메뉴 건너뛰기




Volumn 5, Issue 2, 2004, Pages 349-360

The role of vasoactive drugs in the treatment of oesophageal varices

Author keywords

Oesophageal varices; Portal hypertension; Variceal bleeding; Vasoactive drugs

Indexed keywords

2 PYRIDYLCARBAMIC ACID 2 [[5 (2 METHOXYPHENOXY) 6 [[(4 ISOPROPYLPHENYL)SULFONYL]AMINO] 2 MORPHOLINO 4 PYRIMIDINYL]OXY]ETHYL ESTER; 2 [[2 [[2 [[(HEXAHYDRO 1H AZEPIN 1 YL)CARBONYL]AMINO] 4 METHYLPENTANOYL]AMINO] 3 (1 METHYL 1H INDOL 3 YL)PROPIONYL]AMINO] 3 (2 PYRIDYL)PROPIONIC ACID; ANGIOPEPTIN; BOSENTAN; CAPTOPRIL; CARVEDILOL; CLONIDINE; DARUSENTAN; GLYCERYL TRINITRATE; ISOSORBIDE 5 NITRATE; ISOSORBIDE DINITRATE; LOSARTAN; NADOLOL; NCX 1000; NIPRADILOL; OCTREOTIDE; PRAZOSIN; PROPRANOLOL; SOMATOSTATIN; SPIRONOLACTONE; TERLIPRESSIN; TIMOLOL; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID DERIVATIVE; VAPREOTIDE; VASOACTIVE AGENT; VASOPRESSIN;

EID: 1242319261     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.5.2.349     Document Type: Review
Times cited : (16)

References (82)
  • 2
    • 0031777845 scopus 로고    scopus 로고
    • Clinical events after transjugular intrahepatic portosystemic shunt: Correlation with hemodynamic findings
    • CASADO M, BOSCH J, GARCIA-PAGAN JC, BRU C et al.: Clinical events after transjugular intrahepatic portosystemic shunt: correlation with hemodynamic findings: Gastroenterology (1998) 114:1296-1303.
    • (1998) Gastroenterology , vol.114 , pp. 1296-1303
    • Casado, M.1    Bosch, J.2    Garcia-Pagan, J.C.3    Bru, C.4
  • 3
    • 0033403318 scopus 로고    scopus 로고
    • Pharmacological treatment of portal hypertension: An evidence-based approach
    • D'AMICO G, PAGLIARO L, BOSCH J: Pharmacological treatment of portal hypertension: an evidence-based approach: Semin. Liver Dis. (1999) 19:475-505.
    • (1999) Semin. Liver Dis. , vol.19 , pp. 475-505
    • D'Amico, G.1    Pagliaro, L.2    Bosch, J.3
  • 4
    • 0033450924 scopus 로고    scopus 로고
    • Biology of hepatic stellate cells and their possible relevance in the pathogenesis of portal hypertension in cirrhosis
    • PINZANI M, GENTILINI P: Biology of hepatic stellate cells and their possible relevance in the pathogenesis of portal hypertension in cirrhosis. Semin. Liver Dis. (1999) 19:397-410.
    • (1999) Semin. Liver Dis. , vol.19 , pp. 397-410
    • Pinzani, M.1    Gentilini, P.2
  • 5
    • 0036154951 scopus 로고    scopus 로고
    • The paradox of nitric oxide in cirrhosis and portal hypertension: Too much, not enough
    • WIEST R, GROSZMANN RJ: The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough. Hepatology (2002) 35:478-491.
    • (2002) Hepatology , vol.35 , pp. 478-491
    • Wiest, R.1    Groszmann, R.J.2
  • 6
    • 0021522551 scopus 로고
    • Role of humoral factors in the intestinal hyperemia associated with chronic portal hypertension
    • BENOIT JN, BARROWMAN JA, HARPER SL, KVIETYS PR, GRANGER DN: Role of humoral factors in the intestinal hyperemia associated with chronic portal hypertension: Am. J. Physiol. (1984) 247:G486-G493.
    • (1984) Am. J. Physiol. , vol.247
    • Benoit, J.N.1    Barrowman, J.A.2    Harper, S.L.3    Kvietys, P.R.4    Granger, D.N.5
  • 7
    • 0033427391 scopus 로고    scopus 로고
    • Nitric oxide and portal hypertension: Its role in the regulation of intrahepatic and splanchnic vascular resistance
    • WIEST R, GROSZMANN RJ: Nitric oxide and portal hypertension: its role in the regulation of intrahepatic and splanchnic vascular resistance. Semin. Liver Dis. (1999) 19:411-426.
    • (1999) Semin. Liver Dis. , vol.19 , pp. 411-426
    • Wiest, R.1    Groszmann, R.J.2
  • 8
    • 0027938229 scopus 로고
    • Hyperdynamic circulation of liver disease 40 years later: Pathophysiology and clinical consequences
    • (editorial comment)
    • GROSZMANN RJ: Hyperdynamic circulation of liver disease 40 years later: pathophysiology and clinical consequences (editorial comment). Hepatology (1994) 20:1359-1363.
    • (1994) Hepatology , vol.20 , pp. 1359-1363
    • Groszmann, R.J.1
  • 10
    • 0042322991 scopus 로고    scopus 로고
    • Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators
    • D'AMICO G, DE FRANCHIS R: Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators. Hepatology (2003) 38:599-612.
    • (2003) Hepatology , vol.38 , pp. 599-612
    • D'Amico, G.1    Defranchis, R.2
  • 11
    • 1242325978 scopus 로고    scopus 로고
    • Multicenter randomized placebo controlled trial of non selective beta-blockers in the prevention of the complications of portal hypertension. Final results and identification of a predictive factor
    • Boston, USA (October ), Abstract 103
    • GROSZMANN RJ, GARCIA-TSAO G, BOSCH J et al.: Multicenter randomized placebo controlled trial of non selective beta-blockers in the prevention of the complications of portal hypertension. Final results and identification of a predictive factor. Proceedings of the annual meeting of the American Association for the Study of the Liver (AASLD), Boston, USA (October 2003), Abstract 103.
    • (2003) Proceedings of the Annual Meeting of the American Association for the Study of the Liver (AASLD)
    • Groszmann, R.J.1    Garcia-Tsao, G.2    Bosch, J.3
  • 12
    • 1242303478 scopus 로고    scopus 로고
    • Beta-blockers in the prevention of aggravation of esophageal varices in patients with cirrhosis and small varices: A placebocontrolled clinical trial
    • Boston, USA (October ) (Abstract 127)
    • MERKEL C, MARIN R, ANGELI P et al.: Beta-blockers in the prevention of aggravation of esophageal varices in patients with cirrhosis and small varices: a placebocontrolled clinical trial. Proceedings of the annual meeting of the American Association for the Study of the Liver (AASLD), Boston, USA (October 2003) (Abstract 127).
    • (2003) Proceedings of the Annual Meeting of the American Association for the Study of the Liver (AASLD)
    • Merkel, C.1    Marin, R.2    Angeli, P.3
  • 13
    • 0025016059 scopus 로고
    • Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage
    • GROSZMANN RJ, BOSCH J, GRACE ND et al.: Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Gastroenterology (1990) 99:1401-1407.
    • (1990) Gastroenterology , vol.99 , pp. 1401-1407
    • Groszmann, R.J.1    Bosch, J.2    Grace, N.D.3
  • 14
    • 0028790232 scopus 로고
    • Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis
    • FEU F, GARCIA-PAGAN JC, BOSCH J et al.: Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis. Lancet (1995) 346:1056-1059.
    • (1995) Lancet , vol.346 , pp. 1056-1059
    • Feu, F.1    Garcia-Pagan, J.C.2    Bosch, J.3
  • 15
    • 0025243721 scopus 로고
    • Long-term haemodynamic effects of isosorbide 5-mononitrate in patients with cirrhosis and portal hypertension
    • GARCIA-PAGAN JC, FEU F, NAVASA M et al.: Long-term haemodynamic effects of isosorbide 5-mononitrate in patients with cirrhosis and portal hypertension. J. Hepatol. (1990) 11:189-195.
    • (1990) J. Hepatol. , vol.11 , pp. 189-195
    • Garcia-Pagan, J.C.1    Feu, F.2    Navasa, M.3
  • 16
    • 0027988534 scopus 로고
    • Propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis: Long-term hemodynamic and renal effects
    • MORILLAS RM, PLANAS R, CABRE E, GALAN A, QUER JC, FEU F et al.: Propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis: long-term hemodynamic and renal effects. Hepatology (1994) 20:1502-1508.
    • (1994) Hepatology , vol.20 , pp. 1502-1508
    • Morillas, R.M.1    Planas, R.2    Cabre, E.3    Galan, A.4    Quer, J.C.5    Feu, F.6
  • 17
    • 0026595277 scopus 로고
    • Oral administration of clonidine in patients with alcoholic cirrhosis: Hemodynamic and liver function effects
    • ALBILLOS A, BANARES R, BARRIOS C et al.: Oral administration of clonidine in patients with alcoholic cirrhosis: Hemodynamic and liver function effects. Gastroenterology (1992) 102:248-254.
    • (1992) Gastroenterology , vol.102 , pp. 248-254
    • Albillos, A.1    Banares, R.2    Barrios, C.3
  • 18
    • 0019475917 scopus 로고
    • Propranolol in prevention of recurrent gastrointestinal bleeding in cirrhotic patients
    • LEBREC D, NOUEL O, BERNUAU J, BOUIGUES M, RUEFF B, BENHAMOU JP: Propranolol in prevention of recurrent gastrointestinal bleeding in cirrhotic patients. Lancet (1981) 1:920-921.
    • (1981) Lancet , vol.1 , pp. 920-921
    • Lebrec, D.1    Nouel, O.2    Bernuau, J.3    Bouigues, M.4    Rueff, B.5    Benhamou, J.P.6
  • 19
    • 0020449643 scopus 로고
    • The effect of propranolol on portal hypertension in patients with cirrhosis: A hemodynamic study
    • LEBREC D, HILLON P, MUNOZ C, GOLDFARB G, NOUEL O, BENHAMOU JP: The effect of propranolol on portal hypertension in patients with cirrhosis: a hemodynamic study. Hepatology (1982) 2:523-527.
    • (1982) Hepatology , vol.2 , pp. 523-527
    • Lebrec, D.1    Hillon, P.2    Munoz, C.3    Goldfarb, G.4    Nouel, O.5    Benhamou, J.P.6
  • 20
    • 0021750470 scopus 로고
    • Effects of propranolol on azygos venous blood flow and hepatic and systemic hemodynamics in cirrhosis
    • BOSCH J, MASTAI R, KRAVETZ Der et al.: Effects of propranolol on azygos venous blood flow and hepatic and systemic hemodynamics in cirrhosis. Hepatology (1984) 4:1200-1205.
    • (1984) Hepatology , vol.4 , pp. 1200-1205
    • Bosch, J.1    Mastai, R.2    Kravetz, D.3
  • 21
    • 0022632991 scopus 로고
    • Short-term effects of propranolol on portal venous pressure
    • GARCIA-TSAO, G, GRACE ND, GROSZMANN RJ et al.: Short-term effects of propranolol on portal venous pressure. Hepatology (1986) 6:101-106.
    • (1986) Hepatology , vol.6 , pp. 101-106
    • Garcia-Tsao, G.1    Grace, N.D.2    Groszmann, R.J.3
  • 22
    • 0031003291 scopus 로고    scopus 로고
    • The portal pressure response to beta-blockade is greater in cirrhotic patients without varices than in those with varices
    • ESCORSELL A, FERAYORNI L, BOSCH J et al.: The portal pressure response to beta-blockade is greater in cirrhotic patients without varices than in those with varices. Gastroenterology (1997) 112:2012-2016.
    • (1997) Gastroenterology , vol.112 , pp. 2012-2016
    • Escorsell, A.1    Ferayorni, L.2    Bosch, J.3
  • 23
    • 0023778102 scopus 로고
    • Effects of vasopressin on the intravariceal pressure in patients with cirrhosis: Comparison with the effects on portal pressure
    • BOSCH J, BORDAS JM, MASTAI R et al.: Effects of vasopressin on the intravariceal pressure in patients with cirrhosis: comparison with the effects on portal pressure: Hepatology (1988) 8:861-865.
    • (1988) Hepatology , vol.8 , pp. 861-865
    • Bosch, J.1    Bordas, J.M.2    Mastai, R.3
  • 24
    • 0024808397 scopus 로고
    • Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: A placebo-controlled clinical trial
    • BOSCH J, GROSZMANN RJ, GARCIA-PAGAN JC et al.: Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: a placebo-controlled clinical trial. Hepatology (1989) 10:962-968.
    • (1989) Hepatology , vol.10 , pp. 962-968
    • Bosch, J.1    Groszmann, R.J.2    Garcia-Pagan, J.C.3
  • 25
    • 0031618979 scopus 로고    scopus 로고
    • Development of analogues: Successes and failures
    • BOSCH J, LEBREC D, JENKINS SA: Development of analogues: successes and failures. Scand J. Gastroenterol. (1998) 226(Suppl.):3-13.
    • (1998) Scand. J. Gastroenterol. , vol.226 , Issue.SUPPL. , pp. 3-13
    • Bosch, J.1    Lebrec, D.2    Jenkins, S.A.3
  • 26
    • 0023764042 scopus 로고
    • Effects of somatostatin in patients with portal hypertension
    • BOSCH J, KRAVETZ D, MASTAI R et al.: Effects of somatostatin in patients with portal hypertension. Horm. Res. (1988) 29:99-102.
    • (1988) Horm. Res. , vol.29 , pp. 99-102
    • Bosch, J.1    Kravetz, D.2    Mastai, R.3
  • 27
    • 0029097260 scopus 로고
    • Effects of bolus injections and continuous infusions of somatostatin and placebo in patients with cirrhosis: A double-blind hemodynamic investigation
    • CIRERA I, FEU F, LUCA A, GARCIA-PAGAN JC et al.: Effects of bolus injections and continuous infusions of somatostatin and placebo in patients with cirrhosis: a double-blind hemodynamic investigation. Hepatology (1995) 22:106-111.
    • (1995) Hepatology , vol.22 , pp. 106-111
    • Cirera, I.1    Feu, F.2    Luca, A.3    Garcia-Pagan, J.C.4
  • 28
    • 0035743114 scopus 로고    scopus 로고
    • Multicenter randomized controlled trial comparing different schedules of somatostatin in the treatment of acute variceal bleeding
    • MOITINHO E, PLANAS R, BANARES R et al.: Multicenter randomized controlled trial comparing different schedules of somatostatin in the treatment of acute variceal bleeding. J. Hepatol. (2001) 35:712-718.
    • (2001) J. Hepatol. , vol.35 , pp. 712-718
    • Moitinho, E.1    Planas, R.2    Banares, R.3
  • 29
    • 0035165156 scopus 로고    scopus 로고
    • Desensitization to the effects of intravenous Octreotide in cirrhotic patients with portal hypertension
    • ESCORSELL A, BANDI JC, ANDREU V et al.: Desensitization to the effects of intravenous Octreotide in cirrhotic patients with portal hypertension. Gastroenterology (2001) 120:161-169.
    • (2001) Gastroenterology , vol.120 , pp. 161-169
    • Escorsell, A.1    Bandi, J.C.2    Andreu, V.3
  • 30
    • 0034006836 scopus 로고    scopus 로고
    • 48-hour hemodynamic effects of octreotide on postprandial splanchnic hyperemia in patients with liver cirrhosis and portal hypertension: Double-blind, placebo-controlled study
    • LUDWIG D, SCHADEL S, BRUNING A, SCHIEFER B, STANGE EF: 48-hour hemodynamic effects of octreotide on postprandial splanchnic hyperemia in patients with liver cirrhosis and portal hypertension: double-blind, placebo-controlled study. Dig. Dis. Sci. (2000) 45:1019-1027.
    • (2000) Dig. Dis. Sci. , vol.45 , pp. 1019-1027
    • Ludwig, D.1    Schadel, S.2    Bruning, A.3    Schiefer, B.4    Stange, E.F.5
  • 31
    • 0025906655 scopus 로고
    • Propranolol compared with propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis. A randomized controlled study
    • GARCIA-PAGAN JC, FEU F, BOSCH J, RODES J: Propranolol compared with propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis. A randomized controlled study. Ann. Intern. Med. (1991) 114:869-873.
    • (1991) Ann. Intern. Med. , vol.114 , pp. 869-873
    • Garcia-Pagan, J.C.1    Feu, F.2    Bosch, J.3    Rodes, J.4
  • 32
    • 17544385944 scopus 로고    scopus 로고
    • Propranolot plus prazosin compared with propranolol plus isosorbide-5-mononitrate in the treatment of portal hypertension
    • ALBILLOS A, GARCIA-PAGAN JC, IBORRA J et al.: Propranolot plus prazosin compared with propranolol plus isosorbide-5-mononitrate in the treatment of portal hypertension. Gastroenterology (1998) 115:116-123.
    • (1998) Gastroenterology , vol.115 , pp. 116-123
    • Albillos, A.1    Garcia-Pagan, J.C.2    Iborra, J.3
  • 33
    • 0035188533 scopus 로고    scopus 로고
    • Propranolol for the prevention of first esophageal variceal hemorrhage: A lifetime commitment?
    • ABRACZINSKAS DR, OOKUBO R, GRACE ND et al.: Propranolol for the prevention of first esophageal variceal hemorrhage: a lifetime commitment? Hepatology (2001) 34:1096-1102.
    • (2001) Hepatology , vol.34 , pp. 1096-1102
    • Abraczinskas, D.R.1    Ookubo, R.2    Grace, N.D.3
  • 34
    • 0037309643 scopus 로고    scopus 로고
    • Endoscopic screening for esophageal varices in cirrhosis: Is it ever cost effective?
    • SPIEGEL B, TARGOWNIK L, DULAI GS, KARSAN HA, GRALNEK IM: Endoscopic screening for esophageal varices in cirrhosis: is it ever cost effective? Hepatology (2003) 37:366-377.
    • (2003) Hepatology , vol.37 , pp. 366-377
    • Spiegel, B.1    Targownik, L.2    Dulai, G.S.3    Karsan, H.A.4    Gralnek, I.M.5
  • 35
    • 0034792003 scopus 로고    scopus 로고
    • Isosorbide mononitrate in the prevention of first variceal bleed in patients who cannot receive β-blockers
    • GARCIA-PAGAN JC, VILLANUEVA C, VILA MC et al.: Isosorbide mononitrate in the prevention of first variceal bleed in patients who cannot receive β-blockers. Gastroenterology (2001) 121:908-914.
    • (2001) Gastroenterology , vol.121 , pp. 908-914
    • Garcia-pagan, J.C.1    Villanueva, C.2    Vila, M.C.3
  • 36
    • 0342980277 scopus 로고    scopus 로고
    • Influence of pharmacological agents on portal hemodynamics: Basis for its use in the treatment of portal hypertension
    • GARCIA-PAGAN JC, ESCORSELL A, MOITINHO E, BOSCH J: Influence of pharmacological agents on portal hemodynamics: basis for its use in the treatment of portal hypertension. Semin. Liver Dis. (1999) 19:427-438.
    • (1999) Semin. Liver Dis. , vol.19 , pp. 427-438
    • Garcia-Pagan, J.C.1    Escorsell, A.2    Moitinho, E.3    Bosch, J.4
  • 37
  • 38
    • 0035083039 scopus 로고    scopus 로고
    • A meta-analysis of endoscopic variceal ligation for primary prophylaxis of variceal bleeding
    • IMPERIALE T, CHALASANI N: A meta-analysis of endoscopic variceal ligation for primary prophylaxis of variceal bleeding. Hepatology (2001) 33:802-807.
    • (2001) Hepatology , vol.33 , pp. 802-807
    • Imperiale, T.1    Chalasani, N.2
  • 39
    • 0036731212 scopus 로고    scopus 로고
    • Primary prophylaxis of variceal hemorrhage. A randomised controlled trial comparing band ligation, propranolol and isosorbide mononitrate
    • LUI HF, STANLEY AJ, FORREST HE, JALAN R, HISLOP WS, MILLS PR: Primary prophylaxis of variceal hemorrhage. A randomised controlled trial comparing band ligation, propranolol and isosorbide mononitrate. Gastroenterology (2002) 132:735-744.
    • (2002) Gastroenterology , vol.132 , pp. 735-744
    • Lui, H.F.1    Stanley, A.J.2    Forrest, H.E.3    Jalan, R.4    Hislop, W.S.5    Mills, P.R.6
  • 40
    • 0002019774 scopus 로고    scopus 로고
    • A prospective randomised trial between the prophylactic endoscopic variceal ligation and propranolol administration for prevention of first bleeding in cirrhotic patients with high risk esophageal varices
    • SONG HI, SHIN JW, KIM IH: A prospective randomised trial between the prophylactic endoscopic variceal ligation and propranolol administration for prevention of first bleeding in cirrhotic patients with high risk esophageal varices. J. Hepatol. (2002) 32(Suppl. 2):41.
    • (2002) J. Hepatol. , vol.32 , Issue.SUPPL. 2 , pp. 41
    • Song, H.I.1    Shin, J.W.2    Kim, I.H.3
  • 42
    • 0033118990 scopus 로고    scopus 로고
    • Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding
    • SARIN SK, LAMBA GS, KUMAR M, MISRA A, MURTHY NS: Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding. N. Engl. J. Med. 1999 340:988-993.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 988-993
    • Sarin, S.K.1    Lamba, G.S.2    Kumar, M.3    Misra, A.4    Murthy, N.S.5
  • 46
    • 0037265143 scopus 로고    scopus 로고
    • Terlipressin for acute esophageal variceal hemorrhage
    • (Cochrane Review). Update Software, Oxford
    • IOANNOU G, DOUST J, ROCKEY DC: Terlipressin for acute esophageal variceal hemorrhage (Cochrane Review). In: The Cochrane Library Issue 3, Update Software, Oxford (2003).
    • (2003) The Cochrane Library Issue 3
    • Ioannou, G.1    Doust, J.2    Rockey, D.C.3
  • 47
    • 0029164414 scopus 로고
    • A meta-analysis of somatostatin versus vasopressin in the management of acute esophageal variceal hemorrhage
    • IMPERIALE TF, TERAN JC, MCCULLOUGH AJ: A meta-analysis of somatostatin versus vasopressin in the management of acute esophageal variceal hemorrhage. Gastroenterology (1995) 109:1289-1294.
    • (1995) Gastroenterology , vol.109 , pp. 1289-1294
    • Imperiale, T.F.1    Teran, J.C.2    McCullough, A.J.3
  • 49
    • 0000623981 scopus 로고    scopus 로고
    • Double blind RCT of 5 day octreotide versus placebo, associated with sclerotherapy for trial failures
    • BURROUGHS AK: Double blind RCT of 5 day octreotide versus placebo, associated with sclerotherapy for trial failures. Hepatology (1996) 24:352A.
    • (1996) Hepatology , vol.24
    • Burroughs, A.K.1
  • 50
    • 0038297513 scopus 로고    scopus 로고
    • Emergency sclerotherapy versus vasoactive drugs for variceal bleeding in cirrhosis: A Cochrane meta-analysis
    • D'AMICO G, PIETROSI G, TARANTINO I, PAGLIAR0 L: Emergency sclerotherapy versus vasoactive drugs for variceal bleeding in cirrhosis: a Cochrane meta-analysis. Gastroenterology (2003) 124:1277-1291.
    • (2003) Gastroenterology , vol.124 , pp. 1277-1291
    • D'Amico, G.1    Pietrosi, G.2    Tarantino, I.3    Pagliaro, L.4
  • 51
    • 0036192233 scopus 로고    scopus 로고
    • Endoscopic treatment versus endoscopic plus pharmacologic treatment for acute variceal bleeding: A meta-analysis
    • BANARES R, ALBILLOS A, RINCON D et al.: Endoscopic treatment versus endoscopic plus pharmacologic treatment for acute variceal bleeding: a meta-analysis. Hepatology (2002) 35:609-615.
    • (2002) Hepatology , vol.35 , pp. 609-615
    • Banares, R.1    Albillos, A.2    Rincon, D.3
  • 52
    • 0033757767 scopus 로고    scopus 로고
    • Updating consensus in portal hypertension: Report of the Baveno III consensus workshop on definitions, methodology and therapeutic strategies in portal hypertension
    • DE FRANCHIS R: Updating consensus in portal hypertension: report of the Baveno III consensus workshop on definitions, methodology and therapeutic strategies in portal hypertension. J. Hepatol. (2000) 33:846-852.
    • (2000) J. Hepatol. , vol.33 , pp. 846-852
    • De Franchis, R.1
  • 53
    • 0031030010 scopus 로고    scopus 로고
    • Beta-adrenergic antagonists in the prevention of gastrointestinal rebleeding in patients with cirrhosis: A meta-analysis
    • BERNARD B, LEBREC D, MATHURIN P, OPOLON P, POYNARD T: Beta-adrenergic antagonists in the prevention of gastrointestinal rebleeding in patients with cirrhosis: a meta-analysis. Hepatology (1997) 25:63-70.
    • (1997) Hepatology , vol.25 , pp. 63-70
    • Bernard, B.1    Lebrec, D.2    Mathurin, P.3    Opolon, P.4    Poynard, T.5
  • 54
    • 0034074123 scopus 로고    scopus 로고
    • Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding
    • GOURNAY J, MASLIAH C, MARTIN T, PERRIN D, GALMICHE JP: Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding. Hepatology (2000) 31:1239-1245.
    • (2000) Hepatology , vol.31 , pp. 1239-1245
    • Gournay, J.1    Masliah, C.2    Martin, T.3    Perrin, D.4    Galmiche, J.P.5
  • 55
    • 0012052303 scopus 로고    scopus 로고
    • Isosorbide mononitrate with nadolol compared to nadolol alone for prevention of recurrent bleeding in cirrhosis. A double blind placebo controlled randomized trial. Final report
    • PATTI R, PASTA L, D'AMICO G: Isosorbide mononitrate with nadolol compared to nadolol alone for prevention of recurrent bleeding in cirrhosis. A double blind placebo controlled randomized trial. Final report. J. Hepatol. (2001) 34:64.
    • (2001) J. Hepatol. , vol.34 , pp. 64
    • Patti, R.1    Pasta, L.2    D'Amico, G.3
  • 56
    • 0030003919 scopus 로고    scopus 로고
    • Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal bleeding
    • VILLANUEVA C, BALANZÒ J, NOVELLA M et al.: Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal bleeding. N. Engl. J. Med. (1996) 334:1624.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1624
    • Villanueva, C.1    Balanzò, J.2    Novella, M.3
  • 57
    • 0035975395 scopus 로고    scopus 로고
    • Endoscopic ligation compared with combined treatment with nadolol and isosorbide mononitrate to prevent recurrent variceal bleeding
    • VILLANUEVA C, MINANA J, ORTIZ J, GALLEGO A, SORIANO G, TORRAS X et al. Endoscopic ligation compared with combined treatment with nadolol and isosorbide mononitrate to prevent recurrent variceal bleeding: N. Engl. J. Med. (2001) 345:647-655.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 647-655
    • Villanueva, C.1    Minana, J.2    Ortiz, J.3    Gallego, A.4    Soriano, G.5    Torras, X.6
  • 58
    • 0036788252 scopus 로고    scopus 로고
    • A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis
    • PATCH D, SABIN CA, GOULIS J et al.: A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis. Gastroenterology (2002) 123:1013-1019.
    • (2002) Gastroenterology , vol.123 , pp. 1013-1019
    • Patch, D.1    Sabin, C.A.2    Goulis, J.3
  • 59
    • 0036731118 scopus 로고    scopus 로고
    • Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal rebleeding
    • LO GH, CHEN WC, CHEN MH et al.: Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal rebleeding: Gastroenterology (2002) 123:728-734.
    • (2002) Gastroenterology , vol.123 , pp. 728-734
    • Lo, G.H.1    Chen, W.C.2    Chen, M.H.3
  • 60
    • 18244380855 scopus 로고    scopus 로고
    • TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: A randomized controlled trial
    • ESCORSELL A, BANARES R, GARCIA-PAGAN JC et al.: TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: a randomized controlled trial. Hepatology (2002) 35:385-392.
    • (2002) Hepatology , vol.35 , pp. 385-392
    • Escorsell, A.1    Banares, R.2    Garcia-Pagan, J.C.3
  • 61
    • 0032923849 scopus 로고    scopus 로고
    • The economic impact of esophageal variceal hemorrhage: Cost-effectiveness implications of endoscopic therapy
    • GRALNEK IM, JENSEN DM, KOVACS TOG et al.: The economic impact of esophageal variceal hemorrhage: cost-effectiveness implications of endoscopic therapy. Hepatology (1999) 29:44-50.
    • (1999) Hepatology , vol.29 , pp. 44-50
    • Gralnek, I.M.1    Jensen, D.M.2    Kovacs, T.O.G.3
  • 62
    • 17544362526 scopus 로고    scopus 로고
    • Long term results of a clinical trial of nadolol with or without isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis
    • MERKEL C, MARIN R, SACERDOTI D et al.: Long term results of a clinical trial of nadolol with or without isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis. Hepatology (2000) 31:324-329.
    • (2000) Hepatology , vol.31 , pp. 324-329
    • Merkel, C.1    Marin, R.2    Sacerdoti, D.3
  • 63
    • 0036896603 scopus 로고    scopus 로고
    • "A la carte" treatment of portal hypertension: Adapting medical therapy to hemodynamic response for the prevention of bleeding
    • BUREAU C, PERON JM, ALRIC L et al.: "A la carte" treatment of portal hypertension: adapting medical therapy to hemodynamic response for the prevention of bleeding. Hepatology (2002) 36:1361-1366.
    • (2002) Hepatology , vol.36 , pp. 1361-1366
    • Bureau, C.1    Peron, J.M.2    Alric, L.3
  • 64
    • 0037382804 scopus 로고    scopus 로고
    • Hemodynamic response to pharmacologic treatment of portal hypertension and long term prognosis of cirrhosis
    • ABRALDES J, TARANTINO I, TURNES J, GARCIA-PAGAN JC, RODES J, BOSCH J: Hemodynamic response to pharmacologic treatment of portal hypertension and long term prognosis of cirrhosis. Hepatology (2003) 37:902-908.
    • (2003) Hepatology , vol.37 , pp. 902-908
    • Abraldes, J.1    Tarantino, I.2    Turnes, J.3    Garcia-Pagan, J.C.4    Rodes, J.5    Bosch, J.6
  • 65
    • 0029088488 scopus 로고
    • Continuous prazosin administration in cirrhotic patients: Effects on portal hemodynamics and on liver and renal function
    • ALBILLOS A, LLEDO JL, ROSSI I et al.: Continuous prazosin administration in cirrhotic patients: effects on portal hemodynamics and on liver and renal function. Gastroenterology (1995) 109:1257-1265.
    • (1995) Gastroenterology , vol.109 , pp. 1257-1265
    • Albillos, A.1    Lledo, J.L.2    Rossi, I.3
  • 67
    • 0032988091 scopus 로고    scopus 로고
    • Effect of losartan, an angiotensin II receptor antagonist, on portal pressure in cirrhosis
    • SCHNEIDER AW, FRIEDRICH J, KLEIN CP: Effect of losartan, an angiotensin II receptor antagonist, on portal pressure in cirrhosis. Hepatology (1999) 29:334-339.
    • (1999) Hepatology , vol.29 , pp. 334-339
    • Schneider, A.W.1    Friedrich, J.2    Klein, C.P.3
  • 68
    • 0037386111 scopus 로고    scopus 로고
    • Effects of long-term Irbesartan in reducing portal pressure in cirrhotic patients: Comparison with propranolol in a randomised controlled study
    • DEBERNARDI VENON W, BARONIO M et al.: Effects of long-term Irbesartan in reducing portal pressure in cirrhotic patients: comparison with propranolol in a randomised controlled study. J. Hepatol. (2003) 38:455-460.
    • (2003) J. Hepatol. , vol.38 , pp. 455-460
    • Debernardi Venon, W.1    Baronio, M.2
  • 69
    • 0034961836 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis
    • JONSSON JR, CLOUSTON AD, ANDO Y et al.: Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis. Gastroenterology (2001) 121:148-155.
    • (2001) Gastroenterology , vol.121 , pp. 148-155
    • Jonsson, J.R.1    Clouston, A.D.2    Ando, Y.3
  • 70
    • 0012236876 scopus 로고    scopus 로고
    • The effect of endothelin and its antagonist Bosentan on hemodynamics and microvascular exchange in cirrhotic rat liver
    • REICHEN J, GERBES AL, STEINER MJ, SAGESSER H, CLOZEL M: The effect of endothelin and its antagonist Bosentan on hemodynamics and microvascular exchange in cirrhotic rat liver. J. Hepatol. (1998) 28:1020-1030.
    • (1998) J. Hepatol. , vol.28 , pp. 1020-1030
    • Reichen, J.1    Gerbes, A.L.2    Steiner, M.J.3    Sagesser, H.4    Clozel, M.5
  • 71
    • 0032899947 scopus 로고    scopus 로고
    • Chronic blockade of endothelin receptors in cirrhotic rats: Hepatic and hemodynamic effects
    • POO JL, JIMENEZ W, MARIA MUNOZ R et al.: Chronic blockade of endothelin receptors in cirrhotic rats: hepatic and hemodynamic effects. Gastroenterology (1999) 116:161-167.
    • (1999) Gastroenterology , vol.116 , pp. 161-167
    • Poo, J.L.1    Jimenez, W.2    Maria Munoz, R.3
  • 72
    • 0034120477 scopus 로고    scopus 로고
    • An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis
    • CHO JJ, HOCHER B, HERBST H et al.: An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. Gastroenterology (2000) 118:1169-1178.
    • (2000) Gastroenterology , vol.118 , pp. 1169-1178
    • Cho, J.J.1    Hocher, B.2    Herbst, H.3
  • 73
    • 0034958165 scopus 로고    scopus 로고
    • Endothelin-1 plays a major role in portal hypertension of biliary cirrhotic rats through endothelin receptor subtype B together with subtype A in vivo
    • KOJIMA H, SAKURAI S, KURIYAMA S et al.: Endothelin-1 plays a major role in portal hypertension of biliary cirrhotic rats through endothelin receptor subtype B together with subtype A in vivo. J. Hepatol. (2001) 34:805-811.
    • (2001) J. Hepatol. , vol.34 , pp. 805-811
    • Kojima, H.1    Sakurai, S.2    Kuriyama, S.3
  • 74
    • 0027234674 scopus 로고
    • Nipradilol, a new beta-blocker with vasodilatory properties, in experimental portal hypertension: A comparative haemodynamic study with propranolol
    • UM S, NISHIDA O, TOKUBAYASHI M, KIMURAF, KITA T: Nipradilol, a new beta-blocker with vasodilatory properties, in experimental portal hypertension: a comparative haemodynamic study with propranolol. J. Gastroenterol. Hepatol. (1993) 8:414-419.
    • (1993) J. Gastroenterol. Hepatol. , vol.8 , pp. 414-419
    • Um, S.1    Nishida, O.2    Tokubayashi, M.3    Kimuraf, A.4    Kita, T.5
  • 75
    • 0026752438 scopus 로고
    • Long-term haemodynamic effects of a 4-week regimen of nipradilol, a new beta-blocker with nitrovasodilating properties, in patients with portal hypertension due to cirrhosis. A comparative study with propranolol
    • ARAMAKI T, SEKIYAMA T, KATSUTA Y et al.: Long-term haemodynamic effects of a 4-week regimen of nipradilol, a new beta-blocker with nitrovasodilating properties, in patients with portal hypertension due to cirrhosis. A comparative study with propranolol. J. Hepatol. (1992) 15:48-53.
    • (1992) J. Hepatol. , vol.15 , pp. 48-53
    • Aramaki, T.1    Sekiyama, T.2    Katsuta, Y.3
  • 76
    • 0033000308 scopus 로고    scopus 로고
    • 1-adrenergic activity, has a greater portal hypotensive effect than propranolol in patients with cirrhosis
    • 1-adrenergic activity, has a greater portal hypotensive effect than propranolol in patients with cirrhosis. Hepatology (1999) 30:79-83.
    • (1999) Hepatology , vol.30 , pp. 79-83
    • Bańares, R.1    Moitinho, E.2    Piqueras, B.3
  • 77
    • 0033040460 scopus 로고    scopus 로고
    • Acute and chronic haemodynamic and renal effects of carvedilol in patients with cirrhosis
    • STANLEY AJ, THERAPONDOS G, HELMY A, HAYES PC: Acute and chronic haemodynamic and renal effects of carvedilol in patients with cirrhosis. J. Hepatol. (1999) 30:479-484.
    • (1999) J. Hepatol. , vol.30 , pp. 479-484
    • Stanley, A.J.1    Therapondos, G.2    Helmy, A.3    Hayes, P.C.4
  • 78
    • 0036185720 scopus 로고    scopus 로고
    • Haemodynamic effects of acute and chronic administration of low-dose carvedilol, a vasodilating beta-blocker, in patients with cirrhosis and portal hypertension
    • TRIPATHI D, THERAPONDOS G, LUI HF, STANLEY AJ, HAYES PC: Haemodynamic effects of acute and chronic administration of low-dose carvedilol, a vasodilating beta-blocker, in patients with cirrhosis and portal hypertension. Aliment. Pharmacol. Ther. (2002) 16:373-380.
    • (2002) Aliment. Pharmacol. Ther. , vol.16 , pp. 373-380
    • Tripathi, D.1    Therapondos, G.2    Lui, H.F.3    Stanley, A.J.4    Hayes, P.C.5
  • 79
    • 0036894514 scopus 로고    scopus 로고
    • Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis
    • BANARES R, MOITINHO E, MATILLA A et al.: Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis. Hepatology (2002) 36:1367-1373.
    • (2002) Hepatology , vol.36 , pp. 1367-1373
    • Banares, R.1    Moitinho, E.2    Matilla, A.3
  • 80
    • 0000411955 scopus 로고    scopus 로고
    • Crhonic antifibrotic and hemodynamic effects of a new liver specific NO donor (V-pyrro/NO) in bile duct ligated (BDL) rats
    • MOAL F, VUILLEMIN E, WANG J: Crhonic antifibrotic and hemodynamic effects of a new liver specific NO donor (V-pyrro/NO) in bile duct ligated (BDL) rats. Hepatology (2001) 32:186A.
    • (2001) Hepatology , vol.32
    • Moal, F.1    Vuillemin, E.2    Wang, J.3
  • 81
    • 0035902558 scopus 로고    scopus 로고
    • NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension
    • FIORUCCI S, ANTONELLI E, MORELLI O etal.: NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension. Proc. Natl. Acad. Sci. USA (2001) 98:8897-8902.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 8897-8902
    • Fiorucci, S.1    Antonelli, E.2    Morelli, O.3
  • 82
    • 0029080383 scopus 로고
    • The effect of nitric oxide synthase inhibition on portal pressure and azygos blood flow in patients with cirrhosis
    • FORREST EH, JONES AL, DILLON JF, WALKER J, HAYES PC: The effect of nitric oxide synthase inhibition on portal pressure and azygos blood flow in patients with cirrhosis. J. Hepatol. (1995) 23:254-258.
    • (1995) J. Hepatol. , vol.23 , pp. 254-258
    • Forrest, E.H.1    Jones, A.L.2    Dillon, J.F.3    Walker, J.4    Hayes, P.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.