Development of novel lipid-peptide hybrid compounds with antibacterial activity from natural cationic antibacterial peptides

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 5, 2004, Pages 1109-1113

  Oh, Hyun Sik ^a   Kim, Seunghee ^a   Cho, Hyeongjin ^a   Lee, Keun Hyeung ^a  

^a Inha University   (South Korea)

Author keywords

Antibacterial peptide; Lipid peptide hybrid compound; Net positive charge; Stability; Structural parameters

Indexed keywords

ACETIC ACID DERIVATIVE; AMINOCAPROIC ACID DERIVATIVE; ANTIINFECTIVE AGENT; BENZOIC ACID DERIVATIVE; DEPSIPEPTIDE; FATTY ACID; FATTY ACID DERIVATIVE; GLYCINE; LEUCINE; LYSINE; LYSYLLYSYLTYROSYLCYSTEINYLASPARAGINYLGLYCYLLYSYLARGINYLVALYLCYSTEINYLVALYLC YSTEINYLARGININAMIDE; LYSYLLYSYLTYROSYLISOLEUCYLLYSYLVALYLPHENYLALANYLVALYLPHENYLALANYLLYSINAMIDE; LYSYLPHENYLALANYLTYROSYLCYSTEINYLASPARAGINYLGLYCYLLYSYLARGINYLVALYLCYSTEINY LVALYLCYSTEINYLARGININAMIDE; LYSYLTYROSYLCYSTEINYLASPARAGINYLGLYCYLLYSYLARGINYLVALYLCYSTEINYLVALYLCYSTEI NYLARGININAMIDE; PALMITOLEIC ACID DERIVATIVE; PEPTIDE DERIVATIVE; PHENYLALANINE; PHENYLALANYLTYROSYLCYSTEINYLASPARAGINYLGLYCYLLYSYLARGINYLVALYLCYSTEINYLVALY LCYSTEINYLARGININAMIDE; PROLINE; SERINE; TYROSYLCYSTEINYLASPARAGINYLGLYCYLLYSYLARGINYLVALYLCYSTEINYLVALYLCYSTEINYLAR GININAMIDE; UNCLASSIFIED DRUG; VALINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BETA SHEET; BIOAVAILABILITY; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; MOUSE; NONHUMAN; STAPHYLOCOCCUS AUREUS;

ILEX COOKII; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 1242339559     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.12.085     Document Type: Article

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