Alkalimetry in alcohol-water mixtures with potentiometric end-point detection: Critical remarks on a newer method of European Pharmacopoeia

Analytica Chimica Acta

Volumn 507, Issue 2, 2004, Pages 275-280

  Takács Novák, Krisztina ^a   Völgyi, Gergely ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Alkalimetry; Ph. Eur. assay; pKa determination; Potentiometric titration

Indexed keywords

ASSAYS; HYDROCHLORIC ACID; PH EFFECTS; SALTS; TITRATION;

INFLEXION POINT; POTENTIOMETRIC END-POINT DETECTION;

ALCOHOLS;

ALCOHOL; ALKALOID; BASE; HALIDE; HISTAMINE; HYDROCHLORIC ACID; NOSCAPINE; PAPAVERINE; PILOCARPINE; PYRIDOXINE; THIAMINE; WATER;

ALKALIMETRY; ANALYTIC METHOD; ARTICLE; DRUG DETERMINATION; EUROPE; MEDICAL LITERATURE; POTENTIOMETRY; PRIORITY JOURNAL; REPRODUCIBILITY; TITRIMETRY;

EID: 1242306206     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2003.11.049     Document Type: Article

References (12)

1. European Pharmacopoeia, third ed., Council of Europe, Strasbourg, 1997.
2. European Pharmacopoeia, fourth ed., Council of Europe, Strasbourg, 2002.
3. Deutsches Arzneibuch, Deutscher Apotheker-verlag, seventh ed., Stuttgart, 1968.
4. Bye R. Sci. Pharm. 70:2002;129.
5. Takács-Novák K., Avdeef A., Box K.J., Podányi B., Szász Gy. J. Pharm. Biomed. Anal. 12:1994;1369.
6. Takács-Novák K., Avdeef A. J. Pharm. Biomed. Anal. 14:1996;1405.
7. Takács-Novák K., Box K.J., Avdeef A. Int. J. Pharm. 151:1997;235.
8. Tam K.Y., Takács-Novák K. Anal. Chim. Acta. 434:2001;157.
9. K.A. Connors, A textbook of Pharmaceutical Analysis, Wiley, New York, 1967.
10. Avdeef A., Comer J.E.A., Thomson S.J. Anal. Chem. 65:1993;42.
11. Rosés M., Ráfols C., Bosch E. Anal. Chem. 65:1993;2294.
12. a values for some drugs and miscellaneous organic acids and bases, in: D.A. Williams, T.L. Lemke (Eds.), Foye's Principles of Medicinal Chemistry, fifth ed., Lippincot W. & W., New York, 2002, p. 1070.