Pentoxifylline does not affect nociception if administered postoperatively

Polish Journal of Pharmacology

Volumn 56, Issue 5, 2004, Pages 611-616

  Szczepanik, Antoni M ^a   Wordliczek, Jerzy ^a   Serednicki, Wojciech ^a   Siedlar, Maciej ^a   Czupryna, Antoni ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Cytokines; Nociception; Pentoxifylline; Postoperative

Indexed keywords

ANALGESIC AGENT; CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; OPIATE ANTAGONIST; PENTOXIFYLLINE; PETHIDINE; PLACEBO; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHOLECYSTECTOMY; CYTOKINE PRODUCTION; DRUG MECHANISM; GENERAL ANESTHESIA; HYPERALGESIA; INFLAMMATION; NOCICEPTION; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD;

HUMANS; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PENTOXIFYLLINE; POSTOPERATIVE CARE;

EID: 12344300191     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Fox DA: Cytokine blockade as a new strategy to treat rheumatoid arthritis: inhibition of tumor necrosis factor. Arch Intern Med, 2000, 160, 437-444.
2. Fukuoka H, Kawatani N, Hisamitsu T, Takeshige C: Cutaneous hyperalgesia induced by peripheral injection of interleukin 1 β in the rat. Brain Res, 1994, 657, 133-140.
3. Popiela T, Szczepanik AM, Wordliczek J, Czupryna A, Siedlar M, Solecki R, Zembala M: Alterations in the early postoperative cytokine response after preoperative pentoxifylline administration. Eur Surg Res, 1999, 31, Suppl 1, 129.
4. Raghavendra V, Tanga F, Rutkowski MD, DeLeo JA: Anti-hyperalgesic and morphine-sparing actions of propentofylline following peripheral nerve injury in rats: mechanistic implications of spinal glia and proinflammatory cytokines. Pain, 2003, 104, 655-664.
5. Sommer C, Kress M: Recent findings on how proinflammatory cytokines cause pain: peripheral mechanisms in inflammatory and neuropathic hyperalgesia. Neurosci Lett, 2004, 361, 184-187.
6. Watkins LR, Wiertelak EP, Goehler LE, Smith KP, Martin D, Maier SF: Characterization of cytokine induced hyperalgesia. Brain Res, 1994, 654, 15-26.
7. Wordliczek J, Szczepanik AM, Banach M, Turchan J, Zembala M, Siedlar M, Przewłocki R et al.: The effect of pentoxifylline on post-injury hyperalgesia in rats and postoperative pain in patients. Life Sci, 2000, 66, 1155-1164.
8. Wordliczek J, Szczepanik AM, Wnek J: The role of cytokines in the nociceptive process (Polish). Ból, 2002, 3, 7-11.