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27
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85039573654
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note
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The reaction shown in eq 1 is a formal 1,3-addition of N-H to a triple bond involving the shift of one proton similar to known allylic amination reactions.
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28
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85039576984
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note
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The starting material 1d was recovered in ca. 40% yield.
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30
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85039576540
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note
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Efforts to determine the ee of 2e were undertaken using GC with different chiral columns. However, no satisfactory separation of enantiomers could be obtained.
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31
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85039568554
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note
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The synthesis of seven-membered rings was not achieved under these conditions.
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32
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0025071518
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Armstrong, D. W.; Li, W.; Stacup, A. M.; Secor, H. V.; Izac, R. R.; Seeman, J. I. Anal. Chim. Acta 1990, 234, 365-380.
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Armstrong, D.W.1
Li, W.2
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Secor, H.V.4
Izac, R.R.5
Seeman, J.I.6
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33
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85039562853
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note
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8 was used because the determination of the ee of the product from the corresponding Nf-protected compound proved difficult.
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