Epilepsy and manganese [5]

Lancet

Volumn 363, Issue 9408, 2004, Pages 572-

  Grant, Ellen C G ^a  

^a NONE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ANTICONVULSIVE AGENT; BRAIN MONOAMINE; COPPER; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; GLUTATHIONE PEROXIDASE; MAGNESIUM; MANGANESE; PSYCHOTROPIC AGENT; SUPEROXIDE DISMUTASE; TOXIC SUBSTANCE; ZINC;

ASTROCYTE; BRAIN TISSUE; COPPER DEFICIENCY; DIET SUPPLEMENTATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME DEFICIENCY; FOOD ALLERGY; HIPPOCAMPUS; HUMAN; LATENT PERIOD; LETTER; LUPIN; MAGNESIUM DEFICIENCY; MINERAL BLOOD LEVEL; NONHUMAN; NUTRIENT CONCENTRATION; PRIORITY JOURNAL; SEIZURE SUSCEPTIBILITY; SMOKING; TEMPORAL LOBE EPILEPSY; TISSUE LEVEL; ANIMAL; BLOOD; EPILEPSY; NOTE; RAT;

ANIMALS; EPILEPSY; HUMANS; MANGANESE; RATS;

EID: 1242340356     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(04)15558-X     Document Type: Letter

References (5)

1. Eid T., Thomas M.J., Spencer D.D., et al. Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy. Lancet. 363:2004;28-37.
2. Sohler A., Pfeiffer C.C. A direct method for the determination of manganese in whole blood. Patients with seizure activity have low blood levels. J Orthomol Psych. 8:1979;275-280.
3. Dendle P. Lupines, manganese, and devil-sickness: an Anglo-Saxon medical response to epilepsy. Bull Hist Med. 75:2001;91-101.
4. Carl G.F., Keen C.L., Gallagher B.B., et al. Association of low blood manganese concentrations with epilepsy. Neurology. 36:1986;1584-1587.
5. Critchfield J.W., Carl G.F., Keen C.L. The influence of manganese supplementation on seizure onset and severity, and brain monoamines in genetically epilepsy prone rats. Epilepsy Res. 14:1993;3-10.