Presence of immunoglobulins and antigens in serum, lung and small intestine in Ascaris suum infected and immunised pigs

Veterinary Parasitology

Volumn 119, Issue 1, 2004, Pages 59-71

  Frontera, E ^a   Roepstorff, A ^b   Serrano, F J ^a   Gazquez A ^a   Reina, D ^a   Navarrete, I ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Antigens; Ascaris suum; ELISA; Immunoglobulins; Immunohistochemistry; Nematoda; Pig

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PARASITE ANTIBODY; PARASITE ANTIGEN; PYRANTEL EMBONATE; VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN DETECTION; ARTICLE; ASCARIASIS; ASCARIS SUUM; BODY FLUID; BRONCHUS; CELL COUNT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DUODENUM; EGG; EOSINOPHIL; EXPERIMENTAL INFECTION; FEMALE; IMMUNIZATION; IMMUNODETECTION; LAMINA PROPRIA; LARVA; LEUKOCYTE COUNT; LUNG; LUNG GRANULOMA; NONHUMAN; PARASITE IMMUNITY; REINFECTION; SERUM; SMALL INTESTINE; SWINE; SWINE DISEASE;

ANIMALIA; ASCARIS SUUM; NEMATODA; SUS SCROFA;

EID: 1242351608     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetpar.2003.09.022     Document Type: Article

References (36)

1. Allen W.D., Porter P. The relative frequencies and distribution of immunoglobulin bearing cells in the intestinal mucosa of neonatal and weaned pigs and their significance in the development of secretory immunity. Immunology. 32:1977;819-824.
2. Atkins A.M., Schofield G.C.S., Reeders T. Studies on the structure and distribution of immunoglobulin-containing cells in the gut of the pig. Vet. Rec. 98:1971;499-501.
3. Boes J., Coates S., Medley G.F., Varady M., Eriksen L., Roepstorff A., Nansen P. Exposure of sows to Ascaris suum influences worm burden distributions in experimentally infected suckling piglets. Parasitology. 119:1999;509-520.
4. Brown P.J., Bourne F.J. Development of immunoglobulin-containing cell populations in intestine, spleen and mesenteric lymph node of the young pig as demonstrated by peroxidase-conjugated antiserum. Am. J. Vet. Res. 37:1976;1309-1314.
5. Butler J.E. Immunoglobulin diversity, B-cell and antibody repertoire development in large farm animals. Rev. Sci. Tech. Utt. Int. Epiz. 17(1):1998;43-70.
6. Copeman, D.B., 1971. Immunopathological responses of pigs in ascariasis. In: Gaafar, S.M. (Ed.), Pathology of Parasitic Diseases. Purdue University Studies, Lafayette, Indiana, pp. 135-145.
7. Douvres F.W., Tromba F.G., Malakatis G.M. Morphogenesis and migration of Ascaris suum larvae developing to fourth stage in swine. J. Parasitol. 55:1969;689-712.
8. Eriksen, L., 1981. Host parasite relations in Ascaris suum infection in pigs and mice. Royal Veterinary and Agricultural University. Commissioned by Carl F. Mortensen, Copenhagen.
9. Fagerholm H.P., Nansen P., Roepstorff A., Frandsen F., Eriksen L. Differentiation of cuticular structures during the growth of the third-stage larva of Ascaris suum (Nematoda Ascaridoidea) after emerging from the egg. J. Parasitol. 86(3):2000;421-427.
10. Frontera E., Roepstorff A., Gázquez A., Reina D., Serrano F.J., Navarrete I. Immunohistochemical distribution of antigens in liver of infected and immunized pigs with Ascaris suum. Vet. Parasitol. 111:2003;9-18.
11. Geenen P.L., Bresciani J., Boes J., Pedersen A., Eriksen L., Fagerholm H.P., Nansen P. The morphogenesis of Ascaris suum to the infective third-stage larvae within the egg. J. Parasitol. 85(4):1999;616-622.
12. Guerrero J., Silverman P.H. Ascaris suum: immune reactions in mice. I. Larval metabolic and somatic antigens. Exp. Parasitol. 26:1969;272-281.
13. Helwigh A.B., Nansen P. Establishment of Ascaris suum in the pig: development of immunity following a single primary infection. Acta Vet. Scand. 40:1999;121-132.
14. Hill, D.E., Fetterer, R.H., Urban, J.F., 1990. Lymphocyte activation by Ascaris suum cuticular antigens in vitro (Abstract). In: Proceedings of the 35th Annual Meeting of American Association of Veterinary Parasitology, San Antonio, TX, p. 45.
15. Hill D.E., Fetterer R.H., Romanowski R.D., Urban J.F. The effect of immunization of pigs with Ascaris suum cuticle components on the development of resistance to parenteral migration during a challenge infection. Vet. Immunol. Immunopathol. 42:1994;161-169.
16. Jungersen, G., 1998. Experimental Ascaris suum infections. Manipulated infections and immune responses to larval migration in pigs. PhD Thesis. Royal Veterinary and Agricultural University, Copenhagen.
17. Jungersen, G., 2002. Immunity and immune responses to Ascaris suum in pigs. In: Holland, C.V., Kennedy, M.W. (Eds.), The Geohelminths: Ascaris, Trichuris and Hookworm. Kluwer Academic Publishers, London, pp. 105-124.
18. Kelley G.W., Nayak D.P. Passive immunity to Ascaris suum transferred in colostrum from sows to their offspring. Am. J. Vet. Res. 26:1965;948-950.
19. Kelley G.W., Nayak D.P. Passive immunity to migrating Ascaris suum transmitted by parenterally administered immune serum or immune globulins. Cornell Vet. 55:1965;607-612.
20. Kennedy M.W., Qureshi F. Stage-specific secreted antigens of the parasitic larval stages of the nematode Ascaris. Immunology. 58:1986;515-522.
21. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
22. Lind P., Eriksen L., Nansen P., Nilsson O., Roepstorff A. Response to repeated inoculations with Ascaris suum eggs in pigs during the fattenig period. II. Specific IgA, IgG, and IgM antibodies determined by enzyme-linked immunosorbent assay. Parasitol. Res. 79:1993;240-244.
23. Marbella C.O., Gaafar S.M. Production and distribution of immunoglobulin bearing cells in the intestine of young pigs infected with Ascaris suum. Vet. Parasitol. 34:1989;63-70.
24. McKerrow J.H. Minireview: parasite proteases. Exp. Parasitol. 68:1989;111-115.
25. Murrell K.D., Eriksen L., Slotved H.C., Rasmussen T. Ascaris suum: a revision of its early migratory path and implications for human ascariasis. J. Parasitol. 83(2):1997;255-260.
26. Pérez J., Garcia P.M., Mozos E., Bautista M.J., Carrasco L. Immunohistochemical characterization of hepatic lesions associated with migrating larvae of Ascaris suum in pigs. J. Comp. Pathol. 124:2001;200-206.
27. Roberts, F.H.S., 1934. The large roundworm of pigs Ascaris lumbricoides L. 1758. Its life history in Qeensland, Australia, economic importance and control. Yeerongpilly Animal Health Station Bulletin No. 1, pp. 1-81.
28. Roepstorff A., Eriksen L., Slotved H.C., Nansen P. Experimental Ascaris suum infection in the pig: worn population kinetics following single inoculations with three doses of infective eggs. Parasitology. 115:1997;443-452.
29. Roneus O. Studies on the aetiology and pathogenesis of white spots in the liver of pigs. Acta Vet. Scand. 16(Suppl. 7):1966;7-112.
30. Serrano F.J., Pérez-Martín E., Reina D., Navarrete I. Trichinella strain, pig race and other parasitic infections as factors in the reliability of ELISA for the detection of swine trichinellosis. Parasitology. 105:1992;111-115.
31. Serrano F.J., Reina D., Frontera E., Navarrete I., Roepstorff A. Resistance against migrating Ascaris suum larvae in pigs immunised with adult worm antigens. Parasitology. 105:2001;111-115.
32. Stromberg B.E. The isolation and partial characterization of a protective antigen from developing larvae of Ascaris suum. Int. J. Parasitol. 9:1979;307-311.
33. Taffs L.F. Immunological studies on experimental infection of pigs with A. suum Goeze, 1782. VI. The histopathology of the liver and lung. J. Helminthol. 42:1968;157-172.
34. Urban J.F. The epidemiology and control of swine parasites. Vet. Clin. N. Am-Food A. 2:1986;765-778.
35. Urban J.F., Romanowski R.D. Ascaris suum: protective immunity in pigs immunized with products form eggs and larvae. Exp. Parasitol. 60:1985;245-254.
36. Urban J.F., Alizadeh H., Romanowski R.D. Ascaris suum: development of intestinal immunity to infective second-stage larvae in swine. Exp. Parasitol. 66:1988;66-77.