Enhanced ligand affinity for receptors in which components of the binding site are independently mobile

Chemistry and Biology

Volumn 12, Issue 1, 2005, Pages 89-97

  Trevitt, Clare R ^a   Craven, C Jeremy ^a   Milanesi, Lilia ^a   Syson, Karl ^a   Mattinen, Maija Liisa ^a,b   Perkins, Julie ^a   Annila, Arto ^c   Hunter, Christopher A ^a   Waltho, Jonathan P ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM SENSING RECEPTOR; CALMODULIN; DRUG DERIVATIVE; LIGAND; NAPHTHALENE DERIVATIVE; PEPTIDE; SULFONAMIDE; TRYPTAMINE; TRYPTAMINE DERIVATIVE; TRYPTOPHAN;

ANIMAL; ARTICLE; BINDING COMPETITION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MOLECULAR MIMICRY; MOVEMENT (PHYSIOLOGY); PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; SYNTHESIS;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CALMODULIN; LIGANDS; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; MOVEMENT; NAPHTHALENES; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CALCIUM-SENSING; SULFONAMIDES; TRYPTAMINES; TRYPTOPHAN;

EID: 12344315072     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2004.11.007     Document Type: Article

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