Zinc-mediated intramolecular acyl and imino transfer reactions of aryl iodides

Tetrahedron Letters

Volumn 46, Issue 6, 2005, Pages 983-986

  Boulton, Lee T ^a   Fox, Martin E ^a   Hodgson, Paul B ^b   Lennon, Ian C ^a  

^a DOW CHEMICAL COMPANY   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Aromatic substitution; Crosscoupling reactions; Heterocyclic chemistry; Negishi coupling; Organozinc reagent

Indexed keywords

4 AMINO 5 IODOQUINAZOLINE; 4 AMINOQUINAZOLINE; FUNCTIONAL GROUP; IODIDE; PYRIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG; ZINC;

ARTICLE; METHODOLOGY; SUBSTITUTION REACTION; SYNTHESIS;

EID: 12344333452     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.12.034     Document Type: Article

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22. 6) δ ppm 7.84 (1H, dt, J = 6.8, 1.0), 7.47 (1H, ddd, J = 9.1, 6.4, 1.0), 7.30 (1H, d, J = 9.1) 7.02 (1H, s), 6.44 (1H, td, J = 6.7, 1.0), 3.91 (3H, s), 3.68 (3H, s) and 1.41 (9H, s)