Development of a targeted transgenesis strategy in highly differentiated cells: A powerful tool for functional genomic analysis

Journal of Biotechnology

Volumn 116, Issue 2, 2005, Pages 145-151

  Puttini, Stefania ^a   Ouvrard Pascaud, Antoine ^a   Palais, Gael ^a   Beggah, Ahmed T ^a   Gascard, Philippe ^b   Cohen Tannoudji, Michel ^c   Babinet, Charles ^c   Blot Chabaud, Marcel ^a   Jaisser, Frederic ^a  

^a INSERM   (France)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c INSTITUT PASTEUR   (France)

Author keywords

Conditional; Differentiated cells; Targeted transgenesis

Indexed keywords

ENZYMES; GENES; GENETIC ENGINEERING; MUTAGENESIS; PHYSIOLOGICAL MODELS;

GENE EXPRESSION ANALYSIS; RECOMBINANT CELLS; TRANSFECTION; TRANSGENESIS;

CELLS;

NUCLEASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CONTROLLED STUDY; DNA MODIFICATION; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENE INDUCTION; GENE LOCUS; GENETIC RECOMBINATION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SOUTHERN BLOTTING; TRANSGENICS; WESTERN BLOTTING;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CHROMOSOME MAPPING; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE TARGETING; GENE TRANSFER TECHNIQUES; RATS; RECOMBINANT PROTEINS;

EID: 12344337368     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2004.10.014     Document Type: Article

References (11)

1. M. Blot-Chabaud, M. Laplace, F. Cluzeaud, C. Capurro, R. Cassingena, A. Vandewalle, N. Farman, and J.P. Bonvalet Characteristics of a rat cortical collecting duct cell line that maintains high transepithelial resistance Kidney Int. 50 1996 367 376
2. H. Bujard Controlling genes with tetracyclines J. Gene Med. 1 1999 372 374
3. A. Choulika, A. Perrin, B. Dujon, and J.F. Nicolas Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae Mol. Cell. Biol. 15 1995 1968 1973
4. M. Cohen-Tannoudji, S. Robine, A. Choulika, D. Pinto, F. El Marjou, C. Babinet, D. Louvard, and F. Jaisser I-SceI-induced gene replacement at a natural locus in embryonic stem cells Mol. Cell. Biol. 18 1998 1444 1448
5. G. Donoho, M. Jasin, and P. Berg Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells Mol. Cell. Biol. 18 1998 4070 4078
6. M. Jasin Genetic manipulation of genomes with rare-cutting endonucleases Trends Genet. 12 1996 224 228
7. R.D. Johnson, and M. Jasin Double-strand-break-induced homologous recombination in mammalian cells Biochem. Soc. Trans. 29 2001 196 201
8. S. Lamartina, G. Roscilli, C.D. Rinaudo, E. Sporeno, L. Silvi, W. Hillen, H. Bujard, R. Cortese, G. Ciliberto, and C. Toniatti Stringent control of gene expression in vivo by using novel doxycycline-dependent trans-activators Hum. Gene Ther. 13 2002 199 210
9. P. Pognonec, and J.C. Chambard A reliable way of obtaining stable inducible clones Nucl. Acids Res. 26 1998 3443 3444
10. S. Puttini, A.T. Beggah, A. Ouvrard-Pascaud, C. Legris, M. Blot-Chabaud, N. Farman, and F. Jaisser Tetracycline-inducible gene expression in cultured rat renal CD cells and in intact CD from transgenic mice Am. J. Physiol. Renal Physiol. 281 2001 1164 1172
11. K. Ye, D.A. Compton, M.M. Lai, L.D. Walensky, and S.H. Snyder Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor J. Neurosci. 19 1999 10747 10756