The Noc proteins involved in ribosome synthesis and export contain divergent HEAT repeats

RNA

Volumn 10, Issue 3, 2004, Pages 351-354

  Dlakić, Mensur ^a,b   Tollervey, David ^b  

^a MONTANA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Molecular models; Ribonucleoproteins; Ribosome formation; rRNA; Yeast

Indexed keywords

PROTEIN NOC; PROTEIN NOC1P; PROTEIN NOC2P; PROTEIN NOC3P; PROTEIN NOC4P; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ARABIDOPSIS; ARTICLE; CELL NUCLEUS INCLUSION BODY; INTRACELLULAR TRANSPORT; INTRANUCLEAR TRANSPORT; MOLECULAR MECHANICS; MOLECULAR RECOGNITION; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RIBOSOME; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; STRUCTURE ANALYSIS; TRANSPORT KINETICS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CARRIER PROTEINS; HEAT-SHOCK PROTEINS; INTERMEDIATE FILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; PROTEIN STRUCTURE, TERTIARY; RIBOSOMES; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES POMBE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN;

ARABIDOPSIS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE;

EID: 1242274332     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1261/rna.5184704     Document Type: Article

References (30)

1. Altschul, S.F., Madden, T.L., Schaffer, A.A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D.J. 1997. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 25: 3389-3402.
2. Andrade, M.A. and Bork, P. 1995. HEAT repeats in the Huntington's disease protein. Nat. Genet. 11: 115-116.
3. Andrade, M.A., Petosa, C., O'Donoghue, S.I., Muller, C.W., and Bork, P. 2001. Comparison of ARM and HEAT protein repeats. J. Mol. Biol. 309: 1-18.
4. Bateman, A., Birney, E., Durbin, R., Eddy, S.R., Howe, K.L., and Sonnhammer, E.L. 2000. The Pfam protein families database. Nucleic Acids Res. 28: 263-266.
5. Chook, Y.M. and Blobel, G. 1999. Structure of the nuclear transport complex karyopherin-β2-Ran-GppNHp. Nature 399: 230-237.
6. Cingolani, G., Petosa, C., Weis, K., and Muller, C.W. 1999. Structure of importin-β bound to the IBB domain of importin-α. Nature 399: 221-229.
7. Dragon, F., Gallagher, J.E., Compagnone-Post, P.A., Mitchell, B.M., Porwancher, K.A., Wehner, K.A., Wormsley, S., Settlage, R.E., Shabanowitz, J., Osheim, Y., et al. 2002. A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417: 967-970.
8. Fatica, A. and Tollervey, D. 2002. Making ribosomes. Curr. Opin. Cell Biol. 14: 313-318.
9. Fatica, A., Cronshaw, A.D., Dlakic, M., and Tollervey, D. 2002. Ssflp prevents premature processing of an early pre-60S ribosomal particle. Mol. Cell 9: 341-351.
10. Ginalski, K., Elofsson, A., Fischer, D., and Rychlewski, L. 2003. 3D-Jury: A simple approach to improve protein structure predictions. Bioinformatics 19: 1015-1018.
11. Gorlich, D., Dabrowski, M., Bischoff, F.R., Kutay, U., Bork, P., Hartmann, E., Prehn, S., and Izaurralde, E. 1997. A novel class of RanGTP binding proteins. J. Cell Biol. 138: 65-80.
12. Grandi, P., Rybin, V., Bassler, J., Petfalski, E., Strauss, D., Marzioch, M., Schafer, T., Kuster, B., Tschochner, H., Tollervey, D., et al. 2002. 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol. Cell 10: 105-115.
13. Groves, M.R., Hanlon, N., Turowski, P., Hemmings, B.A., and Barford, D. 1999. The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 96: 99-110.
14. Harnpicharnchai, P., Jakovljevic, J., Horsey, E., Miles, T., Roman, J., Rout, M., Meagher, D., Imai, B., Guo, Y., Brame, C.J., et al. 2001. Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol. Cell 8: 505-515.
15. Johnson, A.W., Lund, E., and Dahlberg, J. 2002. Nuclear export of ribosomal subunits. Trends Biochem. Sci. 27: 580-585.
16. Jorgensen, P., Tyers, M., and Warner, J.R. 2004. Forging the factory: Ribosome synthesis and growth control in budding yeast. In: Cell growth: control of cell size (eds. M.N. Hall et al.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (in press).
17. Kelley, L.A., MacCallum, R.M., and Sternberg, M.J. 2000. Enhanced genome annotation using structural profiles in the program 3D-PSSM. J. Mol. Biol. 299: 499-520.
18. Kobe, B., Gleichmann, T., Horne, J., Jennings, I.G., Scotney, P.D., and Teh, T. 1999. Turn up the HEAT. Structure 7: R91-R97.
19. Malik, H.S., Eickbush, T.H., and Goldfarb, D.S. 1997. Evolutionary specialization of the nuclear targeting apparatus. Proc. Natl. Acad. Sci. 94: 13738-13742.
20. Milkereit, P., Gadal, O., Podtelejnikov, A., Trumtel, S., Gas, N., Petfalski, E., Tollervey, D., Mann, M., Hurt, E., and Tschochner, H. 2001. Maturation and intranuclear transport of pre-ribosomes requires Noc proteins. Cell 105: 499-509.
21. Milkereit, P., Strauss, D., Bassler, J., Gadal, O., Kuhn, H., Schutz, S., Gas, N., Lechner, J., Hurt, E., and Tschochner, H. 2003. A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits. J. Biol. Chem. 278: 4072-4081.
22. Nicholls, A., Sharp, K.A., and Honig, B. 1991. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 11: 281-296.
23. Nissan, T.A., Bassler, J., Petfalski, E., Tollervey, D., and Hurt, E. 2002. 60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm. EMBO J. 21. 5539-5547.
24. Oeffinger, M., Dlakic, M., and Tollervey, D. 2004. A pre-ribosome associated HEAT-repeat protein is required for export of both ribosomal subunits. Genes & Dev. 18: 196-209.
25. Pei, J., Sadreyev, R., and Grishin, N.V. 2003. PCMA: Fast and accurate multiple sequence alignment based on profile consistency. Bioinformatics 19: 427-428.
26. Sali, A. and Blundell, T.L. 1993. Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 234: 779-815.
27. Sanchez, R. and Sali, A. 1998. Large-scale protein structure modeling of the Saccharomyces cerevisiae genome. Proc. Natl. Acad. Sci. 95: 13597-13602.
28. Tschochner, H. and Hurt, E. 2003. Pre-ribosomes on the road from the nucleolus to the cytoplasm. Trends Cell Biol. 13: 255-263.
29. Vetter, I.R., Arndt, A., Kutay, U., Gorlich, D., and Wittinghofer, A. 1999. Structural view of the Ran-Importin β interaction at 2.3 Å resolution. Cell 97: 635-646.
30. Zhang, Y., Yu, Z., Fu, X., and Liang, C. 2002. Noc3p, a bHLH protein, plays an integral role in the initiation of DNA replication in budding yeast. Cell 109: 849-860.