Structure-activity relationships in a series of NPY Y5 antagonists: 3-Amido-9-ethylcarbazoles, core-modified analogues and amide isosteres

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 12, 2003, Pages 1989-1992

  Hammond, Marlys ^a   Elliott, Richard L ^a   Gillaspy, Melissa L ^a   Hager, David C ^a   Hank, Richard F ^a   LaFlamme, Janet A ^a   Oliver, Robert M ^a   DaSilva Jardine, Paul A ^a   Stevenson, Ralph W ^a   Mack, Christine M ^b   Cassella, James V ^b  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^b NEUROGEN CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; CARBAZOLE DERIVATIVE; FUNCTIONAL GROUP; IMIDAZOLE; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y5 RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG SOLUBILITY; DRUG SYNTHESIS; MALE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

EID: 12444265788     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00329-9     Document Type: Article

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