Caldesmon Phosphorylation Is Catalyzed by Two Kinases in Permeabilized and Intact Vascular Smooth Muscle

Journal of Cellular Physiology

Volumn 198, Issue 3, 2004, Pages 461-469

  Gorenne, Isabelle ^a,b   Su, Xiaoling ^a   Moreland, Robert S ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ADENOSINE TRIPHOSPHATE; CALCIUM ION; CALDESMON; CALDESMON KINASE; CALMODULIN BINDING PROTEIN; EGTAZIC ACID; ENZYME INHIBITOR; FLAVONOID; HISTAMINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN KINASE; OCTOXINOL; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN P42; PROTEIN P44; STAUROSPORINE; TRITON X 100; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAROTID ARTERY; CATALYSIS; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; ENZYME MECHANISM; HISTAMINE RELEASE; INHIBITION KINETICS; MEMBRANE PERMEABILITY; METABOLISM; MUSCLE CONTRACTION; NONHUMAN; PHOSPHORYLATION; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENSITIVITY ANALYSIS; SKINNED MUSCLE FIBER; SMOOTH MUSCLE CONTRACTILITY; SWINE; TWO DIMENSIONAL GEL ELECTROPHORESIS; VASCULAR SMOOTH MUSCLE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALMODULIN-BINDING PROTEINS; CATALYSIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME INHIBITORS; FLAVONOIDS; HISTAMINE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; OCTOXYNOL; PHOSPHORYLATION; STAUROSPORINE; SWINE;

SUS SCROFA;

EID: 1242294530     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10440     Document Type: Article

References (40)

1. 2+/calmodulin-dependent protein kinase II in the mitogen-activated protein kinase cascade of cultured rat aortic vascular smooth muscle. Circ Res 81:575-584.
2. Adam LP, Hathway DR. 1993. Identification of mitogen-activated protein kinase phosphorylation sequences in mammalian h-caldesmon. FEBS Lett 322:56-60.
3. Adam LP, Gapinski CJ, Hathaway DR. 1992. Phosphorylation sequences in h-caldesmon from phorbol ester stimulated canine aortas. FEBS Lett 302:223-226.
4. Albrecht K, Schneider A, Liebetrau C, Ruegg JC, Pfitzer G. 1997. Exogenous caldesmon promotes relaxation of guinea-pig skinned taenia coli smooth muscles: Inhibition of cooperative reattachment of latch bridges? Pflugers Arch 434:534-542.
5. Dessy C, Kim I, Sougnez CL, Laporte R, Morgan KG. 1998. A role for MAP kinase in differentiated smooth muscle contraction evoked by alpha-adrenoceptor stimulation. Am J Physiol 275:C1081-C1086.
6. Earley JJ, Su X, Moreland RS. 1998. Caldesmon inhibits active crossbridges in unstimulated vascular smooth muscle. An antisense oligodeoxynucleotide approach. Circ Res 83:661-667.
7. Fulginiti J, Singer HA, Moreland RS. 1993. Phorbol ester induced contractions of swine carotid artery are supported by slowly cycling crossbridges which are not dependent on calcium or myosin light chain phosphorylation. J Vasc Res 30:315-322.
8. Gerthoffer WT, Yamboliev IA, Shearer M, Pohl J, Haynes R, Dang S, Sato K, Sellers JR. 1996. Activation of MAP kinases and phosphorylation of caldesmon in canine colonic smooth muscle. J Physiol 495:597-609.
9. Gorenne I, Su X, Moreland RS. 1998. Inhibition of p42 and p44 MAP kinase activity does not alter smooth muscle contraction in swine carotid artery. Am J Physiol 275:H131-H138.
10. Hai CM, Murphy RA. 1988. Crossbridge phosphorylation and regulation of latch state in smooth muscle. Am J Physiol 254:C99-C106.
11. Hedges JC, Oxhorn BC, Carty M, Adam LP, Yambolieve IA, Gerthoffer WT. 2000. Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle. Am J Physiol 278:C718-C726.
12. Horiuchi KY, Wang Z, Chacko S. 1995. Inhibition of smooth muscle actomyosin ATPase by caldesmon is associated with caldesmon-induced conformational changes in tropomyosin bound to actin. Biochemistry 34:16815-16820.
13. Horowitz A, Menice CB, Laporte R, Morgan KG. 1996. Mechanisms of smooth muscle contraction. Physiol Rev 76:967-1003.
14. Hulvershorn J, Gallant C, Wang CA, Dessy C, Morgan KG. 2001. Calmodulin levels are dynamically regulated in living vascular smooth muscle cells. Am J Physiol 280:H1422-H1426.
15. Kameshita I, Fujisawa H. 1989. A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel. Anal Biochem 183:139-143.
16. Kamm KE, Stull JT. 1985. The function of myosin and myosin light chain kinase phosphorylation in smooth muscle. Annu Rev Pharmacol Toxicol 25:593-620.
17. Katoch SS, Moreland RS. 1995. Agonist and membrane depolarization induced activation of MAP kinase in swine carotid artery. Am J Physiol 269:H222-H229.
18. 2+- and protein kinase C-dependent stimulation of mitogen-activated protein kinase in detergent skinned vascular smooth muscle. J Cell Physiol 179:208-217.
19. Katsuyama H, Wang CL, Morgan KG. 1992. Regulation of vascular smooth muscle tone by caldesmon. J Biol Chem 267:14555-14558.
20. erk mitogen-activated protein kinase in vitro and demonstration of another caldesmon kinase in intact gizzard smooth muscle. FEBS Lett 452:254-258.
21. Li Y, Je HD, Malek S, Morgan KG. 2003. ERK1/2-mediated phosphorylation of myometrial caldesmon during pregnancy and labor. Am J Physiol 284:R192-R199.
22. Mani RS, Kay CM. 1995. Influence of caltropin on the caldesmon induced polymerization of G-actin. Biochem Biophys Res Commun 213:349-355.
23. McFawn PK, Shen L, Vincent SG, Mak A, Van Eyk JE, Fisher JT. 2003. Calcium-independent contraction and sensitisation of airway smooth muscle by p21 activated protein kinase. Am J Physiol 284: L863-L870.
24. 2+. Am J Physiol 251:C892-C903.
25. Moreland S, Moreland RS, Singer H. 1987. Apparent dissociation of myosin light chain phosphorylation and maximal velocity of shortening in KCl depolarized swine carotid artery: Effects of temperature and [KCl]. Pflügers Arch 408:139-145.
26. Morgan KG, Gangopadhyay SS. 2001. Invited review: Cross-bridge regulation by thin filament-associated proteins. J App] Physiol 91:953-962.
27. Murphy RA. 1994. What is special about smooth muscle? The significance of covalent crossbridge regulation. FASEB J 8:311-318.
28. Ngai PK, Walsh MP. 1985. Properties of caldesmon isolated from chicken gizzard. Biochem J 230:695-707.
29. 2+. J Physiol 487:283-289.
30. 2+-regulated smooth muscle thin filaments: Evidence for a structurally altered form of calmodulin. J Muscle Res Cell Motil 21:537-549.
31. Rembold CM, Murphy RA. 1986. Myoplasmic calcium, myosin phosphorylation, and regulation of the cross bridge cycle in swine arterial smooth muscle. Circ Res 58:803-815.
32. Somlyo AP, Somlyo AV. 2000. Signal transduction by G-proteins, rho-kinase, and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol 522:177-185.
33. 2+-independent vascular smooth muscle contraction. J Surg Res 78:48-53.
34. 2+-independent contraction of smooth muscle. J Biol Chem 273:23433-23439.
35. 2+-independent contractions of vascular smooth muscle. Biochem Cell Biol 74:485-502.
36. Wang CL. 2001. Caldesmon and smooth-muscle regulation. Cell Biochem Biophys 35:275-288.
37. Watts SW. 1996. Serotonin activates the mitogen-activated protein kinase pathway in vascular smooth muscle: Use of the mitogen activated protein kinase kinase inhibitor PD098059. J Pharmacol Exp Ther 279:1541-1550.
38. Zeng Q, Lagunoff D, Masaracchia R, Goeckeler Z, Cote G, Wysolmerski R. 2000. Endothelial cell retraction is induced by PAK2 monophosphorylation of myosin II. J Cell Sci 113:471-482.
39. 2+-dependent actin-activated myosin ATPase activity in detergent-skinned vascular smooth muscle. Am J Physiol 267:H1032-H1039.
40. Zhang Y, Moreland S, Moreland RS. 1994. Regulation of vascular smooth muscle contraction: Myosin light chain phosphorylation dependent and independent pathways. Can J Physiol Pharmacol 72:1386-1391.