolysis. Possible causes of retinal vein occlusion. Arch. Ophthalmol. 117:1999;43-49.
17. Biousse V., Newman N.J., Sternberg P. Jr. Retinal vein occlusion and transient monocular visual loss associated with hyperhomocystinemia. Am. J. Ophthalmol. 124:1997;257-260.
18. Ducloux D., Bresson-Vautrin C., Dhalopin J.M. Ocular venous occlusion and hyperhomocysteinemia. Ann. Intern. Med. 131:1999;548.
19. Brattstrom L. Common mutation in the methylenetetrahydrofolate reductase gene offers no support for mild hyperomhocisteinemia being a casual risk factor for cardiovascular disease. Circulation. 96:1997;3805-3806.
20. De Franchis R., Fermo I., Mazzola G.et al. Contribution of the cystathionine β-synthase gene (844ins68) polymorphism to the risk of early-onset venous and arterial occlusive disease and of fasting hyperhomocysteinemia. Thromb. Haemost. 84:2000;576-582.
21. Abbate R., Sardi I., Pepe G.et al. The high prevalence of thermolabile 5-10 methylenetetrahydrofolate reductase (MTHFR) in Italians is not associated to an increased risk for coronary artery disease. Thromb. Haemost. 79:1998;727-730.
22. Arruda V.R., Von Zuberv P.M., Ciapaini L.C.et al. The mutation Ala 677-Val in the MTHFR gene: a risk factor for arterial disease and venous thrombosis. Thromb. Haemost. 77:1997;818-821.
23. Van Bockxmeer F.M., Marmotte C.D.S., Vasikaran S.D.et al. Methylenetetrahydrofolate reductase gene and coronary artery disease. Circulation. 95:1997;21-23.
24. D'Angelo A., Tavola A., Fermo I.et al. Moderate hyperhomocysteinemia and central retinal vein occlusion. Thromb. Haemost. 87:2002;1078-1079.
25. Giusti B., Camacho-Vanegas O., Attanasio M.et al. Microheterogeneity in the distribution of the 844 ins 68 in the cystationine β-synthase gene in Italy. Thromb. Res. 94:1999;249-254.
26. Bostom A.G., Jacques P.F., Nadeau M.R.et al. Post-methionine load hyperhomocysteinemia in persons with normal fasting total plasma homocysteine: initial results from The NHLBI Family Heart Study. Atherosclerosis. 116:1995;147-151.
27. Van den Berg M., de Jong S., Deville' W.et al. Variability of fasting and post-methionine plasma homocysteine levels in normo- and hyperhomocysteinemic individuals. Neth. J. Med. 55:1999;29-38.
28. Van der Griend R., Haas F.J.L., Duran M.et al. Methionine loading test is necessary for detection of hyperhomocysteinemia. J. Lab. Clin. Med. 132:1998;67-72.
29. Cattaneo M., Lombardi R., Lecchi A.et al. Is the oral methionine loading test insensitive to the remethylation pathway of homocysteine? Blood. 93:1999;1118-1120.
30. Adamczuk Y.P., Iglesias Varela M.L., Martinuzzo M.E.et al. Central retinal vein occlusion and thrombophilia risk factors. Blood Coagul. Fibrinolysis. 13:2002;623-626.
31. Egerton W., Silberg J., Crooks R., Ray C., Xie L., Dudman N. Serial measures of plasma homocysteine after acute myocardial infarction. Am. J. Cardiol. 77:1996;759-761.
32. Lindgren A., Brattstrom L., Norving B.et al. Plasma homocysteine in the acute and convalescent phases after stroke. Stroke. 26:1995;795-800.
33. Robinson K., Arheart K., Retium H.et al. Low circulating folate and vitamin B6 concentration: risk factors for stroke, peripheral vascular disease and coronary artery disease. Circulation. 97:1998;437-443.