Modeling techniques for analysing conformational transitions in hemocyanins by small-angle scattering of X-rays and neutrons

Micron

Volumn 35, Issue 1-2, 2004, Pages 11-13

  Hartmann, Hermann ^a   Müller, Tobias ^a   Decker, Heinz ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 1242277891     PISSN: 09684328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micron.2003.10.004     Document Type: Conference Paper

References (10)

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2. Decker H., Hartmann H., Sterner R., Schwarz E., Pilz I. Small-angle X-ray scattering reveals differences between the quaternary structures of oxygenated and deoxygenated tarantula hemocyanin. FEBS Lett. 393:1996;226-230.
3. Hartmann H., Bongers A., Decker H. Small-angle neutron scattering reveals an oxygen-dependent conformational change of the immunogen keyhole limpet hemocyanin type 1 (KLH1). Eur. Biophys. J. 30:2001;471-475.
4. Hartmann H., Lohkamp B., Hellmann N., Decker H. The allosteric effector L-lactate induces a conformational change of 2×6-meric lobster hemocyanin in the oxy state as revealed by small angle X-ray scattering. J. Biol. Chem. 276:2001;19954-19958.
5. Hartmann H., Decker H. All hierarchical levels are involved in conformational transitions of the 4×6-meric tarantula hemocyanin upon oxygenation. Biochim. Biophys. Acta. 1601:2002;132-137.
6. Hartmann H., Decker H. Small-angle scattering techniques for analysing conformational transitions in hemocyanins. Holt J.M., Johnson M.L., Ackers G.K. Methods in Enzymology. 2003;Academic Press, London. in press.
7. Hartmann, H., Bongers, A., Decker, H., 2004. Small-angle X-ray scattering based 3D reconstruction of the immunogen KLH1 reveals different oxygen dependent conformations. J. Biol. Chem., in press.
8. Hazes B., Magnus K.A., Bonaventura C., Bonaventura J., Dauter Z., Kalk K.H., Hol W.G. Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation. Protein Sci. 2:1993;597-619.
9. Svergun D.I. Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing. Biophys. J. 76:1999;2879-2886.
10. Svergun D.I., Koch M.H. Advances in structure analysis using small-angle scattering in solution. Curr. Opin. Struct. Biol. 12:2002;654-660.