Matrix metalloproteinase-13 (MMP-13, collagenase-3) is highly expressed in human tooth pulp

Connective Tissue Research

Volumn 45, Issue 4-5, 2004, Pages 231-237

  Sulkala, Merja ^a   Pääkkönen, Virve ^a   Larmas, Markku ^a,b   Salo, Tuula ^a,b   Tjäderhane, Leo ^c  

^a UNIVERSITY OF OULU   (Finland)

^b OULU UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Caries; Collagenase; MMP; Pulp

Indexed keywords

COLLAGENASE; COLLAGENASE 16; COLLAGENASE 3; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MOLAR TOOTH; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; TOOTH PULP; WESTERN BLOTTING;

ADULT; BLOTTING, WESTERN; COLLAGENASES; DENTAL CARIES; DENTAL PULP; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASE 13; MOLAR, THIRD; ODONTOBLASTS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASES;

EID: 12344301876     PISSN: 03008207     EISSN: None     Source Type: Journal    
DOI: 10.1080/03008200490885788     Document Type: Article

References (36)

1. Sternlicht, M.D., and Werb, Z. (2001). How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 17:463-516.
2. Gomez, D.E., Alonso, D.F., Yoshiji, H., and Thorgeirsson, U.P. (1997). Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions. Eur. J. Cell Biol. 74:111-122.
3. Llano, E., Pendas, A.M., Knäuper, V., Sorsa, T., Salo, T., Salido, E., Murphy, G., Simmer, J.P., Bartlett, J.D., and Lopez-Otin, C. (1997). Identification and structural and functional characterization of human enamelysin (MMP-20). Biochemistry 36:15101-15108.
4. Tjäderhane, L., Salo, T., Larjava, H., Larmas, M., and Overall, C.M. (1998). A novel organ culture method to study the function of human odontoblasts in vitro: Gelatinase expression by odontoblasts is differentially regulated by TGF-β1. J. Dent. Res. 77:1486-1496.
5. Palosaari, H., Wahlgren, J., Larmas, M., Rönkä, H., Sorsa, T., Salo, T., and Tjäderhane, L. (2000). The expression of MMP-8 in human odontoblasts and dental pulp cells is down-regulated by TGF-. J. Dent. Res. 79:77-84.
6. Palosaari, H., Ding, Y., Larmas, M., Sorsa, T., Bartlett, J.D., Salo, T., and Tjäderhane, L. (2002). Regulation and interactions of MT1-MMP and MMP-20 in human odontoblasts and pulp tissue in vitro. J. Dent. Res. 81:354-359.
7. Sulkala, M., Larmas, M., Sorsa, T., Salo, T., and Tjäderhane. L. (2002). The localization of matrix metalloproteinase-20 (MMP-20, Enamelysin) in mature human teeth. J. Dent. Res. 81:603-607.
8. Palosaari, H., Pennington, C.J., Larmas, M., Edwards, D.R., Tjäderhane, L., and Salo, T. (2003). Expression profile of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in mature human odontoblasts and pulp tissue. Eur. J. Oral Sci. 111:117-127.
9. Tjäderhane, L., Larjava, H., Sorsa, T., Uitto, V.-J., Larmas, M., and Salo, T. (1998). The activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesion. J. Dent. Res. 77:1622-1629.
10. Tjäderhane, L., Sulkala, M., Sorsa, T., Teronen, O., Larmas, M., and Salo, T. (1999). The effect of MMP inhibitor Metastat on fissure caries progression in rats. Ann. NY Acad. Sci. 878:686-688.
11. Martin-De Las Heras, S., Valenzuela, A., and Overall, C.M. (2000). The matrix metalloproteinase gelatinase A in human dentine. Arch. Oral Biol. 45:757-765.
12. Sulkala, M., Wahlgren, J., Larmas, M., Sorsa, T., Teronen, O., Salo, T., and Tjäderhane, L. (2001). The effects of MMP-inhibitors on human salivary MMP activity and caries progression in rats. J. Dent. Res. 80:1545-1549.
13. van Strijp, A.J., Jansen, D.C., DeGroot, J., Ten Cate, J.M., and Everts, V. (2003). Host-derived proteinases and degradation of dentine collagen in situ. Caries Res. 37:58-65.
14. Wahlgren, J., Salo, T., Teronen, O., Luoto, H., Sorsa, T., and Tjäderhane, L. (2002). Matrix metalloproteinase-8 (MMP-8) in pulpal and periapical inflammation and periapical root-canal exudates. Int. Endod. J. 35:897-904.
15. Gusman, H., Santana, R.B., and Zehnder, M. (2002). Matrix metalloproteinase levels and gelatinolytic activity in clinically healthy and inflamed human dental pulps. Eur. J. Oral Sci. 110:353-357. Erratum (2003) Eur. J. Oral Sci. 111: 284.
16. Shin, S.J., Lee, J.I., Back, S.H., and Lim. S.S. (2002). Tissue levels of matrix metalloproteinases in pulps and periapical lesions. J. Endod. 28:313-315.
17. Alizadeh, A.A., Eisen, M.B., Davis, R.E., Ma, C., Lossos, I.S., Rosenwald, A., Boldrick, J.C., Sabet, M., Tran, T., Yu, X., Powell, J.I., Yang, L., Marti, G.E., Moore, T., Hudson, J., Jr., Lu, L., Lewis, D.B., Tibshirani, R., Sherlock, G., Chan, W.C., Greiner, T.C., Weisenburger, D.D., Armitage, J.O., Warnke, R., Levy, R., Wilson, W., Grever, M.R., Byrd, J.C., Botstein, D., Brown, P.O., and Staudt, L.M. (2000). Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403:503-511.
18. Aatsinki, J.T. (1997). Coupled one-step reverse transcription and polymerase chain reaction procedure for cloning large cDNA fragments. Methods Mol. Biol. 67:55-60.
19. Livak, K.J., and Schmittgen, T.D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408.
20. Freije, J.M., Díez-Itza, I., Balbín, M., Sánchez, L.M., Blasco, R., Tovilia, J., and López-Otin, C. (1994). Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas. J. Biol. Chem. 269:16766-16773.
21. Leeman, M.F., Curran, S., and Murray, G.J. (2002). The structure, regulation, and function of human matrix metalloproteinase-13. Crit. Rev. Biochem. Mol. Biol. 37:149-166.
22. Ravanti, L., Häkkinen, L., Larjava, H., Saarialho-Kere, U., Foschi, M., Han, J., and Kähäri, V.M. (1999). Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase. J. Biol. Chem. 274:37292-37300.
23. Johansson, N., Saarialho-Kere, U., Airola, K., Herva, R., Nissinen, L., Westermarck, J., Vuorio, E., Heine, J., and Kähä ri V.M. (1997). Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells. and osteoblasts during human fetal bone development. Dev. Dyn. 208:387-397.
24. Reboul, P., Pelletier, J.P, Tardif, G., Cloutier, J.M., and Martel-Pelletier, J. (1996). The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. J. Clin. Invest. 97:2011-2019.
25. Ståhle-Bäckdahl, M., Sandstedt, B., Bruce, K., Lindahl, A., Jimenez, M.G., Vega, J.A., and Lopez-Otin, C. (1997). Collagenase-3 (MMP-13) is expressed during human fetal ossification and re-expressed in postnatal bone remodeling and in rheumatoid arthritis. Lab. Invest. 76:717-728.
26. Brinckerhoff, C.E., Rutter, J.L., and Benbow, U. (2000). Interstitial collagenases as markers of tumor progression. Clin. Cancer Res. 6:4823-4830.
27. Knäuper, V., López-Otín, C., Smith, B., Knight, G., and Murphy, G. (1996). Biochemical characterization of human collagenase-3. J. Biol. Chem. 271:1544-1550.
28. Knäuper, V., Cowell, S., Smith, B., López-Otín, C., O'Shea, M., Morris, H., Zardi, L., and Murphy, G. (1997). The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interaction. J. Biol. Chem. 272:7608-7616.
29. D'Angelo, M., Billings, P.C., Pacifici, M., Leboy, P.S., and Kirsch, T. (2001). Authentic matrix vesicles contain active metalloproteinases (MMP): A role for matrix vesicle-associated MMP-13 in activation of transforming growth factor-β. J. Biol. Chem. 276:11347-11353.
30. Sloan, A.J., Moseley, R., Dobie, K., Waddington, R.J., and Smith, A.J. (2002). TGF-β latency-associated peptides (LAPs) in human dentin matrix and pulp. Connect. Tissue Res. 43:381-386.
31. Seandel, M., Noack-Krummann, K., Zhu, D., Annes, R.T., and Quigley, J.P. (2001). Growth factor-induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen. Blood 97:2323-2332.
32. Shimada, T., Nakamura, H., Ohuchi, E., Fujii, Y., Murakami, Y., Sato, H., Seiki, M., and Okada, Y. (1999). Characterization of a truncated recombinant form of human membrane type 3 matrix metalloproteinase. Eur. J. Biochem. 262:907-914.
33. van Amerongen, J.P., Lemmens, I.G., and Tonino, G.J.M. (1983). The concentration, extractability and characterization of collagen in human dental pulp. Arch. Oral Biol. 28:339-345.
34. Shapiro, S.D., Kobayashi, D.K., and Ley, T.J. (1993). Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J. Biol. Chem. 268:8170-8175.
35. Chandler, S., Cossins, J., Lury, J., and Wells, G. (1996). Macrophage metalloelastase degrades matrix and myelin proteins and processes a tumour necrosis factor-α fusion protein. Biochem. Biophys. Res. Commun. 228:421-429.
36. Brew, K., Dinakarpandian, D., and Nagase, H. (2000). Tissue inhibitors of metalloproteinases: Evolution, structure and function. Biochim. Biophys. Acta 1477:267-283.