Micellar electrokinetic chromatography for determination of drug partition in phospholipids

Farmaco

Volumn 60, Issue 1, 2005, Pages 77-83

  Quaglia, M G ^a   Fanali, S ^b   Barbato, F ^c   Donati, E ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Cholic acid sodium salt; Lipophilicity; Micellar electrokinetic chromatography; Mixed micelles; Nalidixic acid; Phosphotidylcholine derivatives; Pipemidic acid

Indexed keywords

BUFFER; CHOLIC ACID; DILAUROYLPHOSPHATIDYLCHOLINE; NALIDIXIC ACID; OXOLINIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; PIPEMIDIC ACID; QUINOLONE DERIVATIVE;

ARTICLE; CAPILLARY ELECTROPHORESIS; DRUG DETERMINATION; LIPOPHILICITY; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; PH;

ANTI-INFECTIVE AGENTS; CHROMATOGRAPHY, MICELLAR ELECTROKINETIC CAPILLARY; NALIDIXIC ACID; OXOLINIC ACID; PHOSPHOLIPIDS; PIPEMIDIC ACID;

EID: 12344318441     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2004.10.003     Document Type: Article

References (19)

1. C. Pidgeon, S. Ong, H. Liu, X. Qiu, M. Pidgeon, and A.H. Dantzig IAM Chromatography: an in vitro screen for predicting drug membrane permeability J. Med. Chem. 38 1995 590 594
2. A. Taillardat-Bertschinger, P.A. Carrupt, F. Barbato, and B. Testa Immobilized artificial membrane HPLC in drug research J. Med. Chem. 46 2003 655 665
3. C. Hansh, A. Leo, and D.H. Hoekman Exploring QSAR, vol. 1 1995 American Chemical Society Washington, DC
4. C. Pidgeon, and U.V. Venkataram Immobilized artificial membrane chromatography: supports composed of membrane lipids Anal. Biochem. 176 1989 36 47
5. S. Ong, H. Lui, X. Qiu, G. Bath, and C. Pidgeon Membrane partition coefficients chromatographically measured using immobilized artificial membrane surfaces Anal. Chem. 67 4 1995 755 762
6. C. Yang, S.J. Cai, H. Liu, and C. Pidgeon Immobilized artificial membranes--screens for drug membrane interactions Adv. Drug Del. Rev. 23 1997 229 256
7. F. Beigi, Q. Yang, and P. Lundahl Immobilized--Liposome Chromatographic analysis of drug partitioning into lipid bilayers J. Chromatogr. A. 704 1995 315 321
8. P. Lundahl, and F. Beigi Immobilized liposome chromatography of drug for model analysis of drug-membrane interactions Adv. Drug Del. Rev. 23 1997 221 227
9. K.L. Morse, and C. Pidgeon Pharmacokinetic Optimization in Drug Research 2001 Wiley-VCH Zurich
10. L.R. Snyder, and J.J. Kirkland Introduction to Modern Liquid Chromatography 1979 John Wiley & Sons New York
11. M.G. Quaglia, F. Barbato, S. Fanali, E. Santucci, E. Donati, and M. Carafa Direct determination by capillary electrophoresis of cardiovascular drugs, previously included in liposomes J. Pharm. Biom. Anal. 2004 (in press)
12. J.G. Hardman L.E. Limbird Goodman & Gilman's The Pharmacological Basis of Therapeutics, tenth ed 2001 McGraw-Hill New York
13. S.T. Burns, and M.G. Khaledi Rapid determination of liposome-water partition coefficients (KIw) using liposome electrokinetic chromatography (LEKC) J. Pharm. Sci. 91 2002 1601 1612
14. Lipophilicity in drug action and toxicology Eds. V. Pliska B. Testa and H. van de Waterbeemd. VCH Publishers, Wanheim, 1996. pp. 49-71.
15. F. Barbato, G. Di Martino, L. Grumetto, M.I. La Rotonda. "Chromatographic Indices on immobilized artificial membrane for quinolone antibacterial agents".
16. rd Lipophilicity Symposium - Physicochemical and Biological Profiling in Drug Research, Zürich (CH) February 29 - March 4, 2004.
17. P.N.Craig - Drug Compendium in "Comprehensive Medicinal Chemistry". Eds. C. Hansch, P.G. Sammes, J.B. Taylor. Pergamon. New York. 1990. pag. 237 vol. 6.
18. B. Testa, P.A. Carrupt, P. Gaillard, and R.S. Tsai V. Pliska B. Testa H. Van de Waterbeemd Lipophilicity in Drug Action and Toxicology 1996 VCH Publishers Weinheim 49 71
19. G. Caron, S. Rey, G. Ermondi, P. Crivori, P. Gaillard, and P.A. Carrupt Molecular hydrogen- bonding potentials (MHBPs) in structure-permeation relations B. Testa H. van de Waterbeemd G. Folkers R. Guy Pharmacokinetic Optimization in Drug Research 2001 Wiley-VCH Publishers New York 525 536