Medicinal treatment to equine gastrointestinal dysfunctions

Journal of Equine Science

Volumn 14, Issue 2, 2003, Pages 37-49

  Sasaki, Naoki ^a   Yamada, Haruo ^a   Hara, Shigeo ^b  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

^b IWATE UNIVERSITY   (Japan)

Author keywords

2 adrenergic agonist; Equine; Gastrointestinal dysfunction; Motility; Serotonin receptor agonist

Indexed keywords

CANIS FAMILIARIS; EQUIDAE; EQUUS CABALLUS;

EID: 12344321874     PISSN: 13403516     EISSN: None     Source Type: Journal    
DOI: 10.1294/jes.14.37     Document Type: Review

References (76)

1. Adams, S.B., Lamar, C.H., and Masty, J. 1984. Motility of the distal portion of the jejunum and pelvic flexure in ponies: effects of six drugs. Am. J. Vet. Res. 45: 795-799.
2. Brown, J.C., Cook, M.A., and Dryburgh, J.R. 1973. Motilin, a gastric motor activity stimulating polypeptide: the complete amino acid sequence. Can. J. Biochem. 51: 533-537.
3. Camilleri, M., Northcutt, A., and Kong, S. 2000. Efficacy and safety of alosetron I women with irritable bowel syndrome: a randomized, placebocontrolled rial. Lancet 355: 1035-1040.
4. Carlo, D.L., Alejandro, F.F., Tim, B., and Paul, E.H. 1995. Intestinal Motility and jejunal feeding in children with chronic intestinal pseudoobstruction. Gastroenterol. 108: 1379-1385.
5. Clarke, L.L., Roberts, M.C., and Argenzio, R.A. 1990. Feeding and digestive problems in horses. In: The Veterinary Clinics of North America, Equine Practice , Clinical Nutrition. Turner, A. S. ed, W. B. Saunders, Philadelphia, pp.433-450.
6. Clark, E.S. and Moore, J.N. 1989. Effects of dopamine administration on cecal mechanical activity and cecal blood flow in conscious healthy horses. Am. J. Vet. Res. 50: 1084-1088.
7. Code, C.F. and Marlett, J.A. 1975. The interdigestive myo-electric complex of the stomach and small bowel of dogs. J. Physiol. 246: 289-309.
8. Eades, S.C. and Moore, J.N. 1993. Blockade of endotoxin-induced cecal hypoperfusion and ileus with an alpha 2 antagonist in horses. Am. J. Vet. Res. 54: 586-590.
9. Edward, D. M. 1998. Management of adynamic ileus. In: Equine Internal Medicine. Sephaen, M.R. and Warwick, M.B. eds. W. B. Saunders, Philadelphia, pp.602-694.
10. Feighner, S.D. 1999. Receptor for motilin identified in the human gastrointestinal system. Science 284: 2184-2188.
11. Fleckenstein, P., Bueno, L., Fioramonti, J., and Ruckebusch, Y. 1982. Minute rhythm of electrical spike bursts of the small intestine in different species. Am. Physiol. Society 242: 654-659.
12. Fujii, K., Okajima M., and Kawahori, K. 1988. Effect of cisapride on the cholinergic control mechanisms of gastrointestinal motility in dogs. Jpn. J. Smooth Muscle Res. 24: 1-12.
13. Furukawa, Y. 1987. Pyloric motor activity and function with special refference to pyloroplasty after vagotomy. Jpn. J. Smooth Muscle Res. 23: 75-102.
14. Gerring, E.L. 1989. Effects of pharmacological agents on gastrointestinal motility. In: The Veterinary Clinics of North America, Equine Practice, Advances In Equine Abdominal Surgery. Snyder, J.R. and Markel, M.D. eds. W.B. Saunders, Philadelphia, pp.283-294
15. Gerring, E.L. 1991. All wind and water: some progress in the study of equine gut motility. Equine Vet. J. 23: 81-85.
16. Gerring, E.L. and Hunt, J.M. 1986. Pathophysiology of equine postoperative ileus: Effect of adrenergic blockade, parasympathetic stimulation and metoclopramide in an experimental madel. Equine Vet. J. 18: 249-355.
17. Gerring, E.L. and King, N. 1989. Cisapride in prophylaxis of equine post operative ileus. Equine Vet. J. 7: 52-55.
18. Hanson, R.R., Schumacher, J., Humburg, J., and Dunkererley, S.C. 1996. Medical treatment of horses with ileal impactions : 10 cases (1990-1994). J. Am. Vet. Med. Assoc. 208: 898-900.
19. Hunrt, J.M. and Gerring, E.L. 1985. The effect of prostaglandin El on motility of the eqnine gut. J. Vet. Pharmacol Therap. 8: 165-173.
20. Koyama, K. 1995. Gastric emptying of semi-solid meal in normal man with special reference to relationship between plasma acetoaminophen concentrations and gastric emptying time. J. Smooth. Muscle Res. 31: 61-65.
21. Itakura, M. 1995. Effects of low anterior resection on colonic motor activity and defecation, an experimental study. J. Smooth Muscle Res. 31: 79-91.
22. Itoh, Z. 1996. Motilin and its clinical application. Nippon Shokakibyo Gakkai Zasshi 93: 517-529.
23. Itoh, Z. 1997. Motilin and clinical application. Peptides 18: 593-608.
24. Itoh, Z., Honda, R., and Takeuchi, S. 1977. An extraluminal force transducer for recording contractile activity of the gastrointestinal smooth muscle in the conscious dog; its construction and implantation. Gastoenterol. Jpn. 12: 275-283.
25. Jacoby, H.I. and Bennett, D.R. 1963. In vivo extraluminal contractile force transducer for gastrointestinal muscle. J. Appl. Physiol. 18: 658-665.
26. King, J.N. and Gerring, E.L. 1998. Actions of the novel gastrointestinal prokinetic agent cisapride on equine bowel motility. J. Vet. Pharmacol. Ther. 11: 314-321.
27. King, J.N. and Gerring, E.L. 1991. The action of low dose endotoxin on equine bowel motility. Equine Vet. J. 23: 11-17.
28. Lamar, C.H., Masty, J., Adams, S.B., and Tacker, W.A. 1984. Impedance monitoring of equine intestinal motility. Am. J. Vet. Res. 45: 810-812.
29. Lowe, J.E., Sellers, A.F., and Brondum, J. 1980. Equine pelvic flexure impaction a model used to evaluate motor events and compare drug response. Conell Vet. 70: 401-412.
30. Macharg, M.A., Adams, S.B., Lamar, C.H., and Becht, J.L. 1986. Electromyographic, myomechanical, and intraluminal pressure changes associated with acute extraluminal obstruction of the jejunum in conscious ponies. Am. J. Vet. Res. 47: 7-11.
31. Malone, E.D., Brown, D.R., Trent, A.M., and Turner, T.A. 1996. Influence of adrenergic and cholinergic mediators on the equine jejunum in vitro. Am. J. Vet. Res. 57: 884-890.
32. Matsumoto, T., Sarna, S.K., Condon, R.E., Cowles, V.E., and Frantzides, C.A. 1986. Differential sensitivities of morphine and motilin to initiate migrating motor complex in isolated intestinal segments. Gastroenterol. 90: 61-67.
33. Merritt, A.M., Campbell-Thompson, M.L., and Lowrey, S. 1989. Effect of xylazine treatment on equine proximal gastrointestinal tract myoelectrical activity. Am. J. Vet. Res. 50: 945-949.
34. Milne, E.M., Doxey, D.L., Woodman, M.P., Guddeford, D., and Pearson, R.A. 1996. An evaluation of the use of cisapride in horses with chronic grass sickness (Equine dysautonomia). Br. Vet. J. 152: 537-549.
35. Nakata, Y. 1999. Pharmacological effects of the gastroprokinetic agent mosapride citrate. Folia Pharmacal. Jpn. 113: 299-307.
36. Nieuwenhuijs, V.B., Verheem, A., Beumer, H.D., Visser, M., Verhoef, J., Gooszen, H.G., and Akkermans, L.M.A. 1998. The role of interdigestive small bowel motility in the regulation of gut microflora, bacterial overgrowth, and bacterial translocation in rats. Annals Surg. 228: 188-193.
37. Nishikawa, K. 1999. Experimental study on gastrointestinal motility in inflammatory bowel disease. J. Smooth Muscle Res. 3: 81-94.
38. Ohira, Y. 1988. An experimental study on the remnant gastric motilities and gastrointestinal hormons after various types of gastrectomies. Jpn. J. Smooth Muscle Res. 24: 79-100.
39. Prather, C., Camillerrim, M., and Zinsmeister, A.R. 2000. Tegaserod accerelates transit in patients with constipation-predominant irritable bowel syndrome. Gastroenterol. 118: 463-468.
40. Ringger, N.C., Lester, G.D., Neuwirth, L., Merritt, A.M., Vetro, T., and Harrison, J. 1996. Effect of bethanechol or erythromycin on gastric emptying in horses. Am. J. Vet. Res. 57: 1771-1775.
41. Riordan, S.M., Mclver, C.J., Wakefield, D., Bolin, T.B., Duncombe, V.M., and Thomas, M. 1996. Small intestinal bacterial overgrowth in the symptomatic elderly. Am. J. Gastroenterol. 92: 47-51.
42. Robert, J.W. and Jean, A.H. 1995. Cisapride. J. Am. Vet. Med. Assoc. 207: 1285-1288.
43. Roger, T., Bardon, T., and Ruckebusch, Y. 1985. Colonic motor responses in the pony: relevance of colonic stimulation by opiate antagonists. Am. J. Vet. Res. 46: 32-35.
44. Roger, T.R. and Ruckebusch, Y. 1987. Phamacological modulation of postprandial colonic motor activity in the pony. J. Vet. Phamacol. Therap. 10: 273-282.
45. 2- adrenoceptor-mediated responses in the pony. J. Vet. Pharmacol. Therap. 10: 310-318.
46. Roger, T. and Ruckebusch, Y. 1987. Pharmacological modulation of postpradial colonic motor activity in the pony. J. Vet. Pharmacol. Therap. 10: 273-282.
47. Ross, M.W., Donawick, W.J., Sellers, A.F., and Lowe, J.E. 1986. Normal motility of the cecum and right ventral colon in ponies. Am. J. Vet. Res. 47: 1756-1762.
48. Ross, M.W., Rutkowsi, J.A., and Gullen, K.K. 1989. Myoelectric activity of the cecum and right ventral colon in female ponies. Am. J. Vet. Res. 50: 374-379.
49. Ross, M.W., Cullen, K.K., and Rutkowski, J.A. 1990. Myoelectric activity of the ileum, cecum, and right ventral colon in ponies during interdigestive, nonfeeding, and digestive periods. Am. J. Vet. Res. 51: 561-566.
50. Ruckebusch, Y. 1989. Gastrointestinal motor functions in ruminants. In: The gastrointestinal system Vol. 1 motility and circulation. Schultz, S.G. and Wood, J.D. eds. Handbook Physiology, France, pp. 1225-1282.
51. Ruckebusch, Y. and Bueno, L. 1976. The effect of feeding on the motility of the stomach and small intestine in the pig. Br. J. Nutr. 35: 397-405.
52. Rutkowski, J.A., Eades, S.C., and Moore, J.N. 1991. Effects of xylazine and butorphanol on cecal arterial blood flow, cecal mechanical activity, and systemic hemodynamics in horses. Am. J. Vet. Res. 52: 1153-1158.
53. Ruckebusch, Y., Grivel, M.L., and Hatey, F. 1971. Etude electromyographique du profil moteur de intestine grele chez le cheval (Equus caballus). Soc. Sci. Vet. 70: 337-346.
54. Rutkowski, J.A., Ross, M.W., and Cullen, K. 1989. Effects of xylazine and/or butorphanol or neostigmine on myoelectric activity of the cecum and right ventral colon in female ponies. Am. J. Vet. Res. 50: 1096-1101.
55. Sarna, S.K. 1991. Physiology and pathophysiology of colonic motor activity (Part One of Two). Dig. Dis. Sci. 36, 827-862.
56. Sasaki, N. and Yoshihara, T. 1999. The effect of motilin on the regulation mechanism of instinal motility in conscious horses. J. Vet. Med. Sci. 61: 167-170.
57. Sasaki, N., Yoshihara, T., and Hara, S. 2000. Difference in the motile reactivity of jejunum, cecum, and right ventral colon to xylazine and medetomidine in conscious horses. J. Equine Sci. 11: 63-68.
58. Sasaki, N. and Yoshihara, T. 2000. The effect of orally administered cisapride on intestinal motility in conscious horses. J. Vet. Med. Sci. 62: 211-213.
59. Schoeman, M.N., Tippett, M.D., Akkermans, L.M., Dent, J., and Holloway, R.H. 1995. Mechanisms of gastroesophageal reflux in ambulant healthy human subjects. Gastroenterol. 108: 83-91.
60. Sifrim, D., Janssens, J., and Vantrappen, G. 1996. Transient lawer esophageal sphincter relaxations and esophageal body muscular contractile response in normal humans. Gastroenterol. 110: 659-668.
61. Sojka, J.E., Adams, S.B., Lamar, C.H., and Eller, L.L. 1988. Effect of butorphao, pentazocine, meperidine, or metoclopramide on intestinal motility in female ponies. Am. J. Vet. Res. 49: 527-529.
62. Steel, C.M., Bolton, J.R., Preechagon, Y., and Charles, B.G. 1999. Unreliablerectal absorption of cisapride in horses. Equine Vet. J. 31: 82-84.
63. Steinebach, M.A. and Cole, D. 1995. Use of cisapride in the resolution of pelvic flexure impation in a horse. Can. Vet. J. 36: 624-625.
64. Stephen, B. Adams., Carlton, H.L., and Jerome, M. 1984. Motility of distal portion of thejejunum and pelvic flexure in ponies: effects of six drugs. Am. J. Vet. Res. 45: 795-799.
65. Szurszewski, J.H. 1969. A migrating electric complex of the canine small intestine. Am. J. Physiol. 217: 1757-1763.
66. Tanaka, J. 1994. A clinical study of motor activity and neural control of human sphincter of oddi in post-operative state of cholecystocholedocholithiasis. J. Smooth Muscle Res. 30: 177-188.
67. Taniyama, K., Nakayama, S., Takeda, K., Matsutama, S., Shirakawa, J., Sana, I., and Tanaka, C. 1991. Cisapride stimulates motility of the intestine via the 5-hydroxytryptamine receptors. J. Phamacol. Exp. Ther. 258: 1098-1104.
68. Tomimuro, T., Koh, K., and Kayama, H. 1999. An experimental study about the mechanism and the prevention of postoperative gastric stasis following pylorus preserving pancreatoduodenectomy. J. Smooth Muscle Res. 3: 69-79.
69. Vantrappen, G., Janssens, J., Hellemans, J., and Gohoos, Y. 1977. The interdigestive motor complex of normal subjects and patients with bacterial overgrowth of the small intestine. J. Clin. Invest. 59: 1158-1166.
70. Velden, M.A. and Klein, W.R. 1993. The effects of cisapride on the restoration of gut motility after surgery of the small intestine in horses; a clinical trial. Vet. Q. 15: 175-179.
71. Walton, R.P., Leary, J.S., and Jones, H.P. 1950. Comparative increase in ventricular contractive force produced by several cardiac glycosides. J. Prarmacol. Exptl. Therap. 98: 346-357.
72. White II, N.A. and Byars, T.D. 1990. Anagesia. In: The Equine Acute Abdomen. Nathaniel, A. and White, I. I.eds. Lea & Febiger, Philadelphia, pp. 154-159.
73. Yamada, T., Mizumoto, A., Satoh, M., Haga, N., and Itoh, Z. 1997. Muscarinic control of phase III contractions and motilin release in dogs. Peptides 18: 673-680.
74. Yamamoto, H., Kuwahara, A., Yamamoto, I., Fujimura, M., Maeda, T., and Fujimiya, M. 1999. Motor activity of vascularly perfused rat duodenum. 1. Characteristics of spontaneous movement. Neurogastroenterol. Mot. 11: 227-234.
75. Yoshida, N., Ito, I., and Karasawa, T. 1991. AS-4370, a new gastrokinetic agent, enhances upper gastrointestinal motor activity in conscious dogs. J. Phamacol. Exp. Ther. 257: 781-787.
76. 4receptor agonist in the gut. Neurogastroenterology 6: 197-204.